DOI: 10.1016/s0896-6273(00)80026-4. Signaling from Synapse to Nucleus: Postsynaptic CREB Phosphorylation during Multiple Forms of Hippocampal Synaptic Plasticity

Signaling from Synapse to Nucleus: Postsynaptic CREB Phosphorylation during Multiple Forms of Hippocampal Synaptic Plasticity

10.1016/s0896-6273(00)80026-4

Crossref journal-article

Elsevier BV

Neuron (78)

Bibliography

Deisseroth, K., Bito, H., & Tsien, R. W. (1996). Signaling from Synapse to Nucleus: Postsynaptic CREB Phosphorylation during Multiple Forms of Hippocampal Synaptic Plasticity. Neuron, 16(1), 89â101.

Authors 3

Karl Deisseroth (first)
Haruhiko Bito (additional)
Richard W Tsien (additional)

References 83 Referenced 595

10.1073/pnas.91.21.10049 / Proc. Natl. Acad. Sci. USA / Immediate early gene expression associated with the persistence of heterosynaptic long-term depression in the hippocampus by Abraham (1994)
10.1523/JNEUROSCI.11-06-01496.1991 / J. Neurosci / Alien intracellular calcium chelators attenuate neurotransmitter release at the squid giant synapse by Adler (1991)
10.1016/0092-8674(94)90386-7 / Cell / C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia by Alberini (1994)
10.1038/376074a0 / Nature / Activity-dependent long-term enhancement of transmitter release by presynaptic 3′,5′-cyclic GMP in cultured hippocampal neurons by Arancio (1995)
10.1016/0896-6273(95)90056-X / Neuron / Mechanism for a sliding synaptic modification threshold by Bear (1995)
10.1038/346724a0 / Nature / Presynaptic mechanism for long-term potentiation in the hippocampus by Bekkers (1990)
10.1038/361315a0 / Nature / Inositol trisphosphate and calcium signalling by Berridge (1993)
10.1126/science.7909958 / Science / Postsynaptic induction and presynaptic expression of hippocampal long-term depression by Bolshakov (1994)
10.1016/0092-8674(94)90400-6 / Cell / Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein by Bourtchuladze (1994)
10.1016/S0959-437X(05)80274-6 / Curr. Opin. Genet. Dev / The CREB family of transcription activators by Brindle (1992)
10.1016/0306-4522(83)90145-8 / Neurosci / Distribution and subcellular localization of calmodulin in adult and developing brain tissue by Caceres (1983)
10.1016/S0021-9258(17)32700-X / J. Biol. Chem / TypeVIII adenylyl cyclase. A Ca2+/calmodulin-stimulated enzyme expressed in discrete regions of rat brain by Cali (1994)
10.1016/0955-0674(93)90115-7 / Curr. Opin. Cell Biol / The regulatory diversity of the mammalian adenylyl cyclases by Choi (1993)
10.1038/365855a0 / Nature / Phosphorylated CREB binds specifically to the nuclear protein CBP by Chrivia (1993)
10.1038/340474a0 / Nature / Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation by Cole (1989)
10.1038/345718a0 / Nature / Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation by Dash (1990)
10.1073/pnas.88.11.5061 / Proc. Natl. Acad. Sci. USA / cAMP response element-binding protein is activated by Ca2+-calmodulin- as well as cAMP-dependent protein kinase by Dash (1991)
10.1037/0033-2909.96.3.518 / Psychol. Bull / Protein synthesis and memory by Davis (1984)
10.1016/S0960-9822(95)00262-4 / Curr. Biol / A molecular mechanism for metaplasticity by Deisseroth (1995)
