DOI: 10.1016/s0955-0674(99)00075-7. Protein phosphatases and the regulation of mitogen-activated protein kinase signalling

Protein phosphatases and the regulation of mitogen-activated protein kinase signalling

10.1016/s0955-0674(99)00075-7

Crossref journal-article

Elsevier BV

Current Opinion in Cell Biology (78)

Bibliography

Keyse, S. M. (2000). Protein phosphatases and the regulation of mitogen-activated protein kinase signalling. Current Opinion in Cell Biology, 12(2), 186â192.

Authors 1

Stephen M Keyse (first)

References 49 Referenced 656

10.1016/S0955-0674(97)80061-0 / Curr Opin Cell Biol / Mitogen-activated protein kinase pathways by Robinson (1997)
10.1016/S0962-8924(97)01105-7 / Trends Cell Biol / The search for physiological substrates of the MAP and SAP kinases in mammalian cells by Cohen (1997)
10.1016/S0955-0674(99)80028-3 / Curr Opin Cell Biol / Organisation and regulation of mitogen-activated protein kinase signalling pathways by Garrington (1999)
10.1016/0092-8674(95)90401-8 / Cell / Specificity of receptor tyrosine kinase signalling: transient versus sustained extracellular signal regulated kinase activation by Marshall (1995)
10.1016/0968-0004(93)90092-2 / Trends Biochem Sci / Amino acid similarity between CL100, a dual specificity MAP kinase phosphatase and cdc25 by Keyse (1993)
10.1016/0167-4889(94)00211-V / Biochim Biophys Acta / An emerging family of dual-specificity MAP kinase phosphatases by Keyse (1995)
{'key': '10.1016/S0955-0674(99)00075-7_BIB7', 'first-page': '2015', 'article-title': 'The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts', 'volume': '8', 'author': 'Alessi', 'year': '1993', 'journal-title': 'Oncogene'} / Oncogene / The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts by Alessi (1993)
10.1016/0092-8674(93)90383-2 / Cell / MKP-1(3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo by Sun (1993)
10.1038/367651a0 / Nature / Control of MAP kinase activation by the mitogen induced threonine/tyrosine phosphatase PAC-1 by Ward (1994)
10.1002/j.1460-2075.1996.tb00731.x / EMBO J / Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytoplasmic dual-specificity phosphatase by Groom (1996)
10.1074/jbc.271.44.27205 / J Biol Chem / The dual specificity phosphatases M3/6 and MKP-3 are highly selective for the inactivation of distinct mitogen-activated protein kinases by Muda (1996)
10.1074/jbc.273.15.9323 / J Biol Chem / The mitogen-activated protein-kinase phosphatase-3 N-terminal noncatalytic region is responsible for tight substrate-binding and enzymatic specificity by Muda (1998)
10.1126/science.280.5367.1262 / Science / Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase by Camps (1998)
10.1242/jcs.111.22.3389 / J Cell Sci / Isolation of the human genes encoding the Pyst1 and Pyst2 phosphatases: characterisation of Pyst2 as a cytosolic dual-specificity MAP kinase phosphatase and its catalytic activation by both MAP and SAP kinases by Dowd (1998)
10.1074/jbc.274.28.19949 / J Biol Chem / Molecular cloning and characterisation of a novel dual specificity phosphatase, MKP-5 by Tanoue (1999)
10.1038/5861 / Nat Struct Biol / Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation by Stewart (1999)
10.1126/science.272.5266.1328 / Science / Crystal structure of the dual-specificity protein phosphatase VHR by Yuvaniyama (1996)
10.1016/S0968-0004(96)10059-1 / Trends Biochem Sci / Structure and function of the protein tyrosine phosphatases by Fauman (1996)
10.1073/pnas.93.6.2493 / Proc Natl Acad Sci USA / Visualisation of intermediate and transition-state structures in protein tyrosine phosphatase catalysis by Denu (1996)
{'key': '10.1016/S0955-0674(99)00075-7_BIB20', 'first-page': '925', 'article-title': 'Disruption of the erp/mkp-1 gene does not affect mouse development: normal MAP kinase activity in ERP/MKP-1-deficient fibroblasts', 'volume': '13', 'author': 'Dorfman', 'year': '1996', 'journal-title': 'Oncogene'} / Oncogene / Disruption of the erp/mkp-1 gene does not affect mouse development: normal MAP kinase activity in ERP/MKP-1-deficient fibroblasts by Dorfman (1996)
10.1002/j.1460-2075.1994.tb06235.x / EMBO J / MSG5, a novel protein phosphatase promotes adaptation to pheromone by Doi (1994)
10.1091/mbc.8.12.2539 / Mol Biol Cell / Derepressed hyphal growth and reduced virulence in a VH1 family-related protein phosphatase mutant of the human pathogen Candida albicans by Csank (1997)
