DOI: 10.1016/s0969-2126(94)00076-x. Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5å resolution

Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5å resolution

10.1016/s0969-2126(94)00076-x

Crossref journal-article

Elsevier BV

Structure (78)

Bibliography

Bodian, D. L., Jones, E. Y., Harlos, K., Stuart, D. I., & Davis, S. J. (1994). Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5Ã¥ resolution. Structure, 2(8), 755â766.

Authors 5

Dale L Bodian (first)
E.Yvonne Jones (additional)
Karl Harlos (additional)
David I Stuart (additional)
Simon J Davis (additional)

References 55 Referenced 125

{'key': '10.1016/S0969-2126(94)00076-X_BIB1', 'series-title': 'The Leucocyte Antigen Facts Book', 'author': 'Barclay', 'year': '1993'} / The Leucocyte Antigen Facts Book by Barclay (1993)
10.1084/jem.179.1.341 / J Exp. Med / Anti-CD2 receptor and anti-CD2 ligand (CD48) antibodies synergize to prolong allograft survival by Qin (1994)
10.1084/jem.165.3.677 / J. Exp. Med / Purified lymphocyte function-associated antigen 3 binds to CD2 and mediates T lymphocyte adhesion by Dustin (1987)
10.1038/326400a0 / Nature / The T lymphocyte glycoprotein CD2 binds the cell surface ligand LFA-3 by Selvaraj (1987)
10.1084/jem.176.5.1241 / J. Exp. Med / CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation by Kato (1992)
10.1002/eji.1830230628 / Eur. J. Immunol / The NH2-terminal domain of rat CD2 binds rat CD48 with a low affinity and binding does not require glycosylation of CD2 by van der Merwe (1993)
10.1002/j.1460-2075.1988.tb03174.x / EMBO J / The MRC OX-45antigen of rat leukocytes and endothelium is in a subset of the immunoglobulin superfamily with CD2, LFA-3 and carcinoembryonic antigens by Killeen (1988)
10.4049/jimmunol.149.5.1636 / J. Immunol / Isolation and characterization of cDNA clones for mouse Ly-9 by Sandrin (1992)
10.4049/jimmunol.151.10.5328 / J. Immunol / Cloning and characterization of the 2B4 gene encoding a molecule associated with non-MHC-restricted killing mediated by activated natural killer cells and T cells by Mathew (1993)
10.1084/jem.171.6.2115 / J. Exp. Med / Structure, expression, and genetic linkage of the mouse BCM1 (OX45 or Blast-1) antigen by Wong (1990)
10.1038/353762a0 / Nature / Sturcture of domain of rat T lymphocyte CD2 antigen by Driscoll (1991)
10.1038/360232a0 / Nature / Crystal structure at 2.8 å resolution of a soluble form of the cell adhesion molecule CD2 by Jones (1992)
10.1038/348411a0 / Nature / Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains by Wang (1990)
10.1038/348419a0 / Nature / Crystal structure of an HIV-binding recombinant fragment of human CD4 by Ryu (1990)
10.1126/science.8493535 / Science / Crystal structure of domains 3 and 4 of rat CD4: relation to the NH2-terminal domains by Brady (1993)
10.1073/pnas.90.24.11613 / Proc. Natl. Acad. Sci / The CD58 (LFA-3) binding site is a localized and highly charged surface area on the AGFCC′C″ face of the human CD2 adhesion domain by Arulanandam (1993)
10.1038/329842a0 / Nature / Monoclonal antibody and ligand binding sites of the T cell erythrocyte receptor (CD2) by Peterson (1987)
10.1084/jem.178.2.549 / J. Exp. Med / Mutational analysis of the CD2/CD58 interaction: the binding site for CD58 lies on one face of the first domain of human CD2 by Somoza (1993)
10.4049/jimmunol.144.4.1215 / J. Immunol / Functional CD2 mutants unable to bind to, or be stimulated by, LFA-3 by Wolff (1990)
10.1073/pnas.85.4.1194 / Proc. Natl. Acad. Sci / Expression of the T-cell surface molecule CD2 and an epitope-loss CD2 mutant to define the role of lymphocyte function-associated antigen 3 (LFA-3) in T-cell activation by Bierer (1988)
10.1002/j.1460-2075.1993.tb06188.x / EMBO J / Affinity and kinetic analysis of the interaction of the cell adhesion molecules rat CD2 and CD48 by van der Merwe (1993)
10.1042/bst021340s / Biochem. Soc. Trans / Measuring very low affinity interactions between immunoglobulin superfamily cell-adhesion molecules by van der Merwe (1993)
10.1042/bst0210952 / Biochem. Soc. Trans / Analysis of the structure and interactions of CD2 by Davis (1993)
10.1111/j.1432-1033.1994.tb18579.x / Eur. J. Biochem / Expression cloning of an equine T-lymphocyte glycoprotein CD2 cDNA: structure-based analysis of conserved sequence elements by Tavernor (1994)
10.1016/S0021-9258(18)54189-2 / J. Biol. Chem / Effects of the imino sugar N-butyldeoxynojirimycin on the N-glycosylation of recombinant gp120 by Karlsson (1993)
10.1093/protein/6.2.229 / Protein Eng / Expression of soluble recombinant glycoproteins with predefined glycosylation: application to the crystallization of the T-cell glycoprotein CD2 by Davis (1993)
10.1006/jmbi.1993.1381 / J. Mol. Biol / Solution structure of a pair of complement modules by nuclear magnetic resonance by Barlow (1993)
