DOI: 10.1016/s0959-440x(99)00043-3. Protein folding mechanisms: new methods and emerging ideas

Protein folding mechanisms: new methods and emerging ideas

10.1016/s0959-440x(99)00043-3

Crossref journal-article

Elsevier BV

Current Opinion in Structural Biology (78)

Bibliography

Brockwell, D. J., Smith, D. A., & Radford, S. E. (2000). Protein folding mechanisms: new methods and emerging ideas. Current Opinion in Structural Biology, 10(1), 16â25.

Authors 3

David J Brockwell (first)
D Alastair Smith (additional)
Sheena E Radford (additional)

References 82 Referenced 108

10.1016/S0959-440X(99)80012-8 / Curr Opin Struct Biol / The fundamentals of protein folding: bringing together theory and experiment by Dobson (1999)
10.1016/S0959-440X(99)80027-X / Curr Opin Struct Biol / Matching theory and experiment in protein folding by Alm (1999)
10.1096/fasebj.10.1.8566543 / FASEB J / The denatured state (the other half of the folding equation) and its role in protein stability by Shortle (1996)
10.1038/739 / Nat Struct Biol / Equilibrium NMR studies of unfolded and partially folded proteins by Dyson (1998)
10.1006/jmbi.1999.2722 / J Mol Biol / Side-chain conformations in an unfolded protein: χ1 distributions in denatured hen lysozyme determined by heteronuclear 13C, 15N NMR spectroscopy by Hennig (1999)
10.1021/bi970049q / Biochemistry / Structural and dynamical properties of a denatured protein. Heteronuclear 3D NMR experiments and theoretical simulations of lysozyme in 8 M urea by Schwalbe (1997)
10.1038/6692 / Nat Struct Biol / Hydration of denatured and molten globule proteins by Denisov (1999)
10.1006/jmbi.1997.0953 / J Mol Biol / Characterization of long-range structure in the denatured state of staphylococcal nuclease. II. Distance restraints from paramagnetic relaxation and calculation of an ensemble of structures by Gillespie (1997)
10.1038/12338 / Nat Struct Biol / A model of the changes in the denatured state structure underlying m value effects in staphylococcal nuclease by Wrabl (1999)
10.1006/jmbi.1999.2769 / J Mol Biol / NOE data demonstrating a compact unfolded state for an SH3 domain under non-denaturing conditions by Mok (1999)
10.1038/1412 / Nat Struct Biol / Important role of hydrogen bonds in the structurally polarized transition state for folding of the src SH3 domain by Grantcharova (1998)
10.1038/1418 / Nat Struct Biol / Obligatory steps in protein folding and the conformational diversity of the transition state by Martinez (1998)
10.1006/jmbi.1998.2072 / J Mol Biol / Prediction and structural characterization of an independently folding substructure in the src SH3 domain by Yi (1998)
10.1038/7616 / Nat Struct Biol / Acceleration of the folding of acylphosphatase by stabilization of local secondary structure by Chiti (1999)
10.1006/jmbi.1998.2158 / J Mol Biol / Structure of the transition state in the folding process of human procarboxypeptidase A2 activation domain by Villegas (1998)
10.1006/jmbi.1998.2229 / J Mol Biol / High populations of non-native structures in the denatured state are compatible with the formation of the native folded state by Blanco (1998)
10.1006/jmbi.1998.2273 / J Mol Biol / Effect of H helix destabilizing mutations on the kinetic and equilibrium folding of apomyoglobin by Cavagnero (1999)
10.1016/S1359-0278(98)00033-9 / Fold Des / How do small single-domain proteins fold? by Jackson (1998)
10.1021/bi9817820 / Biochemistry / Effects of core mutations on the folding of a β-sheet protein: implications for backbone organization in the I-state by Lorch (1999)
10.1006/jmbi.1996.0678 / J Mol Biol / The burst-phase intermediate in the refolding of β-lactoglobulin studied by stopped-flow circular dichroism and absorption spectroscopy by Kuwajima (1996)
10.1021/jp990851x / J Phys Chem B / The thermodynamics and kinetics of protein folding: a lattice model analysis of multiple pathways with intermediates by Dinner (1999)
10.1073/pnas.96.12.6716 / Proc Natl Acad Sci USA / Intermediates can accelerate protein folding by Wagner (1999)
10.1021/bi972459k / Biochemistry / Thermodynamic properties of transient intermediates and transition states in the folding of two contrasting protein structures by Parker (1998)
10.1006/jmbi.1998.2588 / J Mol Biol / The Greek key protein apo-pseudoazurin folds through an obligate on-pathway intermediate by Capaldi (1999)
