DOI: 10.1016/s0378-1119(01)00599-6. Identification and characterization of two novel calpain large subunit genes

Identification and characterization of two novel calpain large subunit genes

10.1016/s0378-1119(01)00599-6

Crossref journal-article

Elsevier BV

Gene (78)

Bibliography

Dear, T. N., & Boehm, T. (2001). Identification and characterization of two novel calpain large subunit genes. Gene, 274(1â2), 245â252.

Authors 2

T.Neil Dear (first)
Thomas Boehm (additional)

References 27 Referenced 62

10.1016/S0022-2836(05)80360-2 / J. Mol. Biol. / Basic local alignment sequencing tool by Altschul (1990)
10.1128/MCB.20.12.4474-4481.2000 / Mol. Cell. Biol. / Disruption of the murine calpain small subunit gene. Capn4: calpain is essential for embryonic development but not for cell growth and division by Arthur (2000)
10.1128/MCB.21.6.2213-2220.2001 / Mol. Cell. Biol. / Disruption of the mouse μ-calpain gene reveals an essential role in platelet function by Azam (2001)
10.1038/nsb0797-532 / Nat. Struct. Biol. / Structure of a Ca2+-binding domain reveals a novel EF-hand and Ca2+-induced conformational changes by Blanchard (1997)
10.1006/bbrc.1999.0948 / Biochem. Biophys. Res. Commun. / CAPN 8: isolation of a new mouse calpain-isoenzyme by Braun (1999)
10.1016/0003-2697(87)90021-2 / Anal. Biochem. / Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction by Chomczynski (1987)
10.1006/geno.1997.4870 / Genomics / A new subfamily of vertebrate calpains lacking a calmodulin-like domain: implications for calpain regulation and evolution by Dear (1997)
10.1006/geno.1999.5859 / Genomics / CAPN11: a calpain with high mRNA levels in testis and located on chromosome 6 by Dear (1999)
10.1006/geno.2000.6289 / Genomics / Gene structure, chromosomal localization and expression pattern of Capn12, a new member of the calpain large subunit gene family by Dear (2000)
10.1007/s003359900995 / Mamm. Genome / Capn7: a highly divergent vertebrate calpain with a novel C-terminal domain by Franz (1999)
10.1038/79876 / Nat. Genet. / Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus by Horikawa (2000)
10.1093/emboj/18.24.6880 / EMBO J. / Crystal structure of calpain reveals the structural basis for Ca2+-dependent protease activity and a novel mode of enzyme activation by Hosfield (1999)
10.1007/PL00006549 / J. Mol. Evol. / The evolution of the calpain family as reflected in paralogous chromosome regions by Jékely (1999)
10.1006/geno.1998.5395 / Genomics / SOLH, a human homologue of the Drosophila melanogaster small optic lobes gene is a member of the calpain and zinc-finger gene families and maps to human chromosome 16p13.3 near CATM (cataract with microphthalmia) by Kamei (1998)
10.1038/35057062 / Nature / Initial sequencing and analysis of the human genome. International Human Genome Sequencing Consortium by Lander (2001)
10.1515/bchm.1998.379.2.175 / Biol. Chem. / Molecular cloning and characterization of a novel tissue-specific calpain predominantly expressed in the digestive tract by Lee (1998)
10.1038/nsb0797-539 / Nat. Struct. Biol. / Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding by Lin (1997)
10.1074/jbc.M005451200 / J. Biol. Chem. / Antisense RNA-mediated deficiency of the calpain protease, nCL-4, in NIH3T3 cells is associated with neoplastic transformation and tumorigenesis by Liu (2000)
10.1007/BF02346182 / Hum. Genet. / Genetic mapping studies of 40 loci and 23 cosmids in chromosome 11p13-11q13, and exclusion of mu-calpain as the multiple endocrine neoplasia type 1 gene by Pang (1996)
10.1016/0092-8674(95)90368-2 / Cell / Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A by Richard (1995)
10.1083/jcb.151.7.1583 / J. Cell Biol. / Loss of calpain 3 proteolytic activity leads to muscular dystrophy and to apoptosis-associated IkappaBalpha/nuclear factor kappaB pathway perturbation in mice by Richard (2000)
10.1074/jbc.273.26.15879 / J. Biol. Chem. / C2-domains, structure and function of a universal Ca2+-binding domain by Rizo (1998)
10.1093/oxfordjournals.jbchem.a002903 / J. Biochem. / The structure of calpain by Sorimachi (2001)
10.1073/pnas.97.2.588 / Proc. Natl. Acad. Sci. USA / The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium by Strobl (2000)
10.1093/nar/22.22.4673 / Nucleic Acids Res. / CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice by Thompson (1994)
10.1126/science.1058040 / Science / The sequence of the human genome by Venter (2001)
{'key': '10.1016/S0378-1119(01)00599-6_BIB27', 'first-page': '63', 'article-title': 'The calpain small subunit gene is essential: its inactivation results in embryonic lethality', 'volume': '50', 'author': 'Zimmerman', 'year': '2000', 'journal-title': 'Biochem. Mol. Biol. Int.'} / Biochem. Mol. Biol. Int. / The calpain small subunit gene is essential: its inactivation results in embryonic lethality by Zimmerman (2000)

