DOI: 10.1016/s0960-9822(02)00515-8. E2F-1 but not E2F-4 can overcome p16-induced G1 cell-cycle arrest

E2F-1 but not E2F-4 can overcome p16-induced G1 cell-cycle arrest

10.1016/s0960-9822(02)00515-8

Crossref journal-article

Elsevier BV

Current Biology (78)

Bibliography

Mann, D. J., & Jones, N. C. (1996). E2F-1 but not E2F-4 can overcome p16-induced G1 cell-cycle arrest. Current Biology, 6(4), 474â483.

Authors 2

David J. Mann (first)
Nic C. Jones (additional)

References 67 Referenced 54

10.1016/0092-8674(93)90636-5 / Cell / Mammalian G1 cyclins by Sherr (1993)
10.1016/0092-8674(95)90385-2 / Cell / The retinoblastoma protein and cell cycle control by Weinberg (1995)
10.1101/gad.7.3.331 / Genes Dev / Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase, CDK4 by Kato (1993)
10.1016/0092-8674(93)90136-E / Cell / Functional interactions of the retinoblastoma protein with mammalian G1 cyclins by Ewen (1993)
10.1016/0092-8674(91)90557-F / Cell / The E2F transcription factor is a cellular target for the Rb protein by Chellappan (1991)
10.1016/0092-8674(92)90107-N / Cell / A cDNA encoding a pRb binding protein with the properties of transcription factor E2F by Helin (1992)
10.1128/MCB.12.8.3431 / Mol Cell Biol / Transcriptional repression of the E2-containing promoters EIIaE, c-myc and RB1 by the product of the RB1 gene by Hamel (1992)
10.1101/gad.6.2.177 / Genes Dev / The interaction of pRb and E2F inhibits the transcriptional activity of E2F by Heibert (1992)
10.1002/j.1460-2075.1992.tb05325.x / EMBO J / Adenovirus E1A prevents the retinoblastoma gene product from repressing the activity of a cellular transcription factor by Zamanian (1992)
10.1128/MCB.13.10.6501 / Mol Cell Biol / Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein by Helin (1993)
10.1126/science.1411535 / Science / E2F: a link between the Rb tumor suppressor protein and viral oncoproteins by Nevins (1992)
10.1128/MCB.15.5.2536 / Mol Cell Biol / In vivo association of E2F and DP family proteins by Wu (1995)
10.1073/pnas.90.8.3525 / Proc Natl Acad Sci USA / Transcription factor E2F binds DNA as a heterodimer by Huber (1993)
{'key': '10.1016/S0960-9822(02)00515-8_BIB14', 'first-page': '2085', 'article-title': 'Cloning and characterisation of human DP-2, a novel dimerisation partner of E2F', 'volume': '10', 'author': 'Zhang', 'year': '1995', 'journal-title': 'Oncogene'} / Oncogene / Cloning and characterisation of human DP-2, a novel dimerisation partner of E2F by Zhang (1995)
10.1038/362083a0 / Nature / A new component of the transcription factor DRTF1/E2F by Girling (1993)
10.1101/gad.7.10.1850 / Genes Dev / Heterodimerisation of the transcription factors E2F-1 and DP-1 leads to cooperative transactivation by Helin (1993)
{'key': '10.1016/S0960-9822(02)00515-8_BIB17', 'first-page': '1437', 'article-title': 'A new member of the DP family, DP-3, with distinct protein products suggests a regulatory role for alternative splicing in the cell cycle transcription factor DRTF1/E2F', 'volume': '11', 'author': 'Ormondroyd', 'year': '1995', 'journal-title': 'Oncogene'} / Oncogene / A new member of the DP family, DP-3, with distinct protein products suggests a regulatory role for alternative splicing in the cell cycle transcription factor DRTF1/E2F by Ormondroyd (1995)
10.1016/0092-8674(92)90108-O / Cell / Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties by Kaelin (1992)
10.1128/MCB.12.12.5620 / Mol Cell Biol / Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F by Shan (1992)
10.1128/MCB.13.12.7802 / Mol Cell Biol / Cloning and characterisation of E2F-2, a novel protein with the biochemical properties of transcription factor E2F by Ivey-Hoyle (1993)
10.1128/MCB.13.12.7813 / Mol Cell Biol / The retinoblastoma protein binds to a family of E2F transcription factors by Lees (1993)
10.1101/gad.8.22.2680 / Genes Dev / E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo by Beijersbergen (1994)
10.1101/gad.8.22.2665 / Genes Dev / E2F-4, a new member of the E2F transcription factor, interacts with p107 by Ginsberg (1994)
10.1128/MCB.15.6.3082 / Mol Cell Biol / E2F-5, a new E2F family member that interacts with p130 in vivo by Hijmans (1995)