10.1016/0969-2126(93)90009-6 / Structure / Structure of the glycosylated adhesion domain of human T lymphocyte glycoprotein CD2 by Withka (1993)
10.1006/jmbi.1994.1312 / J. Mol. Biol / Many of the immunoglobulin superfamily domains in cell adhesion molecules and surface receptors belong to a new structural set which is close to that containing variable domains by Harpaz (1994)
10.1021/bi00092a008 / Biochemistry / 1H resonance assignments and secondary structure of the 13.6 kDa glycosylated adhesion domain of human CD2 by Wyss (1993)
{'key': '10.1016/S0969-2126(94)00076-X_BIB31', 'series-title': 'Sequences of Proteins of Immunological Interest', 'author': 'Kabat', 'year': '1987'} / Sequences of Proteins of Immunological Interest by Kabat (1987)
10.1093/protein/6.8.965 / Protein. Eng / Structural analysis of the CD2 T lymphocyte antigen by site-directed mutgenesis to introduce a disulphide bond into domain 1 by Gray (1993)
10.1016/0167-5699(87)90016-8 / Immunol. Today / A year in the life of the immunoglobulin superfamily by Williams (1987)
10.1016/0022-2836(85)90137-8 / J. Mol. Biol / Domain association in immunoglobulin molecules. The packing of variable domains by Chothia (1985)
10.1016/0092-8674(92)90085-Q / Cell / Crystal structure of a soluble form of the human T cell receptor CD8 at 2.6å resolution by Leahy (1992)
10.1016/S0021-9258(17)46181-3 / J. Biol. Chem / The structure of protein-protein recognition sites by Janin (1990)
10.1016/0092-8674(84)90039-4 / Cell / An alternative pathway of T-cell activation: a functional role for the 50 kd T11 sheep erythrocyte receptor protein by Meuer (1984)
10.1107/S0021889892002656 / J Appl. Crystallogr / Micro-bridges for sitting-drop crystallizations by Harlos (1992)
10.1107/S0021889887009737 / J. Appl. Crystallogr / Automatic indexing of rotation diffraction patterns by Kabsch (1988)
{'key': '10.1016/S0969-2126(94)00076-X_BIB40', 'series-title': 'Data Collection and Processing', 'article-title': 'Oscillation data reduction program', 'author': 'Otwinowski', 'year': '1993'} / Data Collection and Processing / Oscillation data reduction program by Otwinowski (1993)
10.1016/0022-2836(79)90416-9 / J. Mol. Biol / The crystal structure of cat pyruvate kinase at a resolution of 2.6å by Stuart (1979)
10.1016/0076-6879(85)15009-3 / Methods Enzymol / Resolution of phase ambiguity in macromolecular crystallography by Wang (1985)
10.1107/S0108767386099622 / Acta Crystallogr / Improved fourier coefficient for maps using phases from partial structures with errors by Read (1986)
10.1107/S0108767390010224 / Acta Crystallogr / Improved methods for building protein models in electron density maps and the location of errors in these models by Jones (1991)
10.1016/0076-6879(85)15014-7 / Methods Enzymol / Interactive computer graphics: FRODO by Jones (1985)
{'key': '10.1016/S0969-2126(94)00076-X_BIB46', 'series-title': 'X-PLOR. Version 3.1. (A system for X-ray crystallography and NMR)', 'author': 'Brünger', 'year': '1992'} / X-PLOR. Version 3.1. (A system for X-ray crystallography and NMR) by Brünger (1992)
10.1107/S0108767391001071 / Acta Crystallogr / Accurate bond and angle parameters for X-ray protein-structure refinement by Engh (1991)
10.1107/S0108767390002355 / Acta Crystallogr. A / Slow-cooling protocols for crystallographic refinement by simulated annealing by Brünger (1990)
10.1002/jcc.540090407 / J. Comp. Chem / Calculating the electrostatic potential of molecules in solution: method and error assessment by Gilson (1987)
10.1107/S0021889892009944 / J. Appl. Crystallogr / PROCHECK: A program to check stereochemical quality of protein structures by Laskowski (1993)
10.1002/bip.360221211 / Biopolymers / Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features by Kabsch (1983)
10.1107/S0907444993011333 / Acta Crystallogr. D / Detection, delineation, measurement and display of cavities in macromolecular structures by Kleywegt (1994)
10.1107/S0021889891004399 / J. Appl. Crystallogr / MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures by Kraulis (1991)
10.1016/S0021-9258(17)38249-2 / J. Biol. Chem / Preliminary refinement and structural analysis of the Fab fragment from human immunoglobulin New at 2.0 å resolution by Saul (1978)
{'key': '10.1016/S0969-2126(94)00076-X_BIB55', 'first-page': 'in press', 'article-title': 'The human cell-adhesion molecule CD2 binds CD58 (LFA-3) with a very low affinity and an extremely fast disslocation rate but does not bind CD48 or CD59', 'author': 'van der Merwe', 'year': '1994', 'journal-title': 'Biochemistry'} / Biochemistry / The human cell-adhesion molecule CD2 binds CD58 (LFA-3) with a very low affinity and an extremely fast disslocation rate but does not bind CD48 or CD59 by van der Merwe (1994)

