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Current Opinion in Structural Biology (78)
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Uphoff, K. W., Bell, S. D., & Ellington, A. D. (1996). In vitro selection of aptamers: the dearth of pure reason. Current Opinion in Structural Biology, 6(3), 281–288.

Authors 3
  1. Kyle W Uphoff (first)
  2. Sabine D Bell (additional)
  3. Andrew D Ellington (additional)
References 51 Referenced 59
  1. 10.1016/0022-2836(74)90047-3 / J Mol Biol / Evolution of in vitro sequence and phenotype of a mutant RNA resistant to ethidium bromide by Kramer (1974)
  2. 10.1098/rspb.1979.0077 / Proc R Soc Lond B Biol Sci / Selection in vitro by Orgel (1979)
  3. {'key': '10.1016/S0959-440X(96)80045-5_BIB3', 'first-page': '87', 'article-title': 'Structure and activity of ribozymes', 'author': 'Szostak', 'year': '1988'} / Structure and activity of ribozymes by Szostak (1988)
  4. 10.1146/annurev.bi.64.070195.003555 / Annu Rev Biochem / Diversity of oligonucleotide functions by Gold (1995)
  5. 10.1074/jbc.270.23.13581 / J Biol Chem / Oligonucleotides as research, diagnostic, and therapeutic agents by Gold (1995)
  6. {'key': '10.1016/S0959-440X(96)80045-5_BIB6', 'first-page': '185', 'article-title': 'Aptamers as potential nucleic acid pharmaceuticals', 'volume': '1', 'author': 'Ellington', 'year': '1995'} / Aptamers as potential nucleic acid pharmaceuticals by Ellington (1995)
  7. 10.1016/0968-0004(94)90033-7 / Trends Biochem Sci / Exploring molecular diversity with combinatorial shape libraries by Kenan (1994)
  8. 10.1007/BF00996358 / Mol Biol Rep / All you wanted to know about SELEX by Klug (1994)
  9. 10.1007/BF01715810 / Mol Div / In vitro selection methodologies to probe RNA function and structure by Conrad (1995)
  10. 10.1016/S0960-9822(95)00205-3 / Curr Biol / Re-creating the RNA world by Hirao (1995)
  11. 10.1016/S0960-9822(00)00093-2 / Curr Biol / Aptamers achieve the desired recognition by Ellington (1994)
  12. {'key': '10.1016/S0959-440X(96)80045-5_BIB12', 'first-page': '538', 'article-title': 'Selection of an RNA domain that binds Zn2+', 'volume': '1', 'author': 'Ciesiolka', 'year': '1995', 'journal-title': 'RNA'} / RNA / Selection of an RNA domain that binds Zn2+ by Ciesiolka (1995)
  13. 10.1016/1074-5521(95)90047-0 / Chem Biol / Specific binding of aminoglycoside antibiotics to RNA by Wang (1995)
  14. 10.1016/1074-5521(95)90048-9 / Chem Biol / In vitro selection of RNA lectins: using combinatorial chemistry to interpret ribozyme evolution by Lato (1995)
  15. 10.1016/1074-5521(95)90188-4 / Chem Biol / A novel RNA motif for neomycin recognition by Wallis (1995)
  16. 10.1093/nar/23.17.3426 / Nucleic Acids Res / On the role of rRNA tertiary structure in recognition of ribosomal protein L11 and thiostrepton by Lu (1995)
  17. 10.1021/ja00084a010 / J Am Chem Soc / Molecular recognition of amino acids by RNA-aptamers: an l-citrulline binding RNA motif and its evolution into an l-arginine binder by Famulok (1994)
  18. 10.1093/nar/23.23.4769 / Nucleic Acid Res / Structural probing and damage selection of citrulline- and arginine-specific RNA aptamers identify base positions required for binding by Burgstaller (1995)
  19. 10.1021/bi00002a033 / Biochemistry / A DNA aptamer that binds adenosine and ATP by Huizenga (1995)
  20. 10.1021/ja00109a008 / J Am Chem Soc / RNA aptamers that bind flavin and nicotinamide redox cofactors by Lauhon (1995)
  21. 10.1074/jbc.270.44.26292 / J Biol Chem / DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins by Swanson (1995)
  22. 10.1021/bi00045a018 / Biochemistry / Template recognition by an RNA-dependent RNA polymerase: identification and characterization of two RNA binding sites on Qβ replicase by Brown (1995)
  23. 10.1021/bi00045a019 / Biochemistry / Selection and characterization of RNAs replicated by Qβ replicase by Brown (1995)
  24. 10.1093/nar/23.19.3909 / Nucleic Acids Res / Distinct requirements for primary sequence in the 5′- and 3′-part of a bulge in the hepatitis B virus RNA encapsidation signal revealed by a combined in vivo selection/in vitro amplification system by Rieger (1995)
  25. 10.1128/JVI.69.12.7559-7569.1995 / J Virol / High-resolution mapping of the human T-cell leukemia virus type I Rex-binding element by in vitro selection by Baskerville (1995)
  26. 10.1038/nsb0594-293 / Nat Struct Biol / A three-dimensional model of the Rev-binding element of HIV-1 derived from analyses of aptamers by Leclerc (1994)
  27. 10.1016/S0022-2836(05)80030-0 / J Mol Biol / Characterization of an in vitro-selected RNA ligand to the HIV-1 Rev protein by Jensen (1994)
  28. 10.1021/bi00008a019 / Biochemistry / Defining a smaller RNA substrate for elongation factor Tu by Nazrenko (1995)
