DOI: 10.1016/s0959-4388(02)00287-8. Revisiting cell fate specification in the inner ear

Revisiting cell fate specification in the inner ear

10.1016/s0959-4388(02)00287-8

Crossref journal-article

Elsevier BV

Current Opinion in Neurobiology (78)

Bibliography

Fekete, D. M., & Wu, D. K. (2002). Revisiting cell fate specification in the inner ear. Current Opinion in Neurobiology, 12(1), 35â42.

Authors 2

Donna M Fekete (first)
Doris K Wu (additional)

References 65 Referenced 239

10.1016/S0959-4388(96)80061-4 / Curr Opin Neurobiol / Cell fate specification in the inner ear by Fekete (1996)
10.1242/dev.127.16.3489 / Development / Competence, specification and commitment in otic placode induction by Groves (2000)
10.1126/science.290.5498.1965 / Science / Identification of synergistic signals initiating inner ear development by Ladher (2000)
10.1242/dev.127.10.2011 / Development / Induction of inner ear fate by FGF3 by Vendrell (2000)
10.1016/S0168-9525(99)01774-6 / Trends Genet / Compartment boundaries: at the edge of development by Dahmann (1999)
10.1073/pnas.97.22.11700 / Proc Natl Acad Sci USA / Molecular genetics of pattern formation in the inner ear: do compartment boundaries play a role? by Brigande (2000)
10.1006/dbio.1997.8716 / Dev Biol / The expression domain of two related homeobox genes defines a compartment in the chicken inner ear that may be involved in semicircular canal formation by Kiernan (1997)
10.1006/dbio.1998.9023 / Dev Biol / Regionalized organizing activity of the neural tube revealed by the regulation of lmx1 in the otic vesicle by Giraldez (1998)
10.1242/dev.125.4.645 / Development / Two regulatory genes, cNkx5-1 and cPax2, show different responses to local signals during otic placode and vesicle formation in the chick embryo by Herbrand (1998)
10.1023/A:1007057719025 / J Neurocytol / Expression of Pax2 and patterning of the chick inner ear by Hutson (1999)
10.1006/dbio.1996.0081 / Dev Biol / The role of FGF-3 in early inner ear development: an analysis in normal and kreisler mutant mice by McKay (1996)
10.1242/dev.125.1.11 / Development / Axial specification for sensory organs versus non-sensory structures of the chicken inner ear by Wu (1998)
10.1006/dbio.2000.9914 / Dev Biol / A fate map of chick otic cup closure reveals lineage boundaries in the dorsal otocyst by Brigande (2000)
10.1007/s101620010017 / JARO / Neurogenin 1 null mutant ears develop fewer, morphologically normal hair cells in smaller sensory epithelia devoid of innervation by Ma (2000)
10.1101/gad.840500 / Genes Dev / Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems by Liu (2000)
10.1242/dev.128.3.417 / Development / NeuroD-null mice are deaf due to a severe loss of the inner ear sensory neurons during development by Kim (2001)
10.1002/1096-9861(20010122)429:4<615::AID-CNE8>3.0.CO;2-F / J Comp Neurol / Transcription factor GATA-3 alters pathway selection of olivocochlear neurons and affects morphogenesis of the ear by Karis (2001)
10.1523/JNEUROSCI.20-16-06125.2000 / J Neurosci / Fgf/Fgfr-2 (IIIb) signaling is essential for inner ear morphogenesis by Pirvola (2000)
10.1038/12722 / Nat Genet / Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia by Xu (1999)
