DOI: 10.1016/s1097-2765(01)00191-5. The Class II Phosphoinositide 3-Kinase C2α Is Activated by Clathrin and Regulates Clathrin-Mediated Membrane Trafficking

The Class II Phosphoinositide 3-Kinase C2α Is Activated by Clathrin and Regulates Clathrin-Mediated Membrane Trafficking

10.1016/s1097-2765(01)00191-5

Crossref journal-article

Elsevier BV

Molecular Cell (78)

Bibliography

Gaidarov, I., Smith, M. E. K., Domin, J., & Keen, J. H. (2001). The Class II Phosphoinositide 3-Kinase C2Î± Is Activated by Clathrin and Regulates Clathrin-Mediated Membrane Trafficking. Molecular Cell, 7(2), 443â449.

Authors 4

Ibragim Gaidarov (first)
Mary E.K Smith (additional)
Jan Domin (additional)
James H Keen (additional)

References 49 Referenced 195

10.1128/MCB.20.11.3817-3830.2000 / Mol. Cell. Biol. / Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors by Arcaro (2000)
10.1046/j.1471-4159.1995.65041636.x / J. Neurochem. / Phosphorylation and agonist-specific intracellular trafficking of an epitope-tagged mu-opioid receptor expressed in HEK 293 cells by Arden (1995)
10.1074/jbc.273.6.3791 / J. Biol. Chem. / Synergistic activation of dynamin GTPase by Grb2 and phosphoinositides by Barylko (1998)
10.1016/S0021-9258(20)64342-3 / J. Biol. Chem. / Interaction of phosphoinositide cycle intermediates with the plasma membrane-associated clathrin assembly protein AP-2 by Beck (1991)
10.1093/genetics/154.1.83 / Genetics / Synthetic genetic interactions with temperature-sensitive clathrin in Saccharomyces cerevisiae by Bensen (2000)
10.1016/S0955-0674(99)80066-0 / Curr. Opin. Cell Biol. / Phosphoinositides in membrane traffic by Corvera (1999)
10.1016/S0092-8674(00)81649-9 / Cell / Essential role of phosphoinositide metabolism in synaptic vesicle recycling by Cremona (1999)
10.1093/emboj/16.5.917 / EMBO J. / AP-3 by Dell'Angelica (1997)
10.1126/science.280.5362.431 / Science / Association of the AP-3 adaptor complex with clathrin by Dell'Angelica (1998)
10.1042/bj3260139 / Biochem. J. / Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin by Domin (1997)
10.1074/jbc.275.16.11943 / J. Biol. Chem. / The class II phosphoinositide 3-kinase PI3K–C2 is concentrated in the trans-Golgi network and present in clathrin-coated vesicles by Domin (2000)
10.1074/jbc.275.9.6479 / J. Biol. Chem. / Epsin binds to clathrin by associating directly with the clathrin-terminal domain. Evidence for cooperative binding through two discrete sites by Drake (2000)
10.1146/annurev.biochem.67.1.481 / Annu. Rev. Biochem. / Phosphoinositide kinases by Fruman (1998)
10.1074/jbc.272.39.24170 / J. Biol. Chem. / Inhibition of calcium-independent mannose 6-phosphate receptor incorporation into trans-Golgi network-derived clathrin-coated vesicles by wortmannin by Gaffet (1997)
10.1083/jcb.146.4.755 / J. Cell Biol. / Phosphoinositide-AP-2 interactions required for targeting to plasma membrane clathrin-coated pits by Gaidarov (1999)
10.1074/jbc.271.34.20922 / J. Biol. Chem. / A functional phosphatidylinositol 3,4,5-trisphosphate/phosphoinositide binding domain in the clathrin adaptor AP-2 subunit. Implications for the endocytic pathway by Gaidarov (1996)
10.1093/emboj/18.4.871 / EMBO J. / Arrestin function in G protein-coupled receptor endocytosis requires phosphoinositide binding by Gaidarov (1999)
10.1038/8971 / Nat. Cell Biol. / Spatial control of coated-pit dynamics in living cells by Gaidarov (1999)
10.1074/jbc.272.23.15017 / J. Biol. Chem. / Arrestin/clathrin interaction. Localization of the arrestin binding locus to the clathrin terminal domain by Goodman (1997)
10.1074/jbc.272.10.6393 / J. Biol. Chem. / Regulation of AP-3 function by inositides. Identification of phosphatidylinositol 3,4,5-trisphosphate as a potent ligand by Hao (1997)
10.1074/jbc.270.22.13225 / J. Biol. Chem. / Phosphatidylinositol 3-kinase activity is required at a postendocytic step in platelet-derived growth factor receptor trafficking by Joly (1995)
10.1016/S0960-9822(98)00022-0 / Curr. Biol. / Phosphatidylinositol-4,5-bisphosphate is required for endocytic coated vesicle formation by Jost (1998)
