DOI: 10.1016/s0168-3659(01)00407-2. Chitosan-based nanoparticles for topical genetic immunization

Chitosan-based nanoparticles for topical genetic immunization

10.1016/s0168-3659(01)00407-2

Crossref journal-article

Elsevier BV

Journal of Controlled Release (78)

Bibliography

Cui, Z., & Mumper, R. J. (2001). Chitosan-based nanoparticles for topical genetic immunization. Journal of Controlled Release, 75(3), 409â419.

Authors 2

Zhengrong Cui (first)
Russell J Mumper (additional)

References 30 Referenced 204

{'key': '10.1016/S0168-3659(01)00407-2_BIB1', 'first-page': '1', 'article-title': 'DNA vaccines: a new era in vaccinology', 'volume': '772', 'author': 'Liu', 'year': '1995', 'journal-title': 'Ann. NY Acad. Sci.'} / Ann. NY Acad. Sci. / DNA vaccines: a new era in vaccinology by Liu (1995)
10.1016/S0952-7915(96)80042-2 / Curr. Opin. Immunol. / DNA vaccines by Ulmer (1996)
{'key': '10.1016/S0168-3659(01)00407-2_BIB3', 'series-title': 'New Generation Vaccines', 'author': 'Levine', 'year': '1997'} / New Generation Vaccines by Levine (1997)
R.J. Mumper, H.C. Ledebur Jr., Dendritic cell delivery of plasmid DNA: application for controlled nucleic acid-based vaccines, in: J.M. Walker (Ed.), Molecular Biology and Biotechnology, Humana Press, Inc., Totowa, New Jersey 2001. (10.1385/MB:19:1:079)
10.1046/j.1365-2567.1996.d01-718.x / Immunology / Generation of MHC class I-restricted cytotoxic T lymphocytes by expression of a viral protein in muscle cells: antigen presentation by non-muscle cells by Ulmer (1996)
10.1084/jem.184.4.1555 / J. Exp. Med. / Gene vaccination with naked plasmid DNA: mechanism of CTL priming by Corr (1996)
10.1126/science.7513904 / Science / Role of bone marrow derived cells in presenting MHC class I-restricted tumor antigens by Huang (1994)
10.1073/pnas.93.16.8578 / Proc. Natl. Acad. Sci. USA / Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells by Doe (1996)
10.4049/jimmunol.163.9.4721 / J. Immunol. / In vivo priming by DNA injection occurs predominantly by antigen transfer by Corr (1999)
10.4049/jimmunol.158.10.4529 / J. Immunol. / Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations by Torres (1997)
{'key': '10.1016/S0168-3659(01)00407-2_BIB11', 'first-page': '151', 'article-title': 'Enhanced immune response to an intradermally delivered DNA vaccine expressing a secreted form of BHV-1 gD', 'volume': '6', 'author': 'Braun', 'year': '1998', 'journal-title': 'Vaccine Res.'} / Vaccine Res. / Enhanced immune response to an intradermally delivered DNA vaccine expressing a secreted form of BHV-1 gD by Braun (1998)
10.1099/0022-1317-78-9-2139 / J. Gen. Virol. / Protection of pigs against Aujeszky’s disease by DNA vaccination by Gerdts (1997)
10.1016/S0165-2427(98)00186-X / Vet. Immunol. Immunopathol. / Effect of vaccination route and composition of DNA vaccine on the induction of protective immunity against pseudorabies infection in pigs by Van Rooij (1998)
