DOI: 10.1016/s0969-2126(00)00533-5. Structure and Mechanism of Homoserine Kinase

Structure and Mechanism of Homoserine Kinase

10.1016/s0969-2126(00)00533-5

Crossref journal-article

Elsevier BV

Structure (78)

Bibliography

Zhou, T., Daugherty, M., Grishin, N. V., Osterman, A. L., & Zhang, H. (2000). Structure and Mechanism of Homoserine Kinase. Structure, 8(12), 1247â1257.

Authors 5

Tianjun Zhou (first)
Matthew Daugherty (additional)
Nick V. Grishin (additional)
Andrei L. Osterman (additional)
Hong Zhang (additional)

References 60 Referenced 113

10.1096/fasebj.9.15.8529838 / FASEB J. / Mechanisms of phosphoryl and acyl transfer. by Cleland (1995)
10.1016/S0969-2126(98)00043-4 / Structure / How do kinases transfer phosphoryl groups? by Matte (1998)
10.1016/0968-0004(90)90281-F / Trends Biochem. Sci. / The P-loop — a common motif in ATP- and GTP-binding proteins by Saraste (1990)
10.1073/pnas.89.16.7290 / Proc. Natl. Acad. Sci. USA. / An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins. by Bork (1992)
10.1016/0968-0004(94)90022-1 / Trends Biochem. Sci. / The glycine-rich sequence of protein kinases by Bossemeyer (1994)
10.1128/MCB.11.2.620 / Mol. Cell. Biol. / Cloning and characterization of ERG8, an essential gene of Saccharomyces cerevisiae that encodes phosphomevalonate kinase by Tsay (1991)
10.1002/pro.5560020104 / Protein Sci. / Convergent evolution of similar enzymatic function on different protein folds by Bork (1993)
10.1073/pnas.96.24.13714 / Proc. Natl. Acad. Sci. USA. / Isopentenyl diphosphate biosynthesis via a mevalonate-independent pathway by Lange (1999)
10.1007/PL00006804 / Curr. Microbiol. / The Saccharomyces cerevisiae mevalonate diphosphate decarboxylase (erg19p) forms homodimers in vivo, and a single substitution in a structurally conserved region impairs dimerization by Cordier (1999)
{'key': '10.1016/S0969-2126(00)00533-5_BIB10', 'series-title': 'The Metabolic and Molecular Bases of Inherited Disease', 'article-title': 'Disorders of galactose metabolism', 'author': 'Segal', 'year': '1995'} / The Metabolic and Molecular Bases of Inherited Disease / Disorders of galactose metabolism by Segal (1995)
10.1093/genetics/53.3.609 / Saccharomyces Genetics / Genetic and biochemical studies of genes controlling the synthesis of threonine and methionine in by Robichon-Szulmajster (1966)
10.1016/0003-9861(58)90367-9 / Arch. Biochem. Biophys. / Regulation of Threonine Biosynthesis in Escherichia coli by Wormser (1958)
10.1128/JB.118.2.577-581.1974 / J. Bacteriol. / Homoserine kinase from Escherichia coli K-12 by Theze (1974)
10.1111/j.1432-1033.1976.tb10186.x / Eur. J. Biochem. / Homoserine kinase from Escherichia coli K12 by Burr (1976)
10.1016/0003-9861(84)90209-1 / Arch. Biochem. Biophys. / Homoserine kinase of Escherichia coli: kinetic mechanism and inhibition by L-aspartate semialdehyde by Shames (1984)
10.1021/bi962203z / Biochemistry / Substrate specificity and identification of functional groups of homoserine kinase from Escherichia coli by Huo (1996)
