10.1016/s0896-6273(03)00124-7
Crossref journal-article
Elsevier BV
Neuron (78)
Bibliography

Kamenetz, F., Tomita, T., Hsieh, H., Seabrook, G., Borchelt, D., Iwatsubo, T., Sisodia, S., & Malinow, R. (2003). APP Processing and Synaptic Function. Neuron, 37(6), 925–937.

Authors 8
  1. Flavio Kamenetz (first)
  2. Taisuke Tomita (additional)
  3. Helen Hsieh (additional)
  4. Guy Seabrook (additional)
  5. David Borchelt (additional)
  6. Takeshi Iwatsubo (additional)
  7. Sangram Sisodia (additional)
  8. Roberto Malinow (additional)
References 66 Referenced 1,278
  1. 10.1038/85525 / Nat. Med. / Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy by Bacskai (2001)
  2. 10.1016/S0896-6273(00)80230-5 / Neuron / Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo by Borchelt (1996)
  3. 10.1016/S0896-6273(00)80974-5 / Neuron / Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins by Borchelt (1997)
  4. 10.1038/85064 / Nat. Neurosci. / BACE1 is the major beta-secretase for generation of Abeta peptides by neurons by Cai (2001)
  5. 10.1126/science.1058783 / Science / A transcriptively active complex of app with fe65 and histone acetyltransferase tip60 by Cao (2001)
  6. 10.1038/35072500 / Nat. Rev. Neurosci. / Role of AMPA receptor endocytosis in synaptic plasticity by Carroll (2001)
  7. 10.1038/6374 / Nat. Neurosci. / Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice by Chapman (1999)
  8. 10.1038/360672a0 / Nature / Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production by Citron (1992)
  9. 10.1016/0896-6273(95)90323-2 / Neuron / Generation of amyloid beta protein from its precursor is sequence specific by Citron (1995)
  10. 10.1016/0197-4580(92)90060-B / Neurobiol. Aging / Beta-amyloid neurotoxicity by Cotman (1992)
  11. 10.1097/00001756-199710200-00006 / Neuroreport / Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments by Cullen (1997)
  12. 10.1016/S0896-6273(00)80458-4 / Neuron / Postsynaptic PKA controls quantal size and reveals a retrograde signal that regulates presynaptic transmitter release in Drosophila by Davis (1998)
  13. 10.1002/j.1460-2075.1995.tb00176.x / EMBO J. / Production of intracellular amyloid-containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence by De Strooper (1995)
  14. 10.1097/00002093-199803000-00002 / Alzheimer Dis. Assoc. Disord. / Benzodiazepines may have protective effects against Alzheimer disease by Fastbom (1998)
  15. 10.3109/13506120009146831 / Amyloid / An improved method of preparing the amyloid beta-protein for fibrillogenesis and neurotoxicity experiments by Fezoui (2000)
  16. 10.1523/JNEUROSCI.21-13-04691.2001 / J. Neurosci. / Age-related impairment of synaptic transmission but normal long-term potentiation in transgenic mice that over-express the human APP695SWE mutant form of amyloid precursor protein by Fitzjohn (2001)
  17. 10.1152/jn.2001.85.2.708 / J. Neurophysiol. / Blockade of long-term potentiation by beta-amyloid peptides in the CA1 region of the rat hippocampus in vivo by Freir (2001)
  18. 10.1038/379074a0 / Nature / Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein by Furukawa (1996)
  19. 10.1073/pnas.96.2.742 / Proc. Natl. Acad. Sci. USA / Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides by Greenfield (1999)
  20. 10.1523/JNEUROSCI.19-20-08876.1999 / J. Neurosci. / Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons by Hartley (1999)
  21. 10.1126/science.287.5461.2262 / Science / Driving AMPA receptors into synapses by LTP and CaMKII by Hayashi (2000)