10.1093/emboj/17.1.140 / EMBO J / pmp1+, a suppressor of calcineurin deficiency, encodes a novel MAP kinase phosphatase in fission yeast by Sugiura (1998)
10.1101/gad.10.21.2745 / Genes Dev / A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila by Sluss (1996)
10.1242/dev.119.Supplement.251 / Development / puckered, a gene involved in position-specific cell differentiation in the dorsal epidermis by Ring (1993)
10.1101/gad.12.4.557 / Genes Dev / puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila by Martin-Blanco (1998)
10.1128/MCB.17.3.1289 / Mol Cell Biol / Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein-kinase by the PTP2 and PTP3 protein-tyrosine phosphatases by Wurgler-Murphy (1997)
10.1074/jbc.272.28.17749 / J Biol Chem / 2 protein-tyrosine phosphatases inactivate the osmotic-stress response pathway in yeast by targeting the mitogen-activated protein kinase, Hog1 by Jacoby (1997)
10.1101/gad.11.13.1690 / Genes Dev / Differential regulation of FUS3 map kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase Msg5 in Saccharomyces-cerevisiae by Zhan (1997)
10.1101/gad.9.17.2117 / Genes Dev / Pyp1 and pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell-size at division in fission yeast by Millar (1995)
10.1038/378739a0 / Nature / Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast by Shiozaki (1995)
10.1093/emboj/17.24.7337 / EMBO J / PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif by Pulido (1998)
10.1006/bbrc.1999.0278 / Biochem Biophys Res Commun / Inactivation of mitogen-activated protein kinases by a mammalian tyrosine-specific enzyme by Ogata (1999)
10.1074/jbc.273.25.15340 / J Biol Chem / Negative regulation of T cell antigen receptor signal transduction by hematopoietic tyrosine phosphatase (HePTP) by Saxena (1998)
10.1074/jbc.274.17.11693 / J Biol Chem / Inhibition of T cell signalling by mitogen-activated protein kinase-targeted hematopoietic tyrosine phosphatase (HePTP) by Saxena (1999)
10.4049/jimmunol.163.3.1282 / J Immunol / Direct suppression of TCR-mediated activation of extracellular signal-regulated kinase by leukocyte protein tyrosine phosphatase, a tyrosine-specific phosphatase by Oh-hora (1999)
10.1074/jbc.274.31.21900 / J Biol Chem / Interaction of mitogen-activated protein kinases with the kinase interaction motif of the tyrosine phosphatase PTP-SL provides substrate specificity and retains ERK2 in the cytoplasm by Zuniga (1999)
10.1038/13024 / Nat Cell Biol / Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase by Saxena (1999)
{'key': '10.1016/S0955-0674(99)00075-7_BIB39', 'first-page': '49', 'article-title': 'A neuronal protein tyrosine phosphatase induced by nerve growth factor', 'volume': '270', 'author': 'Sharma', 'year': '1995', 'journal-title': 'Proc Natl Acad Sci USA'} / Proc Natl Acad Sci USA / A neuronal protein tyrosine phosphatase induced by nerve growth factor by Sharma (1995)
10.1016/S1097-2765(01)80006-X / Mol Cell / PTP-ER, a novel tyrosine phospatase, functions downstream of Ras1 to downregulate MAP kinase during Drosophila eye development by Karim (1999)
10.1074/jbc.274.19.13271 / J Biol Chem / Extracellular regulated kinases (ERK)1 and ERK2 are authentic substrates for the dual-specificity protein-tyrosine phosphatase VHR by Todd (1999)
10.1016/S0960-9822(95)00059-5 / Curr Biol / Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100 in various cell lines by Alessi (1995)
10.1093/emboj/17.16.4744 / EMBO J / Protein phosphatase 2Cα inhibits the human stress-responsive p38 and JNK MAPK pathways by Takekawa (1998)
10.1093/emboj/18.3.664 / EMBO J / Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry by Brunet (1999)
10.1016/0092-8674(94)90362-X / Cell / A gain-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase pathways by Brunner (1994)
10.1016/0014-5793(94)00958-9 / FEBS Lett / The sevenmaker gain-of-function mutation in p42 MAP kinase leads to enhanced signalling and reduced sensitivity to dual-specificity phosphatase action by Bott (1995)
10.1074/jbc.271.11.6497 / J Biol Chem / The mitogen-activated protein kinase phosphatases PAC1, MKP-1 and MKP-2 have unique substrate specificities and reduced activity in vivo towards the ERK2 sevenmaker mutation by Chu (1996)
10.1126/science.286.5449.2514 / Science / Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation by Brondello (1999)
10.1101/gad.13.21.2811 / Genes Dev / A specific protein–protein interaction accounts for the in vivo substrate selectivity of Ptp3 towards the Fus3 MAP kinase by Zhan (1999)