10.1111/j.1365-2958.1992.tb01768.x / Mol. Microbiol. / Isolation, organization and expression of the Pseudomonas aeruginosa threonine genes by Clepet (1992)
10.1099/00221287-145-11-3273 / Microbiology / Organization of threonine biosynthesis genes from the obligate methylotroph Methylobacillus flagellatus by Marchenko (1999)
10.1016/S0092-8674(00)80274-3 / Cell / Structure of an enzyme required for aminoglycoside antibiotic resistance reveals homology to eukaryotic protein kinases by Hon (1997)
10.1099/13500872-145-4-845 / Microbiology / ThrH, a homoserine kinase isozyme with in vivo phosphoserine phosphatase activity in Pseudomonas aeruginosa by Patte (1999)
10.1006/jmbi.1994.1711 / J. Mol. Biol. / Computer analysis of bacterial haloacid dehalogenases defines a large superfamily of hydrolases with diverse specificity by Koonin (1994)
10.1074/jbc.273.23.14107 / J. Biol. Chem. / A new class of phosphotransferases phosphorylated on an aspartate residue in an amino-terminal DXDX(T/V) motif by Collet (1998)
10.1038/nsb0195-25 / Nat. Struct. Biol. / A ribosomal protein module in EF-G and DNA gyrase by Murzin (1995)
10.1016/S0092-8674(00)80717-5 / Cell / Transformation of MutL by ATP binding and hydrolysis by Ban (1999)
10.1016/S0968-0004(00)89105-7 / Trends Biochem. Sci. / Dali by Holm (1995)
10.1016/S0969-2126(96)00061-5 / Structure / The structure of elongation factor G in complex with GDP by al-Karadaghi (1996)
10.1038/358768a0 / Nature / The structure of ribosomal protein S5 reveals sites of interaction with 16S rRNA by Ramakrishnan (1992)
10.1126/science.280.5364.752 / Science / Ribonuclease P protein structure by Stams (1998)
10.1016/S0092-8674(00)81621-9 / Cell / Crystal structure and ATPase activity of MutL by Ban (1998)
10.1038/351624a0 / Nature / Crystal structure of an N-terminal fragment of the DNA gyrase B protein by Wigley (1991)
10.1016/S0022-2836(05)80134-2 / J. Mol. Biol. / Scop by Murzin (1995)
10.1016/S0969-2126(97)00260-8 / Structure / Cath by Orengo (1997)
10.1038/35030006 / Nature / Structure of the 30S ribosomal subunit by Wimberly (2000)
10.1126/science.1948029 / Science / X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil by O'Shea (1991)
10.1006/prep.1999.1106 / Protein Expr. Purif. / Overexpression, purification, and characterization of the thermostable mevalonate kinase from Methanococcus jannaschii by Huang (1999)
10.1515/znc-1979-5-608 / Z. Naturforsch C / A 1H NMR study of the syn-anti dynamic equilibrium in adenine nucleosides and nucleotides with the aid of some synthetic model analogues with fixed conformations by Dudycz (1979)
10.1073/pnas.76.2.553 / Proc. Natl. Acad. Sci. USA / Conformation of nucleosides by Miles (1979)
10.1007/BF00527633 / Theor. Chim. Acta / Molecular orbital calculations on the conformation of nucleic acids and their constituents, paper VII. Conformation of the sugar ring in β-nucleosides by Saran (1973)