Dates

Type	When
Created	21 years ago (Aug. 23, 2004, 2:47 p.m.)
Deposited	2 years, 4 months ago (April 29, 2023, 2:39 a.m.)
Indexed	1 month, 2 weeks ago (July 16, 2025, 9:48 a.m.)
Issued	31 years, 1 month ago (Aug. 1, 1994)
Published	31 years, 1 month ago (Aug. 1, 1994)
Published Print	31 years, 1 month ago (Aug. 1, 1994)

Funders 0

None

BibTeX

@article{Bodian_1994, title={Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5å resolution}, volume={2}, ISSN={0969-2126}, url={http://dx.doi.org/10.1016/s0969-2126(94)00076-x}, DOI={10.1016/s0969-2126(94)00076-x}, number={8}, journal={Structure}, publisher={Elsevier BV}, author={Bodian, Dale L and Jones, E.Yvonne and Harlos, Karl and Stuart, David I and Davis, Simon J}, year={1994}, month=aug, pages={755–766} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        7,
        16
      ]
    ],
    "date-time": "2025-07-16T13:48:42Z",
    "timestamp": 1752673722064
  },
  "reference-count": 55,
  "publisher": "Elsevier BV",
  "issue": "8",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            1994,
            8,
            1
          ]
        ],
        "date-time": "1994-08-01T00:00:00Z",
        "timestamp": 775699200000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1994,
        8
      ]
    ]
  },
  "DOI": "10.1016/s0969-2126(94)00076-x",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2004,
        8,
        23
      ]
    ],
    "date-time": "2004-08-23T18:47:34Z",
    "timestamp": 1093286854000
  },
  "page": "755-766",
  "source": "Crossref",
  "is-referenced-by-count": 125,
  "title": "Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5\u00e5 resolution",
  "prefix": "10.1016",
  "volume": "2",
  "author": [
    {
      "given": "Dale L",
      "family": "Bodian",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "E.Yvonne",
      "family": "Jones",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Karl",
      "family": "Harlos",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "David I",
      "family": "Stuart",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Simon J",
      "family": "Davis",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB1",
      "series-title": "The Leucocyte Antigen Facts Book",
      "author": "Barclay",
      "year": "1993"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB2",
      "doi-asserted-by": "crossref",
      "first-page": "341",
      "DOI": "10.1084/jem.179.1.341",
      "article-title": "Anti-CD2 receptor and anti-CD2 ligand (CD48) antibodies synergize to prolong allograft survival",
      "volume": "79",
      "author": "Qin",
      "year": "1994",
      "journal-title": "J Exp. Med"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB3",
      "doi-asserted-by": "crossref",
      "first-page": "677",
      "DOI": "10.1084/jem.165.3.677",
      "article-title": "Purified lymphocyte function-associated antigen 3 binds to CD2 and mediates T lymphocyte adhesion",
      "volume": "165",
      "author": "Dustin",
      "year": "1987",
      "journal-title": "J. Exp. Med"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB4",
      "doi-asserted-by": "crossref",
      "first-page": "400",
      "DOI": "10.1038/326400a0",
      "article-title": "The T lymphocyte glycoprotein CD2 binds the cell surface ligand LFA-3",
      "volume": "326",
      "author": "Selvaraj",
      "year": "1987",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB5",
      "doi-asserted-by": "crossref",
      "first-page": "1241",
      "DOI": "10.1084/jem.176.5.1241",
      "article-title": "CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation",
      "volume": "176",
      "author": "Kato",
      "year": "1992",
      "journal-title": "J. Exp. Med"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB6",
      "doi-asserted-by": "crossref",
      "first-page": "1373",
      "DOI": "10.1002/eji.1830230628",
      "article-title": "The NH2-terminal domain of rat CD2 binds rat CD48 with a low affinity and binding does not require glycosylation of CD2",
      "volume": "23",
      "author": "van der Merwe",
      "year": "1993",
      "journal-title": "Eur. J. Immunol"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB7",
      "doi-asserted-by": "crossref",
      "first-page": "3087",
      "DOI": "10.1002/j.1460-2075.1988.tb03174.x",