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 9:52 p.m.)
Deposited	2 years, 4 months ago (April 16, 2023, 2:55 p.m.)
Indexed	2 days, 2 hours ago (Aug. 28, 2025, 8:51 a.m.)
Issued	25 years, 4 months ago (April 1, 2000)
Published	25 years, 4 months ago (April 1, 2000)
Published Print	25 years, 4 months ago (April 1, 2000)

Funders 0

None

BibTeX

@article{Keyse_2000, title={Protein phosphatases and the regulation of mitogen-activated protein kinase signalling}, volume={12}, ISSN={0955-0674}, url={http://dx.doi.org/10.1016/s0955-0674(99)00075-7}, DOI={10.1016/s0955-0674(99)00075-7}, number={2}, journal={Current Opinion in Cell Biology}, publisher={Elsevier BV}, author={Keyse, Stephen M}, year={2000}, month=apr, pages={186–192} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        28
      ]
    ],
    "date-time": "2025-08-28T12:51:26Z",
    "timestamp": 1756385486077
  },
  "reference-count": 49,
  "publisher": "Elsevier BV",
  "issue": "2",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2000,
            4,
            1
          ]
        ],
        "date-time": "2000-04-01T00:00:00Z",
        "timestamp": 954547200000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2000,
        4
      ]
    ]
  },
  "DOI": "10.1016/s0955-0674(99)00075-7",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        26
      ]
    ],
    "date-time": "2002-07-26T01:52:44Z",
    "timestamp": 1027648364000
  },
  "page": "186-192",
  "source": "Crossref",
  "is-referenced-by-count": 656,
  "title": "Protein phosphatases and the regulation of mitogen-activated protein kinase signalling",
  "prefix": "10.1016",
  "volume": "12",
  "author": [
    {
      "given": "Stephen M",
      "family": "Keyse",
      "sequence": "first",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB1",
      "doi-asserted-by": "crossref",
      "first-page": "180",
      "DOI": "10.1016/S0955-0674(97)80061-0",
      "article-title": "Mitogen-activated protein kinase pathways",
      "volume": "9",
      "author": "Robinson",
      "year": "1997",
      "journal-title": "Curr Opin Cell Biol"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB2",
      "doi-asserted-by": "crossref",
      "first-page": "353",
      "DOI": "10.1016/S0962-8924(97)01105-7",
      "article-title": "The search for physiological substrates of the MAP and SAP kinases in mammalian cells",
      "volume": "7",
      "author": "Cohen",
      "year": "1997",
      "journal-title": "Trends Cell Biol"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB3",
      "doi-asserted-by": "crossref",
      "first-page": "211",
      "DOI": "10.1016/S0955-0674(99)80028-3",
      "article-title": "Organisation and regulation of mitogen-activated protein kinase signalling pathways",
      "volume": "11",
      "author": "Garrington",
      "year": "1999",
      "journal-title": "Curr Opin Cell Biol"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB4",
      "doi-asserted-by": "crossref",
      "first-page": "179",
      "DOI": "10.1016/0092-8674(95)90401-8",
      "article-title": "Specificity of receptor tyrosine kinase signalling: transient versus sustained extracellular signal regulated kinase activation",
      "volume": "80",
      "author": "Marshall",
      "year": "1995",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB5",
      "doi-asserted-by": "crossref",
      "first-page": "377",
      "DOI": "10.1016/0968-0004(93)90092-2",
      "article-title": "Amino acid similarity between CL100, a dual specificity MAP kinase phosphatase and cdc25",
      "volume": "18",
      "author": "Keyse",
      "year": "1993",
      "journal-title": "Trends Biochem Sci"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB6",
      "doi-asserted-by": "crossref",
      "first-page": "152",
      "DOI": "10.1016/0167-4889(94)00211-V",
      "article-title": "An emerging family of dual-specificity MAP kinase phosphatases",
      "volume": "1265",
      "author": "Keyse",
      "year": "1995",
      "journal-title": "Biochim Biophys Acta"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB7",
      "first-page": "2015",
      "article-title": "The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts",
      "volume": "8",
      "author": "Alessi",
      "year": "1993",
      "journal-title": "Oncogene"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB8",
      "doi-asserted-by": "crossref",
      "first-page": "487",
      "DOI": "10.1016/0092-8674(93)90383-2",
      "article-title": "MKP-1(3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo",
      "volume": "75",
      "author": "Sun",
      "year": "1993",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB9",
      "doi-asserted-by": "crossref",
      "first-page": "651",
      "DOI": "10.1038/367651a0",
      "article-title": "Control of MAP kinase activation by the mitogen induced threonine/tyrosine phosphatase PAC-1",
