DOI: 10.1016/s1074-7613(00)80422-7. Regulation of Vav–SLP-76 Binding by ZAP-70 and Its Relevance to TCRζ/CD3 Induction of Interleukin-2

Regulation of Vav–SLP-76 Binding by ZAP-70 and Its Relevance to TCRζ/CD3 Induction of Interleukin-2

10.1016/s1074-7613(00)80422-7

Crossref journal-article

Elsevier BV

Immunity (78)

Bibliography

Raab, M., Silva, A. J. da, Findell, P. R., & Rudd, C. E. (1997). Regulation of VavâSLP-76 Binding by ZAP-70 and Its Relevance to TCRÎ¶/CD3 Induction of Interleukin-2. Immunity, 6(2), 155â164.

Authors 4

Monika Raab (first)
Antonio J.da Silva (additional)
Paul R. Findell (additional)
Christopher E. Rudd (additional)

References 46 Referenced 189

10.1099/0022-1317-36-2-361 / J. Gen. Virol / A plaque assay for nuclear polyhedrosis viruses using a solid overlay by Brown (1977)
10.1074/jbc.271.33.19641 / J. Biol. Chem / Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T cell receptor function by Bubeck Wardenburg (1996)
10.1073/pnas.89.19.9311 / Proc. Natl. Acad. Sci. USA / CD5 acts as a tyrosine kinase substrate within a receptor complex comprising T-cell receptor ζ chain/CD3 and protein-tyrosine kinases p56lck and p59fyn by Burgess (1992)
10.1126/science.256.5060.1196 / Science / Tyrosine phosphorylation of the vav proto-oncogene product in activated B cells by Bustelo (1992)
{'key': '10.1016/S1074-7613(00)80422-7_BIB5', 'first-page': '2405', 'article-title': 'Vav cooperates with Ras to transform rodent fibroblasts but is not a Ras GDP/GTP exchange factor', 'volume': '9', 'author': 'Bustelo', 'year': '1994', 'journal-title': 'Oncogene'} / Oncogene / Vav cooperates with Ras to transform rodent fibroblasts but is not a Ras GDP/GTP exchange factor by Bustelo (1994)
10.1002/j.1460-2075.1995.tb07247.x / EMBO J / Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function by Chan (1995)
10.1084/jem.178.6.2107 / J. Exp. Med / TcRζ/CD3-p59fyn(T) associated p120/130 binds to the SH2 domain of p59fyn(T) by da Silva (1993)
10.4049/jimmunol.158.5.2007 / J. Immunol / Biochemical analysis of p120/p130 by da Silva (1997)
10.1016/S0021-9258(17)31595-8 / J. Biol. Chem / The protein product of the c-cbl protooncogene is the 120-kDa tyrosine-phosphorylated protein in Jurkat cells activated via the T cell antigen receptor by Donovan (1994)
10.1016/0092-8674(92)90444-H / Cell / Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways by Fantl (1992)
10.1038/374474a0 / Nature / Defective T-cell receptor signaling and positive selection of vav-deficient CD4+CD8+ thymocytes by Fischer (1995)
10.4049/jimmunol.120.6.2027 / J. Immunol / T cell growth factor by Gillis (1978)
{'key': '10.1016/S1074-7613(00)80422-7_BIB13', 'first-page': '3030', 'article-title': 'The proto-oncogene Vav product is constitutively tyrosine-phosphorylated in normal human immature T cells', 'volume': '25', 'author': 'Gouy', 'year': '1995', 'journal-title': 'J. Immunol'} / J. Immunol / The proto-oncogene Vav product is constitutively tyrosine-phosphorylated in normal human immature T cells by Gouy (1995)
10.1126/science.8484124 / Science / Tyrosine kinase-stimulated guanine nucleotide exchange activity of vav in T cell activation by Gulbins (1993)
10.1126/science.7509083 / Science / Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases by Iwashima (1994)
10.1074/jbc.270.13.7029 / J. Biol. Chem / Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells by Jackman (1995)
10.1002/j.1460-2075.1989.tb08354.x / EMBO J / Vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells by Katzav (1989)
10.1016/S0021-9258(18)31673-9 / J. Biol. Chem / The protein tyrosine kinase ZAP-70 can associate with the SH2 domain of proto-vav by Katzav (1994)
10.1128/MCB.14.10.6848 / Mol. Cell. Biol / Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras by Khosravi-Far (1994)
10.1126/science.1708916 / Science / SH2 and SH3 domains by Koch (1991)
10.1038/356071a0 / Nature / Tyrosine phosphorylation of vav by Margolis (1992)
10.1074/jbc.270.42.24949 / J. Biol. Chem / Distinct isoforms of the CD45 protein-tyrosine phosphatase differentially regulate interleukin 2 secretion and activation signal pathways involving Vav in T cells by McKenney (1995)
10.1084/jem.183.4.1937 / J. Exp. Med / Implication of the GRB-2 associated phosphoprotein SLP-76 in TCR-mediated IL-2 production by Motto (1996)
10.1016/1074-7613(94)90065-5 / Immunity / T cell antigen receptor signaling by Mustelin (1994)
10.1074/jbc.271.36.22225 / J. Biol. Chem / Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein tyrosine phosphatase by Onodera (1996)
10.1074/jbc.270.7.2897 / J. Biol. Chem / Potent stimulation of SH-PTP2 phosphatase activity by simultaneous occupancy of both SH2 domains by Pluskey (1995)
10.1073/pnas.91.7.2834 / Proc. Natl. Acad. Sci. USA / T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif by Prasad (1994)
10.1006/bbrc.1996.0696 / Biochem. Biophys. Res. Commun / Hematopoietic cell phosphatase (HCP) regulates p56lck phosphorylation and ZAP-70 binding to the T cell receptor ζ chain by Raab (1996)
10.1128/MCB.14.5.2862 / Mol. Cell. Biol / The T-cell antigen CD5 acts as a receptor and substrate for the protein-tyrosine kinase p56lck by Raab (1994)
10.1073/pnas.92.19.8891 / Proc. Natl. Acad. Sci. USA / p56lck and p59fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK by Raab (1995)
10.1126/science.8235613 / Science / Interaction of Shc with the ζ chain of the T cell receptor upon T cell activation by Ravichandran (1993)
10.1074/jbc.271.14.8435 / J. Biol. Chem / Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G by Reedquist (1996)
10.1073/pnas.88.23.10696 / Proc. Natl. Acad. Sci. USA / Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxyl terminus of pp60c-src by Roussel (1991)
10.1016/0167-5699(94)90248-8 / Immunol. Today / Two step TcRζ/CD3-CD4 and CD28 signalling in T-cells by Rudd (1994)
10.1016/S0021-9258(19)73981-7 / J. Biol. Chem / Tyrosine kinases and tyrosine-based activation motifs by Samelson (1992)
10.1038/374467a0 / Nature / Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav by Tarakhovsky (1995)
10.1016/S1074-7613(00)80315-5 / Immunity / Complex complexes by Wange (1996)
10.1016/S0021-9258(19)36584-6 / J. Biol. Chem / Tandem SH2 domains of ZAP-70 bind to T cell antigen receptor ζ and CD3ε from activated Jurkat T cells by Wange (1993)
10.1074/jbc.270.32.18730 / J. Biol. Chem / Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70 by Wange (1995)
10.1016/0092-8674(94)90334-4 / Cell / Signal transduction of lymphocyte antigen receptors by Weiss (1994)
10.1073/pnas.88.13.5484 / Proc. Natl. Acad. Sci. USA / Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-γ1 by Weiss (1991)
10.1016/S1074-7613(00)80485-9 / Immunity / Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation by Wu (1996)
10.1073/pnas.91.26.12629 / Proc. Natl. Acad. Sci. USA / Binding of Vav to Grb2 through dimerization of Src homology 3 domains by Ye (1994)
10.1016/1074-7613(95)90171-X / Immunity / Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation by Yun-Cai (1995)
10.1038/342278a0 / Nature / Inability of CD8α′ polypeptides to associate with p56lck correlates with impaired function in vitro and lack of expression in vivo by Zamoyska (1989)
10.1038/374470a0 / Nature / Defective signaling through the T and B cell antigen receptors in lymphoid cells lacking the vav proto-oncogne by Zhang (1995)