      "article-title": "The MRC OX-45antigen of rat leukocytes and endothelium is in a subset of the immunoglobulin superfamily with CD2, LFA-3 and carcinoembryonic antigens",
      "volume": "7",
      "author": "Killeen",
      "year": "1988",
      "journal-title": "EMBO J"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB8",
      "doi-asserted-by": "crossref",
      "first-page": "1636",
      "DOI": "10.4049/jimmunol.149.5.1636",
      "article-title": "Isolation and characterization of cDNA clones for mouse Ly-9",
      "volume": "149",
      "author": "Sandrin",
      "year": "1992",
      "journal-title": "J. Immunol"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB9",
      "doi-asserted-by": "crossref",
      "first-page": "5328",
      "DOI": "10.4049/jimmunol.151.10.5328",
      "article-title": "Cloning and characterization of the 2B4 gene encoding a molecule associated with non-MHC-restricted killing mediated by activated natural killer cells and T cells",
      "volume": "151",
      "author": "Mathew",
      "year": "1993",
      "journal-title": "J. Immunol"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB10",
      "doi-asserted-by": "crossref",
      "first-page": "2115",
      "DOI": "10.1084/jem.171.6.2115",
      "article-title": "Structure, expression, and genetic linkage of the mouse BCM1 (OX45 or Blast-1) antigen",
      "volume": "171",
      "author": "Wong",
      "year": "1990",
      "journal-title": "J. Exp. Med"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB11",
      "doi-asserted-by": "crossref",
      "first-page": "762",
      "DOI": "10.1038/353762a0",
      "article-title": "Sturcture of domain of rat T lymphocyte CD2 antigen",
      "volume": "353",
      "author": "Driscoll",
      "year": "1991",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB12",
      "doi-asserted-by": "crossref",
      "first-page": "232",
      "DOI": "10.1038/360232a0",
      "article-title": "Crystal structure at 2.8 \u00e5 resolution of a soluble form of the cell adhesion molecule CD2",
      "volume": "360",
      "author": "Jones",
      "year": "1992",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB13",
      "doi-asserted-by": "crossref",
      "first-page": "411",
      "DOI": "10.1038/348411a0",
      "article-title": "Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains",
      "volume": "348",
      "author": "Wang",
      "year": "1990",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB14",
      "doi-asserted-by": "crossref",
      "first-page": "419",
      "DOI": "10.1038/348419a0",
      "article-title": "Crystal structure of an HIV-binding recombinant fragment of human CD4",
      "volume": "348",
      "author": "Ryu",
      "year": "1990",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB15",
      "doi-asserted-by": "crossref",
      "first-page": "979",
      "DOI": "10.1126/science.8493535",
      "article-title": "Crystal structure of domains 3 and 4 of rat CD4: relation to the NH2-terminal domains",
      "volume": "260",
      "author": "Brady",
      "year": "1993",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB16",
      "doi-asserted-by": "crossref",
      "first-page": "11613",
      "DOI": "10.1073/pnas.90.24.11613",
      "article-title": "The CD58 (LFA-3) binding site is a localized and highly charged surface area on the AGFCC\u2032C\u2033 face of the human CD2 adhesion domain",
      "volume": "90",
      "author": "Arulanandam",
      "year": "1993",
      "journal-title": "Proc. Natl. Acad. Sci"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB17",
      "doi-asserted-by": "crossref",
      "first-page": "842",
      "DOI": "10.1038/329842a0",
      "article-title": "Monoclonal antibody and ligand binding sites of the T cell erythrocyte receptor (CD2)",
      "volume": "329",
      "author": "Peterson",
      "year": "1987",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "549",
      "DOI": "10.1084/jem.178.2.549",
      "article-title": "Mutational analysis of the CD2/CD58 interaction: the binding site for CD58 lies on one face of the first domain of human CD2",
      "volume": "178",
      "author": "Somoza",
      "year": "1993",
      "journal-title": "J. Exp. Med"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "1215",