10.1083/jcb.105.5.1989 / J. Cell Biol. / Clathrin assembly proteins by Keen (1987)
10.1074/jbc.272.23.15011 / J. Biol. Chem. / Arrestin/clathrin interaction. Localization of the clathrin binding domain of nonvisual arrestins to the carboxy terminus by Krupnick (1997)
10.1016/S0960-9822(99)80115-8 / Curr. Biol. / Dominant-negative inhibition of receptor-mediated endocytosis by a dynamin-1 mutant with a defective pleckstrin homology domain by Lee (1999)
10.1083/jcb.140.5.1023 / J. Cell Biol. / A dominant-negative clathrin mutant differentially affects trafficking of molecules with distinct sorting motifs in the class II major histocompatibility complex (MHC) pathway by Liu (1998)
10.1016/S0960-9822(95)00278-8 / Curr. Biol. / A family of phosphoinositide 3-kinases in Drosophila identifies a new mediator of signal transduction by MacDougall (1995)
10.1074/jbc.271.18.10953 / J. Biol. Chem. / Wortmannin-sensitive trafficking pathways in Chinese hamster ovary cells. Differential effects on endocytosis and lysosomal sorting by Martys (1996)
10.1038/379353a0 / Nature / A presynaptic inositol-5-phosphatase by McPherson (1996)
10.1074/jbc.271.23.13892 / J. Biol. Chem. / Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain by Molz (1996)
10.1152/physrev.1997.77.3.759 / Physiol. Rev. / Endocytosis by Mukherjee (1997)
10.1006/bbrc.1994.2770 / Biochem. Biophys. Res. Commun. / Synaptotagmin is an inositol polyphosphate binding protein by Niinobe (1994)
10.1083/jcb.150.5.F111 / J. Cell Biol. / Molecular links between endocytosis and the actin cytoskeleton by Qualmann (2000)
10.1093/emboj/16.9.2240 / EMBO J. / Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes by Rapoport (1997)
10.1074/jbc.274.48.33959 / J. Biol. Chem. / The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module by Rosenthal (1999)
10.1016/S0021-9258(20)80560-2 / J. Biol. Chem. / Phosphorylation of the cytoplasmic tail of the 300-kDa mannose 6-phosphate receptor is required for the interaction with a cytosolic protein by Rosorius (1993)
10.1073/pnas.93.23.13327 / Proc. Natl. Acad. Sci. USA / Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin by Schiavo (1996)
10.1074/jbc.270.52.31083 / J. Biol. Chem. / A clathrin-binding site in the hinge of the beta 2 chain of mammalian AP-2 complexes by Shih (1995)
10.1074/jbc.M910430199 / J. Biol. Chem. / Tandem arrangement of the clathrin and AP-2 binding domains in amphiphysin 1 and disruption of clathrin coat function by amphiphysin fragments comprising these sites by Slepnev (2000)
10.1091/mbc.7.3.355 / Mol. Biol. Cell / Wortmannin alters the transferrin receptor endocytic pathway in vivo and in vitro by Spiro (1996)
10.1074/jbc.273.40.25987 / J. Biol. Chem. / The CC chemokine monocyte chemotactic peptide-1 activates both the class I p85/p110 phosphatidylinositol 3-kinase and the class II PI3K–C2 by Turner (1998)
10.1016/S0960-9822(99)80114-6 / Curr. Biol. / Importance of the pleckstrin homology domain of dynamin in clathrin-mediated endocytosis by Vallis (1999)
10.1006/excr.1999.4701 / Exp. Cell Res. / Signaling by distinct classes of phosphoinositide 3-kinases by Vanhaesebroeck (1999)
10.1074/jbc.271.23.13304 / J. Biol. Chem. / Mouse p170 is a novel phosphatidylinositol 3-kinase containing a C2 domain by Virbasius (1996)
10.1083/jcb.138.6.1239 / J. Cell Biol. / The role of ADP-ribosylation factor and phospholipase D in adaptor recruitment by West (1997)
10.1016/0014-4827(81)90108-7 / Exp. Cell Res. / Ultrastructural immunocytochemical localization of clathrin in cultured fibroblasts by Willingham (1981)
10.1016/S0021-9258(17)31499-0 / J. Biol. Chem. / Biochemical characterization of the free catalytic p110α and the complexed heterodimeric p110α-p85α forms of the mammalian phosphatidylinositol 3-kinase by Woscholski (1994)
10.1074/jbc.272.15.9625 / J. Biol. Chem. / Synaptojanin is the major constitutively active phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase in rodent brain by Woscholski (1997)
10.1006/jmbi.1996.0002 / J. Mol. Biol. / Identification of the binding site for acidic phospholipids on the pH domain of dynamin by Zheng (1996)