10.1073/pnas.89.10.4363 / Proc. Natl. Acad. Sci USA / Homosynaptic long-term depression in area CA1 of hippocampus and the effects of NMDA receptor blockade by Dudek (1992)
10.1113/jphysiol.1993.sp019967 / J. Physiol / Potassium currents operated by thyrotropin-releasing hormone in dissociated CA1 pyramidal neurones of rat hippocampus by Ebihara (1993)
10.1016/S0021-9258(17)40710-1 / J. Biol. Chem / Characterization of Ca2+-calmodulin dependent kinase IV. Role in transcriptional regulation by Enslen (1994)
10.1016/S0021-9258(18)31619-3 / J. Biol. Chem / A secondary phosphorylation of CREB341 at Ser-129 is required for the cAMP-mediated control of gene expression. A role for glycogen synthetase kinase-3 in the control of gene expression by Fiol (1994)
10.1016/0092-8674(94)90394-8 / Cell / CREB by Frank (1994)
10.1126/science.8389057 / Science / Effects of cAMP simulate a late stage of LTP in hippocampal neurons by Frey (1993)
10.1126/science.7907431 / Science / Requirement for BDNF in activity-dependent survival of cortical neurons by Ghosh (1994)
10.1126/science.8097062 / Science / Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock by Ginty (1993)
10.1016/S0896-6273(00)80027-6 / Neuron, this issue / Long-term depression properties in a simple system by Goda (1996)
10.1016/0092-8674(89)90013-5 / Cell / Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at Ser-133 by Gonzalez (1989)
{'key': '10.1016/S0896-6273(00)80026-4_BIB30', 'first-page': '4852', 'article-title': 'Coupling of hormonal stimulation and transcription via the cyclic AMP responsive factor CREB is rate-limited by nuclear entry of protein kinase A', 'volume': '13', 'author': 'Hagiwara', 'year': '1994', 'journal-title': 'Mol. Cell. Biol'} / Mol. Cell. Biol / Coupling of hormonal stimulation and transcription via the cyclic AMP responsive factor CREB is rate-limited by nuclear entry of protein kinase A by Hagiwara (1994)
10.1016/0896-6273(94)90467-7 / Neuron / Depolarization-transcription signals in skeletal muscle use calcium flux through L channels but bypass the sarcoplasmic reticulum by Huang (1994)
10.1016/0092-8674(94)90401-4 / Cell / cAMP contributes to mossy fiber LTP by initiating both a covalently modified early phase and macromolecular synthesis-dependent late phase by Huang (1994)
10.1016/0092-8674(92)90162-6 / Cell / The regulation of transcription by phosphorylation by Hunter (1992)
10.1016/0896-6273(92)90159-B / Neuron / Submicroscopic Ca2+ diffusion mediates inhibitory coupling between individual Ca2+ channels by Imredy (1992)
10.1113/jphysiol.1992.sp019360 / J. Physiol / Interactions between Ca2+-mobilizing mechanisms in cultured rat cerebellar granule cells by Irving (1992)
10.1016/0896-6273(93)90331-K / Neuron / Activation of cAMP-responsive genes by stimuli that produce long-term facilitation in Aplysia sensory neurons by Kaang (1993)
10.1016/S0021-9258(17)32442-0 / J. Biol. Chem / Signal transduction and gene regulation by Lalli (1994)
10.1016/0167-4781(93)90191-F / Biochim. Biophys. Acta / Transcriptional regulation of CREB and its relatives by Lee (1993)
{'key': '10.1016/S0896-6273(00)80026-4_BIB39', 'first-page': '43', 'article-title': 'What does the nucleus know about memories?', 'volume': '7', 'author': 'Lisman', 'year': '1995', 'journal-title': 'J. NIH Res'} / J. NIH Res / What does the nucleus know about memories? by Lisman (1995)
