DOI: 10.1016/s0304-3940(02)00448-2. Allopregnanolone attenuates N -methyl- d -aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture

Allopregnanolone attenuates N -methyl- d -aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture

10.1016/s0304-3940(02)00448-2

Crossref journal-article

Elsevier BV

Neuroscience Letters (78)

Bibliography

Lockhart, E. M., Warner, D. S., Pearlstein, R. D., Penning, D. H., Mehrabani, S., & Boustany, R.-M. (2002). Allopregnanolone attenuates N -methyl- d -aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture. Neuroscience Letters, 328(1), 33â36.

Authors 6

Ellen M. Lockhart (first)
David S. Warner (additional)
Robert D. Pearlstein (additional)
Donald H. Penning (additional)
Saeed Mehrabani (additional)
Rose-Mary Boustany (additional)

References 22 Referenced 69

10.1097/00000542-200003000-00020 / Anesthesiology / Effect of barbiturates on hydroxyl radicals, lipid peroxidation, and hypoxic cell death in human NT2-N neurons by Almaas (2000)
10.1093/clinchem/9.4.391 / Clin. Chem. / Serum lactic dehydrogenase activity: an analytical assessment of current assay by Amador (1963)
10.1016/0014-2999(89)90077-0 / Eur. J. Pharmacol. / Anticonvulsant profile of the progesterone metabolite 5 alpha-pregnan-3 alpha-ol-20-one by Belelli (1989)
10.1073/pnas.95.22.13284 / Proc. Natl. Acad. Sci. USA / Role of allopregnanolone in the plasticity of gamma-aminobutyric acid type A receptor in the rat brain during pregnancy and after delivery by Concas (1998)
10.1016/S0278-5846(00)00124-X / Prog. Neuropsychopharmacol. Biol. Psychiatry / Neuroprotective effects of allopregnanolone on hippocampal irreversible neurotoxicity in vitro by Frank (2000)
10.1023/A:1007668213330 / Neurochem. Res. / Pregnenolone protects mouse hippocampal (HT-22) cells against glutamate and amyloid beta protein toxicity by Gursoy (2001)
10.1016/S0165-3806(97)00192-2 / Brain Res. / Chronic hypoxemia causes extracellular glutamate concentration to increase in the cerebral cortex of the near-term fetal sheep by Henderson (1998)
10.1016/0006-8993(96)00605-1 / Brain Res. / Progesterone is neuroprotective after transient middle cerebral artery occlusion in male rats by Jiang (1996)
10.1016/0024-3205(96)00314-1 / Life Sci. / Calcium-related damage in ischemia by Kristian (1996)
10.1016/S0165-6147(00)89058-6 / Trends Pharmacol. Sci. / Neurosteroids and GABAA receptor function by Lambert (1995)
10.1210/jcem.85.7.6675 / J. Clin. Endocrinol. Metab. / Serum allopregnanolone levels in pregnant women: changes during pregnancy, at delivery, and in hypertensive patients by Luisi (2000)
10.1016/0006-8993(90)91792-F / Brain Res. / Evidence that 5A-pregnan-3A-ol-20-one is the metabolite responsible for progesterone anesthesia by Mok (1990)
10.1523/JNEUROSCI.15-12-07847.1995 / J. Neurosci. / Excitotoxic cell death and delayed rescue in human neurons derived from NT2 cells by Munir (1995)
10.1523/JNEUROSCI.18-13-04993.1998 / J. Neurosci. / GABAA receptor pharmacology and subtype mRNA expression in human neuronal NT2-N cells by Neelands (1998)
10.1016/0306-4522(93)90513-F / Neuroscience / Steroid hormones protect spinal cord neurons from glutamate toxicity by Ogata (1993)
10.1097/00000542-199502000-00022 / Anesthesiology / Glutamate release from the ovine fetal brain during maternal hemorrhage: a study utilizing chronic in utero cerebral microdialysis by Penning (1995)
10.1007/BF02815156 / Mol. Chem. Neuropathol. / Progesterone protects against lipid peroxidation following traumatic brain injury in rats by Roof (1997)
10.1016/0306-4522(91)90377-Z / Neuroscience / Progesterone administration attenuates excitatory amino acid responses of cerebellar Purkinje cells by Smith (1991)
10.1523/JNEUROSCI.20-19-07183.2000 / J. Neurosci. / Transient NMDA receptor inactivation provides long-term protection to cultured cortical neurons from a variety of death signals by Tremblay (2000)
10.1177/108705710100600607 / J. Biomol. Screen. / High throughput fluorescence assays for the measurement of mitochondrial activity in intact human neuroblastoma cells by Woollacott (2001)
{'key': '10.1016/S0304-3940(02)00448-2_BIB21', 'series-title': 'Maternal–Fetal Medicine: Principles and Practice', 'first-page': '331', 'article-title': 'Endocrine and other evaluations of the fetal environment', 'author': 'Yen', 'year': '1984'} / Maternal–Fetal Medicine: Principles and Practice / Endocrine and other evaluations of the fetal environment by Yen (1984)
10.1073/pnas.90.6.2174 / Proc. Natl. Acad. Sci. USA / Inducible expression of neuronal glutamate receptor channels in the NT2 human cell line by Younkin (1993)

Dates

Type	When
Created	22 years, 10 months ago (Oct. 14, 2002, 3:11 p.m.)
Deposited	5 years, 7 months ago (Feb. 4, 2020, 10:19 p.m.)
Indexed	4 days, 14 hours ago (Sept. 2, 2025, 6:35 a.m.)
Issued	23 years, 1 month ago (Aug. 1, 2002)
Published	23 years, 1 month ago (Aug. 1, 2002)
Published Print	23 years, 1 month ago (Aug. 1, 2002)

Funders 0

None

BibTeX

@article{Lockhart_2002, title={Allopregnanolone attenuates N -methyl- d -aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture}, volume={328}, ISSN={0304-3940}, url={http://dx.doi.org/10.1016/s0304-3940(02)00448-2}, DOI={10.1016/s0304-3940(02)00448-2}, number={1}, journal={Neuroscience Letters}, publisher={Elsevier BV}, author={Lockhart, Ellen M. and Warner, David S. and Pearlstein, Robert D. and Penning, Donald H. and Mehrabani, Saeed and Boustany, Rose-Mary}, year={2002}, month=aug, pages={33–36} }

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