10.1007/s004410051244 / Cell Tissue Res / Making and breaking the innervation of the ear: neurotrophic support during ear development and its clinical implications by Fritzsch (1999)
10.1073/pnas.97.22.11692 / Proc Natl Acad Sci USA / Notch signaling in the development of the inner ear: lessons from Drosophila by Eddison (2000)
10.1097/00001756-200011270-00013 / Neuroreport / Developmental evolutionary biology of the vertebrate ear: conserving mechanoelectric transduction and developmental pathways in diverging morphologies by Fritzsch (2000)
10.1006/dbio.2001.0248 / Dev Biol / Lineage analysis in the chicken inner ear shows differences in clonal dispersion for epithelial, neuronal, and mesenchymal cells by Lang (2001)
10.1002/1096-9861(20000828)424:3<509::AID-CNE8>3.0.CO;2-Q / J Comp Neurol / Sensory organ generation in the chicken inner ear: contributions of bone morphogenetic protein 4, serrate 1, and lunatic fringe by Cole (2000)
10.1002/jmor.1051210302 / J Morphol / Correlation of the development of membranous and bony labyrinths, acoustics ganglia, nerves, and brain centers of the chick embryos by Knowlton (1967)
10.1006/dbio.1999.9457 / Dev Biol / Ectopic noggin blocks sensory and nonsensory organ morphogenesis in the chicken inner ear by Chang (1999)
10.1242/dev.127.1.45 / Development / Addition of the BMP4 antagonist, noggin, disrupts avian inner ear development by Gerlach (2000)
10.1242/dev.124.11.2245 / Development / A family of mammalian fringe genes implicated in boundary determination and the Notch pathway by Johnston (1997)
10.1038/28632 / Nature / lunatic fringe is an essential mediator of somite segmentation and patterning by Evrard (1998)
10.1038/43191 / Nature / Fringe modulates Notch–ligand interactions by Panin (1997)
10.1126/science.281.5385.2031 / Science / Dorsal–ventral signaling in the eye by Papayannopoulos (1998)
10.1038/28625 / Nature / Defects in somite formation in lunatic fringe-deficient mice by Zhang (1998)
10.1038/386366a0 / Nature / Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation by Laufer (1997)
10.1038/386360a0 / Nature / radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb by Rodriguez-Esteban (1997)
10.1073/pnas.071496998 / Proc Natl Acad Sci USA / The Notch ligand Jagged1 is required for inner ear sensory development by Kiernan (2001)
10.1093/hmg/10.5.507 / Hum Mol Genet / The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti by Tsai (2001)
10.1016/S0925-4773(99)00066-0 / Mech Dev / Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear by Morrison (1999)
10.1242/dev.117.1.13 / Development / Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear by Mansour (1993)
10.1016/S0378-5955(96)00093-7 / Hear Res / Regionalized expression of Nkx5-1, Nkx5-2, Pax2 and sek genes during mouse inner ear development by Rinkwitz-Brandt (1996)
10.1242/dev.122.11.3381 / Development / Pax2 contributes to inner ear patterning and optic nerve trajectory by Torres (1996)
10.1007/s004270100166 / Dev Genes Evol / Otx1 null mutants show partial segregation of sensory epithelia comparable to lamprey ears by Fritzsch (2001)
10.1242/dev.126.11.2335 / Development / Otx1 and Otx2 activities are required for the normal development of the mouse inner ear by Morsli (1999)