10.1038/305719a0 / Nature / Intracellular injections of EGTA block induction of hippocampal long-term potentiation by Lynch (1983)
10.1016/0896-6273(92)90191-F / Neuron / Stimulus-induced coordinate changes in mRNA abundance in single postsynaptic hippocampal neurons by Mackler (1992)
10.1016/0092-8674(94)90517-7 / Cell / Synaptic plasticity in the hippocampus by Malenka (1994)
10.1016/0896-6273(92)90227-5 / Neuron / Temporal limits on the rise in postsynaptic calcium required for the induction of long-term potentiation by Malenka (1992)
10.1038/357134a0 / Nature / Glutamate-induced long-term potentiation of frequency of miniature synaptic currents in cultured hippocampal neurons by Malgaroli (1992)
10.1126/science.2549638 / Science / Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP by Malinow (1989)
{'key': '10.1016/S0896-6273(00)80026-4_BIB45', 'first-page': '6107', 'article-title': 'Calcium/calmodulin dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression', 'volume': '14', 'author': 'Matthews', 'year': '1994', 'journal-title': 'Mol. Cell. Biol'} / Mol. Cell. Biol / Calcium/calmodulin dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression by Matthews (1994)
10.1016/0959-4388(95)80019-0 / Curr. Opin. Neurobiol / Transgenic approach to cognition by Mayford (1995)
10.1016/0092-8674(95)90009-8 / Cell / CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP by Mayford (1995)
10.1016/0896-6273(93)90167-P / Neuron / Transcriptional response to cAMP in brain by Mellstrom (1993)
10.1016/0166-2236(89)90096-9 / Trends Neurosci / Stimulus-transcription coupling in neurons by Morgan (1989)
10.1016/S0021-9258(19)74340-3 / J. Biol. Chem / The transcription of a voltage-gated potassium channel is regulated by cAMP in a cell type–specific manner by Mori (1993)
10.1016/0896-6273(92)90248-C / Neuron / Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus by Mulkey (1992)
Neher, E. (1986). Concentration profiles of intracellular calcium in the presence of a diffusible chelator. In Calcium Electrogenesis and Neuronal Functioning, Experimental Brain Research Series, Vol. 14, U. Heinemann et al., eds. (Berlin: Springer-Verlag), pp. 80–96. (10.1007/978-3-642-70744-5_8)
10.1073/pnas.92.5.1659 / Proc. Natl. Acad. Sci. USA / Functional identification of the promoter for the gene encoding the α subunit of the calcium/calmodulin-dependent protein kinase II by Olson (1995)
10.1126/science.7997883 / Science / Potentiated transmission and prevention of further LTP by increased CaMKII activity in postsynaptic hippocampal slice neurons by Pettit (1994)
10.1038/363074a0 / Nature / Spatial calcium buffering in saccular hair cells by Roberts (1993)
10.1523/JNEUROSCI.10-11-03664.1990 / J. Neurosci / Colocalization of ion channels involved in frequency selectivity and synaptic transmission at presynaptic active zones of hair cells by Roberts (1990)
{'key': '10.1016/S0896-6273(00)80026-4_BIB57', 'first-page': '867', 'article-title': '5′-upstream sequence and the genomic structure of the human primary responsive gene EGR-1/TIS8', 'volume': '6', 'author': 'Sakamoto', 'year': '1991', 'journal-title': 'Oncogene'} / Oncogene / 5′-upstream sequence and the genomic structure of the human primary responsive gene EGR-1/TIS8 by Sakamoto (1991)
