DOI: 10.1016/s0962-8924(01)02151-1. Cellular senescence as a tumor-suppressor mechanism

Cellular senescence as a tumor-suppressor mechanism

10.1016/s0962-8924(01)02151-1

Crossref journal-article

Elsevier BV

Trends in Cell Biology (78)

Bibliography

Campisi, J. (2001). Cellular senescence as a tumor-suppressor mechanism. Trends in Cell Biology, 11(11), S27âS31.

Authors 1

Judith Campisi (first)

References 31 Referenced 381

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{'key': '10.1016/S0962-8924(01)02151-1_BIB2', 'first-page': '183', 'article-title': 'Cancer, aging and cellular senescence', 'volume': '14', 'author': 'Campisi', 'year': '2000', 'journal-title': 'In Vivo'} / In Vivo / Cancer, aging and cellular senescence by Campisi (2000)
10.3181/00379727-214-44075 / Proc. Soc. Exp. Biol. Med. / Replicative senescence and cell immortality: The role of telomeres and telomerase by Chiu (1997)
10.1038/35040500 / Nature / Telomere states and cell fates by Blackburn (2000)
10.1074/jbc.M009470200 / J. Biol. Chem. / DNA methyltransferase inhibition in normal human fibroblasts induces a p21-dependent cell cycle arrest by Young (2001)
10.1128/MCB.20.1.273-285.2000 / Mol. Cell. Biol. / Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14/ARF tumor suppressor by Dimri (2000)
10.1016/S0092-8674(00)81902-9 / Cell / Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a by Serrano (1997)
10.1101/gad.12.19.2997 / Genes Dev. / Senescence of human fibroblasts induced by oncogenic raf by Zhu (1998)
10.1101/gad.12.19.3008 / Genes Dev. / Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling by Lin (1998)
{'key': '10.1016/S0962-8924(01)02151-1_BIB10', 'first-page': '1539', 'article-title': 'Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts', 'volume': '59', 'author': 'Wei', 'year': '1999', 'journal-title': 'Cancer Res.'} / Cancer Res. / Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts by Wei (1999)
10.1006/excr.2001.5182 / Exp. Cell Res. / Uncoupling the senescent phenotype from telomere shortening in hydrogen peroxide treated fibroblasts by Chen (2001)
10.1667/0033-7587(2001)155[0248:RISLGA]2.0.CO;2 / Radiat. Res. / Radiation-induced senescence-like growth arrest requires TP53 function but not telomere shortening by Susuki (2001)
10.1016/S0531-5565(00)00083-8 / Exp. Gerontol. / Tumor suppressors and oncogenes in cellular senescence by Bringold (2000)
10.1016/S0955-0674(00)00155-1 / Curr. Opin. Cell Biol. / Genes involved in senescence and immortalization by Lundberg (2000)
10.1046/j.1432-1327.2001.02228.x / Eur. J. Biochem. / Regulation of cellular senescence by p53 by Itahana (2001)
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10.1038/35021000 / Nature / PML regulates p53 acetylation and premature senescence induced by oncogenic Ras by Pearson (2000)
10.1101/gad.14.16.2015 / Genes Dev. / PML is induced by oncogenic ras and promotes premature senescence by Ferbeyre (2000)
10.1006/excr.1998.4345 / Exp. Cell Res. / Two posttranscriptional pathways that regulate p21(Cip1/Waf1/Sdi1) are identified by HPV16-E6 interaction and correlate with life span and cellular senescence by Burkhart (1999)
10.1038/35059131 / Nature / Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence by Ohtani (2001)
10.1038/16476 / Nature / The oncogene and Polycomb-group bmi-1 regulates cell proliferation and senescence through the ink4a locus by Jacobs (1999)
10.1038/sj.onc.1202954 / Oncogene / mdm2: a bridge over two tumour suppressors, p53 and Rb by Yap (1999)
10.1016/S0960-9822(98)70137-X / Curr. Biol. / Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts by McConnell (1998)
10.1038/sj.onc.1202573 / Oncogene / Mouse models in tumor suppression by Ghebranious (1998)
10.1038/sj.onc.1204312 / Oncogene / Reducing mammary cancer risk through premature stem cell senescence by Boulanger (2001)
10.1002/(SICI)1098-2744(199701)18:1<7::AID-MC2>3.0.CO;2-F / Mol. Carcinog. / Extended life span and immortalization of human fibroblasts induced by X-ray irradiation by Tsutsui (1997)
Krtolica, A. et al. Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging. Proc. Natl. Acad. Sci. U. S. A. (in press) (10.1073/pnas.211053698)
10.1034/j.1600-0560.2001.280201.x / J. Cutaneous Pathol. / Creation of psoriatic plaques: the ultimate tumor suppressor pathway by Nickoloff (2001)
10.1016/S0960-9822(99)80420-5 / Curr. Biol. / Microarray analysis of replicative senescence by Shelton (1999)
10.1038/sj.onc.1202303 / Oncogene / Stress-induced secretion of growth inhibitors: a novel tumor suppressor function of p53 by Komarova (1998)
10.1073/pnas.97.8.4291 / Proc. Natl. Acad. Sci. U.S.A. / Effects of p21/Waf1/Co1/Sdi1 on cellular gene expression: Implications for carcinogenesis, senescence and age-related diseases by Chang (2000)

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 9:11 a.m.)
Deposited	2 years, 4 months ago (April 8, 2023, 10:29 a.m.)
Indexed	9 minutes ago (Sept. 4, 2025, 2:39 a.m.)
Issued	23 years, 10 months ago (Nov. 1, 2001)
Published	23 years, 10 months ago (Nov. 1, 2001)
Published Print	23 years, 10 months ago (Nov. 1, 2001)

Funders 0

None

BibTeX

@article{Campisi_2001, title={Cellular senescence as a tumor-suppressor mechanism}, volume={11}, ISSN={0962-8924}, url={http://dx.doi.org/10.1016/s0962-8924(01)02151-1}, DOI={10.1016/s0962-8924(01)02151-1}, number={11}, journal={Trends in Cell Biology}, publisher={Elsevier BV}, author={Campisi, Judith}, year={2001}, month=nov, pages={S27–S31} }

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