10.1099/0022-1317-79-4-831 / J. Gen. Virol. / Intradermal immunization with a bovine herpesvius-1 DNA vaccine induces protective immunity in cattle by van Drunen Little-van den Hurk (1998)
10.1038/356152a0 / Nature / Genetic immunization is a simple method for eliciting an immune response by Tang (1992)
10.1073/pnas.90.24.11478 / Proc. Natl. Acad. Sci. USA / DNA vaccines: protective immunizations by parental, mucosal and gene-gun inoculations by Fynan (1993)
10.1016/S0264-410X(97)00202-8 / Vaccine / Intradermal DNA immunization of mice against influenza A virus using the novel Powderject system by Degano (1998)
10.1016/0264-410X(95)00069-D / Vaccine / Gene gun-based nucleic acid immunization: elicitation of humoral and cytotoxic T lymphocyte responses following epidermal delivery of nanogram quantities of DNA by Pertmer (1995)
10.1016/S0264-410X(99)00432-6 / Vaccine / Advantage of gene gun-mediated over intramuscular inoculation of plasmid DNA vaccine in reproducible induction of specific immune responses by Yoshida (2000)
10.1016/S0264-410X(98)00488-5 / Vaccine / DNA-based non-invasive vaccination onto the skin by Shi (1999)
10.1038/12856 / Nat. Biotechnol. / Immunization via hair follicles by topical application of naked DNA to normal skin by Fan (1999)
10.1038/41917 / Nature / Vaccination onto bare skin by Tang (1997)
10.1016/S0168-3659(98)00097-2 / J. Controlled Release / Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery by MacLaughlin (1998)
10.1038/7385 / Nat. Med. / Oral gene delivery with chitosan-pDNA nanoparticles generates immunologic protection in a murine model of peanut allergy by Roy (1999)
{'key': '10.1016/S0168-3659(01)00407-2_BIB25', 'first-page': '649', 'article-title': 'Evaluation of highly purified chitosan as a potential gene delivery vector', 'volume': '24', 'author': 'Richardson', 'year': '1997', 'journal-title': 'Proc. Int. Symp. Controlled Release Bioactive Mater.'} / Proc. Int. Symp. Controlled Release Bioactive Mater. / Evaluation of highly purified chitosan as a potential gene delivery vector by Richardson (1997)
10.1023/A:1011981000671 / Pharm. Res. / Chitosan-based vector/DNA complexes for gene delivery: biophysical characteristics and transfection ability by Erbacher (1998)
10.1073/pnas.97.2.811 / Proc. Natl. Acad. Sci. USA / Cationic microparticles: a potent delivery system for DNA vaccines by Singh (2000)
Z. Cui, R.J. Mumper, Dendritic cell-targeted genetic vaccines engineered from novel microemulsion precursors, in: Proceeding of the American Society of Gene Therapy, 4th Annual Meeting, Seattle, Washington, May 3–June 3, 2001 (abstract accepted) Mol. Therapy 3(5) (2001) S352.
10.1016/S0264-410X(98)00242-4 / Vaccine / Intradermal DNA immunization by using jet-injectors in mice and monkeys by Haensler (1999)
10.1073/pnas.90.24.11478 / Proc. Natl. Acad. Sci. USA / DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations by Fynan (1993)