      "volume": "367",
      "author": "Ward",
      "year": "1994",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB10",
      "doi-asserted-by": "crossref",
      "first-page": "3621",
      "DOI": "10.1002/j.1460-2075.1996.tb00731.x",
      "article-title": "Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytoplasmic dual-specificity phosphatase",
      "volume": "15",
      "author": "Groom",
      "year": "1996",
      "journal-title": "EMBO J"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB11",
      "doi-asserted-by": "crossref",
      "first-page": "27205",
      "DOI": "10.1074/jbc.271.44.27205",
      "article-title": "The dual specificity phosphatases M3/6 and MKP-3 are highly selective for the inactivation of distinct mitogen-activated protein kinases",
      "volume": "271",
      "author": "Muda",
      "year": "1996",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB12",
      "doi-asserted-by": "crossref",
      "first-page": "9323",
      "DOI": "10.1074/jbc.273.15.9323",
      "article-title": "The mitogen-activated protein-kinase phosphatase-3 N-terminal noncatalytic region is responsible for tight substrate-binding and enzymatic specificity",
      "volume": "273",
      "author": "Muda",
      "year": "1998",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB13",
      "doi-asserted-by": "crossref",
      "first-page": "1262",
      "DOI": "10.1126/science.280.5367.1262",
      "article-title": "Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase",
      "volume": "280",
      "author": "Camps",
      "year": "1998",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB14",
      "doi-asserted-by": "crossref",
      "first-page": "3389",
      "DOI": "10.1242/jcs.111.22.3389",
      "article-title": "Isolation of the human genes encoding the Pyst1 and Pyst2 phosphatases: characterisation of Pyst2 as a cytosolic dual-specificity MAP kinase phosphatase and its catalytic activation by both MAP and SAP kinases",
      "volume": "111",
      "author": "Dowd",
      "year": "1998",
      "journal-title": "J Cell Sci"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB15",
      "doi-asserted-by": "crossref",
      "first-page": "19949",
      "DOI": "10.1074/jbc.274.28.19949",
      "article-title": "Molecular cloning and characterisation of a novel dual specificity phosphatase, MKP-5",
      "volume": "274",
      "author": "Tanoue",
      "year": "1999",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB16",
      "doi-asserted-by": "crossref",
      "first-page": "174",
      "DOI": "10.1038/5861",
      "article-title": "Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation",
      "volume": "6",
      "author": "Stewart",
      "year": "1999",
      "journal-title": "Nat Struct Biol"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB17",
      "doi-asserted-by": "crossref",
      "first-page": "1328",
      "DOI": "10.1126/science.272.5266.1328",
      "article-title": "Crystal structure of the dual-specificity protein phosphatase VHR",
      "volume": "272",
      "author": "Yuvaniyama",
      "year": "1996",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "413",
      "DOI": "10.1016/S0968-0004(96)10059-1",
      "article-title": "Structure and function of the protein tyrosine phosphatases",
      "volume": "21",
      "author": "Fauman",
      "year": "1996",
      "journal-title": "Trends Biochem Sci"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "2493",
      "DOI": "10.1073/pnas.93.6.2493",
      "article-title": "Visualisation of intermediate and transition-state structures in protein tyrosine phosphatase catalysis",
      "volume": "93",
      "author": "Denu",
      "year": "1996",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB20",
      "first-page": "925",
      "article-title": "Disruption of the erp/mkp-1 gene does not affect mouse development: normal MAP kinase activity in ERP/MKP-1-deficient fibroblasts",
      "volume": "13",
      "author": "Dorfman",
      "year": "1996",
      "journal-title": "Oncogene"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "61",
      "DOI": "10.1002/j.1460-2075.1994.tb06235.x",
      "article-title": "MSG5, a novel protein phosphatase promotes adaptation to pheromone",
      "volume": "13",
      "author": "Doi",
      "year": "1994",
      "journal-title": "EMBO J"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "2539",
      "DOI": "10.1091/mbc.8.12.2539",
      "article-title": "Derepressed hyphal growth and reduced virulence in a VH1 family-related protein phosphatase mutant of the human pathogen Candida albicans",
      "volume": "8",
      "author": "Csank",
      "year": "1997",
      "journal-title": "Mol Biol Cell"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "140",
