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journal-article
Elsevier BV
Structure (78)
References
59
Referenced
365
10.1016/S0065-230X(08)60399-1
/ Adv. Cancer Res / MAP kinases ERK1 and ERK2: pleiotropic enzymes in a ubiquitous signaling network by Robbins (1994)10.1074/jbc.270.25.14843
/ J. Biol. Chem / How MAP kinases are regulated by Cobb (1995)10.1016/0014-5793(95)00357-F
/ FEBS Lett / SB203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1 by Cuenda (1995)10.1096/fasebj.9.9.7601337
/ FASEB J / The MAPK signaling cascade by Seger (1995)10.1074/jbc.271.50.31929
/ J. Biol. Chem / The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and γ radiation by Chen (1996)10.1016/S0968-0004(00)88978-1
/ Trends Biochem. Sci / Parallel signal processing among mammalian MAPKs by Cano (1995)10.1038/372739a0
/ Nature / A protein kinase involved in the regulation of inflammatory cytokine biosynthesis by Lee (1994)10.1172/JCI119309
/ J. Clin. Invest / Hyperexpression of mitogen-activated protein kinase in human breast cancer by Sivaraman (1997)10.1073/pnas.92.25.11746
/ Proc. Natl Acad. Sci. USA / The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation by Raitano (1995)10.1126/science.2164259
/ Science / An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control by Boulton (1990)10.1016/0092-8674(91)90098-J
/ Cell / ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF by Boulton (1991)10.1016/0092-8674(94)90380-8
/ Cell / JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain by Dérijard (1994)10.1038/369156a0
/ Nature / The stress-activated protein kinase subfamily of c-jun kinases by Kyriakis (1994)10.1101/gad.8.24.2996
/ Genes Dev / JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation by Kallunki (1994)10.1126/science.7914033
/ Science / A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells by Han (1994)10.1016/0092-8674(94)90277-1
/ Cell / A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins by Rouse (1994)10.1016/0092-8674(94)90278-X
/ Cell / Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27 by Freshney (1994)10.1016/0092-8674(93)90533-V
/ Cell / The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the MAP kinase pathway and induces cell proliferation by Sontag (1993)10.1074/jbc.270.13.7420
/ J. Biol. Chem / Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine by Raingeaud (1995)10.1074/jbc.271.40.24313
/ J. Biol. Chem / Sounding the alarm: Protein kinase cascades activated by stress and inflammation by Kyriakis (1996)10.1126/science.274.5290.1194
/ Science / Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors by Rosette (1996)10.1016/0958-1669(95)80108-1
/ Curr. Opin Biotechnol / Inhibitors of serine/threonine kinases by Lee (1995)10.1016/S0968-0896(96)00212-X
/ Bioorg. Med. Chem. Lett / Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase by Gallagher (1997){'key': '10.1016/S0969-2126(98)00113-0_BIB24', 'first-page': '1453', 'article-title': 'Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function', 'volume': '279', 'author': 'Badger', 'year': '1996', 'journal-title': 'J. Pharmacol. Exp. Ther'}
/ J. Pharmacol. Exp. Ther / Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function by Badger (1996)10.1074/jbc.272.18.12116
/ J. Biol. Chem / Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site by Young (1997)10.1038/nsb0497-311
/ Nat. Struct. Biol / A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket by Tong (1997)10.1016/S1074-5521(97)90194-0
/ Chem. Biol / The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase by Wilson (1997)10.1038/367704a0
/ Nature / Atomic structure of the MAP kinase ERK2 at 2.3 å resolution by Zhang (1994)10.1073/pnas.94.6.2327
/ Proc. Natl Acad. Sci. USA / The structure of the mitogen-activated protein kinase P38 at 2.1 resolution by Wang (1997)10.1074/jbc.271.44.27696
/ J. Biol. Chem / Crystal structure of the p38 mitogen-activated protein kinase by Wilson (1996)10.1016/S0092-8674(00)80351-7
/ Cell / Activation mechanism of the MAP kinase ERK2 by dual phosphorylation by Canagarajah (1997)10.1016/0959-440X(94)90264-X
/ Curr. Opin. Struct. Biol / Protein kinases by Goldsmith (1994){'key': '10.1016/S0969-2126(98)00113-0_BIB33', 'first-page': '771', 'article-title': 'Inhibition of cyclin-dependent kinases by purine analogues. Eur', 'volume': '224', 'author': 'Vesely', 'year': '1994', 'journal-title': 'J. Biochem'}
/ J. Biochem / Inhibition of cyclin-dependent kinases by purine analogues. Eur by Vesely (1994)10.1016/S0021-9258(18)45614-1
/ J. Biol. Chem / Genistein, a specific inhibitor of tyrosine-specific protein kinases by Akiyama (1987)10.1111/j.1432-1033.1983.tb07692.x