  29. 10.1128/jb.177.17.4872-4880.1995 / J Bacteriol / A consensus sequence for binding of Lrp to DNA by Cui (1995)
  30. 10.1021/bi00011a019 / Biochemistry / High-affinity RNA ligands to Escherichia coli ribosomes and ribosomal protein S1: comparison of natural and unnatural binding sites by Ringquist (1995)
  31. 10.1128/JVI.69.12.8027-8034.1995 / J Virol / In vitro selection of RNA ligands for the ribosomal L22 protein associated with Epstein-Barr Virus expressed RNA by using randomized and cDNA-derived RNA libraries by Dobbelstein (1995)
  32. 10.1002/j.1460-2075.1995.tb07360.x / EMBO J / The human splicing factors ASF/SF2 and SC35 possess distinct, functionally significant RNA binding specificities by Tacke (1995)
  33. 10.1002/j.1460-2075.1995.tb00070.x / EMBO J / The Drosophila SR protein RBP1 contributes to the regulation of doublesex alternative splicing by recognizing RBP1 RNA target sequences by Heinrichs (1995)
  34. 10.1126/science.7761834 / Science / Distinct binding specificities and functions of higher eucaryotic polypyrimidine tract-binding proteins by Singh (1995)
  35. 10.1021/bi00029a037 / Biochemistry / High-affinity ssDNA inhibitors of the reverse transcriptase of type 1 human immunodeficiency virus by Schneider (1995)
  36. 10.1006/jmbi.1994.0122 / J Mol Biol / Comprehensive chemical modification interference and nucleotide substitution analysis of an RNA pseudoknot inhibitor to HIV-1 reverse transcriptase by Green (1995)
  37. 10.1006/viro.1995.1264 / Virology / Isolation of a high-affinity RNA ligands to HIV-1 integrase from a random pool by Allen (1995)
  38. 10.1128/JVI.70.1.179-187.1996 / J Virol / RNA aptamers selected to bind human immunodeficiency virus type 1 Rev in vitro are Rev responsive in vivo by Symensma (1996)
  39. {'key': '10.1016/S0959-440X(96)80045-5_BIB39', 'first-page': '317', 'article-title': 'Dissecting protein:protein interactions between transcription factors with an RNA aptamer', 'volume': '1', 'author': 'Tian', 'year': '1995', 'journal-title': 'RNA'} / RNA / Dissecting protein:protein interactions between transcription factors with an RNA aptamer by Tian (1995)
  40. 10.1073/pnas.92.25.11509 / Proc Natl Acad Sci USA / Isolation of virus-neutralizing RNAs from a large pool of random sequences by Pan (1995)
  41. 10.1016/S0021-9258(18)31598-9 / J Biol Chem / Isozyme-specific inhibition of protein kinase C by RNA aptamers by Conrad (1994)
  42. 10.1093/nar/23.16.3198 / Nucleic Acids Res / RNA ligands to human nerve growth factor by Binkley (1995)
  43. 10.1021/bi00016a041 / Biochemistry / In vitro selection of RNA ligands to substance P by Nieuwlandt (1995)
  44. 10.1021/bi00036a009 / Biochemistry / Potent 2'-amino-2'-deoxypyrimidine RNA inhibitors of basic fibroblast growth factor by Jellinek (1995)
  45. 10.1016/1074-5521(95)90032-2 / Chem Biol / Nuclease-resistant nucleic acid ligands to vascular permeability factor/vascular endothelial growth factor by Green (1995)
  46. 10.1016/1074-5521(95)90102-7 / Chem Biol / In vitro selection of RNA-based irreversible inhibitors of human neutrophil elastase by Smith (1995)
  47. 10.1073/pnas.92.24.11044 / Proc Natl Acad Sci USA / Peptide conjugation to an in vitro-selected DNA ligand improves enzyme inhibition by Lin (1995)
  48. 10.1073/pnas.92.26.12220 / Proc Natl Acad Sci USA / Using in vitro selection to direct the covalent attachment of human immunodeficiency virus type 1 Rev protein to high-affinity RNA ligands by Jensen (1995)
  49. 10.1016/1074-5521(95)90023-3 / Chem Biol / Let's get specific: the relationship between specificity and affinity by Eaton (1995)
  50. 10.1021/bi00013a041 / Biochemistry / Structural and functional characterization of potent antithrombotic oligonucleotides possessing both quadruplex and duplex motifs by Macaya (1995)
  51. 10.1074/jbc.270.33.19370 / J Biol Chem / Selection of a suppressor mutation that restores affinity of an oligonucleotide inhibitor for thrombin using in vitro genetics by Tsiang (1995)
Dates
Type When
Created 23 years, 1 month ago (July 25, 2002, 6:33 a.m.)
Deposited 4 years, 3 months ago (May 4, 2021, 8:38 a.m.)
Indexed 1 month, 4 weeks ago (July 2, 2025, 11:57 a.m.)
Issued 29 years, 2 months ago (June 1, 1996)
Published 29 years, 2 months ago (June 1, 1996)
Published Print 29 years, 2 months ago (June 1, 1996)
Funders 0

None

@article{Uphoff_1996, title={In vitro selection of aptamers: the dearth of pure reason}, volume={6}, ISSN={0959-440X}, url={http://dx.doi.org/10.1016/s0959-440x(96)80045-5}, DOI={10.1016/s0959-440x(96)80045-5}, number={3}, journal={Current Opinion in Structural Biology}, publisher={Elsevier BV}, author={Uphoff, Kyle W and Bell, Sabine D and Ellington, Andrew D}, year={1996}, month=jun, pages={281–288} }