10.1006/jmbi.1996.0647 / J Mol Biol / Titration properties and thermodynamics of the transition state for folding-comparison of 2-state and multistate folding pathways by Tan (1996)
10.1038/10735 / Nat Struct Biol / GroEL accelerates the refolding of hen lysozyme without changing its folding mechanism by Coyle (1999)
10.1126/science.284.5415.822 / Science / Chaperonin function: folding by forced unfolding by Shtilerman (1999)
10.1016/S1359-0278(98)00002-9 / Fold Des / Protein aggregation: folding aggregates, inclusion bodies and amyloid by Fink (1998)
10.1016/S0959-440X(97)80004-8 / Curr Opin Struct Biol / Kinetic role of early intermediates in protein folding by Roder (1997)
10.1073/pnas.94.16.8545 / Proc Natl Acad Sci USA / Ultrafast signals in protein folding and the polypeptide contracted state by Sosnick (1997)
10.1038/2321 / Nat Struct Biol / The burst phase in ribonuclease A folding and solvent dependence of the unfolded state by Qi (1998)
10.1006/jmbi.1998.2548 / J Mol Biol / Rapid folding with and without populated intermediates in the homologous four-helix proteins Im7 and Im9 by Ferguson (1999)
10.1021/ar9700825 / Accounts Chem Res / Kinetics and dynamics of loops, α-helices, β-hairpins, and fast-folding proteins by Eaton (1998)
10.1073/pnas.96.17.9597 / Proc Natl Acad Sci USA / The speed limit for protein folding measured by triplet-triplet energy transfer by Bieri (1999)
10.1073/pnas.93.12.5759 / Proc Natl Acad Sci USA / Direct observation of fast protein folding: the initial collapse of apomyoglobin by Ballew (1996)
10.1073/pnas.92.23.10668 / Proc Natl Acad Sci USA / Submillisecond events in protein-folding by Nolting (1995)
10.1073/pnas.96.12.6587 / Proc Natl Acad Sci USA / Cytochrome b562 folding triggered by electron transfer: approaching the speed limit for formation of a four-helix-bundle protein by Wittung-Stafshede (1999)
10.1038/nsb0598-385 / Nat Struct Biol / Evidence for barrier-limited protein folding kinetics on the microsecond time scale by Shastry (1998)
10.1038/13311 / Nat Struct Biol / Folding dynamics of the B1 domain of protein G explored by ultrarapid mixing by Park (1999)
10.1073/pnas.96.18.10115 / Proc Natl Acad Sci USA / Compactness of the denatured state of a fast-folding protein measured by submillisecond small-angle X-ray scattering by Pollack (1999)
10.1038/9329 / Nat Struct Biol / Chain collapse can occur concomitantly with the rate-limiting step in protein folding by Plaxco (1999)
10.1038/36626 / Nature / Folding dynamics and mechanism of β-hairpin formation by Muñoz (1997)
10.1006/jmbi.1998.2474 / J Mol Biol / Using loop length variants to dissect the folding pathway of a four-helix-bundle protein by Nagi (1999)
10.1021/bi980245c / Biochemistry / Protein folding dynamics: quantitative comparison between theory and experiment by Burton (1998)
10.1006/jmbi.1999.2747 / J Mol Biol / Reinterpretation of GCN4-p1 folding kinetics: partial helix formation precedes dimerization in coiled coil folding by Myers (1999)
10.1002/pro.5560070229 / Protein Sci / The early folding kinetics of apomyoglobin by Pappu (1998)
10.1006/jmbi.1998.2200 / J Mol Biol / The single helix in protein L is largely disrupted at the rate-limiting step in folding by Kim (1998)
10.1038/43937 / Nature / Interpreting the folding kinetics of helical proteins by Zhou (1999)
10.1006/jmbi.1999.2687 / J Mol Biol / Rapid collapse and slow structural reorganisation during the refolding of bovine α-lactalbumin by Forge (1999)
10.1006/jmbi.1999.2741 / J Mol Biol / Independent nucleation and heterogeneous assembly of structure during folding of equine lysozyme by Morozova-Roche (1999)
10.1073/pnas.82.12.4028 / Proc Natl Acad Sci USA / Is there a single pathway for the folding of a polypeptide chain? by Harrison (1985)
10.1006/jmbi.1998.2010 / J Mol Biol / Structural characterization of the transition state for folding of muscle acylphosphatase by Chiti (1998)
10.1006/jmbi.1999.2941 / J Mol Biol / Folding pathway of FKBP12 and characterisation of the transition state by Main (1999)
10.1021/bi9509661 / Biochemistry / Formation of electrostatic interactions on the protein folding pathway by Oliveberg (1996)
10.1021/bi972798d / Biochemistry / Movement of the intermediate and rate determining transition state of barnase on the energy landscape with changing temperature by Dalby (1998)
