DOI: 10.1016/s0896-6273(00)00146-x. A LIS1/NUDEL/Cytoplasmic Dynein Heavy Chain Complex in the Developing and Adult Nervous System

A LIS1/NUDEL/Cytoplasmic Dynein Heavy Chain Complex in the Developing and Adult Nervous System

10.1016/s0896-6273(00)00146-x

Crossref journal-article

Elsevier BV

Neuron (78)

Bibliography

Sasaki, S., Shionoya, A., Ishida, M., Gambello, M. J., Yingling, J., Wynshaw-Boris, A., & Hirotsune, S. (2000). A LIS1/NUDEL/Cytoplasmic Dynein Heavy Chain Complex in the Developing and Adult Nervous System. Neuron, 28(3), 681â696.

Authors 7

Shinji Sasaki (first)
Aki Shionoya (additional)
Michiyo Ishida (additional)
Michael J. Gambello (additional)
Jessica Yingling (additional)
Anthony Wynshaw-Boris (additional)
Shinji Hirotsune (additional)

References 52 Referenced 430

10.1016/S0896-6273(00)80675-3 / Neuron / Microtubules and neuronal polarity by Baas (1999)
10.1016/S0896-6273(01)80044-1 / Neuron / Mice lacking p35, a neuronal specific activator of cdk5 display cortical lamination defects, seizure, and adult lethality by Chae (1997)
10.1091/mbc.8.9.1735 / Mol. Biol. Cell / Deletion of nudC, a nuclear migration gene of Aspergillus nidulans, causes morphological and cell wall abnormalities and is lethal by Chiu (1997)
10.1016/S0925-4773(97)00085-3 / Mech. Dev. / Characterization of DnudC, the Drosophila homologue of an Aspergillus gene that functions in nuclear motility by Cunniff (1997)
10.1038/374719a0 / Nature / A protein related to extracellular matrix proteins deleted in the mice mutant reeler by D'Arcangelo (1995)
10.1001/jama.1993.03510230076039 / J. Am. Med. Assoc. / Lissencephaly. A human brain malformation associated with deletion of the LIS1 gene located at chromosome 17p13 by Dobyns (1993)
10.1083/jcb.150.3.681 / J. Cell Biol. / The LIS1-related NUDF protein of Aspergillus nidulans interacts with the coiled-coil domain of the NUDE/RO11 protein by Efimov (2000)
10.1038/35041020 / Nat. Cell Biol. / A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function by Faulkner (2000)
10.1016/S0896-6273(00)00145-8 / Neuron, this issue / LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome by Feng (2000)
10.1016/0165-0173(84)90013-4 / Brain Res. Rev. / Events governing organization of postmigratory neurons by Goffinet (1984)
10.1016/S0896-6273(00)81244-1 / Neuron / Characterization of KIFC2, a neuronal kinesin superfamily member in mouse by Hanlon (1997)
10.1038/ng0595-77 / Nat. Genet. / The reeler gene encodes a protein with EGF-like motif expressed by pioneer neurons by Hirotsune (1995)
10.1038/1221 / Nat. Genet. / Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality by Hirotsune (1998)
10.1038/39607 / Nature / Neuronal position in the developing brain is regulated by mouse disabled-1 by Howell (1997)
10.1101/gad.13.6.643 / Genes Dev. / Reelin-induced tyrosine phosphorylation of disabled 1 during neuronal positioning by Howell (1999)
10.1038/35012636 / Nature / Neurotoxicity induces cleavage of p35 to p25 by calpain by Lee (2000)
10.1242/dev.126.20.4477 / Development / Lis1, the Drosophila homologue of a human lissencephaly disease gene, is required for germline cell division and oocyte differentiation by Liu (1999)
10.1038/35041011 / Nat. Cell Biol. / Drosophila Lis1 is required for neuroblast proliferation, dendritic elaboration and axonal transport by Liu (2000)
10.1093/hmg/6.2.157 / Human Mol. Genet. / Point mutations and an intragenic deletion in LIS1, the lissencephaly causative gene in isolated lissencephaly sequence and Miller-Dieker syndrome by Lo Nigro (1997)
10.1126/science.252.5009.1162 / Science / Predicting coiled coils from protein sequences by Lupas (1991)
10.1046/j.1365-2958.1999.01421.x / Mol. Microbiol. / Neurospora crassa ro-10 and ro-11 genes encode novel proteins required for nuclear distribution by Minke (1999)
10.1083/jcb.148.6.1097 / J. Cell Biol. / Nuclear migration by Morris (2000)
10.1016/S0960-9822(98)70232-5 / Curr. Biol. / The lissencephaly gene Lis1, a protein involved in neuronal migration, interacts with a nuclear movement protein, NudC by Morris (1998)