Dates

Type	When
Created	22 years, 10 months ago (Oct. 31, 2002, 2:09 p.m.)
Deposited	2 years, 4 months ago (April 10, 2023, 6 a.m.)
Indexed	5 days, 22 hours ago (Aug. 31, 2025, 6:08 a.m.)
Issued	24 years, 1 month ago (Aug. 1, 2001)
Published	24 years, 1 month ago (Aug. 1, 2001)
Published Print	24 years, 1 month ago (Aug. 1, 2001)

Funders 0

None

BibTeX

@article{Cui_2001, title={Chitosan-based nanoparticles for topical genetic immunization}, volume={75}, ISSN={0168-3659}, url={http://dx.doi.org/10.1016/s0168-3659(01)00407-2}, DOI={10.1016/s0168-3659(01)00407-2}, number={3}, journal={Journal of Controlled Release}, publisher={Elsevier BV}, author={Cui, Zhengrong and Mumper, Russell J}, year={2001}, month=aug, pages={409–419} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        31
      ]
    ],
    "date-time": "2025-08-31T10:08:02Z",
    "timestamp": 1756634882950
  },
  "reference-count": 30,
  "publisher": "Elsevier BV",
  "issue": "3",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2001,
            8,
            1
          ]
        ],
        "date-time": "2001-08-01T00:00:00Z",
        "timestamp": 996624000000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        2001,
        8
      ]
    ]
  },
  "DOI": "10.1016/s0168-3659(01)00407-2",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2002,
        10,
        31
      ]
    ],
    "date-time": "2002-10-31T19:09:39Z",
    "timestamp": 1036091379000
  },
  "page": "409-419",
  "source": "Crossref",
  "is-referenced-by-count": 204,
  "title": "Chitosan-based nanoparticles for topical genetic immunization",
  "prefix": "10.1016",
  "volume": "75",
  "author": [
    {
      "given": "Zhengrong",
      "family": "Cui",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Russell J",
      "family": "Mumper",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB1",
      "first-page": "1",
      "article-title": "DNA vaccines: a new era in vaccinology",
      "volume": "772",
      "author": "Liu",
      "year": "1995",
      "journal-title": "Ann. NY Acad. Sci."
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB2",
      "doi-asserted-by": "crossref",
      "first-page": "531",
      "DOI": "10.1016/S0952-7915(96)80042-2",
      "article-title": "DNA vaccines",
      "volume": "8",
      "author": "Ulmer",
      "year": "1996",
      "journal-title": "Curr. Opin. Immunol."
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB3",
      "series-title": "New Generation Vaccines",
      "author": "Levine",
      "year": "1997"
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB4",
      "doi-asserted-by": "crossref",
      "unstructured": "R.J. Mumper, H.C. Ledebur Jr., Dendritic cell delivery of plasmid DNA: application for controlled nucleic acid-based vaccines, in: J.M. Walker (Ed.), Molecular Biology and Biotechnology, Humana Press, Inc., Totowa, New Jersey 2001.",
      "DOI": "10.1385/MB:19:1:079"
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB5",
      "doi-asserted-by": "crossref",
      "first-page": "59",
      "DOI": "10.1046/j.1365-2567.1996.d01-718.x",
      "article-title": "Generation of MHC class I-restricted cytotoxic T lymphocytes by expression of a viral protein in muscle cells: antigen presentation by non-muscle cells",
      "volume": "89",
      "author": "Ulmer",
      "year": "1996",
      "journal-title": "Immunology"
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB6",
      "doi-asserted-by": "crossref",
      "first-page": "1555",
      "DOI": "10.1084/jem.184.4.1555",
      "article-title": "Gene vaccination with naked plasmid DNA: mechanism of CTL priming",
      "volume": "184",
      "author": "Corr",
      "year": "1996",
      "journal-title": "J. Exp. Med."
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB7",
      "doi-asserted-by": "crossref",
      "first-page": "961",
      "DOI": "10.1126/science.7513904",
      "article-title": "Role of bone marrow derived cells in presenting MHC class I-restricted tumor antigens",
      "volume": "264",
      "author": "Huang",
      "year": "1994",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB8",
      "doi-asserted-by": "crossref",
      "first-page": "8578",
      "DOI": "10.1073/pnas.93.16.8578",
      "article-title": "Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells",
      "volume": "93",
      "author": "Doe",
      "year": "1996",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB9",
      "doi-asserted-by": "crossref",
      "first-page": "4721",
      "DOI": "10.4049/jimmunol.163.9.4721",