10.1038/nsb0496-355 / Nat. Struct. Biol. / Snapshot of an enzyme reaction intermediate in the structure of the ATP- Mg2+-oxalate ternary complex of Escherichia coli PEP carboxykinase by Tari (1996)
10.1038/1843 / Nat. Struct. Biol. / Structure of the ATP-dependent oligomerization domain of N-ethylmaleimide sensitive factor complexed with ATP by Yu (1998)
10.1016/0959-440X(92)90178-A / Curr. Opin. Struct. Biol. / Binding of nucleotides to proteins by Schultz (1992)
10.1016/S0969-2126(98)00038-0 / Structure / The structure of SAICAR synthase by Levdikov (1998)
10.1093/nar/27.1.254 / Nucleic Acids Res. / Scop by Hubbard (1999)
10.1073/pnas.97.7.3154 / Proc. Natl. Acad. Sci. USA / The insertion of two amino acids into a transcriptional inducer converts it into a galactokinase by Platt (2000)
10.1016/0959-440X(94)90272-0 / Curr. Opin. Struct. Biol. / Domain movements in protein kinases by Cox (1994)
10.1021/bi00188a001 / Biochemistry / Structural mechanisms for domain movements in proteins by Gerstein (1994)
10.1093/nar/25.17.3389 / Nucleic Acids Res. / Gapped BLAST and PSI-BLAST by Altschul (1997)
10.1107/S0021889898010504 / J. Appl. Cryst. / The design and implementation of Snb VERSION 2.0 by Weeks (1999)
Otwinowski, Z. (1991). Maximum likelihood refinement of heavy atom parameters, in Isomorphous Replacement and Anomalous Scattering, W. Wolf, P.R. Evans, and A.G.W. Leslie, eds. (Warrington, UK: Daresbury Laboratory), pp. 80–86.
CCP4 (Collaborative Computational Project 4) (1994). The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D 50, 760–763. (10.1107/S0907444994003112)
{'key': '10.1016/S0969-2126(00)00533-5_BIB51', 'first-page': '34', 'article-title': "Dm'", 'volume': '31', 'author': 'Cowtan', 'year': '1994', 'journal-title': 'Joint CCP4 and ESF-EACBM Newsletter on Protein Crystallography'} / Joint CCP4 and ESF-EACBM Newsletter on Protein Crystallography / Dm' by Cowtan (1994)
10.1107/S0108767390010224 / Acta Crystallogr. A / Improved methods for building protein models in electron density maps and the location of errors in these models by Jones (1991)
10.1107/S0907444996012255 / Acta Cryst. D / Refinement of macromolecular structures by the maximum-likelihood method by Murshudov (1997)
10.1107/S0907444998003254 / Acta Crystallogr. D Biol. Crystallogr / Crystallography & NMR system by Brünger (1998)
10.1107/S0907444998007100 / Acta Crystallogr. D / Databases in protein crystallography by Kleywegt (1998)
10.1093/nar/22.22.4673 / Nucleic Acids Res. / Clustal w by Thompson (1994)
10.1098/rspa.1961.0220 / Proc. Roy. Soc. London Ser. A / The structure of haemoglobin. VIII. A three-dimetional Fourier synthesis at 5.5 Å resolution by Cullis (1961)
10.1107/S0021889891004399 / J. Appl. Crystallogr. / Molscript by Kraulis (1991)
10.1016/S1093-3263(97)00021-1 / J. Mol. Graph. Model. / An extensively modified version of Molscript that includes greatly enhanced coloring capabilities by Esnouf (1997)
{'key': '10.1016/S0969-2126(00)00533-5_BIB61', 'series-title': 'GRASP', 'author': 'Nicholls', 'year': '1992'} / GRASP by Nicholls (1992)