      "DOI": "10.4049/jimmunol.144.4.1215",
      "article-title": "Functional CD2 mutants unable to bind to, or be stimulated by, LFA-3",
      "volume": "144",
      "author": "Wolff",
      "year": "1990",
      "journal-title": "J. Immunol"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB20",
      "doi-asserted-by": "crossref",
      "first-page": "1194",
      "DOI": "10.1073/pnas.85.4.1194",
      "article-title": "Expression of the T-cell surface molecule CD2 and an epitope-loss CD2 mutant to define the role of lymphocyte function-associated antigen 3 (LFA-3) in T-cell activation",
      "volume": "85",
      "author": "Bierer",
      "year": "1988",
      "journal-title": "Proc. Natl. Acad. Sci"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "4945",
      "DOI": "10.1002/j.1460-2075.1993.tb06188.x",
      "article-title": "Affinity and kinetic analysis of the interaction of the cell adhesion molecules rat CD2 and CD48",
      "volume": "12",
      "author": "van der Merwe",
      "year": "1993",
      "journal-title": "EMBO J"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "340s",
      "DOI": "10.1042/bst021340s",
      "article-title": "Measuring very low affinity interactions between immunoglobulin superfamily cell-adhesion molecules",
      "volume": "21",
      "author": "van der Merwe",
      "year": "1993",
      "journal-title": "Biochem. Soc. Trans"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "952",
      "DOI": "10.1042/bst0210952",
      "article-title": "Analysis of the structure and interactions of CD2",
      "volume": "21",
      "author": "Davis",
      "year": "1993",
      "journal-title": "Biochem. Soc. Trans"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "969",
      "DOI": "10.1111/j.1432-1033.1994.tb18579.x",
      "article-title": "Expression cloning of an equine T-lymphocyte glycoprotein CD2 cDNA: structure-based analysis of conserved sequence elements",
      "volume": "219",
      "author": "Tavernor",
      "year": "1994",
      "journal-title": "Eur. J. Biochem"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "570",
      "DOI": "10.1016/S0021-9258(18)54189-2",
      "article-title": "Effects of the imino sugar N-butyldeoxynojirimycin on the N-glycosylation of recombinant gp120",
      "volume": "268",
      "author": "Karlsson",
      "year": "1993",
      "journal-title": "J. Biol. Chem"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "229",
      "DOI": "10.1093/protein/6.2.229",
      "article-title": "Expression of soluble recombinant glycoproteins with predefined glycosylation: application to the crystallization of the T-cell glycoprotein CD2",
      "volume": "6",
      "author": "Davis",
      "year": "1993",
      "journal-title": "Protein Eng"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "268",
      "DOI": "10.1006/jmbi.1993.1381",
      "article-title": "Solution structure of a pair of complement modules by nuclear magnetic resonance",
      "volume": "232",
      "author": "Barlow",
      "year": "1993",
      "journal-title": "J. Mol. Biol"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "69",
      "DOI": "10.1016/0969-2126(93)90009-6",
      "article-title": "Structure of the glycosylated adhesion domain of human T lymphocyte glycoprotein CD2",
      "volume": "1",
      "author": "Withka",
      "year": "1993",
      "journal-title": "Structure"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "528",
      "DOI": "10.1006/jmbi.1994.1312",
      "article-title": "Many of the immunoglobulin superfamily domains in cell adhesion molecules and surface receptors belong to a new structural set which is close to that containing variable domains",
      "volume": "238",
      "author": "Harpaz",
      "year": "1994",
      "journal-title": "J. Mol. Biol"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "10995",
      "DOI": "10.1021/bi00092a008",
      "article-title": "1H resonance assignments and secondary structure of the 13.6 kDa glycosylated adhesion domain of human CD2",
      "volume": "32",
      "author": "Wyss",
      "year": "1993",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB31",
      "series-title": "Sequences of Proteins of Immunological Interest",
      "author": "Kabat",
      "year": "1987"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "965",
