DOI: 10.1016/s0300-483x(99)00176-6. Cadmium induces caspase-mediated cell death: suppression by Bcl-2

Cadmium induces caspase-mediated cell death: suppression by Bcl-2

10.1016/s0300-483x(99)00176-6

Crossref journal-article

Elsevier BV

Toxicology (78)

Bibliography

Kim, M. S., Kim, B. J., Woo, H. N., Kim, K. W., Kim, K. B., Kim, I. K., & Jung, Y. K. (2000). Cadmium induces caspase-mediated cell death: suppression by Bcl-2. Toxicology, 145(1), 27â37.

Authors 7

M.S. Kim (first)
B.J. Kim (additional)
H.N. Woo (additional)
K.W. Kim (additional)
K.B. Kim (additional)
I.K. Kim (additional)
Y.K. Jung (additional)

References 43 Referenced 82

10.1038/sj.cdd.4400445 / Cell Death Differ. / Induction of apoptosis by the novel retinoid AHPN in human T-cell lymphoma cells involves caspase-dependent and independent pathways by Adachi (1998)
{'key': '10.1016/S0300-483X(99)00176-6_BIB2', 'first-page': '5201', 'article-title': 'Identification and characterization of murine caspase-14, a new member of the caspase family', 'volume': '58', 'author': 'Ahmad', 'year': '1998', 'journal-title': 'Cancer Res.'} / Cancer Res. / Identification and characterization of murine caspase-14, a new member of the caspase family by Ahmad (1998)
10.1016/S0092-8674(00)81334-3 / Cell / Human ICE/CED-3 protease nomenclature by Alnemri (1996)
10.1016/S0165-6147(97)89797-0 / Trends Pharmacol. Sci. / Bcl-2 related proteins, apoptosis and disease by Anderson (1997)
10.1006/scbi.1995.0002 / Semin. Cancer Biol. / Cell death in health and disease: the biology and regulation of apoptosis by Bellamy (1995)
10.1016/S0300-9084(97)82011-1 / Biochimie / Suppression of apoptosis by overexpression of Bcl-2 or Bcl-xL promotes survival and mutagenesis after oxidative damage by Cherbonnel-Lasserre (1997)
10.2174/0929867306666220320221415 / Curr. Med. Chem. / Modulating apoptosis: current applications and prospects for future drug development by Deigner (1999)
10.1016/0300-483X(94)90115-5 / Toxicology / Cadmium induces apoptosis in a human T cell line by el Azzouzi (1994)
10.1093/genetics/129.1.79 / Genetics / Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans by Ellis (1991)
10.1038/375078a0 / Nature / Involvement of an ICE-like protease in Fas-mediated apoptosis by Enari (1995)
10.1038/380723a0 / Nature / Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis by Enari (1996)
10.1159/000188227 / Nephron / Cytopathological changes induced by cadmium-exposure in canine proximal tubular cells: a cytochemical and ultrastructural study by Hamada (1994)
10.1016/0300-483X(96)03404-X / Toxicology / Cadmium-induced production of superoxide anion and nitric oxide, DNA single strand breaks and lactate dehydrogenase leakage in J774A.1 cell cultures by Hassoun (1996)
10.1074/jbc.273.25.15702 / J. Biol. Chem. / ERICE, a novel FLICE activable caspase by Humke (1998)
{'key': '10.1016/S0300-483X(99)00176-6_BIB15', 'first-page': '529', 'article-title': 'Toxicokinetics and biochemistry of cadmium with special emphasis on the role of metallothionein', 'volume': '19', 'author': 'Jin', 'year': '1998', 'journal-title': 'Neurotoxicology'} / Neurotoxicology / Toxicokinetics and biochemistry of cadmium with special emphasis on the role of metallothionein by Jin (1998)
10.1074/jbc.271.9.5112 / J. Biol. Chem. / Suppression of interleukin-1 beta-converting enzyme-mediated cell death by insulin-like growth factor by Jung (1996)
10.1016/S0092-8674(00)80434-1 / Cell / Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade by Li (1997)
10.1016/S0092-8674(00)81375-6 / Cell / Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death by Liu (1996)
10.1038/375081a0 / Nature / Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis by Los (1995)
10.1016/S0300-483X(98)00043-2 / Toxicology / Methylcholanthene causes increased thymocyte apoptosis by Lutz (1998)