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 3:48 p.m.)
Deposited	4 years, 3 months ago (May 10, 2021, 5:56 p.m.)
Indexed	2 weeks, 6 days ago (Aug. 12, 2025, 6:07 p.m.)
Issued	24 years, 9 months ago (Dec. 1, 2000)
Published	24 years, 9 months ago (Dec. 1, 2000)
Published Print	24 years, 9 months ago (Dec. 1, 2000)

Funders 0

None

BibTeX

@article{Zhou_2000, title={Structure and Mechanism of Homoserine Kinase}, volume={8}, ISSN={0969-2126}, url={http://dx.doi.org/10.1016/s0969-2126(00)00533-5}, DOI={10.1016/s0969-2126(00)00533-5}, number={12}, journal={Structure}, publisher={Elsevier BV}, author={Zhou, Tianjun and Daugherty, Matthew and Grishin, Nick V. and Osterman, Andrei L. and Zhang, Hong}, year={2000}, month=dec, pages={1247–1257} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        12
      ]
    ],
    "date-time": "2025-08-12T22:07:42Z",
    "timestamp": 1755036462821
  },
  "reference-count": 60,
  "publisher": "Elsevier BV",
  "issue": "12",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2000,
            12,
            1
          ]
        ],
        "date-time": "2000-12-01T00:00:00Z",
        "timestamp": 975628800000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    },
    {
      "start": {
        "date-parts": [
          [
            2013,
            7,
            17
          ]
        ],
        "date-time": "2013-07-17T00:00:00Z",
        "timestamp": 1374019200000
      },
      "content-version": "vor",
      "delay-in-days": 4611,
      "URL": "https://www.elsevier.com/open-access/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2000,
        12
      ]
    ]
  },
  "DOI": "10.1016/s0969-2126(00)00533-5",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        25
      ]
    ],
    "date-time": "2002-07-25T19:48:17Z",
    "timestamp": 1027626497000
  },
  "page": "1247-1257",
  "source": "Crossref",
  "is-referenced-by-count": 113,
  "title": "Structure and Mechanism of Homoserine Kinase",
  "prefix": "10.1016",
  "volume": "8",
  "author": [
    {
      "given": "Tianjun",
      "family": "Zhou",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Matthew",
      "family": "Daugherty",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Nick V.",
      "family": "Grishin",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Andrei L.",
      "family": "Osterman",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Hong",
      "family": "Zhang",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB1",
      "doi-asserted-by": "crossref",
      "first-page": "1585",
      "DOI": "10.1096/fasebj.9.15.8529838",
      "article-title": "Mechanisms of phosphoryl and acyl transfer.",
      "volume": "9",
      "author": "Cleland",
      "year": "1995",
      "journal-title": "FASEB J."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB2",
      "doi-asserted-by": "crossref",
      "first-page": "413",
      "DOI": "10.1016/S0969-2126(98)00043-4",
      "article-title": "How do kinases transfer phosphoryl groups?",
      "volume": "6",
      "author": "Matte",
      "year": "1998",
      "journal-title": "Structure"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB3",
      "doi-asserted-by": "crossref",
      "first-page": "430",
      "DOI": "10.1016/0968-0004(90)90281-F",
      "article-title": "The P-loop \u2014 a common motif in ATP- and GTP-binding proteins",
      "volume": "15",
      "author": "Saraste",
      "year": "1990",
      "journal-title": "Trends Biochem. Sci."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB4",
      "doi-asserted-by": "crossref",
      "first-page": "7290",
      "DOI": "10.1073/pnas.89.16.7290",
      "article-title": "An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins.",
      "volume": "89",
      "author": "Bork",
      "year": "1992",
      "journal-title": "Proc. Natl. Acad. Sci. USA."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB5",
      "doi-asserted-by": "crossref",
      "first-page": "201",
      "DOI": "10.1016/0968-0004(94)90022-1",
      "article-title": "The glycine-rich sequence of protein kinases",
      "volume": "19",
      "author": "Bossemeyer",
      "year": "1994",
      "journal-title": "Trends Biochem. Sci."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB6",
      "doi-asserted-by": "crossref",
      "first-page": "620",
      "DOI": "10.1128/MCB.11.2.620",
      "article-title": "Cloning and characterization of ERG8, an essential gene of Saccharomyces cerevisiae that encodes phosphomevalonate kinase",