Dates

Type	When
Created	21 years, 4 months ago (April 15, 2004, 5:36 a.m.)
Deposited	4 years, 2 months ago (June 15, 2021, 12:26 p.m.)
Indexed	1 month, 3 weeks ago (July 7, 2025, 2:27 a.m.)
Issued	24 years, 6 months ago (Feb. 1, 2001)
Published	24 years, 6 months ago (Feb. 1, 2001)
Published Print	24 years, 6 months ago (Feb. 1, 2001)

Funders 0

None

BibTeX

@article{Gaidarov_2001, title={The Class II Phosphoinositide 3-Kinase C2α Is Activated by Clathrin and Regulates Clathrin-Mediated Membrane Trafficking}, volume={7}, ISSN={1097-2765}, url={http://dx.doi.org/10.1016/s1097-2765(01)00191-5}, DOI={10.1016/s1097-2765(01)00191-5}, number={2}, journal={Molecular Cell}, publisher={Elsevier BV}, author={Gaidarov, Ibragim and Smith, Mary E.K and Domin, Jan and Keen, James H}, year={2001}, month=feb, pages={443–449} }

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      "volume": "266",
      "author": "Beck",
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      "article-title": "Phosphoinositides in membrane traffic",
      "volume": "11",
      "author": "Corvera",
      "year": "1999",
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      "article-title": "Essential role of phosphoinositide metabolism in synaptic vesicle recycling",
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      "author": "Cremona",
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      "author": "Dell'Angelica",
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      "key": "10.1016/S1097-2765(01)00191-5_BIB9",
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      "volume": "326",
      "author": "Domin",
      "year": "1997",
      "journal-title": "Biochem. J."
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      "author": "Domin",
      "year": "2000",
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      "author": "Gaidarov",
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      "author": "Jost",
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      "article-title": "Clathrin assembly proteins",
      "volume": "105",
      "author": "Keen",
      "year": "1987",
      "journal-title": "J. Cell Biol."
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      "author": "Krupnick",
      "year": "1997",
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      "author": "Liu",
      "year": "1998",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "1404",
      "DOI": "10.1016/S0960-9822(95)00278-8",
      "article-title": "A family of phosphoinositide 3-kinases in Drosophila identifies a new mediator of signal transduction",
      "volume": "5",
      "author": "MacDougall",
      "year": "1995",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "10953",
      "DOI": "10.1074/jbc.271.18.10953",
      "article-title": "Wortmannin-sensitive trafficking pathways in Chinese hamster ovary cells. Differential effects on endocytosis and lysosomal sorting",
      "volume": "271",
      "author": "Martys",
      "year": "1996",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "353",
      "DOI": "10.1038/379353a0",
      "article-title": "A presynaptic inositol-5-phosphatase",
      "volume": "379",
      "author": "McPherson",
      "year": "1996",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "13892",
      "DOI": "10.1074/jbc.271.23.13892",
      "article-title": "Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain",
      "volume": "271",
      "author": "Molz",
      "year": "1996",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "759",
      "DOI": "10.1152/physrev.1997.77.3.759",
      "article-title": "Endocytosis",
      "volume": "77",
      "author": "Mukherjee",
      "year": "1997",
      "journal-title": "Physiol. Rev."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "1036",
      "DOI": "10.1006/bbrc.1994.2770",
      "article-title": "Synaptotagmin is an inositol polyphosphate binding protein",
      "volume": "205",
      "author": "Niinobe",
      "year": "1994",
      "journal-title": "Biochem. Biophys. Res. Commun."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "F111",
      "DOI": "10.1083/jcb.150.5.F111",
      "article-title": "Molecular links between endocytosis and the actin cytoskeleton",
      "volume": "150",
      "author": "Qualmann",
      "year": "2000",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "2240",
      "DOI": "10.1093/emboj/16.9.2240",
      "article-title": "Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes",
      "volume": "16",
      "author": "Rapoport",
      "year": "1997",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "33959",
      "DOI": "10.1074/jbc.274.48.33959",