10.1101/gad.2.12a.1529 / Genes Dev / Induction of proto-oncogene fos transcription through adenylate cyclase pathway by Sassone-Corsi (1988)
10.1016/S0021-9258(18)77206-2 / J. Biol. Chem / 5′-flanking region of the synapsin I gene by Sauerwald (1990)
10.1016/0896-6273(90)90106-P / Neuron / The regulation and function of c-fos and other immediate-early genes in the nervous system by Sheng (1990)
10.1126/science.1646483 / Science / CREB by Sheng (1991)
10.1113/jphysiol.1980.sp013138 / J. Physiol / Calcium-activated transient outward current in calf cardiac Purkinje fibres by Siegelbaum (1980)
10.1016/0959-4388(94)90104-X / Curr. Opin. Neurobiol / Plastic genes are in! by Silva (1994)
10.1126/science.1378648 / Science / Deficient hippocampal long-term potentiation in α-calcium-calmodulin kinase II mutant mice by Silva (1992)
10.1016/0143-4160(92)90046-U / Cell Calcium / Buffering of calcium in the vicinity of a channel pore by Stern (1992)
10.1016/0896-6273(94)90244-5 / Neuron / CREB and memory consolidation by Stevens (1994)
10.1038/371704a0 / Nature / Changes in reliability of synaptic function as a mechanism for plasticity by Stevens (1994)
10.1016/0896-6273(95)90223-6 / Neuron / Facilitation and depression at single central synapses by Stevens (1995)
10.1016/S0960-9822(00)00153-6 / Curr. Biol / The role of calcium-calmodulin kinase II in three forms of synaptic plasticity by Stevens (1994)
10.1101/gad.8.21.2527 / Genes Dev / Differential activation of CREB by Ca2+-calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity by Sun (1994)
10.1016/0896-6273(91)90337-Y / Neuron / Role of residual calcium in synaptic depression and posttetanic potentiation by Swandulla (1991)
10.1016/0896-6273(94)90040-X / Neuron / Spatial and temporal changes in signal transduction pathways during LTP by Thomas (1994)
10.1074/jbc.270.9.4224 / J. Biol. Chem / L-type voltage-sensitive Ca2+-channel activation regulates c-fos transcription at multiple levels by Thompson (1995)
10.1021/bi00552a018 / Biochemistry / New calcium indicators and buffers with high selectivity against magnesium and protons by Tsien (1980)
10.1016/0092-8674(94)90398-0 / Cell / Genetic dissection of consolidated memory in Drosophila by Tully (1994)
10.1126/science.8351520 / Science / Dynamics of the hippocampal ensemble code for space by Wilson (1993)
10.1016/0896-6273(90)90118-Y / Neuron / Differential expression of immediate early genes in the hippocampus and spinal cord by Wisden (1990)
10.1523/JNEUROSCI.13-11-04776.1993 / J. Neurosci / Transcription factors in the hippocampus by Worley (1993)
10.1016/0896-6273(94)90031-0 / Neuron / A role for protein kinases and phosphatases in the Ca2+-induced enhancement of hippocampal AMPA receptor–mediated synaptic responses by Wyllie (1994)
10.1016/0896-6273(91)90251-T / Neuron / Distribution of mRNA for the calmodulin-sensitive adenylate cyclase in rat brain by Xia (1991)
10.1016/0092-8674(94)90399-9 / Cell / Induction of a dominant-negative CREB transgene blocks long-term memory in Drosophila by Yin (1994)
10.1016/0092-8674(95)90375-5 / Cell / CREB as a memory modulator by Yin (1995)