/ Eur. J. Biochem / The effect of quercetin on the phosphorylation activity of the Rous sarcoma virus transforming gene product in vitro and in vivo by Graziani (1983)10.1074/jbc.270.46.27489
/ J. Biol. Chem / PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinases kinase in vitro and in vivo by Alessi (1995)10.1126/science.1862342
/ Science / Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase by Knighton (1991)10.1038/363595a0
/ Nature / Crystal structure of cyclin-dependent kinase 2 by De Bondt (1993)10.1002/prot.340220408
/ Proteins / Multiple modes of ligand recognition: Crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine by Schulze-Gahmen (1995)10.1126/science.276.5314.955
/ Science / Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors by Mohammadi (1997)10.1021/jm960380s
/ J. Med. Chem / Structure-based design of a potent selective, and irreversible inhibitor of the catalytic domain of the erbB receptor subfamily of protein tyrosine kinases by Singh (1997)10.1073/pnas.93.7.2735
/ Proc. Natl Acad. Sci. USA / Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase by De Azevedo (1996)10.1016/0079-6107(84)90007-5
/ Prog. Biophys. Mol. Biol / Hydroden bonding in globular proteins by Baker (1984)10.1111/j.1432-1033.1997.0518a.x
/ Eur. J. Biochem / Inhibition of cyclin-dependent kinases by purine analogues - Crystal structure of human cdk2 complexed with roscovitine by De Azevedo (1997)10.1073/pnas.93.13.6308
/ Proc. Natl Acad. Sci. USA / Structural basis for selectivity of the isoquinoline sulfonamide family of protein kinase inhibitors by Xu (1996)10.1016/0014-5793(96)00255-4
/ FEBS Lett / SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases by Mertens (1996)10.1006/bbrc.1997.6849
/ Biochem. Biophys. Res. Commun / Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles by Kumar (1997)10.1093/emboj/16.12.3563
/ EMBO J / Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases by Goedert (1997)10.1074/jbc.273.25.15605
/ J. Biol. Chem / Acquistion of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB203580, by alteration of one or more amino acids within the ATP binding pocket by Gum (1998)10.1016/0968-0004(94)90022-1
/ Trends. Biochem. Sci / The glycine-rich sequence of protein kinases: a multifunctional element by Bossemeyer (1994)10.1016/S0092-8674(00)81092-2
/ Cell / Active and inactive protein kinases: Structural basis for regulation by Johnson (1996){'key': '10.1016/S0969-2126(98)00113-0_BIB52', 'series-title': 'Proceedings of the CCP4 Study Weekend: Data Collection and Processing', 'first-page': '56', 'article-title': 'Oscillation data reduction program', 'author': 'Otwinowski', 'year': '1993'}
/ Proceedings of the CCP4 Study Weekend: Data Collection and Processing / Oscillation data reduction program by Otwinowski (1993)10.1107/S0108767386099622
/ Acta Cryst. A / Improved fourier coefficients for maps using phases from partial structures with errors by Read (1986)10.1107/S0907444994003112
/ Acta Cryst. D / The CCP4 suite: programs for protein crystallography (1994){'key': '10.1016/S0969-2126(98)00113-0_BIB55', 'series-title': 'O version 5.9', 'author': 'Jones', 'year': '1993'}
/ O version 5.9 by Jones (1993){'key': '10.1016/S0969-2126(98)00113-0_BIB56', 'series-title': 'X-PLOR Version 3.1: A System for X-ray Crystallography and NMR', 'author': 'Brünger', 'year': '1992'}
/ X-PLOR Version 3.1: A System for X-ray Crystallography and NMR by Brünger (1992)10.1107/S0021889892009944
/ J. Appl. Cryst / Procheck: a program to check the stereochemical quality of protein structures by Laskowski (1993)10.1016/0263-7855(93)87009-T
/ J. Mol. Graph / SETOR: Hardware lighted three-dimensional solid model representations of macromolecules by Evans (1993){'key': '10.1016/S0969-2126(98)00113-0_BIB59', 'first-page': '133', 'article-title': 'An extensively modified version of Molscript that includes greatly enhanced coloring capabilities', 'volume': '15', 'author': 'Esnousf', 'year': '1997', 'journal-title': 'J. Mol. Graph'}
/ J. Mol. Graph / An extensively modified version of Molscript that includes greatly enhanced coloring capabilities by Esnousf (1997)
@article{Wang_1998, title={Structural basis of inhibitor selectivity in MAP kinases}, volume={6}, ISSN={0969-2126}, url={http://dx.doi.org/10.1016/s0969-2126(98)00113-0}, DOI={10.1016/s0969-2126(98)00113-0}, number={9}, journal={Structure}, publisher={Elsevier BV}, author={Wang, Zhulun and Canagarajah, Bertram J and Boehm, Jeffrey C and Kassisà, Skouki and Cobb, Melanie H and Young, Peter R and Abdel-Meguid, Sherin and Adams, Jerry L and Goldsmith, Elizabeth J}, year={1998}, month=sep, pages={1117–1128} }