10.1128/JVI.67.12.7641-7647.1993 / J Virol / Analysis of p107 associated proteins: p107 associates with a form of E2F that differs from pRb associated E2F-1 by Dyson (1993)
10.1101/gad.9.10.1149 / Genes Dev / Inhibitors of mammalian G1 cyclin-dependent kinases by Sherr (1995)
10.1038/366704a0 / Nature / A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/cdk4 by Serrano (1993)
10.1101/gad.8.24.2939 / Genes Dev / Growth suppression by p18, a p16- and p14-related cdk6 inhibitor, correlates with wild type pRb function by Guan (1994)
10.1038/371257a0 / Nature / p15INK4b is a potential effector of cell cycle arrest mediated by TGF-β by Hannon (1994)
10.1128/MCB.15.5.2682 / Mol Cell Biol / Identification of human/mouse p19, a novel cdk4/cdk6 inhibitor with homology to p16 by Chan (1995)
10.1128/MCB.15.5.2672 / Mol Cell Biol / Novel INK4 proteins, p18 and p19, are specific inhibitors of cyclin D-dependent kinases cdk4 and cdk6 by Hirai (1995)
10.1002/j.1460-2075.1995.tb07026.x / EMBO J / Lack of cyclin D–cdk complexes in Rb-negative cells correlates with high levels of p16 tumor suppressor gene product by Parry (1995)
10.1016/0092-8674(93)90500-P / Cell / WAF1, a potential mediator of p53 tumor suppression by El-Diery (1993)
10.1091/mbc.6.4.387 / Mol Biol Cell / Inhibition of cyclin-dependent kinases by p21 by Harper (1995)
10.1038/366701a0 / Nature / p21 is a universal inhibitor of cyclin kinases by Xiong (1993)
10.1101/gad.8.1.9 / Genes Dev / p27KIP1, a cyclin-cdk inhibitor, links transforming growth factor-β and contact inhibition with cell cycle arrest by Polyak (1994)
10.1016/0092-8674(94)90572-X / Cell / Cloning of p27KIP1, a cyclin-dependent kinase inhibitor and potential mediator of extracellular mitogenic signals by Polyak (1994)
10.1016/0092-8674(94)90573-8 / Cell / p27, a novel inhibitor of G1 cyclin/cdk protein kinase activity, is related to p21 by Toyoshima (1994)
10.1101/gad.9.6.639 / Genes Dev / Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution by Lee (1995)
10.1101/gad.9.6.650 / Genes Dev / p57KIP2, a structurally distinct member of the p21CIP1cdk inhibitor family, is a candidate tumor suppressor gene by Matsuoka (1995)
10.1091/mbc.6.4.387 / Mol Biol Cell / Inhibition of cyclin-dependent kinases by p21 by Harper (1995)
10.1038/375503a0 / Nature / Retinoblastoma protein-dependent cell cycle inhibition by the tumor suppressor p16 by Lukas (1995)
10.1002/j.1460-2075.1987.tb02470.x / EMBO J / Mutational analysis of the adenovirus E1a gene: the role of transcriptional regulation in transformation by Schneider (1987)
10.1128/MCB.10.12.6664 / Mol Cell Biol / Maintenance of cellular proliferation by adenovirus early region 1A in fibroblasts conditionally immortalized by using simian virus 40 large T antigen requires conserved region 1 by Riley (1990)
10.1128/JVI.67.5.2521-2528.1993 / J Virol / Human papillomavirus type 16 E7 associates with a histone H1 kinase and with p107 through sequences necessary for transformation by Davies (1993)
10.1002/j.1460-2075.1994.tb06330.x / EMBO J / HPV16 E7 oncoprotein deregulates B-myb expression: correlation with targeting of p107/E2F complexes by Lam (1994)
10.1128/MCB.13.10.6314 / Mol Cell Biol / A genetic analysis of the E2F-1 gene distinguishes regulation by Rb, p107 and adenovirus E4 by Cress (1993)
10.1091/mbc.4.9.897 / Mol Biol Cell / Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes by Zhang (1993)
10.1073/pnas.91.18.8655 / Proc Natl Acad Sci USA / Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by DNA polymerase δ holoenzyme by Flores-Rozas (1994)
10.1038/369574a0 / Nature / The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA by Waga (1994)
10.1128/MCB.15.8.4215 / Mol Cell Biol / Cellular targets for activation by the E2F-1 transcription factor include DNA synthesis- and G1/S-regulatory genes by DeGregori (1995)
10.1128/MCB.15.7.3463 / Mol Cell Biol / Different roles for cyclins D1 and E in regulation of the G1 to S transition by Resnitzky (1995)
10.1083/jcb.125.3.625 / J Cell Biol / DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function by Lukas (1994)