  22. Howland, D.S., Trusko, S.P., Savage, M.J., Reaume, A.G., Lang, D.M., Hirsch, J.D., Maeda, N., Siman, R., Greenberg, B.D., Scott, R.W., et al. (1998). Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol. J. Biol. Chem. 273, 16576–15682. (10.1074/jbc.273.26.16576)
  23. 10.1073/pnas.96.6.3228 / Proc. Natl. Acad. Sci. USA / Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models by Hsia (1999)
  24. 10.1126/science.274.5284.99 / Science / Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice by Hsiao (1996)
  25. 10.1074/jbc.M007989200 / J. Biol.Chem. / Subcellular compartment and molecular subdomain of beta-amyloid precursor protein relevant to the Abeta 42-promoting effects of Alzheimer mutant presenilin 2 by Iwata (2001)
  26. 10.1111/j.1749-6632.1993.tb23043.x / Ann. N Y Acad. Sci. / The C-terminus of the beta protein is critical in amyloidogenesis by Jarrett (1993)
  27. 10.1016/0169-328X(91)90088-F / Brain Res. Mol. Brain Res. / Conservation of the sequence of the Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis by Johnstone (1991)
  28. 10.1038/414643a / Nature / Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP by Kamal (2001)
  29. 10.1523/JNEUROSCI.21-04-01327.2001 / J. Neurosci. / Use-dependent effects of amyloidogenic fragments of (beta)-amyloid precursor protein on synaptic plasticity in rat hippocampus in vivo by Kim (2001)
  30. 10.1073/pnas.95.11.6448 / Proc. Natl. Acad. Sci. USA / Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins by Lambert (1998)
  31. 10.1016/S0006-8993(99)01698-4 / Brain Res. / Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice by Larson (1999)
  32. 10.1038/35015085 / Nature / Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1 by Li (2000)
  33. 10.1038/85059 / Nat. Neurosci. / Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation by Luo (2001)
  34. {'key': '10.1016/S0896-6273(03)00124-7_BIB34', 'series-title': 'Introduction of Green Fluorescent Protein into Hippocampal Neurons through Viral Infection', 'author': 'Malinow', 'year': '1999'} / Introduction of Green Fluorescent Protein into Hippocampal Neurons through Viral Infection by Malinow (1999)
  35. 10.1016/S0959-4388(00)00099-4 / Curr. Opin. Neurobiol. / LTP mechanisms by Malinow (2000)
  36. 10.1038/35050116 / Nature / A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease by Morgan (2000)
  37. 10.1073/pnas.90.11.5191 / Proc. Natl. Acad. Sci. USA. / Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices by Nitsch (1993)
  38. 10.1074/jbc.274.27.18851 / J. Biol. Chem. / Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42 by Perez (1999)
  39. 10.1146/annurev.neuro.21.1.479 / Annu. Rev. Neurosci. / Mutant genes in familial Alzheimer's disease and transgenic models by Price (1998)
  40. Reisberg, B., Windscheif, U., Ferris, S.H., Hingorani, V.N., Stoeffler, A., and Moebius, H. (2000). Memantine in Moderately Severe to Severe Alzheimer's Disease: Results of a Placebo Controlled 6-Month Trial. In World Alzheimer's Congress (Washington D.C.). (10.1016/S0197-4580(00)83188-7)
  41. 10.1083/jcb.153.7.1403 / J. Cell Biol. / The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement by Sabo (2001)
  42. 10.1074/jbc.273.35.22351 / J. Biol. Chem. / X11 interaction with beta-amyloid precursor protein modulates its cellular stabilization and reduces amyloid beta-protein secretion by Sastre (1998)
  43. 10.1038/380446a0 / Nature / Role of intercellular interactions in heterosynaptic long-term depression by Scanziani (1996)
  44. 10.1016/S0958-1669(99)00006-3 / Curr. Opin. Biotechnol. / Alphavirus vectors for gene expression and vaccines by Schlesinger (1999)
