Crossref journal-article
Elsevier BV
Current Biology (78)
Bibliography

Smith, F. D., & Scott, J. D. (2002). Signaling Complexes: Junctions on the Intracellular Information Super Highway. Current Biology, 12(1), R32–R40.

Authors 2
  1. F.Donelson Smith (first)
  2. John D Scott (additional)
References 91 Referenced 100
  1. 10.1126/science.278.5346.2075 / Science / Signaling through scaffold, anchoring, and adaptor proteins by Pawson (1997)
  2. 10.1016/S1040-7952(97)80007-9 / Adv. Second Messenger Phosphoprotein Res. / Specificity in protein-tyrosine kinase signaling by Cantley (1997)
  3. 10.1016/S0955-0674(99)00078-2 / Curr. Opin. Cell Biol. / Signal transduction: hanging on a scaffold by Burack (2000)
  4. 10.1016/S0092-8674(00)81688-8 / Cell / Signaling — 2000 and beyond by Hunter (2000)
  5. 10.1101/gad.14.9.1027 / Genes Dev. / Protein–protein interactions define specificity in signal transduction by Pawson (2000)
  6. 10.1016/S0092-8674(00)00112-4 / Cell / Signaling networks: the origins of cellular multitasking by Jordan (2000)
  7. {'key': '10.1016/S0960-9822(01)00646-7_BIB7', 'first-page': '312', 'article-title': 'More on target with protein phosphorylation: conferring specificity by location', 'volume': '21', 'author': 'Faux', 'year': '1996', 'journal-title': 'Trends Biochem. Sci.'} / Trends Biochem. Sci. / More on target with protein phosphorylation: conferring specificity by location by Faux (1996)
  8. 10.1128/MMBR.62.4.1264-1300.1998 / Microbiol. Mol. Biol. Rev. / MAP kinase pathways in the yeast Saccharomyces cerevisiae by Gustin (1998)
  9. 10.1093/genetics/138.3.609 / Genetics / Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade by Printen (1994)
  10. 10.1016/0092-8674(94)90427-8 / Cell / Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae by Choi (1994)
  11. 10.1016/S0962-8924(00)89055-8 / Trends Cell Biol. / Ste5: a meeting place for MAP kinases and their associates by Elion (1995)
  12. 10.1016/S0960-9822(01)00370-0 / Curr. Biol. / MAPK specificity in the yeast pheromone response independent of transcriptional activation by Breitkreutz (2001)
  13. 10.1016/S1097-2765(01)00322-7 / Mol. Cell / Specificity of MAP kinase signaling in yeast differentiation involves transient versus sustained MAPK activation by Sabbagh (2001)
  14. 10.1126/science.281.5383.1668 / Science / MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade by Schaeffer (1998)
  15. 10.1126/science.277.5326.693 / Science / A cytoplasmic inhibitor of the JNK signal transduction pathway by Dickens (1997)
  16. 10.1126/science.281.5383.1671 / Science / A mammalian scaffold complex that selectively mediates MAP kinase activation by Whitmarsh (1998)
  17. 10.1128/MCB.20.3.1030-1043.2000 / Mol. Cell. Biol. / Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3 by Kelkar (2000)
  18. 10.1093/emboj/20.13.3447 / EMBO J. / Mixed lineage kinase-dependent JNK activation is governed by interactions of scaffold protein JIP with MAPK module components by Nihalani (2001)
  19. 10.1128/MCB.19.1.229 / Mol. Cell. Biol. / Identification of constitutive and ras-inducible phosphorylation sites of KSR: implications for 14-3-3 binding, mitogen-activated protein kinase binding, and KSR overexpression by Cacace (1999)
  20. 10.1242/jcs.114.9.1609 / J. Cell Sci. / KSR: a MAPK scaffold of the Ras pathway? by Morrison (2001)
  21. 10.1016/S0955-0674(99)00075-7 / Curr. Opin. Cell Biol. / Protein phosphatases and the regulation of mitogen-activated protein kinase signalling by Keyse (2000)
  22. {'key': '10.1016/S0960-9822(01)00646-7_BIB22', 'first-page': '415', 'article-title': 'The interaction of SV40 small tumor antigen with protein phosphatase 2A', 'volume': '64', 'author': 'Sontag', 'year': '1993', 'journal-title': 'Cell'} / Cell / The interaction of SV40 small tumor antigen with protein phosphatase 2A by Sontag (1993)