10.1038/ki.1995.306 / Kidney Int. / Cadmium-induced expression of immediate early genes in LLC-PK1 cells by Matsuoka (1995)
10.1016/0896-6273(95)90042-X / Neuron / Peptide inhibitors of the ICE protease family arrest programmed cell death of motoneurons in vivo and in vitro by Milligan (1995)
10.1007/s002040050541 / Arch. Toxicol. / Relationship between the development of hepato-renal toxicity and cadmium accumulation in rats given minimum to large amounts of cadmium chloride in the long-term: preliminary study by Mitsumori (1998)
10.1038/376037a0 / Nature / Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis by Nicholson (1995)
10.1007/s000110050369 / Inflamm. Res. / Apoptosis and autoimmune disease by O'Reilly (1999)
10.1016/S0168-9525(96)30108-X / Trends Genet. / Cell death in vertebrates: lessons from the worm by Osborne (1996)
10.1074/jbc.270.18.10377 / J. Biol. Chem. / Granzyme B is inhibited by the cowpox virus serpin cytokine response modifier A by Quan (1995)
10.1016/0092-8674(92)90223-Y / Cell / Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme by Ray (1992)
10.1002/1531-8249(199904)45:4<421::AID-ANA2>3.0.CO;2-Q / Ann. Neurol. / Caspases as treatment targets in stroke and neurodegenerative diseases by Schulz (1999)
10.1016/S0092-8674(00)80092-6 / Cell / An alternatively spliced C. elegans ced-4 RNA encodes a novel cell death inhibitor by Shaham (1996)
10.1038/20959 / Nature / Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC by Shimizu (1999)
10.1016/0891-5849(94)00159-H / Free Radic. Biol. Med. / Oxidative mechanisms in the toxicity of metal ions by Stohs (1995)
10.1074/jbc.274.8.5053 / J. Biol. Chem. / Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis by Sun (1999)
10.1016/S0005-2728(98)00167-4 / Biochem. Biophys. Acta / Apoptosis in neurodegenerative diseases: the role of mitochondria by Tatton (1999)
10.1126/science.7878464 / Science / Apoptosis in the pathogenesis and treatment of disease by Thompson (1995)
10.1038/356768a0 / Nature / A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes by Thornberry (1992)
10.1038/sj.cdd.4400262 / Cell Death Differ. / Apoptosis and necrosis: intracellular ATP levels as a determinant for cell death modes by Tsujimoto (1997)
10.1093/carcin/20.1.65 / Carcinogenesis / Cadmium-induced inhibition of the growth and metastasis of human lung carcinoma xenografts: role of apoptosis by Waalkes (1999)
10.1242/dev.126.9.2021 / Development / C. elegans MAC-1, an essential member of the AAA family of ATPases, can bind CED-4 and prevent cell death by Wu (1999)
10.1016/0300-483X(95)03195-L / Toxicology / In vivo studies of cadmium-induced apoptosis in testicular tissue of the rat and its modulation by a chelating agent by Xu (1996)
10.1016/0092-8674(93)90485-9 / Cell / The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme by Yuan (1993)
10.1006/excr.1995.1391 / Exp. Cell Res. / Multiple proteases are involved in thymocyte apoptosis by Zhivotovsky (1995)
10.1006/excr.1999.4452 / Exp. Cell Res. / Tumor radiosensitivity and apoptosis by Zhivotovsky (1999)

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 10:20 p.m.)
Deposited	2 years, 4 months ago (April 16, 2023, 6:58 p.m.)
Indexed	2 months, 3 weeks ago (June 10, 2025, 1:26 p.m.)
Issued	25 years, 5 months ago (April 1, 2000)
Published	25 years, 5 months ago (April 1, 2000)
Published Print	25 years, 5 months ago (April 1, 2000)

Funders 0

None

BibTeX

@article{Kim_2000, title={Cadmium induces caspase-mediated cell death: suppression by Bcl-2}, volume={145}, ISSN={0300-483X}, url={http://dx.doi.org/10.1016/s0300-483x(99)00176-6}, DOI={10.1016/s0300-483x(99)00176-6}, number={1}, journal={Toxicology}, publisher={Elsevier BV}, author={Kim, M.S. and Kim, B.J. and Woo, H.N. and Kim, K.W. and Kim, K.B. and Kim, I.K. and Jung, Y.K.}, year={2000}, month=apr, pages={27–37} }

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