10.1038/12287 / Nat Struct Biol / Does trifluoroethanol affect folding pathways and can it be used as a probe of structure in transition states? by Main (1999)
{'key': '10.1016/S0959-440X(99)00043-3_BIB57', 'series-title': 'Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding, edn 1', 'author': 'Fersht', 'year': '1998'} / Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding, edn 1 by Fersht (1998)
10.1021/ja981558y / J Am Chem Soc / Combined molecular dynamics and Φ-value analysis of structure-reactivity relationships in the transition state and unfolding pathway of barnase: structural basis of Hammond and anti-Hammond effects by Daggett (1998)
10.1006/jmbi.1996.0173 / J Mol Biol / Structure of the transition state for folding of a protein derived from experiment and simulation by Daggett (1996)
10.1006/jmbi.1999.2942 / J Mol Biol / Mapping the interactions present in the transition state for unfolding/folding of FKBP12 by Fulton (1999)
10.1038/9384 / Nat Struct Biol / The formation of a native-like structure containing eight conserved hydrophobic residues is rate limiting in two-state protein folding of ACBP by Kragelund (1999)
10.1006/jmbi.1997.0932 / J Mol Biol / Following co-operative formation of secondary and tertiary structure in a single protein module by Neira (1997)
10.1006/jmbi.1998.2249 / J Mol Biol / Exploring the folding funnel of a polypeptide chain by biophysical studies on protein fragments by Neira (1999)
10.1006/jmbi.1999.2602 / J Mol Biol / Acquisition of native-like interactions in C-terminal fragments of barnase by Neira (1999)
10.1038/379096a0 / Nature / Conserved residues and the mechanism of protein folding by Shakhnovich (1996)
10.1038/nsb1096-874 / Nat Struct Biol / Different folding transition states may result in the same native structure by Viguera (1996)
10.1021/bi982819j / Biochemistry / Structural changes in the transition state of protein folding: alternative interpretations of curved chevron plots by Otzen (1999)
10.1073/pnas.95.15.8473 / Proc Natl Acad Sci USA / Synergy between simulation and experiment in describing the energy landscape of protein folding by Ladurner (1998)
10.1126/science.282.5389.740 / Science / Pathways to a protein folding intermediate observed in a 1-microsecond simulation in aqueous solution by Duan (1998)
10.1016/S0968-0004(99)01453-X / Trends Biochem Sci / The study of protein mechanics with the atomic force microscope by Fisher (1999)
10.1038/30270 / Nature / The molecular elasticity of the extracellular matrix protein tenascin by Oberhauser (1998)
10.1016/S0006-3495(98)77741-0 / Biophys J / The mechanical stability of immunoglobulin and fibronectin III domains in the muscle protein titin measured by atomic force microscopy by Rief (1998)
10.1006/jmbi.1998.2466 / J Mol Biol / Single molecule force spectroscopy of spectrin repeats: low unfolding forces in helix bundles by Rief (1999)
10.1073/pnas.96.7.3694 / Proc Natl Acad Sci USA / Mechanical and chemical unfolding of a single protein: a comparison by Carrion-Vazquez (1999)
10.1016/S0006-3495(98)77556-3 / Biophys J / Unfolding of titin immunoglobulin domains by steered molecular dynamics simulation by Lu (1998)
10.1006/jmbi.1999.2670 / J Mol Biol / Forced unfolding of fibronectin type 3 modules: an analysis by biased molecular dynamics simulations by Paci (1999)
10.1073/pnas.96.4.1351 / Proc Natl Acad Sci USA / Forced unfolding of the fibronectin type III module reveals a tensile molecular recognition switch by Krammer (1999)
10.1073/pnas.96.11.6166 / Proc Natl Acad Sci USA / Stretching single-domain proteins: phase diagram and kinetics of force-induced unfolding by Klimov (1999)
10.1103/PhysRevE.57.R6281 / Phys Rev E / Detection and identification of a single DNA base molecule using surface-enhanced Raman scattering (SERS) by Kneipp (1998)
10.1038/14901 / Nat Struct Biol / Experiment and theory highlight the role of native state topology in SH3 folding by Riddle (1999)
10.1038/14890 / Nat Struct Biol / Mutational analysis of acylphosphatase suggests the importance of topology and contact order in protein folding by Chiti (1999)
10.1038/47083 / Nature / Mechanical unfolding intermediates in titin molecules by Marszalek (1999)

