DOI: 10.1016/s0168-3659(96)01475-7. Protein-loaded poly(dl-lactide-co-glycolide) microparticles for oral administration: formulation, structural and release characteristics

Protein-loaded poly(dl-lactide-co-glycolide) microparticles for oral administration: formulation, structural and release characteristics

10.1016/s0168-3659(96)01475-7

Crossref journal-article

Elsevier BV

Journal of Controlled Release (78)

Bibliography

Rafati, H., Coombes, A. G. A., Adler, J., Holland, J., & Davis, S. S. (1997). Protein-loaded poly(dl-lactide-co-glycolide) microparticles for oral administration: formulation, structural and release characteristics. Journal of Controlled Release, 43(1), 89â102.

Authors 5

H Rafati (first)
A.G.A Coombes (additional)
J Adler (additional)
J Holland (additional)
S.S Davis (additional)

References 31 Referenced 171

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 8:12 a.m.)
Deposited	6 years, 4 months ago (April 26, 2019, 1 a.m.)
Indexed	1 month ago (Aug. 2, 2025, 1:05 a.m.)
Issued	28 years, 8 months ago (Jan. 1, 1997)
Published	28 years, 8 months ago (Jan. 1, 1997)
Published Print	28 years, 8 months ago (Jan. 1, 1997)

