DOI: 10.1016/s1097-2765(01)00240-4. HIV-1 Infection Requires a Functional Integrase NLS

HIV-1 Infection Requires a Functional Integrase NLS

10.1016/s1097-2765(01)00240-4

Crossref journal-article

Elsevier BV

Molecular Cell (78)

Bibliography

Bouyac-Bertoia, M., Dvorin, J. D., Fouchier, R. A. M., Jenkins, Y., Meyer, B. E., Wu, L. I., Emerman, M., & Malim, M. H. (2001). HIV-1 Infection Requires a Functional Integrase NLS. Molecular Cell, 7(5), 1025â1035.

Authors 8

Michèle Bouyac-Bertoia (first)
Jeffrey D Dvorin (additional)
Ron A.M Fouchier (additional)
Yonchu Jenkins (additional)
Barbara E Meyer (additional)
Lily I Wu (additional)
Michael Emerman (additional)
Michael H Malim (additional)

References 51 Referenced 164

10.1006/meth.1997.0487 / Methods / Production of high titer human immunodeficiency virus type 1 pseudotyped with vesicular stomatitis virus glycoprotein by Bartz (1997)
10.1016/0092-8674(87)90287-X / Cell / Correct integration of retroviral DNA in vitro by Brown (1987)
10.1073/pnas.93.1.367 / Proc. Natl. Acad. Sci. USA / Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA by Bukrinskaya (1996)
10.1073/pnas.89.14.6580 / Proc. Natl. Acad. Sci. USA / Active nuclear import of human immunodeficiency virus type 1 preintegration complexes by Bukrinsky (1992)
10.1038/365666a0 / Nature / A nuclear localization signal within HIV-1 matrix protein that governs infection of nondividing cells by Bukrinsky (1993)
10.1073/pnas.150220297 / Proc. Natl. Acad. Sci. USA / Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains by Chen (2000)
10.1126/science.1738845 / Science / Reversal of integration and DNA splicing mediated by integrase of human immunodeficiency virus by Chow (1992)
10.1128/JVI.69.4.2068-2074.1995 / J. Virol. / Peripheral blood mononuclear cells produce normal amounts of defective Vif− human immunodeficiency virus type 1 particle which are restricted for the preretrotranscription steps by Courcoul (1995)
10.1083/jcb.150.3.433 / J. Cell Biol. / The dynamics of postmitotic reassembly of the nucleolus by Dundr (2000)
10.1126/science.7801124 / Science / Crystal structure of the catalytic domain of HIV-1 integrase by Dyda (1994)
10.1016/S0065-3527(08)60309-7 / Adv. Virus Res. / In vivo analysis of retroviral integrase structure and function by Engelman (1999)
10.1016/S0065-3527(08)60304-8 / Adv. Virus Res. / HIV integrase structure and function by Esposito (1999)
10.1128/JVI.65.4.1910-1915.1991 / J. Virol. / Determination of viral proteins present in the human immunodeficiency virus type 1 preintegration complex by Farnet (1991)
10.1016/S0092-8674(00)81888-7 / Cell / HIV-1 cDNA integration by Farnet (1997)
10.1093/emboj/16.16.5123 / EMBO J. / Complementation of intergrase function in HIV-1 virions by Fletcher (1997)
10.1016/S0065-3527(08)60302-4 / Adv. Virus Res. / Nuclear import of human immunodeficiency virus type-1 pre-integration complexes by Fouchier (1999)
10.1093/emboj/16.15.4531 / EMBO J. / HIV-1 infection of nondividing cells by Fouchier (1997)
10.1128/JVI.72.7.6004-6013.1998 / J. Virol. / Interaction of the human immunodeficiency virus type 1 Vpr protein with the nuclear pore complex by Fouchier (1998)
10.1006/viro.1998.9398 / Virology / HIV-1 gag proteins by Freed (1998)
10.1016/0092-8674(95)90488-3 / Cell / HIV-1 infection of nondividing cells by Gallay (1995)
10.1073/pnas.94.18.9825 / Proc. Natl. Acad. Sci. USA / HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway by Gallay (1997)
10.1128/JVI.72.6.4678-4685.1998 / J. Virol. / Mutations in the human immunodeficiency virus type 1 integrase D,D(35)E motif do not eliminate provirus formation by Gaur (1998)
10.1093/emboj/16.19.5998 / EMBO J. / The role of the nuclear pore complex in adenovirus DNA entry by Greber (1997)
10.1073/pnas.91.15.7311 / Proc. Natl. Acad. Sci. USA / The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells by Heinzinger (1994)