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 11:50 a.m.)
Deposited	5 years, 7 months ago (Jan. 10, 2020, 2:22 p.m.)
Indexed	1 year, 6 months ago (Feb. 10, 2024, 2:25 p.m.)
Issued	25 years, 6 months ago (Feb. 1, 2000)
Published	25 years, 6 months ago (Feb. 1, 2000)
Published Print	25 years, 6 months ago (Feb. 1, 2000)

Funders 0

None

BibTeX

@article{Brockwell_2000, title={Protein folding mechanisms: new methods and emerging ideas}, volume={10}, ISSN={0959-440X}, url={http://dx.doi.org/10.1016/s0959-440x(99)00043-3}, DOI={10.1016/s0959-440x(99)00043-3}, number={1}, journal={Current Opinion in Structural Biology}, publisher={Elsevier BV}, author={Brockwell, David J and Smith, D Alastair and Radford, Sheena E}, year={2000}, month=feb, pages={16–25} }

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      "first-page": "1621",
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      "article-title": "The Greek key protein apo-pseudoazurin folds through an obligate on-pathway intermediate",
      "volume": "286",
      "author": "Capaldi",
      "year": "1999",
      "journal-title": "J Mol Biol"
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      "article-title": "Titration properties and thermodynamics of the transition state for folding-comparison of 2-state and multistate folding pathways",
      "volume": "264",
      "author": "Tan",
      "year": "1996",
      "journal-title": "J Mol Biol"
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      "first-page": "683",
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      "author": "Coyle",
      "year": "1999",
      "journal-title": "Nat Struct Biol"
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      "first-page": "822",
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      "article-title": "Chaperonin function: folding by forced unfolding",
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      "author": "Shtilerman",
      "year": "1999",
      "journal-title": "Science"
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      "volume": "3",
      "author": "Fink",
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      "volume": "7",
      "author": "Roder",
      "year": "1997",
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      "first-page": "8545",
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      "article-title": "Ultrafast signals in protein folding and the polypeptide contracted state",
      "volume": "94",
      "author": "Sosnick",
      "year": "1997",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
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      "first-page": "882",
      "DOI": "10.1038/2321",
      "article-title": "The burst phase in ribonuclease A folding and solvent dependence of the unfolded state",
      "volume": "5",
      "author": "Qi",
      "year": "1998",
      "journal-title": "Nat Struct Biol"
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      "volume": "286",
      "author": "Ferguson",
      "year": "1999",
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      "volume": "31",
      "author": "Eaton",
      "year": "1998",
      "journal-title": "Accounts Chem Res"
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      "volume": "96",
      "author": "Bieri",
      "year": "1999",
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    },
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      "first-page": "5759",
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      "article-title": "Direct observation of fast protein folding: the initial collapse of apomyoglobin",
      "volume": "93",
      "author": "Ballew",
      "year": "1996",
      "journal-title": "Proc Natl Acad Sci USA"
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      "first-page": "10668",
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      "author": "Nolting",
      "year": "1995",
      "journal-title": "Proc Natl Acad Sci USA"
    },
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      "volume": "96",
      "author": "Wittung-Stafshede",
      "year": "1999",
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      "first-page": "385",
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      "article-title": "Evidence for barrier-limited protein folding kinetics on the microsecond time scale",
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      "author": "Shastry",
      "year": "1998",
      "journal-title": "Nat Struct Biol"
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    {