      "volume": "11",
      "author": "Tsay",
      "year": "1991",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB7",
      "doi-asserted-by": "crossref",
      "first-page": "31",
      "DOI": "10.1002/pro.5560020104",
      "article-title": "Convergent evolution of similar enzymatic function on different protein folds",
      "volume": "2",
      "author": "Bork",
      "year": "1993",
      "journal-title": "Protein Sci."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB8",
      "doi-asserted-by": "crossref",
      "first-page": "13714",
      "DOI": "10.1073/pnas.96.24.13714",
      "article-title": "Isopentenyl diphosphate biosynthesis via a mevalonate-independent pathway",
      "volume": "96",
      "author": "Lange",
      "year": "1999",
      "journal-title": "Proc. Natl. Acad. Sci. USA."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB9",
      "doi-asserted-by": "crossref",
      "first-page": "290",
      "DOI": "10.1007/PL00006804",
      "article-title": "The Saccharomyces cerevisiae mevalonate diphosphate decarboxylase (erg19p) forms homodimers in vivo, and a single substitution in a structurally conserved region impairs dimerization",
      "volume": "38",
      "author": "Cordier",
      "year": "1999",
      "journal-title": "Curr. Microbiol."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB10",
      "series-title": "The Metabolic and Molecular Bases of Inherited Disease",
      "article-title": "Disorders of galactose metabolism",
      "author": "Segal",
      "year": "1995"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB11",
      "doi-asserted-by": "crossref",
      "first-page": "609",
      "DOI": "10.1093/genetics/53.3.609",
      "article-title": "Genetic and biochemical studies of genes controlling the synthesis of threonine and methionine in",
      "volume": "53",
      "author": "Robichon-Szulmajster",
      "year": "1966",
      "journal-title": "Saccharomyces Genetics"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB12",
      "doi-asserted-by": "crossref",
      "first-page": "416",
      "DOI": "10.1016/0003-9861(58)90367-9",
      "article-title": "Regulation of Threonine Biosynthesis in Escherichia coli",
      "volume": "78",
      "author": "Wormser",
      "year": "1958",
      "journal-title": "Arch. Biochem. Biophys."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB13",
      "doi-asserted-by": "crossref",
      "first-page": "577",
      "DOI": "10.1128/JB.118.2.577-581.1974",
      "article-title": "Homoserine kinase from Escherichia coli K-12",
      "volume": "118",
      "author": "Theze",
      "year": "1974",
      "journal-title": "J. Bacteriol."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB14",
      "doi-asserted-by": "crossref",
      "first-page": "519",
      "DOI": "10.1111/j.1432-1033.1976.tb10186.x",
      "article-title": "Homoserine kinase from Escherichia coli K12",
      "volume": "62",
      "author": "Burr",
      "year": "1976",
      "journal-title": "Eur. J. Biochem."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB15",
      "doi-asserted-by": "crossref",
      "first-page": "359",
      "DOI": "10.1016/0003-9861(84)90209-1",
      "article-title": "Homoserine kinase of Escherichia coli: kinetic mechanism and inhibition by L-aspartate semialdehyde",
      "volume": "235",
      "author": "Shames",
      "year": "1984",
      "journal-title": "Arch. Biochem. Biophys."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB16",
      "doi-asserted-by": "crossref",
      "first-page": "16180",
      "DOI": "10.1021/bi962203z",
      "article-title": "Substrate specificity and identification of functional groups of homoserine kinase from Escherichia coli",
      "volume": "35",
      "author": "Huo",
      "year": "1996",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB17",
      "doi-asserted-by": "crossref",
      "first-page": "3109",
      "DOI": "10.1111/j.1365-2958.1992.tb01768.x",
      "article-title": "Isolation, organization and expression of the Pseudomonas aeruginosa threonine genes",
      "volume": "6",
      "author": "Clepet",
      "year": "1992",
      "journal-title": "Mol. Microbiol."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "3273",
      "DOI": "10.1099/00221287-145-11-3273",
      "article-title": "Organization of threonine biosynthesis genes from the obligate methylotroph Methylobacillus flagellatus",
      "volume": "145",
      "author": "Marchenko",
