Crossref journal-article
Elsevier BV
Cytokine & Growth Factor Reviews (78)
Bibliography

Padgett, R. W., Savage, C., & Das, P. (1997). Genetic and biochemical analysis of TGFβ signal transduction. Cytokine & Growth Factor Reviews, 8(1), 1–9.

Authors 3
  1. Richard W Padgett (first)
  2. Cathy Savage (additional)
  3. Pradeep Das (additional)
References 75 Referenced 23
  1. {'key': '10.1016/S1359-6101(96)00050-0_BIB1', 'first-page': '5339', 'article-title': 'New class of transforming growth factors potentiated by epidermal growth factor', 'volume': '78', 'author': 'Roberts', 'year': '1981'} / New class of transforming growth factors potentiated by epidermal growth factor by Roberts (1981)
  2. 10.1038/325081a0 / Nature / A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family by Padgett (1987)
  3. {'key': '10.1016/S1359-6101(96)00050-0_BIB3', 'first-page': '2905', 'article-title': 'Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo', 'volume': '90', 'author': 'Padgett', 'year': '1993'} / Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo by Padgett (1993)
  4. {'key': '10.1016/S1359-6101(96)00050-0_BIB4', 'first-page': '6004', 'article-title': 'Drosophila transforming growth factor beta superfamily proteins induce endochondral bone formation in mammals', 'volume': '90', 'author': 'Sampath', 'year': '1993'} / Drosophila transforming growth factor beta superfamily proteins induce endochondral bone formation in mammals by Sampath (1993)
  5. 10.1101/gad.8.21.2588 / Genes Dev / The screw gene encodes a ubiquitously expressed member of the TGFβ family required for specification of dorsal cell fates in the Drosophila embryo by Arora (1994)
  6. {'key': '10.1016/S1359-6101(96)00050-0_BIB6', 'first-page': '9214', 'article-title': 'Drosophila 60A gene, another transforming growth factor beta family member, is closely related to human bone morphogenetic proteins', 'volume': '88', 'author': 'Wharton', 'year': '1991'} / Drosophila 60A gene, another transforming growth factor beta family member, is closely related to human bone morphogenetic proteins by Wharton (1991)
  7. 10.1016/0012-1606(92)90188-M / Dev Biol / Sequence, biochemical characterization, and developmental expression of a new member of the TGFβ superfamily in Drosophila melanogaster by Doctor (1992)
  8. 10.1016/0092-8674(82)90199-4 / Cell / Decapentaplegic: a gene complex affecting development in Drosophila melanogaster by Spencer (9182)
  9. 10.1101/gad.1.8.868 / Genes Dev / The decapentaplegic gene is required for dorso-ventral patterning of the Drosophila embryo by Irish (1987)
  10. 10.1093/genetics/109.1.119 / Genetics / Shortvein, a new component of the decapentaplegic gene complex in Drosophila melanogaster by Segal (1985)
  11. 10.1038/368032a0 / Nature / 2.2 Mb of contiguous nucletide sequence from chromosome III of C. elegans by Wilson (1994)
  12. 10.1126/science.274.5291.1389 / Science / Control of C. elegans larval development by neuronal expression of a TGF-β homolog by Ren (1996)
  13. 10.1101/gad.8.2.133 / Genes Dev / The TGF-β superfamily: new members, new receptors, and new genetic tests of function in different organisms by Kingsley (1994)
  14. 10.1016/0167-4889(94)90026-4 / Biochem Biophys Acta / TGF-β receptors and actions by Attisano (1994)
  15. 10.1016/0962-8924(93)90195-7 / Trends Cell Biol / Receptors for the TGF-β superfamily by Lin (1993)
  16. 10.1016/S0065-2776(08)60510-6 / Adv Immunol / Receptors for transforming growth factor-β by Miyazano (1994)
  17. 10.1038/370341a0 / Nature / Mechanism of activation of the TGFβ receptor by Wrana (1994)
