DOI: 10.1016/s0959-440x(00)00184-6. Atomic structures at last: the ribosome in 2000

Atomic structures at last: the ribosome in 2000

10.1016/s0959-440x(00)00184-6

Crossref journal-article

Elsevier BV

Current Opinion in Structural Biology (78)

Bibliography

Ramakrishnan, V., & Moore, P. B. (2001). Atomic structures at last: the ribosome in 2000. Current Opinion in Structural Biology, 11(2), 144â154.

Authors 2

V Ramakrishnan (first)
P.B Moore (additional)

References 60 Referenced 115

Garrett R.A., Douthwaite S.R., Liljas A., Matheson A.T., Moore P.B., Noller H.F. (Eds): The Ribosome. Structure, Function, Antibiotics and Cellular Interactions. Washington, DC: ASM Press; 2000. Until the successor volume to this one is produced by the ribosome community, this book will be the best single reference for those interested in understanding the state of the ribosome field. (10.1128/9781555818142)
{'key': '10.1016/S0959-440X(00)00184-6_BIB2', 'first-page': '428', 'article-title': 'Crystallization of the large ribosomal subunits from Bacillus stearothermophilus', 'volume': '1', 'author': 'Yonath', 'year': '1980', 'journal-title': 'Biochem Int'} / Biochem Int / Crystallization of the large ribosomal subunits from Bacillus stearothermophilus by Yonath (1980)
10.1016/0014-5793(85)80655-4 / FEBS Lett / Characterization and crystallization of ribosomal particles from Halobacterium marismortui by Shevack (1985)
10.1016/0022-2836(91)90730-T / J Mol Biol / Characterization and preliminary attempts for derivatization of crystals of large ribosomal subunits from Haloarcula marismortui diffracting to 3 Å resolution by von Böhlen (1991)
10.1016/0014-5793(87)80838-4 / FEBS Lett / Crystallization of 70 S ribosomes and 30 S ribosomal subunits from Thermus thermophilus by Trakhanov (1987)
{'key': '10.1016/S0959-440X(00)00184-6_BIB6', 'first-page': '953', 'article-title': 'Three-dimensional crystals of ribosomes and their subunits from eu- and archaebacteria', 'volume': '15', 'author': 'Glotz', 'year': '1987', 'journal-title': 'Biochem Int'} / Biochem Int / Three-dimensional crystals of ribosomes and their subunits from eu- and archaebacteria by Glotz (1987)
10.1107/S010876739800991X / Acta Crystallogr / Crystallographic studies on the ribosome, a large macromolecular assembly exhibiting severe nonisomorphism, extreme beam sensitivity and no internal symmetry by Yonath (1998)
10.1038/23631 / Nature / Structure of a bacterial 30S ribosomal subunit at 5.5 Å resolution by Clemons (1999)
10.1126/science.285.5436.2095 / Science / X-ray crystal structures of 70S ribosome functional complexes by Cate (1999)
{'key': '10.1016/S0959-440X(00)00184-6_BIB10', 'first-page': '1641', 'article-title': 'Cool data: quantity AND quality', 'volume': 'D55', 'author': 'Garman', 'year': '1999', 'journal-title': 'Acta Crystallogr'} / Acta Crystallogr / Cool data: quantity AND quality by Garman (1999)
10.1107/S0108768188013710 / Acta Crystallogr / Cryocrystallography of ribosomal particles by Hope (1989)
10.1107/S0567739477001168 / Acta Crystallogr / Applications of synchrotron radiation to protein crystallography. II. Anomalous scattering, absolute intensity and polarization by Phillips (1977)
10.1016/S0092-8674(00)81455-5 / Cell / A 9 Å resolution X-ray crystallographic map of the large ribosomal subunit by Ban (1998)
10.1016/S0022-2836(75)80032-5 / J Mol Biol / Structure of tomato bushy stunt virus. II. Comparison of results obtained by electron microscopy and X-ray diffraction by Jack (1975)
10.1016/0022-2836(87)90248-8 / J Mol Biol / Multiple heavy-atom reagents for macromolecular X-ray structure determination. Application to the nucleosome core particle by O'Halloran (1987)
10.1038/337229a0 / Nature / Crystal structure of the active-site of ribulose-bisphosphate carboxylase by Andersson (1989)
10.1126/science.1721241 / Science / Structure of the calcium-dependent lectin domain from a rat mannose-binding protein determined by MAD phasing by Weis (1991)
10.1126/science.273.5282.1678 / Science / Crystal structure of a group I ribozyme domain: principles of RNA packing by Cate (1996)
10.1038/23641 / Nature / Placement of protein and RNA structures into a 5 Å-resolution map of the 50S ribosomal subunit by Ban (1999)
10.1073/pnas.96.25.14252 / Proc Natl Acad Sci USA / The small ribosomal subunit from Thermus thermophilus at 4.5 Å resolution: pattern fittings and the identification of a functional site by Tocilj (1999)
10.1126/science.289.5481.905 / Science / The complete atomic structure of the large ribosomal subunit at 2.4 Å resolution by Ban (2000)
10.1016/S0092-8674(00)00084-2 / Cell / Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution by Schluenzen (2000)
10.1038/35030006 / Nature / Structure of the 30S ribosomal subunit by Wimberly (2000)
10.1016/S0969-2126(99)80120-8 / Structure Fold Des / Elucidating the medium-resolution structure of ribosomal particles: an interplay between electron cryo-microscopy and X-ray crystallography by Harms (1999)
10.1126/science.1604315 / Science / Unusual resistance of peptidyl transferase to protein extraction procedures by Noller (1992)
10.1021/bi00002a001 / Biochemistry / An inhibitor of ribosomal peptidyl transferase using transition-state analogy by Welch (1995)
10.1126/science.289.5481.920 / Science / The structural basis of ribosome activity in peptide bond synthesis by Nissen (2000)
