10.1016/s1359-6101(99)00017-9
Crossref journal-article
Elsevier BV
Cytokine & Growth Factor Reviews (78)
Bibliography

Kikuchi, A. (1999). Modulation of Wnt signaling by Axin and Axil. Cytokine & Growth Factor Reviews, 10(3–4), 255–265.

Authors 1
  1. A. Kikuchi (first)
References 99 Referenced 65
  1. 10.1016/0092-8674(92)90630-U / Cell / Wnt genes by Nusse (1992)
  2. 10.1101/gad.11.24.3286 / Genes Dev. / Wnt signaling: a common theme in animal development by Cadigan (1997)
  3. 10.1042/bj3290209 / Biochem. J. / Signal transduction by the Wnt family ligands by Dale (1998)
  4. 10.1101/gad.10.20.2527 / Genes Dev. / Signal transduction through β-catenin and specification of cell fate during embryogenesis by Miller (1996)
  5. 10.1016/S0092-8674(00)80324-4 / Cell / The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation by Zeng (1997)
  6. 10.1093/genetics/22.1.1 / Genetics / The inheritance and expression of Fused, a new mutation in the house mouse by Reed (1937)
  7. 10.1002/jez.1401100105 / J. Exp. Zool. / The effects of a lethal mutation responsible for duplications and twinning in mouse embryos by Gluecksohn-Schoenheimer (1949)
  8. 10.1017/S0016672300025702 / Genet. Res. / Knobbly, a new dominant mutation in the mouse that affects embryonic ectoderm organization by Jacobs-Cohen (1984)
  9. 10.1093/genetics/141.1.321 / Genetics / Phenotypic and molecular analysis of a transgenic insertional allele of the mouse Fused locus by Perry (1995)
  10. 10.1093/emboj/17.5.1371 / EMBO J. / Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3β and β-catenin and promotes GSK-3β-dependent phosphorylation of β-catenin by Ikeda (1998)
  11. 10.1128/MCB.18.5.2867 / Mol. Cell Biol. / Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3β and β-catenin and inhibits axis formation of Xenopus embryos by Yamamoto (1998)
  12. 10.1126/science.280.5363.596 / Science / Functional interaction of an Axin homolog, conductin, with β-catenin, APC, and GSK3β by Behrens (1998)
  13. 10.1016/S0925-4773(98)00203-2 / Mech. Dev. / Xenopus axin interacts with glycogen syntase kinase-3 beta and is expressed in the anterior midbrain by Hedgepeth (1999)
  14. 10.1006/geno.1998.5650 / Genomics / Cloning of the human homolog of conductin (AXIN2), a gene mapping to chromosome 17q23–q24 by Mai (1999)
  15. 10.1126/science.283.5408.1739 / Science / Negative regulation of wingless signaling by D-Axin, a Drosophila homolog of Axin by Hamada (1999)
  16. 10.1242/dev.126.18.4165 / Development / A Drosophila Axin homolog, Daxin, inhibits Wnt signaling by Willert (1999)
  17. 10.1038/367076a0 / Nature / Components of wingless signalling in Drosophila by Siegfried (1994)
  18. 10.1016/S0092-8674(00)81991-1 / Cell / Direct and long-range action of a wingless morphogen gradient by Zecca (1996)
  19. 10.1016/S0955-0674(97)80090-7 / Curr. Opin. Cell Biol. / Dorsal-ventral signaling in limb development by Irvine (1997)
  20. 10.1126/science.273.5280.1373 / Science / Antagonistic interactions between wingless and decapentaplegic responsible for dorsal-ventral pattern in the Drosophila Leg by Brook (1996)
  21. 10.1038/379742a0 / Nature / Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family by Druey (1996)
  22. 10.1006/dbio.1994.1297 / Dev. Biol. / Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled by Sussman (1994)
  23. 10.1074/jbc.273.18.10823 / J. Biol. Chem. / Axin, a negative regulator of the Wnt signaling pathway, directly interacts with Adenomatous Polyposis Coli and regulates the stabilization of β-catenin by Kishida (1998)
  24. 10.1128/MCB.19.6.4414 / Mol. Cell Biol. / DIX domains of Dvl and Axin are necessary for protein interactions and their ability to regulate β-catenin stability by Kishida (1999)
  25. 10.1074/jbc.274.6.3439 / J. Biol. Chem. / Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain by Hsu (1999)
  26. 10.1093/emboj/18.10.2823 / EMBO J. / Interaction of Axin and Dvl-2 proteins regulates Dvl-2 stimulated TCF-dependent transcription by Smalley (1999)
