Crossref journal-article
Elsevier BV
Immunity (78)
Bibliography

Adachi, O., Kawai, T., Takeda, K., Matsumoto, M., Tsutsui, H., Sakagami, M., Nakanishi, K., & Akira, S. (1998). Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function. Immunity, 9(1), 143–150.

Authors 8
  1. Osamu Adachi (first)
  2. Taro Kawai (additional)
  3. Kiyoshi Takeda (additional)
  4. Makoto Matsumoto (additional)
  5. Hiroko Tsutsui (additional)
  6. Masafumi Sakagami (additional)
  7. Kenji Nakanishi (additional)
  8. Shizuo Akira (additional)
References 49 Referenced 1,695
  1. 10.4049/jimmunol.160.8.3642 / J. Immunol / IL-12 and IL-18 differentially regulate the transcriptional activity of the human IFN-γ promoter in primary CD4+ T lymphocytes by Barbulescu (1998)
  2. 10.1038/379591a0 / Nature / A newly defined interleukin-1? by Bazan (1996)
  3. 10.1146/annurev.cellbio.12.1.393 / Annu. Rev. Cell. Dev. Biol / A conserved signaling pathway by Belvin (1996)
  4. 10.1016/S0014-5793(96)01506-2 / FEBS Lett / The cloning and characterization of human MyD88 by Bonnert (1997)
  5. 10.1126/science.271.5252.1128 / Science / IRAK by Cao (1996)
  6. 10.1038/383443a0 / Nature / TRAF6 is a signal transducer for interleukin-1 by Cao (1996)
  7. 10.1016/S0065-2776(08)60642-2 / Adv. Immunol / Interleukin-1 and its biologically related cytokines by Dinarello (1989)
  8. 10.1182/blood.V87.6.2095.bloodjournal8762095 / Blood / Biologic basis for interleukin-1 in disease by Dinarello (1996)
  9. 10.1242/dev.121.7.2209 / Development / Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos by Galindo (1995)
  10. 10.1038/351355b0 / Nature / Drosophila Toll and IL-1 receptor by Gay (1991)
  11. 10.1038/386619a0 / Nature / Caspase-1 processes IFN-γ inducing factor and regulates LPS-induced IFN-γ production by Ghayur (1997)
  12. 10.1074/jbc.270.23.13757 / J. Biol. Chem / Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex by Greenfeder (1995)
  13. 10.1038/372563a0 / Nature / Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo by Grosshans (1994)
  14. 10.1126/science.275.5297.206 / Science / Activation of interferon-γ inducing factor mediated by interleukin-1β converting enzyme by Gu (1997)
  15. {'key': '10.1016/S1074-7613(00)80596-8_BIB15', 'first-page': '2467', 'article-title': 'Molecular characterization and molecular analysis of human MyD88', 'volume': '13', 'author': 'Hardiman', 'year': '1996', 'journal-title': 'Oncogene'} / Oncogene / Molecular characterization and molecular analysis of human MyD88 by Hardiman (1996)
  16. 10.1016/0092-8674(88)90516-8 / Cell / The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein by Hashimoto (1988)
  17. 10.1073/pnas.94.24.12829 / Proc. Natl. Acad. Sci. USA / Recruitment of IRAK to the interleukin-1 receptor complex requires interleukin-1 receptor accessory protein by Huang (1997)
  18. 10.1006/bbrc.1994.1206 / Biochem. Biophys. Res. Commun / Macrophage differentiation marker MyD88 is a member of the Toll/IL-1 receptor family by Hultmark (1994)
  19. 10.1002/eji.1830270139 / Eur. J. Immunol / A critical role for interleukin-1 receptor accessory protein in interleukin-1 signaling by Korherr (1997)
  20. 10.1016/S0092-8674(00)80172-5 / Cell / The dorsoventral regulatory gene cassette spatzle/toll/cactus controls the potent antifungal reponse in Drosophila adults by Lemaitre (1996)
  21. 10.1002/j.1460-2075.1993.tb06019.x / EMBO J / Domain mapping of tube, a protein essential for dorsoventral patterning of the Drosophila embryo by Letsou (1993)
  22. {'key': '10.1016/S1074-7613(00)80596-8_BIB22', 'first-page': '1095', 'article-title': 'Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL-6', 'volume': '5', 'author': 'Lord', 'year': '1990', 'journal-title': 'Oncogene'} / Oncogene / Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL-6 by Lord (1990)
  23. 10.1016/S0165-5728(96)00047-1 / J. Neuroimmunol / Cloning of a cDNA encoding a novel interleukin-1 receptor related protein (IL-1R-rp2) by Lovenberg (1996)
  24. 10.4049/jimmunol.134.5.3108 / J. Immunol / Induction of interleukin 2 responsiveness in thymocytes by synergistic action of interleukin 1 and interleukin 2 by Mannel (1985)
  25. 10.4049/jimmunol.159.1.97 / J. Immunol / Propionibacterium acnes treatment diminishes CD4+NK1.1+ T cells but induces type 1 T cells in the liver by induction of IL-12 and IL-18 production from Kupffer cells by Matsui (1997)