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      "first-page": "943",
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      "volume": "6",
      "author": "Park",
      "year": "1999",
      "journal-title": "Nat Struct Biol"
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      "volume": "96",
      "author": "Pollack",
      "year": "1999",
      "journal-title": "Proc Natl Acad Sci USA"
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      "first-page": "554",
      "DOI": "10.1038/9329",
      "article-title": "Chain collapse can occur concomitantly with the rate-limiting step in protein folding",
      "volume": "6",
      "author": "Plaxco",
      "year": "1999",
      "journal-title": "Nat Struct Biol"
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    {
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      "first-page": "196",
      "DOI": "10.1038/36626",
      "article-title": "Folding dynamics and mechanism of \u03b2-hairpin formation",
      "volume": "390",
      "author": "Mu\u00f1oz",
      "year": "1997",
      "journal-title": "Nature"
    },
    {
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      "first-page": "257",
      "DOI": "10.1006/jmbi.1998.2474",
      "article-title": "Using loop length variants to dissect the folding pathway of a four-helix-bundle protein",
      "volume": "286",
      "author": "Nagi",
      "year": "1999",
      "journal-title": "J Mol Biol"
    },
    {
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      "doi-asserted-by": "crossref",
      "first-page": "5337",
      "DOI": "10.1021/bi980245c",
      "article-title": "Protein folding dynamics: quantitative comparison between theory and experiment",
      "volume": "37",
      "author": "Burton",
      "year": "1998",
      "journal-title": "Biochemistry"
    },
    {
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      "first-page": "205",
      "DOI": "10.1006/jmbi.1999.2747",
      "article-title": "Reinterpretation of GCN4-p1 folding kinetics: partial helix formation precedes dimerization in coiled coil folding",
      "volume": "289",
      "author": "Myers",
      "year": "1999",
      "journal-title": "J Mol Biol"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "480",
      "DOI": "10.1002/pro.5560070229",
      "article-title": "The early folding kinetics of apomyoglobin",
      "volume": "7",
      "author": "Pappu",
      "year": "1998",
      "journal-title": "Protein Sci"
    },
    {
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      "doi-asserted-by": "crossref",
      "first-page": "807",
      "DOI": "10.1006/jmbi.1998.2200",
      "article-title": "The single helix in protein L is largely disrupted at the rate-limiting step in folding",
      "volume": "284",
      "author": "Kim",
      "year": "1998",
      "journal-title": "J Mol Biol"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "400",
      "DOI": "10.1038/43937",
      "article-title": "Interpreting the folding kinetics of helical proteins",
      "volume": "401",
      "author": "Zhou",
      "year": "1999",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "673",
      "DOI": "10.1006/jmbi.1999.2687",
      "article-title": "Rapid collapse and slow structural reorganisation during the refolding of bovine \u03b1-lactalbumin",
      "volume": "288",
      "author": "Forge",
      "year": "1999",
      "journal-title": "J Mol Biol"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB50",
      "doi-asserted-by": "crossref",
      "first-page": "1055",
      "DOI": "10.1006/jmbi.1999.2741",
      "article-title": "Independent nucleation and heterogeneous assembly of structure during folding of equine lysozyme",
      "volume": "289",
      "author": "Morozova-Roche",
      "year": "1999",
      "journal-title": "J Mol Biol"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB51",
      "doi-asserted-by": "crossref",
      "first-page": "4028",
      "DOI": "10.1073/pnas.82.12.4028",
      "article-title": "Is there a single pathway for the folding of a polypeptide chain?",
      "volume": "82",
      "author": "Harrison",
      "year": "1985",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB52",
      "doi-asserted-by": "crossref",
      "first-page": "893",
      "DOI": "10.1006/jmbi.1998.2010",
      "article-title": "Structural characterization of the transition state for folding of muscle acylphosphatase",
      "volume": "283",
      "author": "Chiti",
      "year": "1998",
      "journal-title": "J Mol Biol"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB53",
      "doi-asserted-by": "crossref",