10.1016/0022-2836(67)90307-5 / J. Mol. Biol. / Selective extraction of polyoma DNA from infected mouse cell cultures by Hirt (1967)
10.1093/emboj/17.14.4114 / EMBO J. / Snurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structure by Huber (1998)
10.1074/jbc.271.13.7712 / J. Biol. Chem. / A soluble active mutant of HIV-1 integrase by Jenkins (1996)
{'key': '10.1016/S1097-2765(01)00240-4_BIB28', 'series-title': 'Advances in Molecular Biology and Targeted Treatment for AIDS', 'article-title': 'Analysis of HIV integration components', 'author': 'Jones', 'year': '1991'} / Advances in Molecular Biology and Targeted Treatment for AIDS / Analysis of HIV integration components by Jones (1991)
10.1126/science.7801128 / Science / Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5 by Kalpana (1994)
10.1128/JVI.66.4.2232-2239.1992 / J. Virol. / Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated β-galactosidase gene by Kimpton (1992)
{'key': '10.1016/S1097-2765(01)00240-4_BIB31', 'series-title': 'Human Retroviruses and AIDS', 'author': 'Kuiken', 'year': '1999'} / Human Retroviruses and AIDS by Kuiken (1999)
10.1002/j.1460-2075.1992.tb05376.x / EMBO J. / Human immunodeficiency virus infection of cells arrested in the cell cycle by Lewis (1992)
10.1128/JVI.68.1.510-516.1994 / J. Virol. / Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus by Lewis (1994)
10.1128/JVI.72.3.2208-2212.1998 / J. Virol. / Cytosolic Gag p24 as an index of productive entry of human immunodeficiency virus type 1 by Maréchal (1998)
10.1146/annurev.biochem.67.1.265 / Annu. Rev. Biochem. / Nucleocytoplasmic transport by Mattaj (1998)
10.1128/JVI.71.7.5382-5390.1997 / J. Virol. / Human immunodeficiency virus type 1 preintegration complexes by Miller (1997)
10.1128/JVI.73.3.2343-2349.1999 / J. Virol. / Primary human immunodeficiency virus type 2 (HIV-2) isolates, like HIV- 1 isolates, frequently use CCR5 but show promiscuity in coreceptor usage by Morner (1999)
10.1128/JVI.74.21.10074-10080.2000 / J. Virol. / Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding by O'Doherty (2000)
10.1128/JVI.73.6.5079-5088.1999 / J. Virol. / Oligomerization within virions and subcellular localization of human immunodeficiency virus type 1 integrase by Petit (1999)
10.1128/JVI.74.15.7119-7126.2000 / J. Virol. / The karyophilic properties of human immunodeficiency virus type 1 integrase are not required for nuclear import of proviral DNA by Petit (2000)
10.1006/viro.1999.9727 / Virology / Nuclear localization of human immunodeficiency virus type 1 integrase expressed as a fusion protein with green fluorescent protein by Pluymers (1999)
10.1074/jbc.273.21.13347 / J. Biol. Chem. / Viral protein R regulates docking of the HIV-1 preintegration complex to the nuclear pore complex by Popov (1998)
10.1093/emboj/17.9.2699 / EMBO J. / Efficient HIV-1 replication can occur in the absence of the viral matrix protein by Reil (1998)
10.1002/j.1460-2075.1993.tb05858.x / EMBO J. / Integration of murine leukemia virus DNA depends on mitosis by Roe (1993)
10.1002/j.1460-2075.1990.tb08274.x / EMBO J. / HIV-1 replication is controlled at the level of T cell activation and proviral integration by Stevenson (1990)
10.1006/viro.1997.8606 / Virology / Indicator cell lines for detection of primary strains of human and simian immunodeficiency viruses by Vodicka (1997)
10.1101/gad.12.2.175 / Genes Dev. / HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection by Vodicka (1998)
10.1084/jem.174.6.1477 / J. Exp. Med. / Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes by Weinberg (1991)
10.1128/JVI.69.1.376-386.1995 / J. Virol. / Human immunodeficiency virus type 1 integrase by Wiskerchen (1995)
10.1093/emboj/16.16.5113 / EMBO J. / Functional RT and IN incorporated into HIV-1 particles independently of the Gag/Pol precursor protein by Wu (1997)
10.1016/S0092-8674(00)80828-4 / Cell / HIV-1 genome nuclear import is mediated by a central DNA flap by Zennou (2000)