10.1038/371297a0 / Nature / The ancient regulatory-protein family of WD-repeat proteins by Neer (1994)
10.1073/pnas.95.11.5865 / Proc. Natl. Acad. Sci. USA / Highly specific protein sequence motifs for genome analysis by Nevill-Manning (1998)
10.1016/S0896-6273(00)00147-1 / Neuron / NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein by Niethammer (2000)
10.1016/0092-8674(95)90538-3 / Cell / The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for antegrade axonal transport of synaptic vesicle precursor by Okada (1995)
10.1073/pnas.93.20.11173 / Proc. Natl. Acad. Sci. USA / Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death by Ohshima (1996)
10.1038/330181a0 / Nature / Retrograde transport by the microtubule-associated protein MAP 1C by Paschal (1987)
10.1016/0076-6879(91)96018-M / Methods Enzymol. / Purification of brain cytoplasmic dynein and characterization of its in vitro properties by Paschal (1991)
10.1038/45159 / Nature / Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration by Patrick (1999)
10.1016/S0021-9258(19)49492-1 / J. Biol. Chem. / Brain proline-directed protein kinase phosphorylates tau on sites that are abnormally phosphorylated in tau associated with Alzheimer's paired helical filaments by Paudel (1993)
10.1146/annurev.cb.05.110189.001003 / Annu. Rev. Cell Biol. / Dynein structure and function by Porter (1989)
10.1074/jbc.273.4.2329 / J. Biol. Chem. / Association of neurofilament proteins with neuronal Cdk5 activator by Qi (1998)
10.1016/0896-6273(95)90258-9 / Neuron / Cortical development by Rakic (1995)
10.1038/364717a0 / Nature / Isolation of a Miller-Dieker lissencephaly gene containing G protein b-subunit-like repeat by Reiner (1993)
10.1523/JNEUROSCI.15-05-03730.1995 / J. Neurosci. / Lissencephaly gene (Lis1) expression in the CNS suggests a role in neuronal migration by Reiner (1995)
10.1101/gad.13.21.2758 / Genes Dev. / Mutant mice with scrambled brains by Rice (1999)
10.1021/bi972746o / Biochemistry / Site-specific phosphorylation of Lys-Ser-Pro repeat peptides from neurofilament H by cyclin-dependent kinase 5 by Sharma (1998)
10.1002/(SICI)1097-0134(20000401)39:1<1::AID-PROT1>3.0.CO;2-N / Proteins / Homologs of the alpha- and beta-subunits of mammalian brain platelet-activating factor acetylhydrolase Ib in the Drosophila melanogaster genome by Sheffield (2000)
10.1038/39601 / Nature / Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice by Sheldon (1997)
10.1038/35041000 / Nat. Cell Biol. / Regulation of cytoplasmic dynein behavior and mirotubule organization by mammalian Lis1 by Smith (2000)
10.1016/S0960-9822(06)00157-6 / Curr. Biol. / Systematic identification of mitotic phoshoproteins by Stukenberg (1997)
10.1046/j.1365-2958.1997.5131873.x / Mol. Microbiol. / Nuclear traffic in fungal hyphae by Suelmann (1997)
10.1038/15680 / Nat. Cell Biol. / Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning by Swan (1999)
10.1016/S0092-8674(00)80782-5 / Cell / Reeler/disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2 by Trommsdorff (1999)
10.1146/annurev.bi.59.070190.004401 / Annu. Rev. Biochem. / Motor proteins of cytoplasmic microtubules by Vallee (1990)
10.1016/S0167-4889(00)00011-2 / Biochem. Biophys. Acta / The role of cytoplasmic dynein in the human brain developmental disease lissencephaly by Vallee (2000)
10.1007/s004380050489 / Mol. Gen. Genet. / Mutations in the heavy chain of cytoplasmic dynein suppress the nudF nuclear migration mutation of Aspergillus nidulans by Willins (1997)
10.1006/geno.1998.5427 / Genomics / Chromosomal localization reveals three kinesin heavy chain genes in mouse by Xia (1998)
10.1073/pnas.91.6.2100 / Proc. Natl. Acad. Sci. USA / Cytoplasmic dynein is involved in nuclear migration in A. nidulans by Xiang (1994)
10.1091/mbc.6.3.297 / Mol. Biol. Cell / NudF, a nuclear migration gene in Aspergillus nidulans, is similar to the human LIS-1 gene required for neuronal migration by Xiang (1995)