Dates

Type	When
Created	21 years, 4 months ago (April 13, 2004, 5:31 a.m.)
Deposited	8 months, 1 week ago (Dec. 15, 2024, 3:45 p.m.)
Indexed	3 weeks, 4 days ago (July 30, 2025, 11:14 a.m.)
Issued	29 years, 7 months ago (Jan. 1, 1996)
Published	29 years, 7 months ago (Jan. 1, 1996)
Published Print	29 years, 7 months ago (Jan. 1, 1996)

Funders 0

None

BibTeX

@article{Deisseroth_1996, title={Signaling from Synapse to Nucleus: Postsynaptic CREB Phosphorylation during Multiple Forms of Hippocampal Synaptic Plasticity}, volume={16}, ISSN={0896-6273}, url={http://dx.doi.org/10.1016/s0896-6273(00)80026-4}, DOI={10.1016/s0896-6273(00)80026-4}, number={1}, journal={Neuron}, publisher={Elsevier BV}, author={Deisseroth, Karl and Bito, Haruhiko and Tsien, Richard W}, year={1996}, month=jan, pages={89–101} }

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      "volume": "376",
      "author": "Arancio",
      "year": "1995",
      "journal-title": "Nature"
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      "doi-asserted-by": "crossref",
      "first-page": "1334",
      "DOI": "10.1016/S0960-9822(95)00262-4",
      "article-title": "A molecular mechanism for metaplasticity",
      "volume": "5",
      "author": "Deisseroth",
      "year": "1995",
      "journal-title": "Curr. Biol"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB20",
      "doi-asserted-by": "crossref",
      "first-page": "4363",
      "DOI": "10.1073/pnas.89.10.4363",
      "article-title": "Homosynaptic long-term depression in area CA1 of hippocampus and the effects of NMDA receptor blockade",
      "volume": "89",
      "author": "Dudek",
      "year": "1992",
      "journal-title": "Proc. Natl. Acad. Sci USA"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "689",
      "DOI": "10.1113/jphysiol.1993.sp019967",
      "article-title": "Potassium currents operated by thyrotropin-releasing hormone in dissociated CA1 pyramidal neurones of rat hippocampus",
      "volume": "472",
      "author": "Ebihara",
      "year": "1993",
      "journal-title": "J. Physiol"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "15520",
      "DOI": "10.1016/S0021-9258(17)40710-1",
      "article-title": "Characterization of Ca2+-calmodulin dependent kinase IV. Role in transcriptional regulation",
      "volume": "269",
      "author": "Enslen",
      "year": "1994",
      "journal-title": "J. Biol. Chem"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "32187",
      "DOI": "10.1016/S0021-9258(18)31619-3",
      "article-title": "A secondary phosphorylation of CREB341 at Ser-129 is required for the cAMP-mediated control of gene expression. A role for glycogen synthetase kinase-3 in the control of gene expression",
      "volume": "269",
      "author": "Fiol",
      "year": "1994",
      "journal-title": "J. Biol. Chem"
    },
    {
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      "first-page": "5",
      "DOI": "10.1016/0092-8674(94)90394-8",
      "article-title": "CREB",
      "volume": "79",
      "author": "Frank",
      "year": "1994",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "1661",
      "DOI": "10.1126/science.8389057",
      "article-title": "Effects of cAMP simulate a late stage of LTP in hippocampal neurons",
      "volume": "260",
      "author": "Frey",
      "year": "1993",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "1618",
      "DOI": "10.1126/science.7907431",
      "article-title": "Requirement for BDNF in activity-dependent survival of cortical neurons",
      "volume": "263",
      "author": "Ghosh",
      "year": "1994",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "238",
      "DOI": "10.1126/science.8097062",
      "article-title": "Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock",
      "volume": "260",
      "author": "Ginty",
      "year": "1993",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB28",
      "doi-asserted-by": "crossref",
      "DOI": "10.1016/S0896-6273(00)80027-6",
      "article-title": "Long-term depression properties in a simple system",
      "author": "Goda",
      "year": "1996",
      "journal-title": "Neuron, this issue"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "675",
      "DOI": "10.1016/0092-8674(89)90013-5",
      "article-title": "Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at Ser-133",
      "volume": "59",
      "author": "Gonzalez",
      "year": "1989",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB30",
      "first-page": "4852",
      "article-title": "Coupling of hormonal stimulation and transcription via the cyclic AMP responsive factor CREB is rate-limited by nuclear entry of protein kinase A",