10.1006/dbio.2001.0211 / Dev Biol / Origins of inner ear sensory organs revealed by fate map and time-lapse analyses by Kil (2001)
10.1523/JNEUROSCI.18-19-07811.1998 / J Neurosci / Hair cells and supporting cells share a common progenitor in the avian inner ear by Fekete (1998)
10.1242/dev.125.23.4645 / Development / Cell fate choices and the expression of Notch, Delta and Serrate homologues in the chick inner ear: parallels with sense-organ development by Adam (1998)
10.1016/S0925-4773(98)00165-8 / Mech Dev / Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear by Lewis (1998)
10.1023/A:1007009803095 / J Neurocytol / Expression of proneural and neurogenic genes in the embryonic mammalian vestibular system by Shailam (1999)
10.1242/dev.127.15.3373 / Development / Notch signaling regulates the pattern of auditory hair cell differentiation in mammals by Zine (2000)
10.1523/JNEUROSCI.21-13-04712.2001 / J Neurosci / Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner normal development of the hair cells in the mammalian inner ear by Zine (2001)
10.1242/dev.127.21.4551 / Development / Hes1 is a negative regulator of inner ear hair cell differentiation by Zheng (2000)
10.1038/6804 / Nat Genet / Notch signalling pathway mediates hair cell development in mammalian cochlea by Lanford (1999)
10.1016/S0960-9822(00)00522-4 / Curr Biol / A mutation in the lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea by Zhang (2000)
10.1242/dev.126.24.5669 / Development / The deltaA gene of zebrafish mediates lateral inhibition of hair cells in the inner ear and is regulated by Pax2.1 by Riley (1999)
10.1242/dev.125.23.4637 / Development / Delta-Notch signalling and the patterning of sensory cell differentiation in the zebrafish ear: evidence from the mind bomb mutant by Haddon (1998)
10.1016/S0959-437X(97)80014-7 / Curr Opin Genet Dev / Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system by Kageyama (1997)
10.1016/S0959-4388(97)80115-8 / Curr Opin Neurobiol / Basic helix-loop-helix genes in neural development by Lee (1997)
10.1242/dev.127.13.2933 / Development / The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation by Bae (2000)
10.1007/s101620010023 / J Assoc Res Otolaryngol / Expression of Math1 and Hes5 in the cochleae of wildtype and Jag2 mutant mice by Lanford (2000)
10.1126/science.284.5421.1837 / Science / Math1: an essential gene for the generation of inner ear hair cells by Bermingham (1999)
10.1038/75753 / Nat Neurosci / Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears by Zheng (2000)
10.1038/381603a0 / Nature / Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development by Erkman (1996)
10.1073/pnas.94.17.9445 / Proc Natl Acad Sci USA / Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development by Xiang (1997)
10.1242/dev.125.20.3935 / Development / Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells by Xiang (1998)
10.1016/S0896-6273(00)80398-0 / Neuron / Differential distribution of Ca2+-activated K+ channel splice variants among hair cells along the tonotopic axis of the chick cochlea by Navaratnam (1997)
10.1016/S0896-6273(00)80397-9 / Neuron / Distribution of Ca2+-activated K+ channel isoforms along the tonotopic gradient of the chicken's cochlea by Rosenblatt (1997)