      "year": "1999",
      "journal-title": "Microbiology"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "887",
      "DOI": "10.1016/S0092-8674(00)80274-3",
      "article-title": "Structure of an enzyme required for aminoglycoside antibiotic resistance reveals homology to eukaryotic protein kinases",
      "volume": "89",
      "author": "Hon",
      "year": "1997",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB20",
      "doi-asserted-by": "crossref",
      "first-page": "845",
      "DOI": "10.1099/13500872-145-4-845",
      "article-title": "ThrH, a homoserine kinase isozyme with in vivo phosphoserine phosphatase activity in Pseudomonas aeruginosa",
      "volume": "145",
      "author": "Patte",
      "year": "1999",
      "journal-title": "Microbiology"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "125",
      "DOI": "10.1006/jmbi.1994.1711",
      "article-title": "Computer analysis of bacterial haloacid dehalogenases defines a large superfamily of hydrolases with diverse specificity",
      "volume": "244",
      "author": "Koonin",
      "year": "1994",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "14107",
      "DOI": "10.1074/jbc.273.23.14107",
      "article-title": "A new class of phosphotransferases phosphorylated on an aspartate residue in an amino-terminal DXDX(T/V) motif",
      "volume": "273",
      "author": "Collet",
      "year": "1998",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "25",
      "DOI": "10.1038/nsb0195-25",
      "article-title": "A ribosomal protein module in EF-G and DNA gyrase",
      "volume": "2",
      "author": "Murzin",
      "year": "1995",
      "journal-title": "Nat. Struct. Biol."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "85",
      "DOI": "10.1016/S0092-8674(00)80717-5",
      "article-title": "Transformation of MutL by ATP binding and hydrolysis",
      "volume": "97",
      "author": "Ban",
      "year": "1999",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "478",
      "DOI": "10.1016/S0968-0004(00)89105-7",
      "article-title": "Dali",
      "volume": "20",
      "author": "Holm",
      "year": "1995",
      "journal-title": "Trends Biochem. Sci."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "555",
      "DOI": "10.1016/S0969-2126(96)00061-5",
      "article-title": "The structure of elongation factor G in complex with GDP",
      "volume": "4",
      "author": "al-Karadaghi",
      "year": "1996",
      "journal-title": "Structure"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "768",
      "DOI": "10.1038/358768a0",
      "article-title": "The structure of ribosomal protein S5 reveals sites of interaction with 16S rRNA",
      "volume": "358",
      "author": "Ramakrishnan",
      "year": "1992",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "752",
      "DOI": "10.1126/science.280.5364.752",
      "article-title": "Ribonuclease P protein structure",
      "volume": "280",
      "author": "Stams",
      "year": "1998",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "541",
      "DOI": "10.1016/S0092-8674(00)81621-9",
      "article-title": "Crystal structure and ATPase activity of MutL",
      "volume": "95",
      "author": "Ban",
      "year": "1998",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "624",
      "DOI": "10.1038/351624a0",
      "article-title": "Crystal structure of an N-terminal fragment of the DNA gyrase B protein",
      "volume": "351",
      "author": "Wigley",
      "year": "1991",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "536",
      "DOI": "10.1016/S0022-2836(05)80134-2",
      "article-title": "Scop",
      "volume": "247",
      "author": "Murzin",
      "year": "1995",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "1093",
      "DOI": "10.1016/S0969-2126(97)00260-8",
      "article-title": "Cath",
      "volume": "5",
      "author": "Orengo",
      "year": "1997",
      "journal-title": "Structure"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "327",
      "DOI": "10.1038/35030006",
      "article-title": "Structure of the 30S ribosomal subunit",
      "volume": "407",
      "author": "Wimberly",
      "year": "2000",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "539",
      "DOI": "10.1126/science.1948029",
      "article-title": "X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil",
      "volume": "254",
      "author": "O'Shea",
      "year": "1991",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "33",