      "DOI": "10.1093/protein/6.8.965",
      "article-title": "Structural analysis of the CD2 T lymphocyte antigen by site-directed mutgenesis to introduce a disulphide bond into domain 1",
      "volume": "6",
      "author": "Gray",
      "year": "1993",
      "journal-title": "Protein. Eng"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "298",
      "DOI": "10.1016/0167-5699(87)90016-8",
      "article-title": "A year in the life of the immunoglobulin superfamily",
      "volume": "8",
      "author": "Williams",
      "year": "1987",
      "journal-title": "Immunol. Today"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "651",
      "DOI": "10.1016/0022-2836(85)90137-8",
      "article-title": "Domain association in immunoglobulin molecules. The packing of variable domains",
      "volume": "186",
      "author": "Chothia",
      "year": "1985",
      "journal-title": "J. Mol. Biol"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "1145",
      "DOI": "10.1016/0092-8674(92)90085-Q",
      "article-title": "Crystal structure of a soluble form of the human T cell receptor CD8 at 2.6\u00e5 resolution",
      "volume": "68",
      "author": "Leahy",
      "year": "1992",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "16027",
      "DOI": "10.1016/S0021-9258(17)46181-3",
      "article-title": "The structure of protein-protein recognition sites",
      "volume": "265",
      "author": "Janin",
      "year": "1990",
      "journal-title": "J. Biol. Chem"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "897",
      "DOI": "10.1016/0092-8674(84)90039-4",
      "article-title": "An alternative pathway of T-cell activation: a functional role for the 50 kd T11 sheep erythrocyte receptor protein",
      "volume": "36",
      "author": "Meuer",
      "year": "1984",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "536",
      "DOI": "10.1107/S0021889892002656",
      "article-title": "Micro-bridges for sitting-drop crystallizations",
      "volume": "25",
      "author": "Harlos",
      "year": "1992",
      "journal-title": "J Appl. Crystallogr"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "67",
      "DOI": "10.1107/S0021889887009737",
      "article-title": "Automatic indexing of rotation diffraction patterns",
      "volume": "21",
      "author": "Kabsch",
      "year": "1988",
      "journal-title": "J. Appl. Crystallogr"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB40",
      "series-title": "Data Collection and Processing",
      "article-title": "Oscillation data reduction program",
      "author": "Otwinowski",
      "year": "1993"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "109",
      "DOI": "10.1016/0022-2836(79)90416-9",
      "article-title": "The crystal structure of cat pyruvate kinase at a resolution of 2.6\u00e5",
      "volume": "134",
      "author": "Stuart",
      "year": "1979",
      "journal-title": "J. Mol. Biol"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "90",
      "DOI": "10.1016/0076-6879(85)15009-3",
      "article-title": "Resolution of phase ambiguity in macromolecular crystallography",
      "volume": "115",
      "author": "Wang",
      "year": "1985",
      "journal-title": "Methods Enzymol"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "140",
      "DOI": "10.1107/S0108767386099622",
      "article-title": "Improved fourier coefficient for maps using phases from partial structures with errors",
      "volume": "42",
      "author": "Read",
      "year": "1986",
      "journal-title": "Acta Crystallogr"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "110",
      "DOI": "10.1107/S0108767390010224",
      "article-title": "Improved methods for building protein models in electron density maps and the location of errors in these models",
      "volume": "47",
      "author": "Jones",
      "year": "1991",
      "journal-title": "Acta Crystallogr"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "157",
      "DOI": "10.1016/0076-6879(85)15014-7",
      "article-title": "Interactive computer graphics: FRODO",
      "volume": "115",
      "author": "Jones",
      "year": "1985",
      "journal-title": "Methods Enzymol"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB46",
      "series-title": "X-PLOR. Version 3.1. (A system for X-ray crystallography and NMR)",