Dates

Type	When
Created	21 years, 2 months ago (June 22, 2004, 1:29 p.m.)
Deposited	8 months, 1 week ago (Dec. 17, 2024, 12:17 p.m.)
Indexed	1 week, 3 days ago (Aug. 19, 2025, 6:27 a.m.)
Issued	28 years, 6 months ago (Feb. 1, 1997)
Published	28 years, 6 months ago (Feb. 1, 1997)
Published Print	28 years, 6 months ago (Feb. 1, 1997)

Funders 0

None

BibTeX

@article{Raab_1997, title={Regulation of Vav–SLP-76 Binding by ZAP-70 and Its Relevance to TCRζ/CD3 Induction of Interleukin-2}, volume={6}, ISSN={1074-7613}, url={http://dx.doi.org/10.1016/s1074-7613(00)80422-7}, DOI={10.1016/s1074-7613(00)80422-7}, number={2}, journal={Immunity}, publisher={Elsevier BV}, author={Raab, Monika and Silva, Antonio J.da and Findell, Paul R. and Rudd, Christopher E.}, year={1997}, month=feb, pages={155–164} }

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      "article-title": "Hematopoietic cell phosphatase (HCP) regulates p56lck phosphorylation and ZAP-70 binding to the T cell receptor \u03b6 chain",
      "volume": "222",
      "author": "Raab",
      "year": "1996",
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      "volume": "14",
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      "year": "1994",
      "journal-title": "Mol. Cell. Biol"
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      "volume": "92",
      "author": "Raab",
      "year": "1995",
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      "volume": "262",
      "author": "Ravichandran",
      "year": "1993",
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      "volume": "271",
      "author": "Reedquist",
      "year": "1996",
      "journal-title": "J. Biol. Chem"
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      "volume": "88",
      "author": "Roussel",
      "year": "1991",
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      "volume": "15",
      "author": "Rudd",
      "year": "1994",
      "journal-title": "Immunol. Today"
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      "article-title": "Tyrosine kinases and tyrosine-based activation motifs",
      "volume": "267",
      "author": "Samelson",
      "year": "1992",
      "journal-title": "J. Biol. Chem"
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      "author": "Tarakhovsky",
      "year": "1995",
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      "author": "Wange",
      "year": "1996",
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      "volume": "268",
      "author": "Wange",
      "year": "1993",
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      "volume": "270",
      "author": "Wange",
      "year": "1995",
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      "author": "Weiss",
      "year": "1994",
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      "author": "Weiss",
      "year": "1991",
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      "author": "Wu",
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      "volume": "91",
      "author": "Ye",
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      "author": "Zamoyska",
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