  45. 10.1111/j.1749-6632.2000.tb05554.x / Ann. N Y Acad. Sci. / Toward a comprehensive theory for Alzheimer's disease. Hypothesis by Selkoe (2000)
  46. 10.1126/science.1074069 / Science. / Alzheimer's disease is a synaptic failure by Selkoe (2002)
  47. 10.1038/359325a0 / Nature / Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids by Seubert (1992)
  48. 10.1126/science.284.5421.1811 / Science / Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation by Shi (1999)
  49. 10.1523/JNEUROSCI.13-07-03136.1993 / J. Neurosci. / Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system by Sisodia (1993)
  50. 10.1038/sj.cdd.4400391 / Cell Death Differ. / Hypersensitivity to seizures in beta-amyloid precursor protein deficient mice by Steinbach (1998)
  51. 10.1523/JNEUROSCI.21-15-05703.2001 / J. Neurosci. / Generation of aggregated beta-amyloid in the rat hippocampus impairs synaptic transmission and plasticity and causes memory deficits by Stephan (2001)
  52. 10.1016/0165-0270(91)90128-M / J. Neurosci. Methods / A simple method for organotypic cultures of nervous tissue by Stoppini (1991)
  53. 10.1126/science.8191290 / Science / An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants by Suzuki (1994)
  54. 10.1073/pnas.94.5.2025 / Proc. Natl. Acad. Sci. USA / The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue by Tomita (1997)
  55. 10.1038/36103 / Nature / Activity-dependent scaling of quantal amplitude in neocortical neurons by Turrigiano (1998)
  56. 10.1074/jbc.274.36.25945 / J. Biol. Chem. / Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates by Walsh (1999)
  57. 10.1038/416535a / Nature / Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo by Walsh (2002)
  58. 10.1038/ng0993-95 / Nat. Genet. / Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor by Wasco (1993)
  59. 10.1523/JNEUROSCI.22-05-01858.2002 / J. Neurosci. / The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease by Westerman (2002)
  60. 10.1002/(SICI)1099-1166(199902)14:2<135::AID-GPS906>3.0.CO;2-0 / Int. J. Geriatr. Psychiatry / Memantine in severe dementia by Winblad (1999)
  61. 10.1126/science.2474201 / Science / Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease by Yankner (1989)
  62. 10.1126/science.2218531 / Science / Neurotrophic and neurotoxic effects of amyloid beta protein by Yankner (1990)
  63. 10.1038/35024009 / Nature / Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing by Yu (2000)
  64. 10.1111/j.1749-6632.1996.tb34456.x / Ann. N Y Acad. Sci. / Mice deficient for the amyloid precursor protein gene by Zheng (1996)
  65. 10.1038/80614 / Nat. Neurosci. / Postnatal synaptic potentiation by Zhu (2000)
  66. 10.1016/S0959-4388(00)00135-5 / Curr. Opin. Neurobiol. / Neurobiology of disease by Zoghbi (2000)
Dates
Type When
Created 21 years, 4 months ago (April 21, 2004, 3:12 a.m.)
Deposited 5 years, 5 months ago (April 1, 2020, 11:57 a.m.)
Indexed 2 days, 15 hours ago (Sept. 3, 2025, 6:56 a.m.)
Issued 22 years, 6 months ago (March 1, 2003)
Published 22 years, 6 months ago (March 1, 2003)
Published Print 22 years, 6 months ago (March 1, 2003)
Funders 0

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@article{Kamenetz_2003, title={APP Processing and Synaptic Function}, volume={37}, ISSN={0896-6273}, url={http://dx.doi.org/10.1016/s0896-6273(03)00124-7}, DOI={10.1016/s0896-6273(03)00124-7}, number={6}, journal={Neuron}, publisher={Elsevier BV}, author={Kamenetz, Flavio and Tomita, Taisuke and Hsieh, Helen and Seabrook, Guy and Borchelt, David and Iwatsubo, Takeshi and Sisodia, Sangram and Malinow, Roberto}, year={2003}, month=mar, pages={925–937} }