      "DOI": "10.1093/emboj/17.1.140",
      "article-title": "pmp1+, a suppressor of calcineurin deficiency, encodes a novel MAP kinase phosphatase in fission yeast",
      "volume": "17",
      "author": "Sugiura",
      "year": "1998",
      "journal-title": "EMBO J"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "2745",
      "DOI": "10.1101/gad.10.21.2745",
      "article-title": "A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila",
      "volume": "10",
      "author": "Sluss",
      "year": "1996",
      "journal-title": "Genes Dev"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "251",
      "DOI": "10.1242/dev.119.Supplement.251",
      "article-title": "puckered, a gene involved in position-specific cell differentiation in the dorsal epidermis",
      "volume": "19",
      "author": "Ring",
      "year": "1993",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "557",
      "DOI": "10.1101/gad.12.4.557",
      "article-title": "puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila",
      "volume": "12",
      "author": "Martin-Blanco",
      "year": "1998",
      "journal-title": "Genes Dev"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "1289",
      "DOI": "10.1128/MCB.17.3.1289",
      "article-title": "Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein-kinase by the PTP2 and PTP3 protein-tyrosine phosphatases",
      "volume": "17",
      "author": "Wurgler-Murphy",
      "year": "1997",
      "journal-title": "Mol Cell Biol"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "17749",
      "DOI": "10.1074/jbc.272.28.17749",
      "article-title": "2 protein-tyrosine phosphatases inactivate the osmotic-stress response pathway in yeast by targeting the mitogen-activated protein kinase, Hog1",
      "volume": "272",
      "author": "Jacoby",
      "year": "1997",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "1690",
      "DOI": "10.1101/gad.11.13.1690",
      "article-title": "Differential regulation of FUS3 map kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase Msg5 in Saccharomyces-cerevisiae",
      "volume": "11",
      "author": "Zhan",
      "year": "1997",
      "journal-title": "Genes Dev"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "2117",
      "DOI": "10.1101/gad.9.17.2117",
      "article-title": "Pyp1 and pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell-size at division in fission yeast",
      "volume": "9",
      "author": "Millar",
      "year": "1995",
      "journal-title": "Genes Dev"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "739",
      "DOI": "10.1038/378739a0",
      "article-title": "Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast",
      "volume": "378",
      "author": "Shiozaki",
      "year": "1995",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "7337",
      "DOI": "10.1093/emboj/17.24.7337",
      "article-title": "PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif",
      "volume": "17",
      "author": "Pulido",
      "year": "1998",
      "journal-title": "EMBO J"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "52",
      "DOI": "10.1006/bbrc.1999.0278",
      "article-title": "Inactivation of mitogen-activated protein kinases by a mammalian tyrosine-specific enzyme",
      "volume": "256",
      "author": "Ogata",
      "year": "1999",
      "journal-title": "Biochem Biophys Res Commun"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "15340",
      "DOI": "10.1074/jbc.273.25.15340",
      "article-title": "Negative regulation of T cell antigen receptor signal transduction by hematopoietic tyrosine phosphatase (HePTP)",
      "volume": "273",
      "author": "Saxena",
      "year": "1998",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "11693",
      "DOI": "10.1074/jbc.274.17.11693",
      "article-title": "Inhibition of T cell signalling by mitogen-activated protein kinase-targeted hematopoietic tyrosine phosphatase (HePTP)",
      "volume": "274",
      "author": "Saxena",
      "year": "1999",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "1282",
      "DOI": "10.4049/jimmunol.163.3.1282",
      "article-title": "Direct suppression of TCR-mediated activation of extracellular signal-regulated kinase by leukocyte protein tyrosine phosphatase, a tyrosine-specific phosphatase",
      "volume": "163",
      "author": "Oh-hora",
      "year": "1999",
      "journal-title": "J Immunol"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "21900",
      "DOI": "10.1074/jbc.274.31.21900",
      "article-title": "Interaction of mitogen-activated protein kinases with the kinase interaction motif of the tyrosine phosphatase PTP-SL provides substrate specificity and retains ERK2 in the cytoplasm",
      "volume": "274",
      "author": "Zuniga",
      "year": "1999",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "305",