10.1126/science.289.5481.947 / Science / A single adenosine with a neutral pKa in the ribosomal peptidyl transferase center by Muth (2000)
10.1093/nar/26.4.887 / Nucleic Acids Res / The path of the growing peptide chain through the 23S rRNA in the 50S ribosomal subunit; a comparative cross-linking study with three different peptide families by Choi (1998)
10.1038/35030019 / Nature / Functional insights from the structure of the 30S ribosomal subunit and its interaction with antibiotics by Carter (2000)
10.1126/science.274.5291.1367 / Science / Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic by Fourmy (1996)
10.1016/0022-2836(90)90016-F / J Mol Biol / Binding of tRNA to the ribosomal A and P sites protects two distinct sets of nucleotides in 16 S rRNA by Moazed (1990)
10.1126/science.285.5434.1722 / Science / Recognition of the codon-anticodon helix by ribosomal RNA by Yoshizawa (1999)
10.1016/S0959-440X(99)80031-1 / Curr Opin Struct Biol / Structural studies of the translational apparatus by Agrawal (1999)
10.1016/S0959-440X(00)00077-4 / Curr Opin Struct Biol / Unveiling ribosomal structures: the final phases by van Heel (2000)
10.1016/S0969-2126(00)88348-3 / Structure Fold Des / The Escherichia coli large ribosomal subunit at 7.5 Å resolution by Matadeen (1999)
10.1006/jmbi.2000.3635 / J Mol Biol / The 3D arrangement of the 23 S and 5 S rRNA in the Escherichia coli 50 S ribosomal subunit based on a cryo-electron microscopic reconstruction at 7.5 Å resolution by Mueller (2000)
10.1016/S0092-8674(00)80690-X / Cell / Solution structure of the E. coli 70S ribosome at 11.5 Å resolution by Gabashvili (2000)
10.1016/S0969-2126(00)88347-1 / Structure Fold Des / Direct three-dimensional localization and positive identification of RNA helices within the ribosome by means of genetic tagging and cryo-electron microscopy by Spahn (1999)
10.1016/S0969-2126(00)00185-4 / Structure Fold Des / A method for differentiating proteins from nucleic acids in intermediate-resolution density maps: cryo-electron microscopy defines the quaternary structure of the Escherichia coli 70S ribosome by Spahn (2000)
10.1006/jmbi.1999.2538 / J Mol Biol / Structure and structural variations of the Escherichia coli 30S ribosomal subunit as revealed by three-dimensional cryo-electron microscopy by Gabashvili (1999)
10.1126/science.277.5330.1262 / Science / A conformational switch in Escherichia coli 16S ribosomal RNA during decoding of messenger RNA by Lodmell (1997)
10.1093/emboj/18.22.6501 / EMBO J / Major rearrangements in the 70S ribosomal 3D structure caused by a conformational switch in 16S ribosomal RNA by Gabashvili (1999)
10.1038/376441a0 / Nature / A model of protein synthesis based on cryo-electron microscopy of the E. coli ribosome by Frank (1995)
10.1006/jmbi.1996.0497 / J Mol Biol / Three-dimensional reconstruction of the Escherichia coli 30S ribosomal subunit in ice by Lata (1996)
10.1038/35018597 / Nature / A ratchet-like inter-subunit reorganization of the ribosome during translocation by Frank (2000)
10.1083/jcb.150.3.447 / J Cell Biol / Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle by Agrawal (2000)
10.1038/342142a0 / Nature / Intermediate states in the movement of transfer RNA in the ribosome by Moazed (1989)
10.1016/S0092-8674(00)81854-1 / Cell / Arrangement of tRNAs in pre- and posttranslocational ribosomes revealed by electron cryomicroscopy by Stark (1997)
10.1515/BC.2000.050 / Biol Chem / GTPases mechanisms and functions of translation factors on the ribosome by Rodnina (2000)
10.1073/pnas.95.11.6134 / Proc Natl Acad Sci USA / Visualization of elongation factor G on the Escherichia coli 70S ribosome: the mechanism of translocation by Agrawal (1998)
10.1016/S0092-8674(00)80666-2 / Cell / Large-scale movement of elongation factor G and extensive conformational change of the ribosome during translocation by Stark (2000)
10.1038/10695 / Nat Struct Biol / EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome by Agrawal (1999)
10.1016/S0006-3495(00)76416-2 / Biophys J / Domain motions of EF-G bound to the 70S ribosome: insights from a hand-shaking between multi-resolution structures by Wriggers (2000)
10.1093/emboj/19.11.2710 / EMBO J / Three-dimensional cryo-electron microscopy localization of EF2 in the Saccharomyces cerevisiae 80S ribosome at 17.5 Å resolution by Gomez-Lorenzo (2000)
10.1073/pnas.96.8.4301 / Proc Natl Acad Sci USA / Location of translational initiation factor IF3 on the small ribosomal subunit by McCutcheon (1999)
10.1107/S0021889891007240 / J Appl Crystallogr / Ribbons 2.0 by Carson (1991)
{'key': '10.1016/S0959-440X(00)00184-6_BIB58', 'series-title': 'Ribsomal RNA. Structure, Evolution, Processing, and Function in Protein Biosynthesis', 'first-page': '111', 'article-title': 'Comparative sequence analysis and the structure of 16S and 23S rRNA', 'author': 'Gutell', 'year': '1996'} / Ribsomal RNA. Structure, Evolution, Processing, and Function in Protein Biosynthesis / Comparative sequence analysis and the structure of 16S and 23S rRNA by Gutell (1996)
10.1016/S0092-8674(00)00216-6 / Cell / The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit by Brodersen (2000)
10.1126/science.1057766 / Science / Crystal structure of an initiation factor bound to the 30S ribosomal subunit by Carter (2001)