      "volume": "13",
      "author": "Hagiwara",
      "year": "1994",
      "journal-title": "Mol. Cell. Biol"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "167",
      "DOI": "10.1016/0896-6273(94)90467-7",
      "article-title": "Depolarization-transcription signals in skeletal muscle use calcium flux through L channels but bypass the sarcoplasmic reticulum",
      "volume": "13",
      "author": "Huang",
      "year": "1994",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "69",
      "DOI": "10.1016/0092-8674(94)90401-4",
      "article-title": "cAMP contributes to mossy fiber LTP by initiating both a covalently modified early phase and macromolecular synthesis-dependent late phase",
      "volume": "79",
      "author": "Huang",
      "year": "1994",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "375",
      "DOI": "10.1016/0092-8674(92)90162-6",
      "article-title": "The regulation of transcription by phosphorylation",
      "volume": "70",
      "author": "Hunter",
      "year": "1992",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "197",
      "DOI": "10.1016/0896-6273(92)90159-B",
      "article-title": "Submicroscopic Ca2+ diffusion mediates inhibitory coupling between individual Ca2+ channels",
      "volume": "9",
      "author": "Imredy",
      "year": "1992",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "667",
      "DOI": "10.1113/jphysiol.1992.sp019360",
      "article-title": "Interactions between Ca2+-mobilizing mechanisms in cultured rat cerebellar granule cells",
      "volume": "456",
      "author": "Irving",
      "year": "1992",
      "journal-title": "J. Physiol"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "427",
      "DOI": "10.1016/0896-6273(93)90331-K",
      "article-title": "Activation of cAMP-responsive genes by stimuli that produce long-term facilitation in Aplysia sensory neurons",
      "volume": "10",
      "author": "Kaang",
      "year": "1993",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "17359",
      "DOI": "10.1016/S0021-9258(17)32442-0",
      "article-title": "Signal transduction and gene regulation",
      "volume": "269",
      "author": "Lalli",
      "year": "1994",
      "journal-title": "J. Biol. Chem"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "221",
      "DOI": "10.1016/0167-4781(93)90191-F",
      "article-title": "Transcriptional regulation of CREB and its relatives",
      "volume": "1174",
      "author": "Lee",
      "year": "1993",
      "journal-title": "Biochim. Biophys. Acta"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB39",
      "first-page": "43",
      "article-title": "What does the nucleus know about memories?",
      "volume": "7",
      "author": "Lisman",
      "year": "1995",
      "journal-title": "J. NIH Res"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "719",
      "DOI": "10.1038/305719a0",
      "article-title": "Intracellular injections of EGTA block induction of hippocampal long-term potentiation",
      "volume": "305",
      "author": "Lynch",
      "year": "1983",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "539",
      "DOI": "10.1016/0896-6273(92)90191-F",
      "article-title": "Stimulus-induced coordinate changes in mRNA abundance in single postsynaptic hippocampal neurons",
      "volume": "9",
      "author": "Mackler",
      "year": "1992",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB001",
      "doi-asserted-by": "crossref",
      "first-page": "535",
      "DOI": "10.1016/0092-8674(94)90517-7",
      "article-title": "Synaptic plasticity in the hippocampus",
      "volume": "78",
      "author": "Malenka",
      "year": "1994",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "121",
      "DOI": "10.1016/0896-6273(92)90227-5",
      "article-title": "Temporal limits on the rise in postsynaptic calcium required for the induction of long-term potentiation",
      "volume": "9",
      "author": "Malenka",
      "year": "1992",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "134",
      "DOI": "10.1038/357134a0",
      "article-title": "Glutamate-induced long-term potentiation of frequency of miniature synaptic currents in cultured hippocampal neurons",
      "volume": "357",
      "author": "Malgaroli",
      "year": "1992",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "862",
      "DOI": "10.1126/science.2549638",
      "article-title": "Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP",
      "volume": "245",
      "author": "Malinow",
      "year": "1989",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB45",
