DOI: 10.1016/s0959-4388(99)00013-6. Polyglutamine diseases: protein cleavage and aggregation

Polyglutamine diseases: protein cleavage and aggregation

10.1016/s0959-4388(99)00013-6

Crossref journal-article

Elsevier BV

Current Opinion in Neurobiology (78)

Bibliography

Zoghbi, H. Y., & Orr, H. T. (1999). Polyglutamine diseases: protein cleavage and aggregation. Current Opinion in Neurobiology, 9(5), 566â570.

Authors 2

Huda Y Zoghbi (first)
Harry T Orr (additional)

References 36 Referenced 82

10.1016/S0896-6273(00)80405-5 / Neuron / Intranuclear neuronal inclusions: a common pathogenic mechanism for glutamine-repeat neurodegeneration disease? by Ross (1997)
10.1038/352077a0 / Nature / Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy by La Spada (1991)
10.1016/0092-8674(93)90718-6 / Cell / Human genetic diseases due to codon reiteration: relationship to an evoluntionary mechanism by Green (1993)
10.1073/pnas.91.12.5355 / Proc Natl Acad Sci USA / Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases by Perutz (1994)
10.1038/ng0696-196 / Nat Genet / Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo by Ikeda (1996)
10.1016/S0092-8674(00)81369-0 / Cell / Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice by Mangiarini (1996)
10.1016/S0092-8674(00)80464-X / Cell / Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse by Ordway (1997)
10.1016/S0092-8674(00)80513-9 / Cell / Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation by Davies (1997)
10.1016/S0092-8674(00)80514-0 / Cell / Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo by Scherzinger (1997)
10.1126/science.277.5334.1990 / Science / Aggregation of Huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain by DiFiglia (1997)
10.1016/S0896-6273(00)80943-5 / Neuron / Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3 by Paulson (1997)
10.1038/40153 / Nature / Ataxin-1 with extra glutamines induces alterations in nuclear matrix-associated structures by Skinner (1997)
10.1093/hmg/7.5.913 / Hum Mol Genet / Spinocerebellar ataxia type 7 (SCA7): a neurodegenerative disorder with neuronal intranuclear inclusions by Holmberg (1998)
10.1002/ana.410440216 / Ann Neurol / Nuclear inclusions of the androgen receptor in spinal and bulbar muscular atrophy by Li (1998)
10.1006/nbdi.1998.0168 / Neurobiol Dis / Intranuclear neuronal inclusions in Huntington’s disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length by Becher (1998)
10.1016/S0140-6736(97)08360-8 / Lancet / Are neuronal intranuclear inclusions the common neuropathology of triplet-repeat disorders with polyglutamine-repeat expansions? by Davies (1998)
10.1016/S0968-0004(98)01350-4 / Trends Biochem Sci / Glutamine repeats and neurodegenerative diseases: molecular aspects by Perutz (1999)
10.1038/502 / Nat Genet / Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1 by Cummings (1998)
10.1093/hmg/8.4.673 / Hum Mol Genet / Evidence for HDJ-2/HSDJ proteasome involvement in polyglutamine disease: localization to nuclear inclusions in SCA3/MJD and suppression of polyglutamine aggregation in vitro by Chai (1999)
10.1093/hmg/8.5.731 / Hum Mol Genet / Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ–2 chaperone by Stenoien (1999)
10.1038/ng0298-150 / Nat Genet / Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates by Martindale (1998)
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10.1016/0092-8674(95)90422-0 / Cell / Protease activation during apoptosis: death by a thousand cuts? by Martin (1995)
10.1038/ng0896-442 / Nat Genet / Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract by Goldberg (1996)
10.1074/jbc.273.15.9158 / J Biol Chem / Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract by Wellington (1998)
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10.1038/20446 / Nature / Inhibition of caspase-1 slows disease progression in a mouse model of Huntington’s disease by Ona (1999)
10.1016/S0092-8674(00)81782-1 / Cell / Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions by Saudou (1998)
10.1002/1531-8249(199902)45:2<232::AID-ANA14>3.0.CO;2-7 / Ann Neurol / Expression of ataxin-2 in brains from normal individuals and patients with Alzheimer’s disease and spinocerebellar ataxia 2 by Huynh (1999)
10.1016/S0092-8674(00)81781-X / Cell / Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice by Klement (1998)
10.1038/2510 / Nat Genet / Behavioral abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA by Reddy (1998)
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10.1101/gad.12.10.1391 / Genes Dev / SAPKs and transcription factors do the nucleocytoplasmic tango [comment] by Wilkinson (1998)

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 9:27 a.m.)
Deposited	5 years, 7 months ago (Jan. 13, 2020, 5:11 a.m.)
Indexed	3 months ago (June 2, 2025, 5:27 a.m.)
Issued	25 years, 11 months ago (Oct. 1, 1999)
Published	25 years, 11 months ago (Oct. 1, 1999)
Published Print	25 years, 11 months ago (Oct. 1, 1999)

Funders 0

None

BibTeX

@article{Zoghbi_1999, title={Polyglutamine diseases: protein cleavage and aggregation}, volume={9}, ISSN={0959-4388}, url={http://dx.doi.org/10.1016/s0959-4388(99)00013-6}, DOI={10.1016/s0959-4388(99)00013-6}, number={5}, journal={Current Opinion in Neurobiology}, publisher={Elsevier BV}, author={Zoghbi, Huda Y and Orr, Harry T}, year={1999}, month=oct, pages={566–570} }

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