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 4:54 p.m.)
Deposited	5 years, 7 months ago (Jan. 17, 2020, 12:43 a.m.)
Indexed	2 weeks, 2 days ago (Aug. 12, 2025, 5:32 p.m.)
Issued	24 years, 4 months ago (April 1, 2001)
Published	24 years, 4 months ago (April 1, 2001)
Published Print	24 years, 4 months ago (April 1, 2001)

Funders 0

None

BibTeX

@article{Ramakrishnan_2001, title={Atomic structures at last: the ribosome in 2000}, volume={11}, ISSN={0959-440X}, url={http://dx.doi.org/10.1016/s0959-440x(00)00184-6}, DOI={10.1016/s0959-440x(00)00184-6}, number={2}, journal={Current Opinion in Structural Biology}, publisher={Elsevier BV}, author={Ramakrishnan, V and Moore, P.B}, year={2001}, month=apr, pages={144–154} }

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      "author": "Muth",
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      "volume": "26",
      "author": "Choi",
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      "author": "Fourmy",
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      "author": "Yoshizawa",
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      "volume": "298",
      "author": "Mueller",
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      "author": "Spahn",
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      "author": "Frank",
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      "author": "Lata",
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      "author": "Stark",
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      "author": "Rodnina",
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      "author": "Agrawal",
      "year": "1998",
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      "volume": "79",
      "author": "Wriggers",
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