Dates

Type	When
Created	21 years, 4 months ago (April 15, 2004, 5:36 a.m.)
Deposited	4 years, 2 months ago (June 15, 2021, 12:31 p.m.)
Indexed	28 minutes ago (Sept. 3, 2025, 7:15 a.m.)
Issued	24 years, 9 months ago (Dec. 1, 2000)
Published	24 years, 9 months ago (Dec. 1, 2000)
Published Print	24 years, 9 months ago (Dec. 1, 2000)

Funders 0

None

BibTeX

@article{Sasaki_2000, title={A LIS1/NUDEL/Cytoplasmic Dynein Heavy Chain Complex in the Developing and Adult Nervous System}, volume={28}, ISSN={0896-6273}, url={http://dx.doi.org/10.1016/s0896-6273(00)00146-x}, DOI={10.1016/s0896-6273(00)00146-x}, number={3}, journal={Neuron}, publisher={Elsevier BV}, author={Sasaki, Shinji and Shionoya, Aki and Ishida, Michiyo and Gambello, Michael J. and Yingling, Jessica and Wynshaw-Boris, Anthony and Hirotsune, Shinji}, year={2000}, month=dec, pages={681–696} }

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      "article-title": "A protein related to extracellular matrix proteins deleted in the mice mutant reeler",
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      "journal-title": "Nature"
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      "article-title": "Lissencephaly. A human brain malformation associated with deletion of the LIS1 gene located at chromosome 17p13",
      "volume": "270",
      "author": "Dobyns",
      "year": "1993",
      "journal-title": "J. Am. Med. Assoc."
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      "volume": "150",
      "author": "Efimov",
      "year": "2000",
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      "year": "2000",
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      "volume": "7",
      "author": "Goffinet",
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      "year": "2000",
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      "author": "Neer",
      "year": "1994",
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      "author": "Nevill-Manning",
      "year": "1998",
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      "article-title": "The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for antegrade axonal transport of synaptic vesicle precursor",
      "volume": "81",
      "author": "Okada",
      "year": "1995",
      "journal-title": "Cell"
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      "DOI": "10.1073/pnas.93.20.11173",
      "article-title": "Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death",
      "volume": "93",
      "author": "Ohshima",
      "year": "1996",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
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      "doi-asserted-by": "crossref",
      "first-page": "181",
      "DOI": "10.1038/330181a0",
      "article-title": "Retrograde transport by the microtubule-associated protein MAP 1C",
      "volume": "330",
      "author": "Paschal",
      "year": "1987",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB52",
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      "first-page": "181",
      "DOI": "10.1016/0076-6879(91)96018-M",
      "article-title": "Purification of brain cytoplasmic dynein and characterization of its in vitro properties",
      "volume": "196",
      "author": "Paschal",
      "year": "1991",
      "journal-title": "Methods Enzymol."
    },
    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "615",
      "DOI": "10.1038/45159",
      "article-title": "Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration",
      "volume": "402",
      "author": "Patrick",
      "year": "1999",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "23512",
      "DOI": "10.1016/S0021-9258(19)49492-1",
      "article-title": "Brain proline-directed protein kinase phosphorylates tau on sites that are abnormally phosphorylated in tau associated with Alzheimer's paired helical filaments",
      "volume": "268",
      "author": "Paudel",
      "year": "1993",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "199",
      "DOI": "10.1146/annurev.cb.05.110189.001003",
      "article-title": "Dynein structure and function",
      "volume": "5",
      "author": "Porter",
      "year": "1989",
      "journal-title": "Annu. Rev. Cell Biol."
    },
    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "2329",
      "DOI": "10.1074/jbc.273.4.2329",
      "article-title": "Association of neurofilament proteins with neuronal Cdk5 activator",
      "volume": "273",
      "author": "Qi",
      "year": "1998",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB34",
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      "first-page": "1101",
      "DOI": "10.1016/0896-6273(95)90258-9",
      "article-title": "Cortical development",
      "volume": "14",
      "author": "Rakic",
      "year": "1995",
      "journal-title": "Neuron"
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    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB35",
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      "first-page": "717",
      "DOI": "10.1038/364717a0",
      "article-title": "Isolation of a Miller-Dieker lissencephaly gene containing G protein b-subunit-like repeat",
      "volume": "364",
      "author": "Reiner",
      "year": "1993",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "3730",
      "DOI": "10.1523/JNEUROSCI.15-05-03730.1995",
      "article-title": "Lissencephaly gene (Lis1) expression in the CNS suggests a role in neuronal migration",
      "volume": "15",
      "author": "Reiner",
      "year": "1995",