      "first-page": "6107",
      "article-title": "Calcium/calmodulin dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression",
      "volume": "14",
      "author": "Matthews",
      "year": "1994",
      "journal-title": "Mol. Cell. Biol"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "141",
      "DOI": "10.1016/0959-4388(95)80019-0",
      "article-title": "Transgenic approach to cognition",
      "volume": "5",
      "author": "Mayford",
      "year": "1995",
      "journal-title": "Curr. Opin. Neurobiol"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "891",
      "DOI": "10.1016/0092-8674(95)90009-8",
      "article-title": "CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP",
      "volume": "81",
      "author": "Mayford",
      "year": "1995",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "655",
      "DOI": "10.1016/0896-6273(93)90167-P",
      "article-title": "Transcriptional response to cAMP in brain",
      "volume": "10",
      "author": "Mellstrom",
      "year": "1993",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "459",
      "DOI": "10.1016/0166-2236(89)90096-9",
      "article-title": "Stimulus-transcription coupling in neurons",
      "volume": "12",
      "author": "Morgan",
      "year": "1989",
      "journal-title": "Trends Neurosci"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB50",
      "doi-asserted-by": "crossref",
      "first-page": "26482",
      "DOI": "10.1016/S0021-9258(19)74340-3",
      "article-title": "The transcription of a voltage-gated potassium channel is regulated by cAMP in a cell type\u2013specific manner",
      "volume": "268",
      "author": "Mori",
      "year": "1993",
      "journal-title": "J. Biol. Chem"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB51",
      "doi-asserted-by": "crossref",
      "first-page": "967",
      "DOI": "10.1016/0896-6273(92)90248-C",
      "article-title": "Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus",
      "volume": "9",
      "author": "Mulkey",
      "year": "1992",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB52",
      "doi-asserted-by": "crossref",
      "unstructured": "Neher, E. (1986). Concentration profiles of intracellular calcium in the presence of a diffusible chelator. In Calcium Electrogenesis and Neuronal Functioning, Experimental Brain Research Series, Vol. 14, U. Heinemann et al., eds. (Berlin: Springer-Verlag), pp. 80\u201396.",
      "DOI": "10.1007/978-3-642-70744-5_8"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB53",
      "doi-asserted-by": "crossref",
      "first-page": "1659",
      "DOI": "10.1073/pnas.92.5.1659",
      "article-title": "Functional identification of the promoter for the gene encoding the \u03b1 subunit of the calcium/calmodulin-dependent protein kinase II",
      "volume": "92",
      "author": "Olson",
      "year": "1995",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB54",
      "doi-asserted-by": "crossref",
      "first-page": "1081",
      "DOI": "10.1126/science.7997883",
      "article-title": "Potentiated transmission and prevention of further LTP by increased CaMKII activity in postsynaptic hippocampal slice neurons",
      "volume": "266",
      "author": "Pettit",
      "year": "1994",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB55",
      "doi-asserted-by": "crossref",
      "first-page": "74",
      "DOI": "10.1038/363074a0",
      "article-title": "Spatial calcium buffering in saccular hair cells",
      "volume": "363",
      "author": "Roberts",
      "year": "1993",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB56",
      "doi-asserted-by": "crossref",
      "first-page": "3664",
      "DOI": "10.1523/JNEUROSCI.10-11-03664.1990",
      "article-title": "Colocalization of ion channels involved in frequency selectivity and synaptic transmission at presynaptic active zones of hair cells",
      "volume": "10",
      "author": "Roberts",
      "year": "1990",
      "journal-title": "J. Neurosci"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB57",
      "first-page": "867",
      "article-title": "5\u2032-upstream sequence and the genomic structure of the human primary responsive gene EGR-1/TIS8",
      "volume": "6",
      "author": "Sakamoto",
      "year": "1991",
      "journal-title": "Oncogene"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB58",
      "doi-asserted-by": "crossref",
      "first-page": "1529",
      "DOI": "10.1101/gad.2.12a.1529",
      "article-title": "Induction of proto-oncogene fos transcription through adenylate cyclase pathway",
      "volume": "2",