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 6:50 a.m.)
Deposited	4 years, 3 months ago (May 4, 2021, 4:22 p.m.)
Indexed	1 month, 3 weeks ago (July 11, 2025, 6:14 a.m.)
Issued	23 years, 7 months ago (Feb. 1, 2002)
Published	23 years, 7 months ago (Feb. 1, 2002)
Published Print	23 years, 7 months ago (Feb. 1, 2002)

Funders 0

None

BibTeX

@article{Fekete_2002, title={Revisiting cell fate specification in the inner ear}, volume={12}, ISSN={0959-4388}, url={http://dx.doi.org/10.1016/s0959-4388(02)00287-8}, DOI={10.1016/s0959-4388(02)00287-8}, number={1}, journal={Current Opinion in Neurobiology}, publisher={Elsevier BV}, author={Fekete, Donna M and Wu, Doris K}, year={2002}, month=feb, pages={35–42} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        7,
        11
      ]
    ],
    "date-time": "2025-07-11T10:14:11Z",
    "timestamp": 1752228851793
  },
  "reference-count": 65,
  "publisher": "Elsevier BV",
  "issue": "1",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2002,
            2,
            1
          ]
        ],
        "date-time": "2002-02-01T00:00:00Z",
        "timestamp": 1012521600000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2002,
        2
      ]
    ]
  },
  "DOI": "10.1016/s0959-4388(02)00287-8",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        25
      ]
    ],
    "date-time": "2002-07-25T10:50:10Z",
    "timestamp": 1027594210000
  },
  "page": "35-42",
  "source": "Crossref",
  "is-referenced-by-count": 239,
  "title": "Revisiting cell fate specification in the inner ear",
  "prefix": "10.1016",
  "volume": "12",
  "author": [
    {
      "given": "Donna M",
      "family": "Fekete",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Doris K",
      "family": "Wu",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB1",
      "doi-asserted-by": "crossref",
      "first-page": "533",
      "DOI": "10.1016/S0959-4388(96)80061-4",
      "article-title": "Cell fate specification in the inner ear",
      "volume": "6",
      "author": "Fekete",
      "year": "1996",
      "journal-title": "Curr Opin Neurobiol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB2",
      "doi-asserted-by": "crossref",
      "first-page": "3489",
      "DOI": "10.1242/dev.127.16.3489",
      "article-title": "Competence, specification and commitment in otic placode induction",
      "volume": "127",
      "author": "Groves",
      "year": "2000",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB3",
      "doi-asserted-by": "crossref",
      "first-page": "1965",
      "DOI": "10.1126/science.290.5498.1965",
      "article-title": "Identification of synergistic signals initiating inner ear development",
      "volume": "290",
      "author": "Ladher",
      "year": "2000",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB4",
      "doi-asserted-by": "crossref",
      "first-page": "2011",
      "DOI": "10.1242/dev.127.10.2011",
      "article-title": "Induction of inner ear fate by FGF3",
      "volume": "127",
      "author": "Vendrell",
      "year": "2000",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB5",
      "doi-asserted-by": "crossref",
      "first-page": "320",
      "DOI": "10.1016/S0168-9525(99)01774-6",
      "article-title": "Compartment boundaries: at the edge of development",
      "volume": "15",
      "author": "Dahmann",
      "year": "1999",
      "journal-title": "Trends Genet"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB6",
      "doi-asserted-by": "crossref",
      "first-page": "11700",
      "DOI": "10.1073/pnas.97.22.11700",
      "article-title": "Molecular genetics of pattern formation in the inner ear: do compartment boundaries play a role?",
      "volume": "97",
      "author": "Brigande",
      "year": "2000",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB7",
      "doi-asserted-by": "crossref",
      "first-page": "215",
      "DOI": "10.1006/dbio.1997.8716",
      "article-title": "The expression domain of two related homeobox genes defines a compartment in the chicken inner ear that may be involved in semicircular canal formation",
      "volume": "191",
      "author": "Kiernan",
      "year": "1997",
      "journal-title": "Dev Biol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB8",
      "doi-asserted-by": "crossref",
      "first-page": "189",
      "DOI": "10.1006/dbio.1998.9023",
      "article-title": "Regionalized organizing activity of the neural tube revealed by the regulation of lmx1 in the otic vesicle",
      "volume": "203",
      "author": "Giraldez",
      "year": "1998",
      "journal-title": "Dev Biol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB9",
      "doi-asserted-by": "crossref",
      "first-page": "645",
      "DOI": "10.1242/dev.125.4.645",
      "article-title": "Two regulatory genes, cNkx5-1 and cPax2, show different responses to local signals during otic placode and vesicle formation in the chick embryo",