      "journal-title": "J. Neurosci."
    },
    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB37",
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      "first-page": "2758",
      "DOI": "10.1101/gad.13.21.2758",
      "article-title": "Mutant mice with scrambled brains",
      "volume": "13",
      "author": "Rice",
      "year": "1999",
      "journal-title": "Genes Dev."
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    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB38",
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      "first-page": "4759",
      "DOI": "10.1021/bi972746o",
      "article-title": "Site-specific phosphorylation of Lys-Ser-Pro repeat peptides from neurofilament H by cyclin-dependent kinase 5",
      "volume": "37",
      "author": "Sharma",
      "year": "1998",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB39",
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      "DOI": "10.1002/(SICI)1097-0134(20000401)39:1<1::AID-PROT1>3.0.CO;2-N",
      "article-title": "Homologs of the alpha- and beta-subunits of mammalian brain platelet-activating factor acetylhydrolase Ib in the Drosophila melanogaster genome",
      "volume": "39",
      "author": "Sheffield",
      "year": "2000",
      "journal-title": "Proteins"
    },
    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB40",
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      "first-page": "730",
      "DOI": "10.1038/39601",
      "article-title": "Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice",
      "volume": "389",
      "author": "Sheldon",
      "year": "1997",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "767",
      "DOI": "10.1038/35041000",
      "article-title": "Regulation of cytoplasmic dynein behavior and mirotubule organization by mammalian Lis1",
      "volume": "2",
      "author": "Smith",
      "year": "2000",
      "journal-title": "Nat. Cell Biol."
    },
    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB42",
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      "first-page": "338",
      "DOI": "10.1016/S0960-9822(06)00157-6",
      "article-title": "Systematic identification of mitotic phoshoproteins",
      "volume": "7",
      "author": "Stukenberg",
      "year": "1997",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB43",
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      "first-page": "757",
      "DOI": "10.1046/j.1365-2958.1997.5131873.x",
      "article-title": "Nuclear traffic in fungal hyphae",
      "volume": "25",
      "author": "Suelmann",
      "year": "1997",
      "journal-title": "Mol. Microbiol."
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      "key": "10.1016/S0896-6273(00)00146-X_BIB44",
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      "first-page": "444",
      "DOI": "10.1038/15680",
      "article-title": "Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning",
      "volume": "1",
      "author": "Swan",
      "year": "1999",
      "journal-title": "Nat. Cell Biol."
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      "first-page": "689",
      "DOI": "10.1016/S0092-8674(00)80782-5",
      "article-title": "Reeler/disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2",
      "volume": "97",
      "author": "Trommsdorff",
      "year": "1999",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB46",
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      "first-page": "909",
      "DOI": "10.1146/annurev.bi.59.070190.004401",
      "article-title": "Motor proteins of cytoplasmic microtubules",
      "volume": "59",
      "author": "Vallee",
      "year": "1990",
      "journal-title": "Annu. Rev. Biochem."
    },
    {
      "key": "10.1016/S0896-6273(00)00146-X_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "89",
      "DOI": "10.1016/S0167-4889(00)00011-2",
      "article-title": "The role of cytoplasmic dynein in the human brain developmental disease lissencephaly",
      "volume": "1496",
      "author": "Vallee",
      "year": "2000",
      "journal-title": "Biochem. Biophys. Acta"
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      "DOI": "10.1007/s004380050489",
      "article-title": "Mutations in the heavy chain of cytoplasmic dynein suppress the nudF nuclear migration mutation of Aspergillus nidulans",
      "volume": "255",
      "author": "Willins",
      "year": "1997",
      "journal-title": "Mol. Gen. Genet."
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      "first-page": "209",
      "DOI": "10.1006/geno.1998.5427",
      "article-title": "Chromosomal localization reveals three kinesin heavy chain genes in mouse",
      "volume": "52",
      "author": "Xia",
      "year": "1998",
      "journal-title": "Genomics"
    },
    {
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      "first-page": "2100",
      "DOI": "10.1073/pnas.91.6.2100",
      "article-title": "Cytoplasmic dynein is involved in nuclear migration in A. nidulans",
      "volume": "91",
      "author": "Xiang",
      "year": "1994",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
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      "DOI": "10.1091/mbc.6.3.297",
      "article-title": "NudF, a nuclear migration gene in Aspergillus nidulans, is similar to the human LIS-1 gene required for neuronal migration",
      "volume": "6",
      "author": "Xiang",
      "year": "1995",
      "journal-title": "Mol. Biol. Cell"
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