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 1:23 p.m.)
Deposited	6 years, 4 months ago (April 24, 2019, 8:31 p.m.)
Indexed	1 month, 1 week ago (July 24, 2025, 8:22 a.m.)
Issued	24 years, 1 month ago (Aug. 1, 2001)
Published	24 years, 1 month ago (Aug. 1, 2001)
Published Print	24 years, 1 month ago (Aug. 1, 2001)

Funders 0

None

BibTeX

@article{Dear_2001, title={Identification and characterization of two novel calpain large subunit genes}, volume={274}, ISSN={0378-1119}, url={http://dx.doi.org/10.1016/s0378-1119(01)00599-6}, DOI={10.1016/s0378-1119(01)00599-6}, number={1–2}, journal={Gene}, publisher={Elsevier BV}, author={Dear, T.Neil and Boehm, Thomas}, year={2001}, month=aug, pages={245–252} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        7,
        24
      ]
    ],
    "date-time": "2025-07-24T12:22:37Z",
    "timestamp": 1753359757562
  },
  "reference-count": 27,
  "publisher": "Elsevier BV",
  "issue": "1-2",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2001,
            8,
            1
          ]
        ],
        "date-time": "2001-08-01T00:00:00Z",
        "timestamp": 996624000000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2001,
        8
      ]
    ]
  },
  "DOI": "10.1016/s0378-1119(01)00599-6",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        25
      ]
    ],
    "date-time": "2002-07-25T17:23:01Z",
    "timestamp": 1027617781000
  },
  "page": "245-252",
  "source": "Crossref",
  "is-referenced-by-count": 62,
  "title": "Identification and characterization of two novel calpain large subunit genes",
  "prefix": "10.1016",
  "volume": "274",
  "author": [
    {
      "given": "T.Neil",
      "family": "Dear",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Thomas",
      "family": "Boehm",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB1",
      "doi-asserted-by": "crossref",
      "first-page": "403",
      "DOI": "10.1016/S0022-2836(05)80360-2",
      "article-title": "Basic local alignment sequencing tool",
      "volume": "215",
      "author": "Altschul",
      "year": "1990",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB2",
      "doi-asserted-by": "crossref",
      "first-page": "4474",
      "DOI": "10.1128/MCB.20.12.4474-4481.2000",
      "article-title": "Disruption of the murine calpain small subunit gene. Capn4: calpain is essential for embryonic development but not for cell growth and division",
      "volume": "20",
      "author": "Arthur",
      "year": "2000",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB3",
      "doi-asserted-by": "crossref",
      "first-page": "2213",
      "DOI": "10.1128/MCB.21.6.2213-2220.2001",
      "article-title": "Disruption of the mouse \u03bc-calpain gene reveals an essential role in platelet function",
      "volume": "21",
      "author": "Azam",
      "year": "2001",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB4",
      "doi-asserted-by": "crossref",
      "first-page": "532",
      "DOI": "10.1038/nsb0797-532",
      "article-title": "Structure of a Ca2+-binding domain reveals a novel EF-hand and Ca2+-induced conformational changes",
      "volume": "4",
      "author": "Blanchard",
      "year": "1997",
      "journal-title": "Nat. Struct. Biol."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB5",
      "doi-asserted-by": "crossref",
      "first-page": "671",
      "DOI": "10.1006/bbrc.1999.0948",
      "article-title": "CAPN 8: isolation of a new mouse calpain-isoenzyme",
      "volume": "260",
      "author": "Braun",
      "year": "1999",
      "journal-title": "Biochem. Biophys. Res. Commun."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB6",
      "doi-asserted-by": "crossref",
      "first-page": "156",
      "DOI": "10.1016/0003-2697(87)90021-2",
      "article-title": "Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction",
      "volume": "162",
      "author": "Chomczynski",
      "year": "1987",
      "journal-title": "Anal. Biochem."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB7",
      "doi-asserted-by": "crossref",
      "first-page": "175",