      "volume": "125",
      "author": "Herbrand",
      "year": "1998",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB10",
      "doi-asserted-by": "crossref",
      "first-page": "795",
      "DOI": "10.1023/A:1007057719025",
      "article-title": "Expression of Pax2 and patterning of the chick inner ear",
      "volume": "28",
      "author": "Hutson",
      "year": "1999",
      "journal-title": "J Neurocytol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB11",
      "doi-asserted-by": "crossref",
      "first-page": "370",
      "DOI": "10.1006/dbio.1996.0081",
      "article-title": "The role of FGF-3 in early inner ear development: an analysis in normal and kreisler mutant mice",
      "volume": "174",
      "author": "McKay",
      "year": "1996",
      "journal-title": "Dev Biol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB12",
      "doi-asserted-by": "crossref",
      "first-page": "11",
      "DOI": "10.1242/dev.125.1.11",
      "article-title": "Axial specification for sensory organs versus non-sensory structures of the chicken inner ear",
      "volume": "125",
      "author": "Wu",
      "year": "1998",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB13",
      "doi-asserted-by": "crossref",
      "first-page": "256",
      "DOI": "10.1006/dbio.2000.9914",
      "article-title": "A fate map of chick otic cup closure reveals lineage boundaries in the dorsal otocyst",
      "volume": "227",
      "author": "Brigande",
      "year": "2000",
      "journal-title": "Dev Biol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB14",
      "doi-asserted-by": "crossref",
      "first-page": "129",
      "DOI": "10.1007/s101620010017",
      "article-title": "Neurogenin 1 null mutant ears develop fewer, morphologically normal hair cells in smaller sensory epithelia devoid of innervation",
      "volume": "1",
      "author": "Ma",
      "year": "2000",
      "journal-title": "JARO"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB15",
      "doi-asserted-by": "crossref",
      "first-page": "2839",
      "DOI": "10.1101/gad.840500",
      "article-title": "Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems",
      "volume": "14",
      "author": "Liu",
      "year": "2000",
      "journal-title": "Genes Dev"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB16",
      "doi-asserted-by": "crossref",
      "first-page": "417",
      "DOI": "10.1242/dev.128.3.417",
      "article-title": "NeuroD-null mice are deaf due to a severe loss of the inner ear sensory neurons during development",
      "volume": "128",
      "author": "Kim",
      "year": "2001",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB17",
      "doi-asserted-by": "crossref",
      "first-page": "615",
      "DOI": "10.1002/1096-9861(20010122)429:4<615::AID-CNE8>3.0.CO;2-F",
      "article-title": "Transcription factor GATA-3 alters pathway selection of olivocochlear neurons and affects morphogenesis of the ear",
      "volume": "429",
      "author": "Karis",
      "year": "2001",
      "journal-title": "J Comp Neurol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "6125",
      "DOI": "10.1523/JNEUROSCI.20-16-06125.2000",
      "article-title": "Fgf/Fgfr-2 (IIIb) signaling is essential for inner ear morphogenesis",
      "volume": "20",
      "author": "Pirvola",
      "year": "2000",
      "journal-title": "J Neurosci"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "113",
      "DOI": "10.1038/12722",
      "article-title": "Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia",
      "volume": "23",
      "author": "Xu",
      "year": "1999",
      "journal-title": "Nat Genet"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB20",
      "doi-asserted-by": "crossref",
      "first-page": "369",
      "DOI": "10.1007/s004410051244",
      "article-title": "Making and breaking the innervation of the ear: neurotrophic support during ear development and its clinical implications",
      "volume": "295",
      "author": "Fritzsch",
      "year": "1999",
      "journal-title": "Cell Tissue Res"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "11692",
      "DOI": "10.1073/pnas.97.22.11692",
      "article-title": "Notch signaling in the development of the inner ear: lessons from Drosophila",
      "volume": "97",
      "author": "Eddison",
      "year": "2000",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "R35",
      "DOI": "10.1097/00001756-200011270-00013",
      "article-title": "Developmental evolutionary biology of the vertebrate ear: conserving mechanoelectric transduction and developmental pathways in diverging morphologies",
      "volume": "11",
      "author": "Fritzsch",
      "year": "2000",
      "journal-title": "Neuroreport"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "120",
      "DOI": "10.1006/dbio.2001.0248",
