References
45
Referenced
175
10.1016/S0092-8674(00)80047-1
/ Cell / SOCS1 is a critical inhibitor of interferon γ signaling and prevents the potentially fatal neonatal actions of this cytokine by Alexander (1999)10.4049/jimmunol.167.4.2361
/ J. Immunol. / Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus by Arce (2001)10.1084/jem.20020619
/ J. Exp. Med. / A point mutation of Tyr-759 in interleukin 6 family cytokine receptor subunit gp130 causes autoimmune arthritis by Atsumi (2002)10.1172/JCI750
/ J. Clin. Invest. / Interferon-γ is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice by Balomenos (1998)10.1126/science.1064890
/ Science / Induction of dendritic cell differentiation by IFN-α in systemic lupus erythematosus by Blanco (2001)10.1038/11360
/ Nat. Med. / Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon by Cella (1999)10.1111/j.1600-065X.1999.tb01310.x
/ Immunol. Rev. / The central and multiple roles of B cells in lupus pathogenesis by Chan (1999)10.1016/S1074-7613(03)00078-5
/ Immunity / Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8+ T cell differentiation by Chong (2003)10.1111/j.1749-6632.1988.tb27079.x
/ Ann. N Y Acad. Sci. / B-cell compartment in the thymus of patients with myasthenia gravis and control subjects by Christensson (1988)10.4049/jimmunol.165.4.1799
/ J. Immunol. / Defective thymocyte development and perturbed homeostasis of T cells in STAT-induced STAT inhibitor-1/suppressors of cytokine signaling-1 transgenic mice by Fujimoto (2000)10.1038/ni825
/ Nat. Immunol. / PI3K-mediated negative feedback regulation of IL-12 production in DCs by Fukao (2002){'key': '10.1016/S1074-7613(03)00240-1_BIB12', 'first-page': '1621', 'article-title': 'Induction of systemic lupus erythematosus by interferon-γ in a patient with rheumatoid arthritis', 'volume': '18', 'author': 'Graninger', 'year': '1991', 'journal-title': 'J. Rheumatol.'}
/ J. Rheumatol. / Induction of systemic lupus erythematosus by interferon-γ in a patient with rheumatoid arthritis by Graninger (1991)10.1038/35010115
/ Nature / TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease by Gross (2000)10.4049/jimmunol.160.8.3713
/ J. Immunol. / IFN-γ receptor deletion prevents autoantibody production and glomerulonephritis in lupus-prone (NZB x NZW)F1 mice by Haas (1998)10.1074/jbc.M106139200
/ J. Biol. Chem. / A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box by Hanada (2001)10.1084/jem.193.12.1393
/ J. Exp. Med. / Aberrant high expression of B lymphocyte chemokine (BLC/CXCL13) by C11b+CD11c+ dendritic cells in murine lupus and preferential chemotaxis of B1 cells towards BLC by Ishikawa (2001)10.1016/S1074-7613(02)00425-9
/ Immunity / BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-κB2 by Kayagaki (2002)10.1016/S1074-7613(02)00446-6
/ Immunity / SOCS1/JAB is a negative regulator of LPS-induced macrophage activation by Kinjyo (2002)10.1038/ni829
/ Nat. Immunol. / DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL by Litinskiy (2002)10.1016/S0022-1759(98)00204-X
/ J. Immunol. Methods / An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow by Lutz (1999)10.1016/S1074-7613(02)00398-9
/ Immunity / Dendritic cells, BAFF, and APRIL by MacLennan (2002)10.1038/nri844
/ Nat. Rev. Immunol. / Baff by Mackay (2002)10.1046/j.1440-1711.2002.01115.x
/ Immunol. Cell Biol. / Immature, but not inactive by Mahnke (2002)10.1016/S0092-8674(00)80048-3
/ Cell / SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality by Marine (1999)10.1073/pnas.022628499
/ Proc. Natl. Acad. Sci. USA / Polycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1) by Metcalf (2002)10.1038/416865a
/ Nature / Increased proliferation of B cells and auto-immunity in mice lacking protein kinase C-delta by Miyamoto (2002)10.1126/science.285.5425.260
/ Science / Blys by Moore (1999)10.1016/S0304-3835(02)00244-6
/ Cancer Lett. / Combined hypermethylation and chromosome loss associated with inactivation of SSI-1/SOCS-1/JAB gene in human hepatocellular carcinomas by Nagai (2002)10.1016/S1074-7613(01)00132-7