  18. {'key': '10.1016/S1359-6101(96)00050-0_BIB18', 'first-page': '5581', 'volume': '13', 'author': 'Ventura', 'year': '1994', 'journal-title': 'Reconstitution and transphosphorylation of TGFβ receptor complexes'} / Reconstitution and transphosphorylation of TGFβ receptor complexes by Ventura (1994)
  19. 10.1128/MCB.15.7.3479 / Molec Cell Biol / Human type II receptor for bone morphogenetic proteins (BMPs): extension of the two-kinase receptor model to the BMPs by Liu (1995)
  20. 10.1074/jbc.270.38.22522 / J Biol Chem / Identification of a human type II receptor for bone morphogenetic protein-4 that forms differential heteromeric complexes with bone morphogenetic protein type I receptors by Nohno (1995)
  21. {'key': '10.1016/S1359-6101(96)00050-0_BIB21', 'first-page': '7632', 'article-title': 'Cloning and characterization of a human type II receptor for bone morphogenetic proteins', 'volume': '92', 'author': 'Rosenzweig', 'year': '1995'} / Cloning and characterization of a human type II receptor for bone morphogenetic proteins by Rosenzweig (1995)
  22. 10.1016/0092-8674(94)90295-X / Cell / Characterization and relationship of dpp receptors encoded by the saxophone and thick veins genes in Drosophila by Brummel (1994)
  23. 10.1016/0092-8674(94)90294-1 / Cell / Identification of two Bone Morphogenetic Protein type I receptors in Drosophila and evidence that brk25D is a decapentaplegic receptor by Penton (1994)
  24. 10.1016/0092-8674(95)90293-7 / Cell / Drosophila dpp signaling is mediated by the punt gene product: a dual ligand-binding type II receptor for the TGFβ receptor family by Letsou (1995)
  25. 10.1083/jcb.126.1.139 / J Cell Biol / The type II and III transforming growth factor-β receptors form homooligomers by Henis (1994)
  26. 10.1016/S0021-9258(17)32142-7 / J Biol Chem / Formation of hetero-oligomeric complexes of type I and type II receptors for transforming growth factor β by Yamashita (1994)
  27. 10.1016/S0021-9258(17)31725-8 / J Biol Chem / Homomeric interactions between type II transforming growth factor-β receptors by Chen (1994)
  28. {'key': '10.1016/S1359-6101(96)00050-0_BIB28', 'first-page': '276', 'volume': '15', 'author': 'Weis-Garcia', 'year': '1996', 'journal-title': 'Complementation between kinase-defective and activation-defective TGF-β receptors reveals a novel form of receptor cooperativity essential for signalling'} / Complementation between kinase-defective and activation-defective TGF-β receptors reveals a novel form of receptor cooperativity essential for signalling by Weis-Garcia (1996)
  29. 10.1074/jbc.270.41.24237 / J Biol Chem / Transforming growth factor-β (TGFβ)-induced down-regulation of cyclin A expression requires a functional TGFβ receptor complex: characterization of chimeric and truncated type I and type II receptors by Feng (1995)
  30. 10.1016/S0021-9258(18)47342-5 / J. Biol Chem / Distinct roles of the intracellular domains of transforming growth factor-β type I and type II receptors in signal transduction by Okadome (1995)
  31. 10.1074/jbc.270.13.7134 / J Biol Chem / Signaling activity of homologous and heterologous TGFβ receptor kinase complexes by Vivien (1995)
  32. 10.1016/S0092-8674(00)81114-9 / Cell / Direct and long-range action of a DPP morphogen gradient by Nellen (1996)
  33. 10.1074/jbc.271.36.21758 / J Biol Chem / Chimeric granulocyte/macrophage colony stimulating factor/transforming growth factor-fl (TGF-β) receptors define a model system for investigating the role of homomeric and heteromeric receptors in TGFβ signaling by Anders (1996)