      "article-title": "Lineage analysis in the chicken inner ear shows differences in clonal dispersion for epithelial, neuronal, and mesenchymal cells",
      "volume": "234",
      "author": "Lang",
      "year": "2001",
      "journal-title": "Dev Biol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "509",
      "DOI": "10.1002/1096-9861(20000828)424:3<509::AID-CNE8>3.0.CO;2-Q",
      "article-title": "Sensory organ generation in the chicken inner ear: contributions of bone morphogenetic protein 4, serrate 1, and lunatic fringe",
      "volume": "424",
      "author": "Cole",
      "year": "2000",
      "journal-title": "J Comp Neurol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "179",
      "DOI": "10.1002/jmor.1051210302",
      "article-title": "Correlation of the development of membranous and bony labyrinths, acoustics ganglia, nerves, and brain centers of the chick embryos",
      "volume": "121",
      "author": "Knowlton",
      "year": "1967",
      "journal-title": "J Morphol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "369",
      "DOI": "10.1006/dbio.1999.9457",
      "article-title": "Ectopic noggin blocks sensory and nonsensory organ morphogenesis in the chicken inner ear",
      "volume": "216",
      "author": "Chang",
      "year": "1999",
      "journal-title": "Dev Biol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "45",
      "DOI": "10.1242/dev.127.1.45",
      "article-title": "Addition of the BMP4 antagonist, noggin, disrupts avian inner ear development",
      "volume": "127",
      "author": "Gerlach",
      "year": "2000",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "2245",
      "DOI": "10.1242/dev.124.11.2245",
      "article-title": "A family of mammalian fringe genes implicated in boundary determination and the Notch pathway",
      "volume": "124",
      "author": "Johnston",
      "year": "1997",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "377",
      "DOI": "10.1038/28632",
      "article-title": "lunatic fringe is an essential mediator of somite segmentation and patterning",
      "volume": "394",
      "author": "Evrard",
      "year": "1998",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "908",
      "DOI": "10.1038/43191",
      "article-title": "Fringe modulates Notch\u2013ligand interactions",
      "volume": "387",
      "author": "Panin",
      "year": "1997",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "2031",
      "DOI": "10.1126/science.281.5385.2031",
      "article-title": "Dorsal\u2013ventral signaling in the eye",
      "volume": "281",
      "author": "Papayannopoulos",
      "year": "1998",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "374",
      "DOI": "10.1038/28625",
      "article-title": "Defects in somite formation in lunatic fringe-deficient mice",
      "volume": "394",
      "author": "Zhang",
      "year": "1998",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "366",
      "DOI": "10.1038/386366a0",
      "article-title": "Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation",
      "volume": "386",
      "author": "Laufer",
      "year": "1997",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "360",
      "DOI": "10.1038/386360a0",
      "article-title": "radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb",
      "volume": "386",
      "author": "Rodriguez-Esteban",
      "year": "1997",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "3873",
      "DOI": "10.1073/pnas.071496998",
      "article-title": "The Notch ligand Jagged1 is required for inner ear sensory development",
      "volume": "98",
      "author": "Kiernan",
      "year": "2001",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "507",
      "DOI": "10.1093/hmg/10.5.507",
      "article-title": "The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti",
      "volume": "10",
      "author": "Tsai",
      "year": "2001",
      "journal-title": "Hum Mol Genet"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "169",
      "DOI": "10.1016/S0925-4773(99)00066-0",
      "article-title": "Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear",
      "volume": "84",
      "author": "Morrison",
      "year": "1999",
      "journal-title": "Mech Dev"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "13",
      "DOI": "10.1242/dev.117.1.13",
      "article-title": "Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear",
      "volume": "117",
      "author": "Mansour",
      "year": "1993",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "129",
      "DOI": "10.1016/S0378-5955(96)00093-7",
      "article-title": "Regionalized expression of Nkx5-1, Nkx5-2, Pax2 and sek genes during mouse inner ear development",
      "volume": "99",
      "author": "Rinkwitz-Brandt",
      "year": "1996",
      "journal-title": "Hear Res"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "3381",