      "DOI": "10.1038/13024",
      "article-title": "Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase",
      "volume": "1",
      "author": "Saxena",
      "year": "1999",
      "journal-title": "Nat Cell Biol"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB39",
      "first-page": "49",
      "article-title": "A neuronal protein tyrosine phosphatase induced by nerve growth factor",
      "volume": "270",
      "author": "Sharma",
      "year": "1995",
      "journal-title": "Proc Natl Acad Sci USA"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "741",
      "DOI": "10.1016/S1097-2765(01)80006-X",
      "article-title": "PTP-ER, a novel tyrosine phospatase, functions downstream of Ras1 to downregulate MAP kinase during Drosophila eye development",
      "volume": "3",
      "author": "Karim",
      "year": "1999",
      "journal-title": "Mol Cell"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "13271",
      "DOI": "10.1074/jbc.274.19.13271",
      "article-title": "Extracellular regulated kinases (ERK)1 and ERK2 are authentic substrates for the dual-specificity protein-tyrosine phosphatase VHR",
      "volume": "274",
      "author": "Todd",
      "year": "1999",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "283",
      "DOI": "10.1016/S0960-9822(95)00059-5",
      "article-title": "Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100 in various cell lines",
      "volume": "5",
      "author": "Alessi",
      "year": "1995",
      "journal-title": "Curr Biol"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "4744",
      "DOI": "10.1093/emboj/17.16.4744",
      "article-title": "Protein phosphatase 2C\u03b1 inhibits the human stress-responsive p38 and JNK MAPK pathways",
      "volume": "17",
      "author": "Takekawa",
      "year": "1998",
      "journal-title": "EMBO J"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "664",
      "DOI": "10.1093/emboj/18.3.664",
      "article-title": "Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry",
      "volume": "18",
      "author": "Brunet",
      "year": "1999",
      "journal-title": "EMBO J"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "875",
      "DOI": "10.1016/0092-8674(94)90362-X",
      "article-title": "A gain-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase pathways",
      "volume": "76",
      "author": "Brunner",
      "year": "1994",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "201",
      "DOI": "10.1016/0014-5793(94)00958-9",
      "article-title": "The sevenmaker gain-of-function mutation in p42 MAP kinase leads to enhanced signalling and reduced sensitivity to dual-specificity phosphatase action",
      "volume": "352",
      "author": "Bott",
      "year": "1995",
      "journal-title": "FEBS Lett"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "6497",
      "DOI": "10.1074/jbc.271.11.6497",
      "article-title": "The mitogen-activated protein kinase phosphatases PAC1, MKP-1 and MKP-2 have unique substrate specificities and reduced activity in vivo towards the ERK2 sevenmaker mutation",
      "volume": "271",
      "author": "Chu",
      "year": "1996",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "2514",
      "DOI": "10.1126/science.286.5449.2514",
      "article-title": "Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation",
      "volume": "286",
      "author": "Brondello",
      "year": "1999",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0955-0674(99)00075-7_BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "2811",
      "DOI": "10.1101/gad.13.21.2811",
      "article-title": "A specific protein\u2013protein interaction accounts for the in vivo substrate selectivity of Ptp3 towards the Fus3 MAP kinase",
      "volume": "13",
      "author": "Zhan",
      "year": "1999",
      "journal-title": "Genes Dev"
    }
  ],
  "container-title": "Current Opinion in Cell Biology",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0955067499000757?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0955067499000757?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        4,
        16
      ]
    ],
    "date-time": "2023-04-16T18:55:53Z",
    "timestamp": 1681671353000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0955067499000757"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2000,
        4
      ]
    ]
  },
  "references-count": 49,
  "journal-issue": {
    "issue": "2",
    "published-print": {
      "date-parts": [
        [
          2000,
          4
        ]
      ]
    }
  },
  "alternative-id": [
    "S0955067499000757"
  ],
  "URL": "http://dx.doi.org/10.1016/S0955-0674(99)00075-7",
  "relation": {},
  "ISSN": [
    "0955-0674"
  ],
  "subject": [],
  "container-title-short": "Current Opinion in Cell Biology",
  "published": {
    "date-parts": [
      [
        2000,
        4
      ]
    ]
  }
}