Funders 0

None

BibTeX

@article{Rafati_1997, title={Protein-loaded poly(dl-lactide-co-glycolide) microparticles for oral administration: formulation, structural and release characteristics}, volume={43}, ISSN={0168-3659}, url={http://dx.doi.org/10.1016/s0168-3659(96)01475-7}, DOI={10.1016/s0168-3659(96)01475-7}, number={1}, journal={Journal of Controlled Release}, publisher={Elsevier BV}, author={Rafati, H and Coombes, A.G.A and Adler, J and Holland, J and Davis, S.S}, year={1997}, month=jan, pages={89–102} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        2
      ]
    ],
    "date-time": "2025-08-02T05:05:25Z",
    "timestamp": 1754111125669
  },
  "reference-count": 31,
  "publisher": "Elsevier BV",
  "issue": "1",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            1997,
            1,
            1
          ]
        ],
        "date-time": "1997-01-01T00:00:00Z",
        "timestamp": 852076800000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1997,
        1
      ]
    ]
  },
  "DOI": "10.1016/s0168-3659(96)01475-7",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        7,
        25
      ]
    ],
    "date-time": "2002-07-25T12:12:02Z",
    "timestamp": 1027599122000
  },
  "page": "89-102",
  "source": "Crossref",
  "is-referenced-by-count": 171,
  "title": "Protein-loaded poly(dl-lactide-co-glycolide) microparticles for oral administration: formulation, structural and release characteristics",
  "prefix": "10.1016",
  "volume": "43",
  "author": [
    {
      "given": "H",
      "family": "Rafati",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "A.G.A",
      "family": "Coombes",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "J",
      "family": "Adler",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "J",
      "family": "Holland",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "S.S",
      "family": "Davis",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB1",
      "unstructured": "R.G. Tice and D.R. Cowsar, Biodegradable controlled-release parenteral systems. Pharm. Tech. 8 (1984) 26\u201335."
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB2",
      "doi-asserted-by": "crossref",
      "unstructured": "R. Langer, New methods of drug delivery. Science 249 (1990) 1527\u20131533.",
      "DOI": "10.1126/science.2218494"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB3",
      "unstructured": "D.H. Lewis, Controlled release of bioactive agents from lactide/glycolide polymers. In: M. Chassin and R. Langer (Eds.), Biodegradable Polymers as Drug Delivery Systems, Marcel Dekker, New York, 1990, pp. 1\u201341."
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB4",
      "doi-asserted-by": "crossref",
      "unstructured": "W. Morris, M.C. Steinhoff and P.K. Russell, Potential of polymer microencapsulation technology for vaccine innovation. Vaccine 12 (1994) 5\u201311.",
      "DOI": "10.1016/0264-410X(94)90003-5"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB5",
      "doi-asserted-by": "crossref",
      "unstructured": "D.T. O'Hagan, Oral delivery of vaccines. Clin. Pharmacokinet. 22 (1992) 1\u201310.",
      "DOI": "10.2165/00003088-199222010-00001"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB6",
      "doi-asserted-by": "crossref",
      "unstructured": "D.T. O'Hagan, H. Jeffery and S.S. Davis, Long term antibody response in mice following subcutaneous immunization with ovalbumin entrapped in biodegradable microparticles. Vaccine 11 (1993) 965\u2013969.",
      "DOI": "10.1016/0264-410X(93)90387-D"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB7",
      "doi-asserted-by": "crossref",
      "unstructured": "J.H. Eldridge, C.J. Hammond, J.A. Meulbroek, J.K. Staas, R.M. Gilley and T.R. Tice, Controlled vaccine release in the gut-associated lymphoid tissues. 1. Orally administered biodegradable microparticles target the Peyer's patches. J. Control. Release 11 (1990) 205\u2013214.",
      "DOI": "10.1016/0168-3659(90)90133-E"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB8",
      "doi-asserted-by": "crossref",
      "unstructured": "J. P. McGee, J. Mestecky, M.T. Dertzbaugh, J.H. Eldridge, M. Hirasawa and H. Kiyono, The mucosal immune systems: from fundamental concepts to vaccine development. Vaccine 10 (1992) 75\u201387.",
      "DOI": "10.1016/0264-410X(92)90021-B"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB9",
      "doi-asserted-by": "crossref",
      "unstructured": "D.T. O'Hagan, J.P. McGee, M. Lindblad and J. Holmgren, Cholera toxin B subunit (CTB) entrapped in microparticles shows comparable immunogenicity to CTB mixed with whole cholera toxin following oral immunization. Int. J. Pharm. 119 (1995) 251\u2013255.",
      "DOI": "10.1016/0378-5173(95)00046-L"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB10",
      "doi-asserted-by": "crossref",
      "unstructured": "T. Uchida and S.H. Goto, Oral delivery of poly(lactide-co-glycolide) microspheres containing ovalbumin as vaccine formulation: particle size study. Biol. Pharm. Bull. 17 (1994) 1272\u20131276.",
      "DOI": "10.1248/bpb.17.1272"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB11",
      "doi-asserted-by": "crossref",
      "unstructured": "P.U. Jani, A.T. Florence and D.E. McCarthy, Further histological evidence of the gasterointestinal absorption of polystyrene nanospheres in rat. Int. J. Pharm. 84 (1992) 245\u2013252.",
      "DOI": "10.1016/0378-5173(92)90162-U"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB12",
      "doi-asserted-by": "crossref",
      "unstructured": "P.G. Jenkins, K.A. Howard, N.W. Blackhall, N.W. Thomas, S.S. Davis and D.T. O'Hagan, Microparticulate absorption from the rat intestine. J. Control. Release 29 (1994) 339\u2013350.",
      "DOI": "10.1016/0168-3659(94)90079-5"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB13",
      "doi-asserted-by": "crossref",
      "unstructured": "R. Jalil and J.R. Nixon, Biodegradable poly(lactic acid) and poly(lactide-co-glycolide) microcapsules: problems associated with preparative techniques and release properties. J. Microencapsul. 7 (1990) 297\u2013325.",
      "DOI": "10.3109/02652049009021842"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB14",
      "doi-asserted-by": "crossref",
      "unstructured": "R. Arshady, Preparation of biodegradable microparticles and microcapsules. 2. Polylactide and related polyesters. J. Control. Release 17 (1991) 1\u201322.",
      "DOI": "10.1016/0168-3659(91)90126-X"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB15",
      "doi-asserted-by": "crossref",