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 7:02 p.m.)
Deposited	5 years, 7 months ago (Feb. 4, 2020, 8:37 p.m.)
Indexed	2 months ago (July 2, 2025, 10:18 a.m.)
Issued	24 years, 4 months ago (May 1, 2001)
Published	24 years, 4 months ago (May 1, 2001)
Published Print	24 years, 4 months ago (May 1, 2001)

Funders 0

None

BibTeX

@article{Bouyac_Bertoia_2001, title={HIV-1 Infection Requires a Functional Integrase NLS}, volume={7}, ISSN={1097-2765}, url={http://dx.doi.org/10.1016/s1097-2765(01)00240-4}, DOI={10.1016/s1097-2765(01)00240-4}, number={5}, journal={Molecular Cell}, publisher={Elsevier BV}, author={Bouyac-Bertoia, Michèle and Dvorin, Jeffrey D and Fouchier, Ron A.M and Jenkins, Yonchu and Meyer, Barbara E and Wu, Lily I and Emerman, Michael and Malim, Michael H}, year={2001}, month=may, pages={1025–1035} }

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      "year": "1992",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
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      "article-title": "A nuclear localization signal within HIV-1 matrix protein that governs infection of nondividing cells",
      "volume": "365",
      "author": "Bukrinsky",
      "year": "1993",
      "journal-title": "Nature"
    },
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      "first-page": "8233",
      "DOI": "10.1073/pnas.150220297",
      "article-title": "Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains",
      "volume": "97",
      "author": "Chen",
      "year": "2000",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
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      "DOI": "10.1126/science.1738845",
      "article-title": "Reversal of integration and DNA splicing mediated by integrase of human immunodeficiency virus",
      "volume": "255",
      "author": "Chow",
      "year": "1992",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB8",
      "doi-asserted-by": "crossref",
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      "volume": "69",
      "author": "Courcoul",
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    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB9",
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      "author": "Heinzinger",
      "year": "1994",
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      "volume": "26",
      "author": "Hirt",
      "year": "1967",
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      "first-page": "7712",
      "DOI": "10.1074/jbc.271.13.7712",
      "article-title": "A soluble active mutant of HIV-1 integrase",
      "volume": "271",
      "author": "Jenkins",
      "year": "1996",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB28",
      "series-title": "Advances in Molecular Biology and Targeted Treatment for AIDS",
      "article-title": "Analysis of HIV integration components",
      "author": "Jones",
      "year": "1991"
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "2002",
      "DOI": "10.1126/science.7801128",
      "article-title": "Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5",
      "volume": "266",
      "author": "Kalpana",
      "year": "1994",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "2232",
      "DOI": "10.1128/JVI.66.4.2232-2239.1992",
      "article-title": "Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated \u03b2-galactosidase gene",
      "volume": "66",
      "author": "Kimpton",
      "year": "1992",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB31",
      "series-title": "Human Retroviruses and AIDS",
      "author": "Kuiken",
      "year": "1999"
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "3053",
      "DOI": "10.1002/j.1460-2075.1992.tb05376.x",
      "article-title": "Human immunodeficiency virus infection of cells arrested in the cell cycle",
      "volume": "11",
      "author": "Lewis",
      "year": "1992",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "510",
      "DOI": "10.1128/JVI.68.1.510-516.1994",
      "article-title": "Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus",
      "volume": "68",
      "author": "Lewis",
      "year": "1994",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "2208",
      "DOI": "10.1128/JVI.72.3.2208-2212.1998",
      "article-title": "Cytosolic Gag p24 as an index of productive entry of human immunodeficiency virus type 1",
      "volume": "72",
      "author": "Mar\u00e9chal",
      "year": "1998",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "265",
      "DOI": "10.1146/annurev.biochem.67.1.265",
      "article-title": "Nucleocytoplasmic transport",
      "volume": "67",
      "author": "Mattaj",
      "year": "1998",
      "journal-title": "Annu. Rev. Biochem."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "5382",
      "DOI": "10.1128/JVI.71.7.5382-5390.1997",