  23. 10.1016/S0962-8924(99)01558-5 / Trends Cell Biol. / AKAPs: from structure to function by Colledge (1999)
  24. {'key': '10.1016/S0960-9822(01)00646-7_BIB24', 'first-page': 'D678', 'article-title': 'Specificity in the cAMP/PKA signaling pathway. Differential expression, regulation, and subcellular localization of subunits of PKA', 'volume': '5', 'author': 'Skalhegg', 'year': '2000', 'journal-title': 'Front. Biosci.'} / Front. Biosci. / Specificity in the cAMP/PKA signaling pathway. Differential expression, regulation, and subcellular localization of subunits of PKA by Skalhegg (2000)
  25. 10.1038/6663 / Nat. Struct. Biol. / The molecular basis for protein kinase A anchoring revealed by solution NMR by Newlon (1999)
  26. 10.1126/science.271.5255.1589 / Science / Coordination of three signaling enzymes by AKAP79, a mammalian scaffold protein by Klauck (1996)
  27. 10.1038/368853a0 / Nature / Anchoring of protein kinase A is required for modulation of AMPA/kainate receptors on hippocampal neurons by Rosenmund (1994)
  28. 10.1016/S0896-6273(00)00013-1 / Neuron / Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex by Colledge (2000)
  29. 10.1016/S0896-6273(00)80633-9 / Neuron / Involvement of a postsynaptic protein kinase A substrate in the expression of homosynaptic long-term depression by Kameyama (1998)
  30. 10.1038/35016089 / Nature / Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity by Lee (2000)
  31. 10.1523/JNEUROSCI.20-01-00089.2000 / J. Neurosci. / Control of GluR1 AMPA receptor function by cAMP-dependent protein kinase by Banke (2000)
  32. 10.1074/jbc.274.8.4934 / J. Biol. Chem. / Protein kinase A anchoring proteins are required for vasopressin-mediated translocation of aquaporin-2 into cell membranes of renal principal cells by Klussmann (1999)
  33. 10.1152/ajpcell.2000.278.2.C417 / Am. J. Physiol. Cell Physiol. / PKA holoenzyme is functionally coupled to CFTR by AKAPs by Huang (2000)
  34. 10.1523/JNEUROSCI.18-06-02017.1998 / J. Neurosci. / Yotiao, a novel protein of neuromuscular junction and brain that interacts with specific splice variants of NMDA receptor subunit NR1 by Lin (1998)
  35. 10.1126/science.285.5424.93 / Science / Regulation of NMDA receptors by an associated phosphatase-kinase signaling complex by Westphal (1999)
  36. 10.1016/S0896-6273(00)80059-8 / Neuron / β-adrenergic regulation of synaptic NMDA receptors by cAMP-dependent protein kinase by Raman (1996)
  37. 10.1038/369230a0 / Nature / Regulation of NMDA receptors in cultured hippocampal neurons by protein phosphatases 1 and 2A by Wang (1994)
  38. 10.1523/JNEUROSCI.18-24-10297.1998 / J. Neurosci. / A dopamine/D1 receptor/protein kinase A/dopamine- and cAMP-regulated phosphoprotein (Mr 32 kDa)/protein phosphatase-1 pathway regulates dephosphorylation of the NMDA receptor by Snyder (1998)
  39. 10.1074/jbc.M005285200 / J. Biol. Chem. / Association of immature hypo-phosphorylated protein kinase C epsilon with an anchoring protein CG-NAP by Takahashi (2000)
  40. 10.1242/jcs.114.8.1431 / J. Cell Sci. / AKAP signaling complexes at the cytoskeleton by Diviani (2001)
  41. 10.1016/S0960-9822(99)80141-9 / Curr. Biol. / Association of the type 1 protein phosphatase PP1 with the A-kinase anchoring protein AKAP220 by Schillace (1999)
  42. 10.1083/jcb.150.6.1251 / J. Cell Biol. / Recruitment of protein phosphatase 1 to the nuclear envelope by A-kinase anchoring protein AKAP149 is a prerequisite for nuclear lamina assembly by Steen (2000)
  43. 10.1093/emboj/20.8.1921 / EMBO J. / mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module by Dodge (2001)
  44. 10.1074/jbc.C000911200 / J. Biol. Chem. / Phosphodiesterase 4D and protein kinase a type II constitute a signaling unit in the centrosomal area by Tasken (2001)