  27. 10.1083/jcb.145.4.741 / J. Cell Biol. / Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization by Fagotto (1999)
  28. 10.1093/emboj/18.15.4233 / EMBO J. / Axin and Frat1 interact with Dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1 by Li (1999)
  29. Ikeda S, Kishida M, Matsuura Y, Usui H, Kikuchi A. KSK-3β-dependent phosphorylation of adenomatous polyposis coli gene product is regulated by β-catenin and protein phosphatase 2A complexed with Axin. Oncogene, in press, 2000 (10.1038/sj.onc.1203359)
  30. {'key': '10.1016/S1359-6101(99)00017-9_BIB30', 'first-page': '147', 'article-title': 'Glycogen synthase kinase-3: functions in oncogenesis and development', 'volume': '1114', 'author': 'Plyte', 'year': '1992', 'journal-title': 'Biochim. Biophys. Acta'} / Biochim. Biophys. Acta / Glycogen synthase kinase-3: functions in oncogenesis and development by Plyte (1992)
  31. 10.1007/BF01025031 / J. Prot. Chem. / Identification of the ATP·Mg-dependent protein phosphatase activator (FA) as a synapsin I kinase that inhibits cross-linking of synapsin I with brain microtubles by Yang (1992)
  32. 10.1016/0014-5793(92)81496-9 / FEBS Lett. / Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule- associated protein tau by Mandelkow (1992)
  33. 10.1126/science.272.5264.1023 / Science / Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly by Rubinfeld (1996)
  34. 10.1002/j.1460-2075.1990.tb07419.x / EMBO J. / Molecular cloning and expression of glycogen synthase kinase-3/Factor A by Woodgett (1990)
  35. 10.1038/362557a0 / Nature / Drosophila shaggy kinase and rat glycogen synthase kinase-3 have conserved activities and act downstream of Notch by Ruel (1993)
  36. 10.1126/science.2006419 / Science / Cadherin cell adhesion receptors as a morphogenetic regulator by Takeichi (1991)
  37. 10.1016/S0092-8674(00)80352-9 / Cell / Three-dimensional structure of the armadillo repeat region of β-catenin by Huber (1997)
  38. 10.1128/MCB.16.8.4088 / Mol. Cell Biol. / Deletion of an amino-terminal sequence stabilizes β-catenin in vivo and promotes hyperphosporylation of the adenomatous polyposis coli tumor suppressor protein by Munemitsu (1996)
  39. 10.1101/gad.10.12.1443 / Genes Dev. / The axis-inducing activity, stability, and subcellular distribution of β-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3 by Yost (1996)
  40. 10.1093/emboj/16.13.3797 / EMBO J. / β-catenin is a target for the ubiquitin-proteasome pathway by Aberle (1997)
  41. 10.1016/0092-8674(94)90396-4 / Cell / The ubiquitin-proteasome proteolytic pathway by Ciechanover (1994)
  42. 10.1016/S0092-8674(00)80403-1 / Cell / F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex by Skowyra (1997)
  43. 10.1016/S0092-8674(00)80404-3 / Cell / A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p by Feldman (1997)
  44. 10.1016/S0092-8674(00)80403-1 / Cell / F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex by Skowyra (1997)
  45. 10.1016/S0092-8674(00)80404-3 / Cell / A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p by Feldman (1997)
  46. 10.1038/35154 / Nature / Regulation of the hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb by Jiang (1998)
  47. 10.1093/emboj/18.9.2401 / EMBO J. / An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of β-catenin by Kitagawa (1999)
  48. 10.1101/gad.13.3.270 / Genes Dev. / The SCFβ-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IκBα and β-catenin and stimulates IκBα ubiquitination in vitro by Winston (1999)
  49. 10.1038/sj.onc.1202653 / Oncogene / The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin by Latres (1999)
  50. 10.1038/25159 / Nature / Identification of the receptor component of the IκBα-ubiquitin ligase by Yaron (1998)
  51. 10.1073/pnas.96.7.3859 / Proc. Natl. Acad. Sci. USA / Ubiquitin-dependent degradation of IκBα is mediated by a ubiquitin ligase SCFFWD1 by Hatakeyama (1999)
  52. 10.1101/gad.13.5.505 / Genes & Dev. / A ubiquitin ligase complex essential for the NF-kB, Wnt/Wingless, and Hedgehog signaling pathways by Maniatis (1999)