      "DOI": "10.1006/geno.1997.4870",
      "article-title": "A new subfamily of vertebrate calpains lacking a calmodulin-like domain: implications for calpain regulation and evolution",
      "volume": "45",
      "author": "Dear",
      "year": "1997",
      "journal-title": "Genomics"
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB8",
      "doi-asserted-by": "crossref",
      "first-page": "243",
      "DOI": "10.1006/geno.1999.5859",
      "article-title": "CAPN11: a calpain with high mRNA levels in testis and located on chromosome 6",
      "volume": "59",
      "author": "Dear",
      "year": "1999",
      "journal-title": "Genomics"
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB9",
      "doi-asserted-by": "crossref",
      "first-page": "152",
      "DOI": "10.1006/geno.2000.6289",
      "article-title": "Gene structure, chromosomal localization and expression pattern of Capn12, a new member of the calpain large subunit gene family",
      "volume": "68",
      "author": "Dear",
      "year": "2000",
      "journal-title": "Genomics"
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB10",
      "doi-asserted-by": "crossref",
      "first-page": "318",
      "DOI": "10.1007/s003359900995",
      "article-title": "Capn7: a highly divergent vertebrate calpain with a novel C-terminal domain",
      "volume": "10",
      "author": "Franz",
      "year": "1999",
      "journal-title": "Mamm. Genome"
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB11",
      "doi-asserted-by": "crossref",
      "first-page": "163",
      "DOI": "10.1038/79876",
      "article-title": "Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus",
      "volume": "26",
      "author": "Horikawa",
      "year": "2000",
      "journal-title": "Nat. Genet."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB12",
      "doi-asserted-by": "crossref",
      "first-page": "6880",
      "DOI": "10.1093/emboj/18.24.6880",
      "article-title": "Crystal structure of calpain reveals the structural basis for Ca2+-dependent protease activity and a novel mode of enzyme activation",
      "volume": "18",
      "author": "Hosfield",
      "year": "1999",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB13",
      "doi-asserted-by": "crossref",
      "first-page": "272",
      "DOI": "10.1007/PL00006549",
      "article-title": "The evolution of the calpain family as reflected in paralogous chromosome regions",
      "volume": "49",
      "author": "J\u00e9kely",
      "year": "1999",
      "journal-title": "J. Mol. Evol."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB14",
      "doi-asserted-by": "crossref",
      "first-page": "197",
      "DOI": "10.1006/geno.1998.5395",
      "article-title": "SOLH, a human homologue of the Drosophila melanogaster small optic lobes gene is a member of the calpain and zinc-finger gene families and maps to human chromosome 16p13.3 near CATM (cataract with microphthalmia)",
      "volume": "51",
      "author": "Kamei",
      "year": "1998",
      "journal-title": "Genomics"
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB15",
      "doi-asserted-by": "crossref",
      "first-page": "860",
      "DOI": "10.1038/35057062",
      "article-title": "Initial sequencing and analysis of the human genome. International Human Genome Sequencing Consortium",
      "volume": "409",
      "author": "Lander",
      "year": "2001",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB16",
      "doi-asserted-by": "crossref",
      "first-page": "175",
      "DOI": "10.1515/bchm.1998.379.2.175",
      "article-title": "Molecular cloning and characterization of a novel tissue-specific calpain predominantly expressed in the digestive tract",
      "volume": "379",
      "author": "Lee",
      "year": "1998",
      "journal-title": "Biol. Chem."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB17",
      "doi-asserted-by": "crossref",
      "first-page": "539",
      "DOI": "10.1038/nsb0797-539",
      "article-title": "Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding",
      "volume": "4",