      "unstructured": "Y. Ogawa, M. Yamomoto, H. Okada, T.T. Yashiko and T. Shimamoto, A new technique to efficiently entrap Leuprolide acetate into microcapsules of copoly lactic/glycolic acid. Chem. Pharm. Bull. 36 (1988) 1095\u20131103.",
      "DOI": "10.1248/cpb.36.1095"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB16",
      "unstructured": "M.N. Vrancken and D.A. Claeys, U.S. Patent 3526906, 1970."
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB17",
      "doi-asserted-by": "crossref",
      "unstructured": "H. Jeffery, S.S. Davis and D.T. O'Hagan, The preparation and characterisation of poly(lactide-co-glycolide) microparticles. II. The entrapment of a model protein using a (water-in oil-in water) emulsion solvent evaporation technique. Pharm. Res. 10 (1993) 362\u2013368.",
      "DOI": "10.1023/A:1018980020506"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB18",
      "doi-asserted-by": "crossref",
      "unstructured": "S. Cohen, T. Yoshioka, M. Lucarelli, H.L. Hwang and R. Langer, Controlled delivery systems for protein based on poly(lactic/glycolic acid) microparticles. Pharm. Res. 8 (1991) 713\u2013720.",
      "DOI": "10.1023/A:1015841715384"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB19",
      "doi-asserted-by": "crossref",
      "unstructured": "M.J.B. Prieto, F. Delie, E. Fattal, A. Tartar, F. Puisieux, A. Gulik and P. Couvreur, Characterisation of V3BRU peptide-loaded small PLGA microparticles prepared by a (W1/O)W2 emulsion solvent evaporation method. Int. J. Pharm. 111 (1994) 137\u2013145.",
      "DOI": "10.1016/0378-5173(94)00104-9"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB20",
      "doi-asserted-by": "crossref",
      "unstructured": "C. Yan, J.H. Resau, J. Heweston, M. West, W.L. Rill and M. Kende, Characterisation and morphological analysis of protein loaded poly(lactide-co-glycolide) microparticles prepared by water-in-oil-in-water emulsion technique. J. Control. Release 32 (1994) 231\u2013241.",
      "DOI": "10.1016/0168-3659(94)90233-X"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB21",
      "doi-asserted-by": "crossref",
      "unstructured": "M.S. Hora, R.K. Rana, J.H. Nunberg, T.R. Tice and R.M. Gilley, Release of human serum albumin from poly(lactide-co-glycolide) microparticles. Pharm. Res. 7 (1990) 1190\u20131194.",
      "DOI": "10.1023/A:1015948829632"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB22",
      "unstructured": "B. Alberts, B. Dennis, L. Julian, M. Raff, K. Roberts and J.D. Watson, Molecular Biology of Cells, Garland Publishing, New York."
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB23",
      "doi-asserted-by": "crossref",
      "unstructured": "N. Nihant, C. Schugens, C. Grandfils, R. Jerome and P. Teyssie, Polylactide microparticles prepared by double emulsion/evaporation technique. I. Effect of primary emulsion stability. Pharm. Res. 11 (1994) 1479\u20131484.",
      "DOI": "10.1023/A:1018912426983"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB24",
      "doi-asserted-by": "crossref",
      "unstructured": "G. Crotts and T.G. Park, Preparation of porous and nonporous biodegradable polymeric hollow microspheres. J. Control. Release 35 (1995) 91\u2013105.",
      "DOI": "10.1016/0168-3659(95)00010-6"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB25",
      "doi-asserted-by": "crossref",
      "unstructured": "H. K. Sah, R. Toddywala and Y.W. Chien, The influence of biodegradable microcapsules formulation on the controlled release of a protein. J. Control. Release 30 (1994) 201\u2013211.",
      "DOI": "10.1016/0168-3659(94)90026-4"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB26",
      "doi-asserted-by": "crossref",
      "unstructured": "H.T. Wang, E. Schmitt, D.R. Flanagan and R.J. Linhardt, Influence of formulation methods on the in vivo controlled release of protein from poly(ester) microparticles. J. Control. Release 17 (1991) 23\u201332.",
      "DOI": "10.1016/0168-3659(91)90127-Y"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB27",
      "doi-asserted-by": "crossref",
      "unstructured": "A.G.A. Coombes, E.C. Lavelle, P.G. Jenkins and S.S. Davis, Surface dose polymeric microparticle-based vaccines: the influence of formulation conditions on the magnitude and duration of the immune response to a protein antigen. Vaccine (1996) in press.",
      "DOI": "10.1016/S0264-410X(96)00077-1"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB28",
      "unstructured": "L. Tang and J.W. Eaton, Mechanism of acute inflammatory response to biomaterials. Cells Mater. 4 (1994) 429\u2013436."
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB29",
      "doi-asserted-by": "crossref",
      "unstructured": "R. Arshady, Microparticles and microcapsules. A survey of manufacturing techniques. Part III. Solvent evaporation. Polym. Eng. Sci. 30 (1990) 915\u2013921.",
      "DOI": "10.1002/pen.760301506"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB30",
      "doi-asserted-by": "crossref",
      "unstructured": "R. Bodmeier and J.W. McGinity, Solvent selection in the preparation of poly(dl-lactide) microparticles prepared by the solvent evaporation method. Int. J. Pharm. 43 (1988) 179\u2013186.",
      "DOI": "10.1016/0378-5173(88)90073-7"
    },
    {
      "key": "10.1016/S0168-3659(96)01475-7_BIB31",
      "doi-asserted-by": "crossref",
      "unstructured": "P.D. Scholes, A.G.A. Coombes, L. Illum, S.S. Davis and M.C. Davies, The preparation of sub-150 nm poly(lactide-co-glycolide) microparticles for site specific drug delivery. J. Control. Release 25 (1993) 145\u2013153.",
      "DOI": "10.1016/0168-3659(93)90103-C"
    }
  ],
  "container-title": "Journal of Controlled Release",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0168365996014757?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0168365996014757?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2019,
        4,
        26
      ]
    ],
    "date-time": "2019-04-26T05:00:15Z",
    "timestamp": 1556254815000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0168365996014757"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1997,
        1
      ]
    ]
  },
  "references-count": 31,
  "journal-issue": {
    "issue": "1",
    "published-print": {
      "date-parts": [
        [
          1997,
          1
        ]
      ]
    }
  },
  "alternative-id": [
    "S0168365996014757"
  ],
  "URL": "http://dx.doi.org/10.1016/S0168-3659(96)01475-7",
  "relation": {},
  "ISSN": [
    "0168-3659"
  ],
  "subject": [],
  "container-title-short": "Journal of Controlled Release",
  "published": {
    "date-parts": [
      [
        1997,
        1
      ]
    ]
  }
}