  53. 10.1016/S0960-9822(98)70226-X / Curr. Biol. / Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK-3β by Hart (1998)
  54. 10.1038/sj.onc.1202388 / Oncogene / Axin prevents Wnt-3α-induced accumulation of β-catenin by Kishida (1999)
  55. 10.1016/S0955-0674(98)80039-2 / Curr. Opin. Cell Biol. / Differential molecular interactions of beta-catenin and plakoglobin in adhesion, signaling and cancer by Ben-Ze’ev (1998)
  56. 10.1016/0168-9525(93)90250-L / Trends Genet. / From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion by Kemler (1993)
  57. Kodama S, Ikeda S, Asahara T, Kishida M, Kikuchi A. Axin directly interacts with plakoglobin and regulates its stability. J Biol Chem, 1999;274:27682–8 (10.1074/jbc.274.39.27682)
  58. 10.1073/pnas.92.10.4522 / Proc. Natl. Acad. Sci. USA / Anterior axis duplication in Xenopus induced by the over-expression of the cadherin-binding protein plakoglobin by Karnovsky (1995)
  59. 10.1083/jcb.128.5.959 / J. Cell Biol. / Embryonic Axis induction by the armadillo repeat domain of β-catenin: evidence for intracellular signaling by Funayama (1995)
  60. 10.1083/jcb.141.6.1433 / J. Cell Biol. / Differential nuclear translocation and transactivation potential of beta-catenin and plakoglobin by Simcha (1998)
  61. 10.1083/jcb.140.1.183 / J. Cell Biol. / Signaling and adhesion activities of mammalian beta-catenin and plakoglobin in Drosophila by White (1998)
  62. 10.1006/dbio.1997.8550 / Dev. Biol. / Cytoplasmically anchored plakoglobin induces a WNT-like phenotype in Xenopus by Merriam (1997)
  63. {'key': '10.1016/S1359-6101(99)00017-9_BIB63', 'first-page': 'F127', 'article-title': 'The adenomatous polyposis coli (APC) tumor suppressor', 'volume': '1332', 'author': 'Polakis', 'year': '1997', 'journal-title': 'Biochim. Biophys. Acta'} / Biochim. Biophys. Acta / The adenomatous polyposis coli (APC) tumor suppressor by Polakis (1997)
  64. 10.1126/science.8259518 / Science / Association of the APC gene product with β-catenin by Rubinfeld (1993)
  65. 10.1126/science.8259519 / Science / Association of the APC tumor suppressor protein with catenins by Su (1993)
  66. 10.1074/jbc.270.10.5549 / J. Biol. Chem. / The APC protein and E-cadherin form similar but independent complexes with α-catenin, β-catenin, and plakoglobin by Rubinfeld (1995)
  67. 10.1126/science.272.5264.1020 / Science / Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein by Matsumine (1996)
  68. {'key': '10.1016/S1359-6101(99)00017-9_BIB68', 'first-page': '4624', 'article-title': 'Loss of β-catenin regulation by the APC tumor suppressor protein correlates with loss of structure due to common somatic mutations of the gene', 'volume': '57', 'author': 'Rubinfeld', 'year': '1997', 'journal-title': 'Cancer Res.'} / Cancer Res. / Loss of β-catenin regulation by the APC tumor suppressor protein correlates with loss of structure due to common somatic mutations of the gene by Rubinfeld (1997)
  69. 10.1074/jbc.274.16.10681 / J. Biol. Chem. / Phosphorylation of Axin, a Wnt signal negative regulator, by glycogen synthase kinase-3β regulates its stability by Yamamoto (1999)
  70. 10.1101/gad.13.14.1768 / Genes & Dev. / Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex by Willert (1999)
  71. 10.1101/gad.8.1.118 / Genes Dev. / The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal by Klingensmith (1994)
  72. 10.1242/dev.120.2.347 / Development / Dishevelled is required during wingless signaling to establish both cell polarity and cell identity by Theisen (1994)
  73. 10.1016/S0925-4773(96)00549-7 / Mech. Dev. / Conservation of dishevelled structure and function between flies and mice: Isolation and characterization of Dvl2 by Klingensmith (1996)
  74. 10.1093/hmg/5.7.953 / Hum. Mol. Genet. / cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene by Pizzuti (1996)
  75. 10.1016/S0960-9822(96)00750-6 / Curr. Biol. / Analysis of Dishevelled signaling pathways during Xenopus development by Sokol (1996)
  76. 10.1101/gad.9.9.1087 / Genes Dev. / The Dishevelled protein is modified by Wingless signaling in Drosophila by Yanagawa (1995)