      "DOI": "10.1006/prep.1999.1106",
      "article-title": "Overexpression, purification, and characterization of the thermostable mevalonate kinase from Methanococcus jannaschii",
      "volume": "17",
      "author": "Huang",
      "year": "1999",
      "journal-title": "Protein Expr. Purif."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "359",
      "DOI": "10.1515/znc-1979-5-608",
      "article-title": "A 1H NMR study of the syn-anti dynamic equilibrium in adenine nucleosides and nucleotides with the aid of some synthetic model analogues with fixed conformations",
      "volume": "34",
      "author": "Dudycz",
      "year": "1979",
      "journal-title": "Z. Naturforsch C"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "553",
      "DOI": "10.1073/pnas.76.2.553",
      "article-title": "Conformation of nucleosides",
      "volume": "76",
      "author": "Miles",
      "year": "1979",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "31",
      "DOI": "10.1007/BF00527633",
      "article-title": "Molecular orbital calculations on the conformation of nucleic acids and their constituents, paper VII. Conformation of the sugar ring in \u03b2-nucleosides",
      "volume": "30",
      "author": "Saran",
      "year": "1973",
      "journal-title": "Theor. Chim. Acta"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "355",
      "DOI": "10.1038/nsb0496-355",
      "article-title": "Snapshot of an enzyme reaction intermediate in the structure of the ATP- Mg2+-oxalate ternary complex of Escherichia coli PEP carboxykinase",
      "volume": "3",
      "author": "Tari",
      "year": "1996",
      "journal-title": "Nat. Struct. Biol."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "803",
      "DOI": "10.1038/1843",
      "article-title": "Structure of the ATP-dependent oligomerization domain of N-ethylmaleimide sensitive factor complexed with ATP",
      "volume": "5",
      "author": "Yu",
      "year": "1998",
      "journal-title": "Nat. Struct. Biol."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "61",
      "DOI": "10.1016/0959-440X(92)90178-A",
      "article-title": "Binding of nucleotides to proteins",
      "volume": "2",
      "author": "Schultz",
      "year": "1992",
      "journal-title": "Curr. Opin. Struct. Biol."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "363",
      "DOI": "10.1016/S0969-2126(98)00038-0",
      "article-title": "The structure of SAICAR synthase",
      "volume": "6",
      "author": "Levdikov",
      "year": "1998",
      "journal-title": "Structure"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "254",
      "DOI": "10.1093/nar/27.1.254",
      "article-title": "Scop",
      "volume": "27",
      "author": "Hubbard",
      "year": "1999",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "3154",
      "DOI": "10.1073/pnas.97.7.3154",
      "article-title": "The insertion of two amino acids into a transcriptional inducer converts it into a galactokinase",
      "volume": "97",
      "author": "Platt",
      "year": "2000",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "893",
      "DOI": "10.1016/0959-440X(94)90272-0",
      "article-title": "Domain movements in protein kinases",
      "volume": "4",
      "author": "Cox",
      "year": "1994",
      "journal-title": "Curr. Opin. Struct. Biol."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "6739",
      "DOI": "10.1021/bi00188a001",
      "article-title": "Structural mechanisms for domain movements in proteins",
      "volume": "33",
      "author": "Gerstein",
      "year": "1994",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "3389",
      "DOI": "10.1093/nar/25.17.3389",
      "article-title": "Gapped BLAST and PSI-BLAST",
      "volume": "25",
      "author": "Altschul",
      "year": "1997",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "120",
      "DOI": "10.1107/S0021889898010504",
      "article-title": "The design and implementation of Snb VERSION 2.0",
      "volume": "32",
      "author": "Weeks",
      "year": "1999",
      "journal-title": "J. Appl. Cryst."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB49",
      "unstructured": "Otwinowski, Z. (1991). Maximum likelihood refinement of heavy atom parameters, in Isomorphous Replacement and Anomalous Scattering, W. Wolf, P.R. Evans, and A.G.W. Leslie, eds. (Warrington, UK: Daresbury Laboratory), pp. 80\u201386."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB50",
      "doi-asserted-by": "crossref",