{'key': '10.1016/S0960-9822(02)00515-8_BIB54', 'first-page': '2663', 'article-title': 'Differential expression and regulation of cyclin D1 protein in normal and tumor human cells: association with Cdk4 is required for cyclin D1 function in G1 progression', 'volume': '9', 'author': 'Tam', 'year': '1994', 'journal-title': 'Oncogene'} / Oncogene / Differential expression and regulation of cyclin D1 protein in normal and tumor human cells: association with Cdk4 is required for cyclin D1 function in G1 progression by Tam (1994)
10.1128/MCB.15.5.2612 / Mol Cell Biol / Human cyclin E, a nuclear protein essential for the G1 to S transition by Ohtsubo (1995)
10.1101/gad.9.23.2873 / Genes Dev / E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity by DeGregori (1995)
10.1016/0092-8674(94)90582-7 / Cell / Negative regulation of the growth promoting transcription factor E2F-1 by a stably bound cyclin-A-dependent protein kinase by Krek (1994)
10.1101/gad.8.15.1772 / Genes Dev / Differential regulation of E2F transactivation by cyclin/cdk2 complexes by Dynlacht (1994)
10.1126/science.7652577 / Science / A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma by Wölfel (1995)
{'key': '10.1016/S0960-9822(02)00515-8_BIB60', 'first-page': 'in press', 'article-title': 'Genetic alterations of cyclins, cyclin dependent kinases and cdk-inhibitors in human cancer', 'volume': '68', 'author': 'Hall', 'year': '1995', 'journal-title': 'Adv Cancer Res'} / Adv Cancer Res / Genetic alterations of cyclins, cyclin dependent kinases and cdk-inhibitors in human cancer by Hall (1995)
10.1128/MCB.9.4.1672 / Mol Cell Biol / Cell lines established by a temperature-sensitive simian virus 40 large-T-antigen gene are growth restricted at the nonpermissive temperature by Jat (1989)
10.1073/pnas.92.5.1357 / Proc Natl Acad Sci USA / Multiple members of the E2F transcription factor family are the products of oncogenes by Xu (1995)
{'key': '10.1016/S0960-9822(02)00515-8_BIB63', 'first-page': '106', 'article-title': 'A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cells', 'volume': '18', 'author': 'Morganstern', 'year': '1990', 'journal-title': 'Nucleic Acids Res'} / Nucleic Acids Res / A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cells by Morganstern (1990)
{'key': '10.1016/S0960-9822(02)00515-8_BIB64', 'first-page': '2019', 'article-title': 'Differential regulation of three members of the ATF/Creb family of DNA-binding proteins', 'volume': '6', 'author': 'Flint', 'year': '1991', 'journal-title': 'Oncogene'} / Oncogene / Differential regulation of three members of the ATF/Creb family of DNA-binding proteins by Flint (1991)
10.1016/0003-2697(86)90180-6 / Anal Biochem / A nonchromatographic assay for expression of the chloramphenicol acetyltransferase gene in eucaryotic cells by Sleigh (1986)
10.1016/0092-8674(88)90393-5 / Cell / Transcriptional activation by the SV40 AP-1 recognition element in yeast is mediated by a factor similar to AP-1 that is distinct from GCN4 by Harshman (1988)
{'key': '10.1016/S0960-9822(02)00515-8_BIB67', 'series-title': 'Antibodies,', 'author': 'Harlow', 'year': '1988'} / Antibodies, by Harlow (1988)

Dates

Type	When
Created	21 years, 4 months ago (April 13, 2004, 5:30 a.m.)
Deposited	5 years, 4 months ago (March 31, 2020, 7:51 p.m.)
Indexed	1 year, 3 months ago (May 12, 2024, 5:20 p.m.)
Issued	29 years, 4 months ago (April 1, 1996)
Published	29 years, 4 months ago (April 1, 1996)
Published Print	29 years, 4 months ago (April 1, 1996)

Funders 0

None

BibTeX

@article{Mann_1996, title={E2F-1 but not E2F-4 can overcome p16-induced G1 cell-cycle arrest}, volume={6}, ISSN={0960-9822}, url={http://dx.doi.org/10.1016/s0960-9822(02)00515-8}, DOI={10.1016/s0960-9822(02)00515-8}, number={4}, journal={Current Biology}, publisher={Elsevier BV}, author={Mann, David J. and Jones, Nic C.}, year={1996}, month=apr, pages={474–483} }

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      "author": "Schneider",
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      "author": "Riley",
      "year": "1990",
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      "author": "Davies",
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      "volume": "13",
      "author": "Lam",
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