      "article-title": "In vivo priming by DNA injection occurs predominantly by antigen transfer",
      "volume": "163",
      "author": "Corr",
      "year": "1999",
      "journal-title": "J. Immunol."
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB10",
      "doi-asserted-by": "crossref",
      "first-page": "4529",
      "DOI": "10.4049/jimmunol.158.10.4529",
      "article-title": "Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations",
      "volume": "158",
      "author": "Torres",
      "year": "1997",
      "journal-title": "J. Immunol."
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB11",
      "first-page": "151",
      "article-title": "Enhanced immune response to an intradermally delivered DNA vaccine expressing a secreted form of BHV-1 gD",
      "volume": "6",
      "author": "Braun",
      "year": "1998",
      "journal-title": "Vaccine Res."
    },
    {
      "issue": "Pt 9",
      "key": "10.1016/S0168-3659(01)00407-2_BIB12",
      "doi-asserted-by": "crossref",
      "first-page": "2139",
      "DOI": "10.1099/0022-1317-78-9-2139",
      "article-title": "Protection of pigs against Aujeszky\u2019s disease by DNA vaccination",
      "volume": "78",
      "author": "Gerdts",
      "year": "1997",
      "journal-title": "J. Gen. Virol."
    },
    {
      "issue": "2",
      "key": "10.1016/S0168-3659(01)00407-2_BIB13",
      "doi-asserted-by": "crossref",
      "first-page": "113",
      "DOI": "10.1016/S0165-2427(98)00186-X",
      "article-title": "Effect of vaccination route and composition of DNA vaccine on the induction of protective immunity against pseudorabies infection in pigs",
      "volume": "66",
      "author": "Van Rooij",
      "year": "1998",
      "journal-title": "Vet. Immunol. Immunopathol."
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB14",
      "doi-asserted-by": "crossref",
      "first-page": "831",
      "DOI": "10.1099/0022-1317-79-4-831",
      "article-title": "Intradermal immunization with a bovine herpesvius-1 DNA vaccine induces protective immunity in cattle",
      "volume": "79",
      "author": "van Drunen Little-van den Hurk",
      "year": "1998",
      "journal-title": "J. Gen. Virol."
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB15",
      "doi-asserted-by": "crossref",
      "first-page": "152",
      "DOI": "10.1038/356152a0",
      "article-title": "Genetic immunization is a simple method for eliciting an immune response",
      "volume": "356",
      "author": "Tang",
      "year": "1992",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB16",
      "doi-asserted-by": "crossref",
      "first-page": "11478",
      "DOI": "10.1073/pnas.90.24.11478",
      "article-title": "DNA vaccines: protective immunizations by parental, mucosal and gene-gun inoculations",
      "volume": "90",
      "author": "Fynan",
      "year": "1993",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB17",
      "doi-asserted-by": "crossref",
      "first-page": "394",
      "DOI": "10.1016/S0264-410X(97)00202-8",
      "article-title": "Intradermal DNA immunization of mice against influenza A virus using the novel Powderject system",
      "volume": "16",
      "author": "Degano",
      "year": "1998",
      "journal-title": "Vaccine"
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "1427",
      "DOI": "10.1016/0264-410X(95)00069-D",
      "article-title": "Gene gun-based nucleic acid immunization: elicitation of humoral and cytotoxic T lymphocyte responses following epidermal delivery of nanogram quantities of DNA",
      "volume": "13",
      "author": "Pertmer",
      "year": "1995",
      "journal-title": "Vaccine"
    },
    {
      "issue": "17",
      "key": "10.1016/S0168-3659(01)00407-2_BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "1725",
      "DOI": "10.1016/S0264-410X(99)00432-6",
      "article-title": "Advantage of gene gun-mediated over intramuscular inoculation of plasmid DNA vaccine in reproducible induction of specific immune responses",
      "volume": "18",
      "author": "Yoshida",
      "year": "2000",
      "journal-title": "Vaccine"
    },
    {
      "issue": "17",
      "key": "10.1016/S0168-3659(01)00407-2_BIB20",
      "doi-asserted-by": "crossref",
      "first-page": "2136",
      "DOI": "10.1016/S0264-410X(98)00488-5",
      "article-title": "DNA-based non-invasive vaccination onto the skin",
      "volume": "17",
      "author": "Shi",
      "year": "1999",
      "journal-title": "Vaccine"
    },
    {
      "issue": "9",
      "key": "10.1016/S0168-3659(01)00407-2_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "870",