  34. {'key': '10.1016/S1359-6101(96)00050-0_BIB34', 'first-page': '4485', 'volume': '15', 'author': 'Luo', 'year': '1996', 'journal-title': 'Signaling by chimeric erythropoietin-TGF-β receptors: homodimerization of the cytoplasmic domain of the type I TGF-β receptor and heterodimerization with the type II receptor are both required for intracellular signal transduction'} / Signaling by chimeric erythropoietin-TGF-β receptors: homodimerization of the cytoplasmic domain of the type I TGF-β receptor and heterodimerization with the type II receptor are both required for intracellular signal transduction by Luo (1996)
  35. 10.1016/0012-1606(84)90201-X / Dev Biol / The Caenorhabditis elegans dauer larva: developmental effects of pheromone, food and temperature by Golden (1984)
  36. 10.1038/290668a0 / Nature / Interacting genes in nematode dauer larva formation by Riddle (1981)
  37. 10.1016/0012-1606(86)90314-3 / Dev Biol / Mutant sensory cilia in the nematode Caenorhabditis elegans by Perkins (1986)
  38. 10.1093/genetics/130.1.105 / Genetics / Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans by Vowels (1992)
  39. 10.1016/0092-8674(90)90475-T / Cell / daf-1, a C. elegans gene controlling dauer larva development, encodes a novel receptor protein kinase by Georgi (1990)
  40. 10.1038/365644a0 / Nature / The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larvae development by Estevez (1993)
  41. 10.1126/science.8388127 / Science / Cloning of a type I TGF-β receptor and its effect on TGF-β binding to the type II receptor by Ebner (1993)
  42. {'key': '10.1016/S1359-6101(96)00050-0_BIB42', 'first-page': '790', 'article-title': 'Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor β pathway components', 'volume': '93', 'author': 'Savage', 'year': '1996'} / Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor β pathway components by Savage (1996)
  43. 10.1126/science.8134837 / Science / The Drosophila saxophone gene: a serine-threonine kinase receptor of the TGF-β superfamily by Xie (1994)
  44. 10.1016/0092-8674(94)90293-3 / Cell / Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic by Nellen (1994)
  45. 10.1093/genetics/139.1.241 / Genetics / Genetic screens to identify elements of the decapentaplegic signaling pathway in Drosophila by Raftery (1995)
  46. 10.1093/genetics/139.3.1347 / Genetics / Genetic characterization and cloning of Mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster by Sekelsky (1995)
  47. 10.1007/BF00848156 / Roux's Arch dev Biol / Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster by Nüsslein-Volhard (1984)
  48. 10.1007/BF00848157 / Roux's Arch Dev Biol / Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster II. Zygotic loci on the third chromosome by Jürgens (1984)
  49. 10.1093/genetics/129.4.1119 / Genetics / Female sterile mutations on the second chromosome of Drosophila melanogaster II. Mutations blocking oogenesis or altering egg morphology by Shüpbach (1991)
  50. 10.1093/genetics/103.1.43 / Genetics / Male phenotypes and mating efficiency in C. elegans by Hodgkin (1983)
  51. 10.1242/dev.113.2.515 / Development / Pattern formation in the nematode epidermis: determination of the arrangement of peripheral sense organs in the C. elegans male tail by Baird (1991)
  52. 10.1016/S0092-8674(00)81335-5 / Cell / Nomenclature: vertebrate mediators of TGFβ family signals by Derynck (1996)
  53. 10.1242/dev.122.7.2099 / Development / Mothers against dpp encodes a conserved cytoplasmic protein required in DPP/TGF-β responsive cells by Newfeld (1996)
  54. 10.1016/S0092-8674(00)81250-7 / Cell / MADRI, a MAD-related protein that functions in BMP2 signalling pathways by Hoodless (1996)
  55. 10.1242/dev.122.7.2153 / Development / Mad acts downstream of receptors, revealing a differential requirement for dpp signaling in initiation and propagation of morphogenesis in the Drosophila eye by Wiersdorff (1996)