  45. 10.1042/bj3280549 / Biochem. J. / Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3 by Huston (1997)
  46. 10.1074/jbc.271.28.16526 / J. Biol. Chem. / Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase by Sette (1996)
  47. 10.1016/S0092-8674(00)80847-8 / Cell / PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts by Marx (2000)
  48. 10.1161/01.RES.88.3.291 / Circ. Res. / AKAP-mediated targeting of protein kinase a regulates contractility in cardiac myocytes by Fink (2001)
  49. 10.1161/01.CIR.101.12.1459 / Circulation / Regulation of PKA binding to AKAPs in the heart: alterations in human heart failure by Zakhary (2000)
  50. {'key': '10.1016/S0960-9822(01)00646-7_BIB50', 'first-page': '1', 'article-title': 'Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling', 'volume': '53', 'author': 'Ferguson', 'year': '2001', 'journal-title': 'Pharmacol. Rev.'} / Pharmacol. Rev. / Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling by Ferguson (2001)
  51. 10.1074/jbc.275.13.9572 / J. Biol. Chem. / The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor by Maudsley (2000)
  52. 10.1073/pnas.041604898 / Proc. Natl. Acad. Sci. U.S.A. / Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds by Luttrell (2001)
  53. 10.1126/science.283.5402.655 / Science / Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes by Luttrell (1999)
  54. 10.1083/jcb.148.6.1267 / J. Cell Biol. / β-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2 by DeFea (2000)
  55. 10.1126/science.290.5496.1574 / Science / β-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3 by McDonald (2000)
  56. 10.1016/S0092-8674(00)81978-9 / Cell / Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade by Mahanty (1999)
  57. 10.1016/S1369-5274(00)00143-0 / Curr. Opin. Microbiol. / Pheromone response, mating and cell biology by Elion (2000)
  58. 10.1038/36362 / Nature / Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A by Daaka (1997)
  59. 10.1074/jbc.M104434200 / J. Biol. Chem. / Protein kinase A-mediated phosphorylation of serine 357 of the mouse prostacyclin receptor regulates its coupling to G(s), to G(i), and to G(q)-coupled effector signaling by Lawler (2001)
  60. 10.1074/jbc.274.3.1588 / J. Biol. Chem. / Dynamic complexes of beta2-adrenergic receptors with protein kinases and phosphatases and the role of gravin by Shih (1999)
  61. 10.1016/S0960-9822(00)00419-X / Curr. Biol. / Assembly of an AKAP/beta2-adrenergic receptor signaling complex facilitates receptor phosphorylation and signaling by Fraser (2000)
  62. 10.1074/jbc.275.25.19025 / J. Biol. Chem. / Gravin-mediated formation of signaling complexes in beta 2-adrenergic receptor desensitization and resensitization by Lin (2000)
  63. 10.1074/jbc.M009130200 / J. Biol. Chem. / Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by Protein Kinase A and its anchoring protein AKAP79 by Cong (2001)
  64. 10.1126/science.1058040 / Science / The sequence of the human genome by Venter (2001)
  65. 10.1038/35057062 / Nature / Initial sequencing and analysis of the human genome by Lander (2001)
  66. 10.1083/jcb.145.5.951 / J. Cell Biol. / NH2-Terminal targeting motifs direct dual specificity A-kinase- anchoring protein 1 (D-AKAP1) to either mitochondria or endoplasmic reticulum by Huang (1999)
  67. 10.1083/jcb.147.7.1481 / J. Cell Biol. / Alternative splicing regulates the subcellular localization of A-kinase anchoring protein 18 isoforms by Trotter (1999)
  68. 10.1242/jcs.112.16.2725 / J. Cell Sci. / mAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes by Kapiloff (1999)
  69. 10.1242/jcs.114.17.3167 / J. Cell Sci. / mAKAP and the ryanodine receptor are part of a multi-component signaling complex on the cardiomyocyte nuclear envelope by Kapiloff (2001)
  70. 10.1016/S0968-0004(00)01714-X / Trends Biochem. Sci. / Observing proteins in their natural habitat: the living cell by Bastiaens (2000)