      "article-title": "The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module",
      "volume": "274",
      "author": "Rosenthal",
      "year": "1999",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "21470",
      "DOI": "10.1016/S0021-9258(20)80560-2",
      "article-title": "Phosphorylation of the cytoplasmic tail of the 300-kDa mannose 6-phosphate receptor is required for the interaction with a cytosolic protein",
      "volume": "268",
      "author": "Rosorius",
      "year": "1993",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "13327",
      "DOI": "10.1073/pnas.93.23.13327",
      "article-title": "Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin",
      "volume": "93",
      "author": "Schiavo",
      "year": "1996",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "31083",
      "DOI": "10.1074/jbc.270.52.31083",
      "article-title": "A clathrin-binding site in the hinge of the beta 2 chain of mammalian AP-2 complexes",
      "volume": "270",
      "author": "Shih",
      "year": "1995",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "17583",
      "DOI": "10.1074/jbc.M910430199",
      "article-title": "Tandem arrangement of the clathrin and AP-2 binding domains in amphiphysin 1 and disruption of clathrin coat function by amphiphysin fragments comprising these sites",
      "volume": "275",
      "author": "Slepnev",
      "year": "2000",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "355",
      "DOI": "10.1091/mbc.7.3.355",
      "article-title": "Wortmannin alters the transferrin receptor endocytic pathway in vivo and in vitro",
      "volume": "7",
      "author": "Spiro",
      "year": "1996",
      "journal-title": "Mol. Biol. Cell"
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "25987",
      "DOI": "10.1074/jbc.273.40.25987",
      "article-title": "The CC chemokine monocyte chemotactic peptide-1 activates both the class I p85/p110 phosphatidylinositol 3-kinase and the class II PI3K\u2013C2",
      "volume": "273",
      "author": "Turner",
      "year": "1998",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "257",
      "DOI": "10.1016/S0960-9822(99)80114-6",
      "article-title": "Importance of the pleckstrin homology domain of dynamin in clathrin-mediated endocytosis",
      "volume": "9",
      "author": "Vallis",
      "year": "1999",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "239",
      "DOI": "10.1006/excr.1999.4701",
      "article-title": "Signaling by distinct classes of phosphoinositide 3-kinases",
      "volume": "253",
      "author": "Vanhaesebroeck",
      "year": "1999",
      "journal-title": "Exp. Cell Res."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "13304",
      "DOI": "10.1074/jbc.271.23.13304",
      "article-title": "Mouse p170 is a novel phosphatidylinositol 3-kinase containing a C2 domain",
      "volume": "271",
      "author": "Virbasius",
      "year": "1996",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "1239",
      "DOI": "10.1083/jcb.138.6.1239",
      "article-title": "The role of ADP-ribosylation factor and phospholipase D in adaptor recruitment",
      "volume": "138",
      "author": "West",
      "year": "1997",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "329",
      "DOI": "10.1016/0014-4827(81)90108-7",
      "article-title": "Ultrastructural immunocytochemical localization of clathrin in cultured fibroblasts",
      "volume": "132",
      "author": "Willingham",
      "year": "1981",
      "journal-title": "Exp. Cell Res."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "25067",
      "DOI": "10.1016/S0021-9258(17)31499-0",
      "article-title": "Biochemical characterization of the free catalytic p110\u03b1 and the complexed heterodimeric p110\u03b1-p85\u03b1 forms of the mammalian phosphatidylinositol 3-kinase",
      "volume": "269",
      "author": "Woscholski",
      "year": "1994",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S1097-2765(01)00191-5_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "9625",
      "DOI": "10.1074/jbc.272.15.9625",
      "article-title": "Synaptojanin is the major constitutively active phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase in rodent brain",
      "volume": "272",
      "author": "Woscholski",
      "year": "1997",
      "journal-title": "J. Biol. Chem."
    },
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      "first-page": "14",
      "DOI": "10.1006/jmbi.1996.0002",
      "article-title": "Identification of the binding site for acidic phospholipids on the pH domain of dynamin",
      "volume": "255",
      "author": "Zheng",
      "year": "1996",
      "journal-title": "J. Mol. Biol."
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