  56. 10.1038/383168a0 / Nature / Receptor-associated Mad homologues synergize as effectors of the TGFβ response by Zhang (1996)
  57. 10.1016/S0092-8674(00)80128-2 / Cell / MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma by Eppert (1996)
  58. 10.1074/jbc.271.30.17617 / J. Biol. Chem. / Serine phosphorylation, chromosomal localization and Transforming Growth Fac tor-β signal transduction by human bsp-1 by Leichleider (1996)
  59. 10.1038/381620a0 / Nature / A human Mad protein acting as a BMP-regulated transcriptional activator by Liu (1996)
  60. {'key': '10.1016/S1359-6101(96)00050-0_BIB60', 'first-page': '8940', 'article-title': 'Mammalian Dwarfins are phosphorylated in response to TGFβ and are implicated in control of cell growth', 'volume': '93', 'author': 'Yingling', 'year': '1996'} / Mammalian Dwarfins are phosphorylated in response to TGFβ and are implicated in control of cell growth by Yingling (1996)
  61. 10.1101/gad.10.15.1880 / Genes Der / A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway by Baker (1996)
  62. 10.1038/383691a0 / Nature / A transcriptional partner for MAD proteins in TGF-β signalling by Chen (1996)
  63. 10.1016/S0092-8674(00)81249-0 / Cell / Xenopus Mad proteins transduce distinct subsets of signals for the TGFβ superfamily by Graff (1996)
  64. 10.1242/dev.122.8.2359 / Development / Xenopus mothers against dpp is an embryonic ventralizing agent that acts downstream of the BMP-2/4 receptor by Thomsen (1996)
  65. 10.1016/0092-8674(95)90539-1 / Cell / The Drosophila schnurri gene acts in the Dpp/TGFβ signaling pathway and encodes a transcription factor homologous to the human MBP family by Arora (1995)
  66. 10.1016/0092-8674(95)90540-5 / Cell / schnurri is required for Drosophila dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-bF1 by Grieder (1995)
  67. 10.1242/dev.121.10.3393 / Development / A Drosophila protein related to the human zinc finger transcription factor PRDII/MbPI/HIV-EP1 is required for dpp signaling by Staehling-Hampton (1995)
  68. 10.1126/science.271.5255.1601 / Science / Control of the gene optomotorblind in Drosophila wing development by decapentaplegic and wingless by Grimm (1996)
  69. 10.1038/381421a0 / Nature / A gene complex acting downstream of dpp in Drosophila wing morphogenesis by de Celis (1996)
  70. 10.1038/381387a0 / Nature / Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing by Lecuit (1996)
  71. 10.1126/science.7761852 / Science / Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability by Markowitz (1995)
  72. 10.1016/1359-6101(96)00001-9 / Cytokine Growth Factor Rev / Tumor suppressor activity of the TGF-β pathway in human cancers by Markowitz (1996)
  73. 10.1126/science.271.5247.350 / Science / DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1 by Hahn (1996)
  74. 10.1038/ng0796-347 / Nature Genet. / Mad-related genes in the human by Riggins (1996)
  75. 10.1126/science.270.5244.2008 / Science / Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction by Yamaguchi (1995)
Dates
Type When
Created 23 years ago (July 25, 2002, 8:10 a.m.)
Deposited 4 years, 3 months ago (May 5, 2021, 10:31 a.m.)
Indexed 4 months, 2 weeks ago (April 6, 2025, 1:46 p.m.)
Issued 28 years, 5 months ago (March 1, 1997)
Published 28 years, 5 months ago (March 1, 1997)
Published Print 28 years, 5 months ago (March 1, 1997)
Funders 0

None

@article{Padgett_1997, title={Genetic and biochemical analysis of TGFβ signal transduction}, volume={8}, ISSN={1359-6101}, url={http://dx.doi.org/10.1016/s1359-6101(96)00050-0}, DOI={10.1016/s1359-6101(96)00050-0}, number={1}, journal={Cytokine & Growth Factor Reviews}, publisher={Elsevier BV}, author={Padgett, Richard W and Savage, Cathy and Das, Pradeep}, year={1997}, month=mar, pages={1–9} }