  26. 10.1006/bbrc.1997.6665 / Biochem. Biophys. Res. Commun / Interleukin-18 activates NF-κB in murine T helper type 1 cells by Matsumoto (1997)
  27. 10.1016/S0092-8674(00)80412-2 / Cell / Innate Immunity by Medzhitov (1997)
  28. 10.1038/41131 / Nature / A human homologue of the Drosophila Toll protein signals activation of adaptive immunity by Medzhitov (1997)
  29. 10.1074/jbc.271.10.5777 / J. Biol. Chem / T1/ST2 signaling establishes it as a member of an expanding interleukin-1 receptor family by Mitcham (1996)
  30. 10.1093/nar/18.17.5322 / Nucleic Acids Res / pEF-BOS, a powerful mammalian expression vector by Mizushima (1990)
  31. 10.1016/0092-8674(94)90507-X / Cell / The spatzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryo by Morisato (1994)
  32. 10.1146/annurev.ge.29.120195.002103 / Annu. Rev. Genet / Signaling pathways that establish the dorso-ventral pattern of the Drosophila embryo by Morisato (1995)
  33. 10.1126/science.278.5343.1612 / Science / IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling by Muzio (1997)
  34. 10.1101/gad.10.7.862 / Genes Dev / Functional interaction between the pelle kinase, Toll receptor, and tube suggest a mechanism for activation of dorsal by Norris (1996)
  35. 10.1128/iai.63.10.3966-3972.1995 / Infect. Immun / A novel costimulatory factor for gamma interferon induction found in the livers of mice causes endotoxin shock by Okamura (1995)
  36. 10.1038/378088a0 / Nature / Cloning of a new cytokine that induces IFN-γ production by T cells by Okamura (1995)
  37. 10.1074/jbc.271.8.3967 / J. Biol. Chem / IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP by Parnet (1996)
  38. 10.1016/S1074-7613(00)80378-7 / Immunity / IGIF does not drive Th1 development but synergizes with IL-12 for interferon-γ production and activates IRAK and NF-κB by Robinson (1997)
  39. 10.1073/pnas.95.2.588 / Proc. Natl. Acad. Sci. USA / A family of human receptors structurally related to Drosophila Toll by Rock (1998)
  40. 10.1016/0092-8674(93)90071-W / Cell / pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo by Shelton (1993)
  41. 10.1016/0022-1759(89)90239-1 / J. Immunol. Methods / Biological activity of recombinant murine interleukin 6 in interleukin 1 T cell assays by Suda (1989)
  42. 10.1016/S1074-7613(00)80543-9 / Immunity / Defective NK cell activity and Th1 response in IL-18-deficient mice by Takeda (1998)
  43. 10.1074/jbc.272.41.25737 / J. Biol. Chem / Purification and characterization of the human interrleukin-18 receptor by Torigoe (1997)
  44. 10.4049/jimmunol.157.9.3967 / J. Immunol / IFN-γ-inducing factor up-regulates Fas ligand-mediated cytotoxic activity of murine natural killer cell clones by Tsutsui (1996)
  45. 10.4049/jimmunol.156.11.4274 / J. Immunol / Cloning of the cDNA for human IFN-γ inducing factor, expression in Escherichia coli and studies on the biologic activities of the protein by Ushio (1996)
  46. 10.1091/mbc.4.8.767 / Mol. Biol. Cell / A conserved signal transduction pathway regulating the activity of the rel-like proteins dorsal and NF-κB by Wasserman (1993)
  47. 10.1074/jbc.272.12.7727 / J. Biol. Chem / The interleukin-1 receptor accessory protein (IL-1RAcP) is essential for IL-1-induced activatin of interleukin-1 receptor associated kinase (IRAK) and stress-activated protein kinases (SAP kinases) by Wesche (1997)
  48. 10.1016/S1074-7613(00)80402-1 / Immunity / MyD88 by Wesche (1997)
  49. 10.1016/0014-5793(93)81333-U / FEBS Lett / Presence of a novel primary response gene ST2L, encoding a product highly similar to the interleukin 1 receptor type 1 by Yanagisawa (1993)
Dates
Type When
Created 21 years, 2 months ago (June 22, 2004, 9:29 a.m.)
Deposited 2 years, 3 months ago (April 28, 2023, 2:06 p.m.)
Indexed 2 days, 12 hours ago (Aug. 21, 2025, 12:36 p.m.)
Issued 27 years, 1 month ago (July 1, 1998)
Published 27 years, 1 month ago (July 1, 1998)
Published Print 27 years, 1 month ago (July 1, 1998)
Funders 0

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@article{Adachi_1998, title={Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function}, volume={9}, ISSN={1074-7613}, url={http://dx.doi.org/10.1016/s1074-7613(00)80596-8}, DOI={10.1016/s1074-7613(00)80596-8}, number={1}, journal={Immunity}, publisher={Elsevier BV}, author={Adachi, Osamu and Kawai, Taro and Takeda, Kiyoshi and Matsumoto, Makoto and Tsutsui, Hiroko and Sakagami, Masafumi and Nakanishi, Kenji and Akira, Shizuo}, year={1998}, month=jul, pages={143–150} }