  71. 10.1083/jcb.140.3.485 / J. Cell Biol. / Green fluorescent protein (GFP)-tagged cysteine-rich domains from protein kinase C as fluorescent indicators for diacylglycerol signaling in living cells by Oancea (1998)
  72. 10.1016/S0960-9822(99)80192-4 / Curr. Biol. / Akt/PKB localisation and 3′ phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction by Watton (1999)
  73. 10.1083/jcb.147.2.447 / J. Cell Biol. / Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor by Janes (1999)
  74. 10.1016/S0092-8674(00)00109-4 / Cell / Translocation and reversible localization of signaling proteins: a dynamic future for signal transduction by Teruel (2000)
  75. 10.1126/science.290.5496.1567 / Science / Quantitative imaging of lateral ErbB1 receptor signal propagation in the plasma membrane by Verveer (2000)
  76. 10.1016/S0092-8674(00)81064-8 / Cell / Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity by Chen (1996)
  77. 10.1093/emboj/16.21.6486 / EMBO J. / Inhibition of NF-κB cellular function via specific targeting of the I-κB-ubiquitin ligase by Yaron (1997)
  78. 10.1146/annurev.immunol.18.1.621 / Annu. Rev. Immunol. / Phosphorylation meets ubiquitination: the control of NF-κB activity by Karin (2000)
  79. 10.1073/pnas.90.16.7436 / Proc. Natl. Acad. Sci. U.S.A. / Regulatory subunits of cAMP-dependent protein kinases are degraded after conjugation to ubiquitin: a molecular mechanism underlying long-term synaptic plasticity by Hegde (1993)
  80. 10.1016/S0896-6273(00)80686-8 / Neuron / Mechanisms for generating the autonomous cAMP-dependent protein kinase required for long-term facilitation in Aplysia by Chain (1999)
  81. 10.1016/S0092-8674(00)80982-4 / Cell / Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis by Hicke (1996)
  82. 10.1038/35056583 / Nat. Rev. Mol. Cell. Biol. / Protein regulation by monoubiquitin by Hicke (2001)
  83. 10.1146/annurev.biochem.70.1.703 / Annu. Rev. Biochem. / Regulation of G protein-initiated signal transduction in yeast: paradigms and principles by Dohlman (2001)
  84. 10.1016/S1097-2765(00)80231-2 / Mol. Cell / Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1 by Levkowitz (1999)
  85. 10.1074/jbc.M102641200 / J. Biol. Chem. / Cbl-b-dependent coordinated degradation of the epidermal growth factor receptor signaling complex by Ettenberg (2001)
  86. 10.1126/science.1063866 / Science / Regulation of receptor fate by ubiquitination of activated β2-adrenergic receptor and β-arrestin by Shenoy (2001)
  87. 10.1074/jbc.C100527200 / J. Biol. Chem. / Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting by Marchese (2000)
  88. 10.1038/35001009 / Nature / A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae by Uetz (2000)
  89. 10.1073/pnas.061034498 / Proc. Natl. Acad. Sci. U.S.A. / A comprehensive two-hybrid analysis to explore the yeast protein interactome by Ito (2001)
  90. 10.1038/35078107 / Nature / Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells by Elbashir (2001)
  91. 10.1016/S0014-5793(00)01773-7 / FEBS Lett. / Functional genomics by mass spectrometry by Andersen (2000)
Dates
Type When
Created 23 years, 1 month ago (July 25, 2002, 10:27 a.m.)
Deposited 1 year, 3 months ago (May 6, 2024, 11:27 a.m.)
Indexed 1 month, 4 weeks ago (July 2, 2025, 3:07 p.m.)
Issued 23 years, 7 months ago (Jan. 1, 2002)
Published 23 years, 7 months ago (Jan. 1, 2002)
Published Print 23 years, 7 months ago (Jan. 1, 2002)
Funders 0

None

@article{Smith_2002, title={Signaling Complexes: Junctions on the Intracellular Information Super Highway}, volume={12}, ISSN={0960-9822}, url={http://dx.doi.org/10.1016/s0960-9822(01)00646-7}, DOI={10.1016/s0960-9822(01)00646-7}, number={1}, journal={Current Biology}, publisher={Elsevier BV}, author={Smith, F.Donelson and Scott, John D}, year={2002}, month=jan, pages={R32–R40} }