      "DOI": "10.1038/12856",
      "article-title": "Immunization via hair follicles by topical application of naked DNA to normal skin",
      "volume": "17",
      "author": "Fan",
      "year": "1999",
      "journal-title": "Nat. Biotechnol."
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "729",
      "DOI": "10.1038/41917",
      "article-title": "Vaccination onto bare skin",
      "volume": "388",
      "author": "Tang",
      "year": "1997",
      "journal-title": "Nature"
    },
    {
      "issue": "1\u20133",
      "key": "10.1016/S0168-3659(01)00407-2_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "259",
      "DOI": "10.1016/S0168-3659(98)00097-2",
      "article-title": "Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery",
      "volume": "56",
      "author": "MacLaughlin",
      "year": "1998",
      "journal-title": "J. Controlled Release"
    },
    {
      "issue": "4",
      "key": "10.1016/S0168-3659(01)00407-2_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "387",
      "DOI": "10.1038/7385",
      "article-title": "Oral gene delivery with chitosan-pDNA nanoparticles generates immunologic protection in a murine model of peanut allergy",
      "volume": "5",
      "author": "Roy",
      "year": "1999",
      "journal-title": "Nat. Med."
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB25",
      "first-page": "649",
      "article-title": "Evaluation of highly purified chitosan as a potential gene delivery vector",
      "volume": "24",
      "author": "Richardson",
      "year": "1997",
      "journal-title": "Proc. Int. Symp. Controlled Release Bioactive Mater."
    },
    {
      "issue": "9",
      "key": "10.1016/S0168-3659(01)00407-2_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "1332",
      "DOI": "10.1023/A:1011981000671",
      "article-title": "Chitosan-based vector/DNA complexes for gene delivery: biophysical characteristics and transfection ability",
      "volume": "15",
      "author": "Erbacher",
      "year": "1998",
      "journal-title": "Pharm. Res."
    },
    {
      "issue": "2",
      "key": "10.1016/S0168-3659(01)00407-2_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "811",
      "DOI": "10.1073/pnas.97.2.811",
      "article-title": "Cationic microparticles: a potent delivery system for DNA vaccines",
      "volume": "97",
      "author": "Singh",
      "year": "2000",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB28",
      "unstructured": "Z. Cui, R.J. Mumper, Dendritic cell-targeted genetic vaccines engineered from novel microemulsion precursors, in: Proceeding of the American Society of Gene Therapy, 4th Annual Meeting, Seattle, Washington, May 3\u2013June 3, 2001 (abstract accepted) Mol. Therapy 3(5) (2001) S352."
    },
    {
      "issue": "17(7\u20138)",
      "key": "10.1016/S0168-3659(01)00407-2_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "628",
      "DOI": "10.1016/S0264-410X(98)00242-4",
      "article-title": "Intradermal DNA immunization by using jet-injectors in mice and monkeys",
      "volume": "26",
      "author": "Haensler",
      "year": "1999",
      "journal-title": "Vaccine"
    },
    {
      "key": "10.1016/S0168-3659(01)00407-2_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "11478",
      "DOI": "10.1073/pnas.90.24.11478",
      "article-title": "DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations",
      "volume": "90",
      "author": "Fynan",
      "year": "1993",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    }
  ],
  "container-title": "Journal of Controlled Release",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0168365901004072?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0168365901004072?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        4,
        10
      ]
    ],
    "date-time": "2023-04-10T10:00:56Z",
    "timestamp": 1681120856000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0168365901004072"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2001,
        8
      ]
    ]
  },
  "references-count": 30,
  "journal-issue": {
    "issue": "3",
    "published-print": {
      "date-parts": [
        [
          2001,
          8
        ]
      ]
    }
  },
  "alternative-id": [
    "S0168365901004072"
  ],
  "URL": "http://dx.doi.org/10.1016/S0168-3659(01)00407-2",
  "relation": {},
  "ISSN": [
    "0168-3659"
  ],
  "subject": [],
  "container-title-short": "Journal of Controlled Release",
  "published": {
    "date-parts": [
      [
        2001,
        8
      ]
    ]
  }
}