  77. 10.1074/jbc.272.40.25243 / J. Biol. Chem. / Accumulation of Armadillo induced by Wingless, Dishevelled, and dominant-negative Zeste-white 3 leads to elevated DE-cadherin in Drosophila clone 8 wing disc cells by Yanagawa (1997)
  78. 10.1016/S0092-8674(00)81226-X / Cell / Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling by Boutros (1998)
  79. 10.1074/jbc.274.1.129 / J. Biol. Chem. / Dishevelled proteins lead to two signaling pathways by Li (1999)
  80. 10.1016/S0014-5793(97)00733-3 / FEBS Lett. / Overexpression of the mouse dishevelled-1 protein inhibits GSK-3β-mediated phosphorylation of tau in transfected mammalian cells by Wagner (1997)
  81. 10.1146/annurev.bi.58.070189.002321 / Annu. Rev. Biochem. / The structure and regulation of protein phosphatase by Cohen (1989)
  82. 10.1042/bj3110017 / Biochem. J. / Serine/threonine protein phosphatases by Wera (1995)
  83. 10.1126/science.276.5314.952 / Science / Regulation of protein phosphatase 2A by direct interaction with casein kinase 2 alpha by Heriche (1997)
  84. 10.1126/science.280.5367.1258 / Science / A signaling complex of Ca2+-calmodulin-dependent protein kinase IV and protein phosphatase 2A by Westphal (1998)
  85. 10.1126/science.283.5410.2089 / Science / Regulation of beta-Catenin Signaling by the B56 Subunit of Protein Phosphatase 2A by Seeling (1999)
  86. 10.1074/jbc.274.20.14090 / J. Biol. Chem. / Functional domains of axin: Importance of the C terminus as an oligomerization domain by Sakanaka (1999)
  87. 10.1128/MCB.14.9.6278 / Mol. Cell Biol. / Differential transformation of mammary epithelial cells by Wnt genes by Wong (1994)
  88. 10.1128/MCB.15.5.2625 / Mol. Cell Biol. / Identification of distinct classes and functional domains of Wnts through expression of wild-type and chimeric proteins in Xenopus embryos by Du (1995)
  89. {'key': '10.1016/S1359-6101(99)00017-9_BIB89', 'first-page': '1349', 'article-title': 'Transformation by Wnt family proteins correlates with regulation of β-catenin', 'volume': '8', 'author': 'Shimizu', 'year': '1997', 'journal-title': 'Cell Growth Differ.'} / Cell Growth Differ. / Transformation by Wnt family proteins correlates with regulation of β-catenin by Shimizu (1997)
  90. 10.1093/emboj/16.3.441 / EMBO J. / Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas by Jonkers (1997)
  91. 10.1016/S0092-8674(00)81208-8 / Cell / GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis by Yost (1998)
  92. 10.1006/dbio.1996.0306 / Dev. Biol. / Activation of Siamois by the Wnt pathway by Brannon (1996)
  93. 10.1016/S0092-8674(00)81924-8 / Cell / LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic by Riese (1997)
  94. 10.1126/science.281.5382.1509 / Science / Identification of c-MYC as a target of the APC Pathway by He (1998)
  95. 10.1073/pnas.96.4.1603 / Proc. Natl. Acad. Sci. USA / Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas by Mann (1999)
  96. 10.1038/18884 / Nature / β-catenin regulates expression of cyclin D1 in colon carcinoma cells by Tetsu (1999)
  97. 10.1038/26982 / Nature / Drosophila Tcf and Groucho interact to repress Wingless signalling activity by Cavallo (1998)
  98. 10.1038/26785 / Nature / Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling by Waltzer (1998)
  99. 10.1038/21674 / Nature / The TAK1-NLK-MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF by Ishitani (1999)
Dates
Type When
Created 23 years, 1 month ago (July 25, 2002, 11:13 a.m.)
Deposited 4 years, 3 months ago (May 7, 2021, 2:39 p.m.)
Indexed 3 weeks, 6 days ago (Aug. 5, 2025, 9:01 a.m.)
Issued 26 years ago (Sept. 1, 1999)
Published 26 years ago (Sept. 1, 1999)
Published Print 26 years ago (Sept. 1, 1999)
Funders 0

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@article{Kikuchi_1999, title={Modulation of Wnt signaling by Axin and Axil}, volume={10}, ISSN={1359-6101}, url={http://dx.doi.org/10.1016/s1359-6101(99)00017-9}, DOI={10.1016/s1359-6101(99)00017-9}, number={3–4}, journal={Cytokine & Growth Factor Reviews}, publisher={Elsevier BV}, author={Kikuchi, A.}, year={1999}, month=sep, pages={255–265} }