      "author": "Br\u00fcnger",
      "year": "1992"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "392",
      "DOI": "10.1107/S0108767391001071",
      "article-title": "Accurate bond and angle parameters for X-ray protein-structure refinement",
      "volume": "47",
      "author": "Engh",
      "year": "1991",
      "journal-title": "Acta Crystallogr"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "585",
      "DOI": "10.1107/S0108767390002355",
      "article-title": "Slow-cooling protocols for crystallographic refinement by simulated annealing",
      "volume": "46",
      "author": "Br\u00fcnger",
      "year": "1990",
      "journal-title": "Acta Crystallogr. A"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "327",
      "DOI": "10.1002/jcc.540090407",
      "article-title": "Calculating the electrostatic potential of molecules in solution: method and error assessment",
      "volume": "9",
      "author": "Gilson",
      "year": "1987",
      "journal-title": "J. Comp. Chem"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB50",
      "doi-asserted-by": "crossref",
      "first-page": "283",
      "DOI": "10.1107/S0021889892009944",
      "article-title": "PROCHECK: A program to check stereochemical quality of protein structures",
      "volume": "26",
      "author": "Laskowski",
      "year": "1993",
      "journal-title": "J. Appl. Crystallogr"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB51",
      "doi-asserted-by": "crossref",
      "first-page": "2577",
      "DOI": "10.1002/bip.360221211",
      "article-title": "Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features",
      "volume": "22",
      "author": "Kabsch",
      "year": "1983",
      "journal-title": "Biopolymers"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB52",
      "doi-asserted-by": "crossref",
      "first-page": "178",
      "DOI": "10.1107/S0907444993011333",
      "article-title": "Detection, delineation, measurement and display of cavities in macromolecular structures",
      "volume": "50",
      "author": "Kleywegt",
      "year": "1994",
      "journal-title": "Acta Crystallogr. D"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB53",
      "doi-asserted-by": "crossref",
      "first-page": "946",
      "DOI": "10.1107/S0021889891004399",
      "article-title": "MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures",
      "volume": "24",
      "author": "Kraulis",
      "year": "1991",
      "journal-title": "J. Appl. Crystallogr"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB54",
      "doi-asserted-by": "crossref",
      "first-page": "585",
      "DOI": "10.1016/S0021-9258(17)38249-2",
      "article-title": "Preliminary refinement and structural analysis of the Fab fragment from human immunoglobulin New at 2.0 \u00e5 resolution",
      "volume": "253",
      "author": "Saul",
      "year": "1978",
      "journal-title": "J. Biol. Chem"
    },
    {
      "key": "10.1016/S0969-2126(94)00076-X_BIB55",
      "first-page": "in press",
      "article-title": "The human cell-adhesion molecule CD2 binds CD58 (LFA-3) with a very low affinity and an extremely fast disslocation rate but does not bind CD48 or CD59",
      "author": "van der Merwe",
      "year": "1994",
      "journal-title": "Biochemistry"
    }
  ],
  "container-title": "Structure",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S096921269400076X?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S096921269400076X?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        4,
        29
      ]
    ],
    "date-time": "2023-04-29T06:39:10Z",
    "timestamp": 1682750350000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S096921269400076X"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1994,
        8
      ]
    ]
  },
  "references-count": 55,
  "journal-issue": {
    "issue": "8",
    "published-print": {
      "date-parts": [
        [
          1994,
          8
        ]
      ]
    }
  },
  "alternative-id": [
    "S096921269400076X"
  ],
  "URL": "http://dx.doi.org/10.1016/S0969-2126(94)00076-X",
  "relation": {},
  "ISSN": [
    "0969-2126"
  ],
  "subject": [],
  "container-title-short": "Structure",
  "published": {
    "date-parts": [
      [
        1994,
        8
      ]
    ]
  }
}