      "article-title": "Human immunodeficiency virus type 1 preintegration complexes",
      "volume": "71",
      "author": "Miller",
      "year": "1997",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "2343",
      "DOI": "10.1128/JVI.73.3.2343-2349.1999",
      "article-title": "Primary human immunodeficiency virus type 2 (HIV-2) isolates, like HIV- 1 isolates, frequently use CCR5 but show promiscuity in coreceptor usage",
      "volume": "73",
      "author": "Morner",
      "year": "1999",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "10074",
      "DOI": "10.1128/JVI.74.21.10074-10080.2000",
      "article-title": "Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding",
      "volume": "74",
      "author": "O'Doherty",
      "year": "2000",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "5079",
      "DOI": "10.1128/JVI.73.6.5079-5088.1999",
      "article-title": "Oligomerization within virions and subcellular localization of human immunodeficiency virus type 1 integrase",
      "volume": "73",
      "author": "Petit",
      "year": "1999",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "7119",
      "DOI": "10.1128/JVI.74.15.7119-7126.2000",
      "article-title": "The karyophilic properties of human immunodeficiency virus type 1 integrase are not required for nuclear import of proviral DNA",
      "volume": "74",
      "author": "Petit",
      "year": "2000",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "327",
      "DOI": "10.1006/viro.1999.9727",
      "article-title": "Nuclear localization of human immunodeficiency virus type 1 integrase expressed as a fusion protein with green fluorescent protein",
      "volume": "258",
      "author": "Pluymers",
      "year": "1999",
      "journal-title": "Virology"
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "13347",
      "DOI": "10.1074/jbc.273.21.13347",
      "article-title": "Viral protein R regulates docking of the HIV-1 preintegration complex to the nuclear pore complex",
      "volume": "273",
      "author": "Popov",
      "year": "1998",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "2699",
      "DOI": "10.1093/emboj/17.9.2699",
      "article-title": "Efficient HIV-1 replication can occur in the absence of the viral matrix protein",
      "volume": "17",
      "author": "Reil",
      "year": "1998",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "2099",
      "DOI": "10.1002/j.1460-2075.1993.tb05858.x",
      "article-title": "Integration of murine leukemia virus DNA depends on mitosis",
      "volume": "12",
      "author": "Roe",
      "year": "1993",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "1551",
      "DOI": "10.1002/j.1460-2075.1990.tb08274.x",
      "article-title": "HIV-1 replication is controlled at the level of T cell activation and proviral integration",
      "volume": "9",
      "author": "Stevenson",
      "year": "1990",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "193",
      "DOI": "10.1006/viro.1997.8606",
      "article-title": "Indicator cell lines for detection of primary strains of human and simian immunodeficiency viruses",
      "volume": "233",
      "author": "Vodicka",
      "year": "1997",
      "journal-title": "Virology"
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "175",
      "DOI": "10.1101/gad.12.2.175",
      "article-title": "HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection",
      "volume": "12",
      "author": "Vodicka",
      "year": "1998",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "1477",
      "DOI": "10.1084/jem.174.6.1477",
      "article-title": "Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes",
      "volume": "174",
      "author": "Weinberg",
      "year": "1991",
      "journal-title": "J. Exp. Med."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "376",
      "DOI": "10.1128/JVI.69.1.376-386.1995",
      "article-title": "Human immunodeficiency virus type 1 integrase",
      "volume": "69",
      "author": "Wiskerchen",
      "year": "1995",
      "journal-title": "J. Virol."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB50",
      "doi-asserted-by": "crossref",
      "first-page": "5113",
      "DOI": "10.1093/emboj/16.16.5113",
      "article-title": "Functional RT and IN incorporated into HIV-1 particles independently of the Gag/Pol precursor protein",
      "volume": "16",
      "author": "Wu",
      "year": "1997",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S1097-2765(01)00240-4_BIB51",
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      "first-page": "173",
      "DOI": "10.1016/S0092-8674(00)80828-4",
      "article-title": "HIV-1 genome nuclear import is mediated by a central DNA flap",
      "volume": "101",
      "author": "Zennou",
      "year": "2000",
      "journal-title": "Cell"
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