/ Immunity / SOCS-1/SSI-1-deficient NKT cells participate in severe hepatitis through dysregulated cross-talk inhibition of IFN-γ and IL-4 signaling in vivo by Naka (2001)10.1016/S1074-7613(02)00449-1
/ Immunity / SOCS-1 participates in negative regulation of LPS responses by Nakagawa (2002)10.4049/jimmunol.165.10.5970
/ J. Immunol. / Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus by Odendahl (2000)10.1046/j.1440-1711.2002.01112.x
/ Immunol. Cell Biol. / The interplay of dendritic cell subsets in systemic lupus erythematosus by Palucka (2002)10.1172/JCI119361
/ J. Clin. Invest. / Roles of interferon-γ and interleukin-4 in murine lupus by Peng (1997)10.1111/j.1365-2796.1990.tb00144.x
/ J. Intern. Med. / Possible induction of systemic lupus erythematosus by interferon-α treatment in a patient with a malignant carcinoid tumour by Ronnblom (1990)10.1084/jem.183.6.2675
/ J. Exp. Med. / Protection against lethal toxic shock by targeted disruption of the CD28 gene by Saha (1996)10.1182/blood.V92.5.1668
/ Blood / A Janus kinase inhibitor, JAB, is an interferon-γ-inducible gene and confers resistance to interferons by Sakamoto (1998)10.4049/jimmunol.161.1.494
/ J. Immunol. / IFN-γ receptor signaling is essential for the initiation, acceleration, and destruction of autoimmune kidney disease in MRL-Fas(lpr) mice by Schwarting (1998)10.1084/jem.186.9.1451
/ J. Exp. Med. / Antinuclear autoantibodies and lupus nephritis in transgenic mice expressing interferon γ in the epidermis by Seery (1997)10.1172/JCI13568
/ J. Clin. Invest. / Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis by Shouda (2001)10.1126/science.284.5421.1835
/ Science / The nature of the principal type 1 interferon-producing cells in human blood by Siegal (1999)10.1073/pnas.231606698
/ Proc. Natl. Acad. Sci. USA / Avoiding horror autotoxicus by Steinman (2002)10.3109/10520299609117157
/ Biotech. Histochem. / Age associated changes in the distribution of lpr gene-induced B220-positive T cells in lymphoid organs of MRL/Mp-lpr/lpr mice using dual exposure microphotographs of double immunofluorescence staining by Usui (1996)10.1016/S1074-7613(01)00201-1
/ Immunity / Delineating the genetic basis of systemic lupus erythematosus by Wakeland (2001)10.1093/emboj/18.5.1309
/ EMBO J. / The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop by Yasukawa (1999)10.1038/ng0501-29
/ Nat. Genet. / SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity by Yoshikawa (2001)
Dates
Type | When |
---|---|
Created | 21 years, 4 months ago (April 15, 2004, 5:36 a.m.) |
Deposited | 2 years, 4 months ago (April 28, 2023, 4:02 a.m.) |
Indexed | 5 hours, 30 minutes ago (Sept. 6, 2025, 4:21 p.m.) |
Issued | 22 years ago (Sept. 1, 2003) |
Published | 22 years ago (Sept. 1, 2003) |
Published Print | 22 years ago (Sept. 1, 2003) |
Funders
5
Uehara Memorial Foundation
10.13039/100008732
Region: Asia
pri (Trusts, charities, foundations (both public and private))
Labels
4
- The Uehara Memorial Foundation
- Uehara Memorial Life Science Foundation
- 上原記念生命科学財団
- UMF
Human Frontier Science Program
10.13039/501100000854
Region: Europe
pri (International organizations)
Labels
1
- HFSP
Japan Health Sciences Foundation
10.13039/100007416
Region: Asia
pri (Trusts, charities, foundations (both public and private))
Labels
1
- JHSF
Japan Research Foundation for Clinical Pharmacology
10.13039/100008728
Ministry of Education, Culture, Sports, Science and Technology
10.13039/501100001700
Region: Asia
gov (National government)
Labels
3
- Monbu-kagaku-shō
- 文部科学省
- MEXT
@article{Hanada_2003, title={Suppressor of Cytokine Signaling-1 Is Essential for Suppressing Dendritic Cell Activation and Systemic Autoimmunity}, volume={19}, ISSN={1074-7613}, url={http://dx.doi.org/10.1016/s1074-7613(03)00240-1}, DOI={10.1016/s1074-7613(03)00240-1}, number={3}, journal={Immunity}, publisher={Elsevier BV}, author={Hanada, Toshikatsu and Yoshida, Hiroki and Kato, Seiya and Tanaka, Kentaro and Masutani, Kohsuke and Tsukada, Jun and Nomura, Yoshio and Mimata, Hiromitsu and Kubo, Masato and Yoshimura, Akihiko}, year={2003}, month=sep, pages={437–450} }