      "unstructured": "CCP4 (Collaborative Computational Project 4) (1994). The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D 50, 760\u2013763.",
      "DOI": "10.1107/S0907444994003112"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB51",
      "first-page": "34",
      "article-title": "Dm'",
      "volume": "31",
      "author": "Cowtan",
      "year": "1994",
      "journal-title": "Joint CCP4 and ESF-EACBM Newsletter on Protein Crystallography"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB52",
      "doi-asserted-by": "crossref",
      "first-page": "110",
      "DOI": "10.1107/S0108767390010224",
      "article-title": "Improved methods for building protein models in electron density maps and the location of errors in these models",
      "volume": "47",
      "author": "Jones",
      "year": "1991",
      "journal-title": "Acta Crystallogr. A"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB53",
      "doi-asserted-by": "crossref",
      "first-page": "240",
      "DOI": "10.1107/S0907444996012255",
      "article-title": "Refinement of macromolecular structures by the maximum-likelihood method",
      "volume": "53",
      "author": "Murshudov",
      "year": "1997",
      "journal-title": "Acta Cryst. D"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB54",
      "doi-asserted-by": "crossref",
      "first-page": "905",
      "DOI": "10.1107/S0907444998003254",
      "article-title": "Crystallography & NMR system",
      "volume": "54",
      "author": "Br\u00fcnger",
      "year": "1998",
      "journal-title": "Acta Crystallogr. D Biol. Crystallogr"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB55",
      "doi-asserted-by": "crossref",
      "first-page": "1119",
      "DOI": "10.1107/S0907444998007100",
      "article-title": "Databases in protein crystallography",
      "volume": "54",
      "author": "Kleywegt",
      "year": "1998",
      "journal-title": "Acta Crystallogr. D"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB56",
      "doi-asserted-by": "crossref",
      "first-page": "4673",
      "DOI": "10.1093/nar/22.22.4673",
      "article-title": "Clustal w",
      "volume": "22",
      "author": "Thompson",
      "year": "1994",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB57",
      "doi-asserted-by": "crossref",
      "first-page": "15",
      "DOI": "10.1098/rspa.1961.0220",
      "article-title": "The structure of haemoglobin. VIII. A three-dimetional Fourier synthesis at 5.5 \u00c5 resolution",
      "volume": "265",
      "author": "Cullis",
      "year": "1961",
      "journal-title": "Proc. Roy. Soc. London Ser. A"
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB58",
      "doi-asserted-by": "crossref",
      "first-page": "946",
      "DOI": "10.1107/S0021889891004399",
      "article-title": "Molscript",
      "volume": "24",
      "author": "Kraulis",
      "year": "1991",
      "journal-title": "J. Appl. Crystallogr."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB59",
      "doi-asserted-by": "crossref",
      "first-page": "133",
      "DOI": "10.1016/S1093-3263(97)00021-1",
      "article-title": "An extensively modified version of Molscript that includes greatly enhanced coloring capabilities",
      "volume": "15",
      "author": "Esnouf",
      "year": "1997",
      "journal-title": "J. Mol. Graph. Model."
    },
    {
      "key": "10.1016/S0969-2126(00)00533-5_BIB61",
      "series-title": "GRASP",
      "author": "Nicholls",
      "year": "1992"
    }
  ],
  "container-title": "Structure",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0969212600005335?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0969212600005335?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2021,
        5,
        10
      ]
    ],
    "date-time": "2021-05-10T21:56:55Z",
    "timestamp": 1620683815000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0969212600005335"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2000,
        12
      ]
    ]
  },
  "references-count": 60,
  "journal-issue": {
    "issue": "12",
    "published-print": {
      "date-parts": [
        [
          2000,
          12
        ]
      ]
    }
  },
  "alternative-id": [
    "S0969212600005335"
  ],
  "URL": "http://dx.doi.org/10.1016/S0969-2126(00)00533-5",
  "relation": {},
  "ISSN": [
    "0969-2126"
  ],
  "subject": [],
  "container-title-short": "Structure",
  "published": {
    "date-parts": [
      [
        2000,
        12
      ]
    ]
  }
}