      "DOI": "10.1242/dev.122.11.3381",
      "article-title": "Pax2 contributes to inner ear patterning and optic nerve trajectory",
      "volume": "122",
      "author": "Torres",
      "year": "1996",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "388",
      "DOI": "10.1007/s004270100166",
      "article-title": "Otx1 null mutants show partial segregation of sensory epithelia comparable to lamprey ears",
      "volume": "211",
      "author": "Fritzsch",
      "year": "2001",
      "journal-title": "Dev Genes Evol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "2335",
      "DOI": "10.1242/dev.126.11.2335",
      "article-title": "Otx1 and Otx2 activities are required for the normal development of the mouse inner ear",
      "volume": "126",
      "author": "Morsli",
      "year": "1999",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "365",
      "DOI": "10.1006/dbio.2001.0211",
      "article-title": "Origins of inner ear sensory organs revealed by fate map and time-lapse analyses",
      "volume": "233",
      "author": "Kil",
      "year": "2001",
      "journal-title": "Dev Biol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "7811",
      "DOI": "10.1523/JNEUROSCI.18-19-07811.1998",
      "article-title": "Hair cells and supporting cells share a common progenitor in the avian inner ear",
      "volume": "18",
      "author": "Fekete",
      "year": "1998",
      "journal-title": "J Neurosci"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "4645",
      "DOI": "10.1242/dev.125.23.4645",
      "article-title": "Cell fate choices and the expression of Notch, Delta and Serrate homologues in the chick inner ear: parallels with sense-organ development",
      "volume": "125",
      "author": "Adam",
      "year": "1998",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "159",
      "DOI": "10.1016/S0925-4773(98)00165-8",
      "article-title": "Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear",
      "volume": "78",
      "author": "Lewis",
      "year": "1998",
      "journal-title": "Mech Dev"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "809",
      "DOI": "10.1023/A:1007009803095",
      "article-title": "Expression of proneural and neurogenic genes in the embryonic mammalian vestibular system",
      "volume": "28",
      "author": "Shailam",
      "year": "1999",
      "journal-title": "J Neurocytol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "3373",
      "DOI": "10.1242/dev.127.15.3373",
      "article-title": "Notch signaling regulates the pattern of auditory hair cell differentiation in mammals",
      "volume": "127",
      "author": "Zine",
      "year": "2000",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "4712",
      "DOI": "10.1523/JNEUROSCI.21-13-04712.2001",
      "article-title": "Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner normal development of the hair cells in the mammalian inner ear",
      "volume": "21",
      "author": "Zine",
      "year": "2001",
      "journal-title": "J Neurosci"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB50",
      "doi-asserted-by": "crossref",
      "first-page": "4551",
      "DOI": "10.1242/dev.127.21.4551",
      "article-title": "Hes1 is a negative regulator of inner ear hair cell differentiation",
      "volume": "127",
      "author": "Zheng",
      "year": "2000",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB51",
      "doi-asserted-by": "crossref",
      "first-page": "289",
      "DOI": "10.1038/6804",
      "article-title": "Notch signalling pathway mediates hair cell development in mammalian cochlea",
      "volume": "21",
      "author": "Lanford",
      "year": "1999",
      "journal-title": "Nat Genet"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB52",
      "doi-asserted-by": "crossref",
      "first-page": "659",
      "DOI": "10.1016/S0960-9822(00)00522-4",
      "article-title": "A mutation in the lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea",
      "volume": "10",
      "author": "Zhang",
      "year": "2000",
      "journal-title": "Curr Biol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB53",
      "doi-asserted-by": "crossref",
      "first-page": "5669",
      "DOI": "10.1242/dev.126.24.5669",
      "article-title": "The deltaA gene of zebrafish mediates lateral inhibition of hair cells in the inner ear and is regulated by Pax2.1",
      "volume": "126",
      "author": "Riley",
      "year": "1999",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB54",
      "doi-asserted-by": "crossref",
      "first-page": "4637",
      "DOI": "10.1242/dev.125.23.4637",
      "article-title": "Delta-Notch signalling and the patterning of sensory cell differentiation in the zebrafish ear: evidence from the mind bomb mutant",
      "volume": "125",
      "author": "Haddon",
      "year": "1998",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB55",