      "author": "Lin",
      "year": "1997",
      "journal-title": "Nat. Struct. Biol."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "31093",
      "DOI": "10.1074/jbc.M005451200",
      "article-title": "Antisense RNA-mediated deficiency of the calpain protease, nCL-4, in NIH3T3 cells is associated with neoplastic transformation and tumorigenesis",
      "volume": "275",
      "author": "Liu",
      "year": "2000",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "732",
      "DOI": "10.1007/BF02346182",
      "article-title": "Genetic mapping studies of 40 loci and 23 cosmids in chromosome 11p13-11q13, and exclusion of mu-calpain as the multiple endocrine neoplasia type 1 gene",
      "volume": "97",
      "author": "Pang",
      "year": "1996",
      "journal-title": "Hum. Genet."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB20",
      "doi-asserted-by": "crossref",
      "first-page": "27",
      "DOI": "10.1016/0092-8674(95)90368-2",
      "article-title": "Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A",
      "volume": "81",
      "author": "Richard",
      "year": "1995",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "1583",
      "DOI": "10.1083/jcb.151.7.1583",
      "article-title": "Loss of calpain 3 proteolytic activity leads to muscular dystrophy and to apoptosis-associated IkappaBalpha/nuclear factor kappaB pathway perturbation in mice",
      "volume": "151",
      "author": "Richard",
      "year": "2000",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "15879",
      "DOI": "10.1074/jbc.273.26.15879",
      "article-title": "C2-domains, structure and function of a universal Ca2+-binding domain",
      "volume": "273",
      "author": "Rizo",
      "year": "1998",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "653",
      "DOI": "10.1093/oxfordjournals.jbchem.a002903",
      "article-title": "The structure of calpain",
      "volume": "129",
      "author": "Sorimachi",
      "year": "2001",
      "journal-title": "J. Biochem."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "588",
      "DOI": "10.1073/pnas.97.2.588",
      "article-title": "The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium",
      "volume": "97",
      "author": "Strobl",
      "year": "2000",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "4673",
      "DOI": "10.1093/nar/22.22.4673",
      "article-title": "CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice",
      "volume": "22",
      "author": "Thompson",
      "year": "1994",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "1304",
      "DOI": "10.1126/science.1058040",
      "article-title": "The sequence of the human genome",
      "volume": "291",
      "author": "Venter",
      "year": "2001",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0378-1119(01)00599-6_BIB27",
      "first-page": "63",
      "article-title": "The calpain small subunit gene is essential: its inactivation results in embryonic lethality",
      "volume": "50",
      "author": "Zimmerman",
      "year": "2000",
      "journal-title": "Biochem. Mol. Biol. Int."
    }
  ],
  "container-title": "Gene",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0378111901005996?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0378111901005996?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2019,
        4,
        25
      ]
    ],
    "date-time": "2019-04-25T00:31:51Z",
    "timestamp": 1556152311000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0378111901005996"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2001,
        8
      ]
    ]
  },
  "references-count": 27,
  "journal-issue": {
    "issue": "1-2",
    "published-print": {
      "date-parts": [
        [
          2001,
          8
        ]
      ]
    }
  },
  "alternative-id": [
    "S0378111901005996"
  ],
  "URL": "http://dx.doi.org/10.1016/S0378-1119(01)00599-6",
  "relation": {},
  "ISSN": [
    "0378-1119"
  ],
  "subject": [],
  "container-title-short": "Gene",
  "published": {
    "date-parts": [
      [
        2001,
        8
      ]
    ]
  }
}