      "first-page": "429",
      "DOI": "10.1006/jmbi.1999.2941",
      "article-title": "Folding pathway of FKBP12 and characterisation of the transition state",
      "volume": "291",
      "author": "Main",
      "year": "1999",
      "journal-title": "J Mol Biol"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB54",
      "doi-asserted-by": "crossref",
      "first-page": "2726",
      "DOI": "10.1021/bi9509661",
      "article-title": "Formation of electrostatic interactions on the protein folding pathway",
      "volume": "35",
      "author": "Oliveberg",
      "year": "1996",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB55",
      "doi-asserted-by": "crossref",
      "first-page": "4674",
      "DOI": "10.1021/bi972798d",
      "article-title": "Movement of the intermediate and rate determining transition state of barnase on the energy landscape with changing temperature",
      "volume": "37",
      "author": "Dalby",
      "year": "1998",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB56",
      "doi-asserted-by": "crossref",
      "first-page": "831",
      "DOI": "10.1038/12287",
      "article-title": "Does trifluoroethanol affect folding pathways and can it be used as a probe of structure in transition states?",
      "volume": "6",
      "author": "Main",
      "year": "1999",
      "journal-title": "Nat Struct Biol"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB57",
      "series-title": "Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding, edn 1",
      "author": "Fersht",
      "year": "1998"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB58",
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      "first-page": "12740",
      "DOI": "10.1021/ja981558y",
      "article-title": "Combined molecular dynamics and \u03a6-value analysis of structure-reactivity relationships in the transition state and unfolding pathway of barnase: structural basis of Hammond and anti-Hammond effects",
      "volume": "120",
      "author": "Daggett",
      "year": "1998",
      "journal-title": "J Am Chem Soc"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB59",
      "doi-asserted-by": "crossref",
      "first-page": "430",
      "DOI": "10.1006/jmbi.1996.0173",
      "article-title": "Structure of the transition state for folding of a protein derived from experiment and simulation",
      "volume": "257",
      "author": "Daggett",
      "year": "1996",
      "journal-title": "J Mol Biol"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB60",
      "doi-asserted-by": "crossref",
      "first-page": "445",
      "DOI": "10.1006/jmbi.1999.2942",
      "article-title": "Mapping the interactions present in the transition state for unfolding/folding of FKBP12",
      "volume": "291",
      "author": "Fulton",
      "year": "1999",
      "journal-title": "J Mol Biol"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB61",
      "doi-asserted-by": "crossref",
      "first-page": "594",
      "DOI": "10.1038/9384",
      "article-title": "The formation of a native-like structure containing eight conserved hydrophobic residues is rate limiting in two-state protein folding of ACBP",
      "volume": "6",
      "author": "Kragelund",
      "year": "1999",
      "journal-title": "Nat Struct Biol"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB62",
      "doi-asserted-by": "crossref",
      "first-page": "185",
      "DOI": "10.1006/jmbi.1997.0932",
      "article-title": "Following co-operative formation of secondary and tertiary structure in a single protein module",
      "volume": "268",
      "author": "Neira",
      "year": "1997",
      "journal-title": "J Mol Biol"
    },
    {
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      "doi-asserted-by": "crossref",
      "first-page": "1309",
      "DOI": "10.1006/jmbi.1998.2249",
      "article-title": "Exploring the folding funnel of a polypeptide chain by biophysical studies on protein fragments",
      "volume": "285",
      "author": "Neira",
      "year": "1999",
      "journal-title": "J Mol Biol"
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    {
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      "first-page": "421",
      "DOI": "10.1006/jmbi.1999.2602",
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      "author": "Neira",
      "year": "1999",
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    },
    {
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      "first-page": "96",
      "DOI": "10.1038/379096a0",
      "article-title": "Conserved residues and the mechanism of protein folding",