      "doi-asserted-by": "crossref",
      "first-page": "659",
      "DOI": "10.1016/S0959-437X(97)80014-7",
      "article-title": "Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system",
      "volume": "7",
      "author": "Kageyama",
      "year": "1997",
      "journal-title": "Curr Opin Genet Dev"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB56",
      "doi-asserted-by": "crossref",
      "first-page": "13",
      "DOI": "10.1016/S0959-4388(97)80115-8",
      "article-title": "Basic helix-loop-helix genes in neural development",
      "volume": "7",
      "author": "Lee",
      "year": "1997",
      "journal-title": "Curr Opin Neurobiol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB57",
      "doi-asserted-by": "crossref",
      "first-page": "2933",
      "DOI": "10.1242/dev.127.13.2933",
      "article-title": "The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation",
      "volume": "127",
      "author": "Bae",
      "year": "2000",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB58",
      "doi-asserted-by": "crossref",
      "first-page": "161",
      "DOI": "10.1007/s101620010023",
      "article-title": "Expression of Math1 and Hes5 in the cochleae of wildtype and Jag2 mutant mice",
      "volume": "1",
      "author": "Lanford",
      "year": "2000",
      "journal-title": "J Assoc Res Otolaryngol"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB59",
      "doi-asserted-by": "crossref",
      "first-page": "1837",
      "DOI": "10.1126/science.284.5421.1837",
      "article-title": "Math1: an essential gene for the generation of inner ear hair cells",
      "volume": "284",
      "author": "Bermingham",
      "year": "1999",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB60",
      "doi-asserted-by": "crossref",
      "first-page": "580",
      "DOI": "10.1038/75753",
      "article-title": "Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears",
      "volume": "3",
      "author": "Zheng",
      "year": "2000",
      "journal-title": "Nat Neurosci"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB61",
      "doi-asserted-by": "crossref",
      "first-page": "603",
      "DOI": "10.1038/381603a0",
      "article-title": "Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development",
      "volume": "381",
      "author": "Erkman",
      "year": "1996",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB62",
      "doi-asserted-by": "crossref",
      "first-page": "9445",
      "DOI": "10.1073/pnas.94.17.9445",
      "article-title": "Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development",
      "volume": "94",
      "author": "Xiang",
      "year": "1997",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB63",
      "doi-asserted-by": "crossref",
      "first-page": "3935",
      "DOI": "10.1242/dev.125.20.3935",
      "article-title": "Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells",
      "volume": "125",
      "author": "Xiang",
      "year": "1998",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB64",
      "doi-asserted-by": "crossref",
      "first-page": "1077",
      "DOI": "10.1016/S0896-6273(00)80398-0",
      "article-title": "Differential distribution of Ca2+-activated K+ channel splice variants among hair cells along the tonotopic axis of the chick cochlea",
      "volume": "19",
      "author": "Navaratnam",
      "year": "1997",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/S0959-4388(02)00287-8_BIB65",
      "doi-asserted-by": "crossref",
      "first-page": "1061",
      "DOI": "10.1016/S0896-6273(00)80397-9",
      "article-title": "Distribution of Ca2+-activated K+ channel isoforms along the tonotopic gradient of the chicken's cochlea",
      "volume": "19",
      "author": "Rosenblatt",
      "year": "1997",
      "journal-title": "Neuron"
    }
  ],
  "container-title": "Current Opinion in Neurobiology",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0959438802002878?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0959438802002878?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2021,
        5,
        4
      ]
    ],
    "date-time": "2021-05-04T20:22:25Z",
    "timestamp": 1620159745000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0959438802002878"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2002,
        2
      ]
    ]
  },
  "references-count": 65,
  "journal-issue": {
    "issue": "1",
    "published-print": {
      "date-parts": [
        [
          2002,
          2
        ]
      ]
    }
  },
  "alternative-id": [
    "S0959438802002878"
  ],
  "URL": "http://dx.doi.org/10.1016/S0959-4388(02)00287-8",
  "relation": {},
  "ISSN": [
    "0959-4388"
  ],
  "subject": [],
  "container-title-short": "Current Opinion in Neurobiology",
  "published": {
    "date-parts": [
      [
        2002,
        2
      ]
    ]
  }
}