      "author": "Sassone-Corsi",
      "year": "1988",
      "journal-title": "Genes Dev"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB59",
      "doi-asserted-by": "crossref",
      "first-page": "14932",
      "DOI": "10.1016/S0021-9258(18)77206-2",
      "article-title": "5\u2032-flanking region of the synapsin I gene",
      "volume": "265",
      "author": "Sauerwald",
      "year": "1990",
      "journal-title": "J. Biol. Chem"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB60",
      "doi-asserted-by": "crossref",
      "first-page": "477",
      "DOI": "10.1016/0896-6273(90)90106-P",
      "article-title": "The regulation and function of c-fos and other immediate-early genes in the nervous system",
      "volume": "4",
      "author": "Sheng",
      "year": "1990",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB61",
      "doi-asserted-by": "crossref",
      "first-page": "1427",
      "DOI": "10.1126/science.1646483",
      "article-title": "CREB",
      "volume": "252",
      "author": "Sheng",
      "year": "1991",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB62",
      "doi-asserted-by": "crossref",
      "first-page": "485",
      "DOI": "10.1113/jphysiol.1980.sp013138",
      "article-title": "Calcium-activated transient outward current in calf cardiac Purkinje fibres",
      "volume": "299",
      "author": "Siegelbaum",
      "year": "1980",
      "journal-title": "J. Physiol"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB63",
      "doi-asserted-by": "crossref",
      "first-page": "413",
      "DOI": "10.1016/0959-4388(94)90104-X",
      "article-title": "Plastic genes are in!",
      "volume": "4",
      "author": "Silva",
      "year": "1994",
      "journal-title": "Curr. Opin. Neurobiol"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB64",
      "doi-asserted-by": "crossref",
      "first-page": "201",
      "DOI": "10.1126/science.1378648",
      "article-title": "Deficient hippocampal long-term potentiation in \u03b1-calcium-calmodulin kinase II mutant mice",
      "volume": "257",
      "author": "Silva",
      "year": "1992",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB65",
      "doi-asserted-by": "crossref",
      "first-page": "183",
      "DOI": "10.1016/0143-4160(92)90046-U",
      "article-title": "Buffering of calcium in the vicinity of a channel pore",
      "volume": "13",
      "author": "Stern",
      "year": "1992",
      "journal-title": "Cell Calcium"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB66",
      "doi-asserted-by": "crossref",
      "first-page": "769",
      "DOI": "10.1016/0896-6273(94)90244-5",
      "article-title": "CREB and memory consolidation",
      "volume": "13",
      "author": "Stevens",
      "year": "1994",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB67",
      "doi-asserted-by": "crossref",
      "first-page": "704",
      "DOI": "10.1038/371704a0",
      "article-title": "Changes in reliability of synaptic function as a mechanism for plasticity",
      "volume": "371",
      "author": "Stevens",
      "year": "1994",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB68",
      "doi-asserted-by": "crossref",
      "first-page": "795",
      "DOI": "10.1016/0896-6273(95)90223-6",
      "article-title": "Facilitation and depression at single central synapses",
      "volume": "14",
      "author": "Stevens",
      "year": "1995",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB69",
      "doi-asserted-by": "crossref",
      "first-page": "687",
      "DOI": "10.1016/S0960-9822(00)00153-6",
      "article-title": "The role of calcium-calmodulin kinase II in three forms of synaptic plasticity",
      "volume": "4",
      "author": "Stevens",
      "year": "1994",
      "journal-title": "Curr. Biol"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB70",
      "doi-asserted-by": "crossref",
      "first-page": "2527",
      "DOI": "10.1101/gad.8.21.2527",
      "article-title": "Differential activation of CREB by Ca2+-calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity",
      "volume": "8",
      "author": "Sun",
      "year": "1994",
      "journal-title": "Genes Dev"
    },
    {
      "key": "10.1016/S0896-6273(00)80026-4_BIB71",
      "doi-asserted-by": "crossref",
      "first-page": "915",
      "DOI": "10.1016/0896-6273(91)90337-Y",
      "article-title": "Role of residual calcium in synaptic depression and posttetanic potentiation",
      "volume": "7",
      "author": "Swandulla",
      "year": "1991",
      "journal-title": "Neuron"
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