      "volume": "379",
      "author": "Shakhnovich",
      "year": "1996",
      "journal-title": "Nature"
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    {
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      "first-page": "874",
      "DOI": "10.1038/nsb1096-874",
      "article-title": "Different folding transition states may result in the same native structure",
      "volume": "3",
      "author": "Viguera",
      "year": "1996",
      "journal-title": "Nat Struct Biol"
    },
    {
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      "doi-asserted-by": "crossref",
      "first-page": "6499",
      "DOI": "10.1021/bi982819j",
      "article-title": "Structural changes in the transition state of protein folding: alternative interpretations of curved chevron plots",
      "volume": "38",
      "author": "Otzen",
      "year": "1999",
      "journal-title": "Biochemistry"
    },
    {
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      "first-page": "8473",
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      "article-title": "Synergy between simulation and experiment in describing the energy landscape of protein folding",
      "volume": "95",
      "author": "Ladurner",
      "year": "1998",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
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      "doi-asserted-by": "crossref",
      "first-page": "740",
      "DOI": "10.1126/science.282.5389.740",
      "article-title": "Pathways to a protein folding intermediate observed in a 1-microsecond simulation in aqueous solution",
      "volume": "282",
      "author": "Duan",
      "year": "1998",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB70",
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      "first-page": "379",
      "DOI": "10.1016/S0968-0004(99)01453-X",
      "article-title": "The study of protein mechanics with the atomic force microscope",
      "volume": "24",
      "author": "Fisher",
      "year": "1999",
      "journal-title": "Trends Biochem Sci"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB71",
      "doi-asserted-by": "crossref",
      "first-page": "181",
      "DOI": "10.1038/30270",
      "article-title": "The molecular elasticity of the extracellular matrix protein tenascin",
      "volume": "393",
      "author": "Oberhauser",
      "year": "1998",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB72",
      "doi-asserted-by": "crossref",
      "first-page": "3008",
      "DOI": "10.1016/S0006-3495(98)77741-0",
      "article-title": "The mechanical stability of immunoglobulin and fibronectin III domains in the muscle protein titin measured by atomic force microscopy",
      "volume": "75",
      "author": "Rief",
      "year": "1998",
      "journal-title": "Biophys J"
    },
    {
      "key": "10.1016/S0959-440X(99)00043-3_BIB73",
      "doi-asserted-by": "crossref",
      "first-page": "553",
      "DOI": "10.1006/jmbi.1998.2466",
      "article-title": "Single molecule force spectroscopy of spectrin repeats: low unfolding forces in helix bundles",
      "volume": "286",
      "author": "Rief",
      "year": "1999",
      "journal-title": "J Mol Biol"
    },
    {
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      "first-page": "3694",
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      "volume": "96",
      "author": "Carrion-Vazquez",
      "year": "1999",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
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      "first-page": "662",
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      "article-title": "Unfolding of titin immunoglobulin domains by steered molecular dynamics simulation",
      "volume": "75",
      "author": "Lu",
      "year": "1998",
      "journal-title": "Biophys J"
    },
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      "doi-asserted-by": "crossref",
      "first-page": "441",
      "DOI": "10.1006/jmbi.1999.2670",
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      "volume": "288",
      "author": "Paci",
      "year": "1999",
      "journal-title": "J Mol Biol"
    },
    {
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      "first-page": "1351",
      "DOI": "10.1073/pnas.96.4.1351",
      "article-title": "Forced unfolding of the fibronectin type III module reveals a tensile molecular recognition switch",
      "volume": "96",
      "author": "Krammer",
      "year": "1999",
      "journal-title": "Proc Natl Acad Sci USA"
    },
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