Crossref journal-article
Elsevier BV
Immunology Today (78)
Bibliography

Kruisbeek, A. M., Haks, M. C., Carleton, M., Wiest, D. L., Michie, A. M., & Zúñiga-Pflücker, J. C. (2000). Branching out to gain control: how the pre-TCR is linked to multiple functions. Immunology Today, 21(12), 637–644.

Authors 6
  1. Ada M Kruisbeek (first)
  2. Mariëlle C Haks (additional)
  3. Michael Carleton (additional)
  4. David L Wiest (additional)
  5. Alison M Michie (additional)
  6. Juan Carlos Zúñiga-Pflücker (additional)
References 80 Referenced 95
  1. 10.1006/smim.1998.0153 / Sem. Immunol. / Cell-fate decisions in early T cell development: regulation by cytokine receptors and the pre-TCR by Haks (1999)
  2. 10.1016/S0952-7915(98)80249-5 / Curr. Opin. Immunol. / In vivo roles of receptor tyrosine kinases and cytokine receptors in early thymocyte development by Di Santo (1998)
  3. 10.1016/S0952-7915(99)80024-7 / Curr. Opin. Immunol. / Pleiotropic changes controlled by the pre-T cell receptor by Von Boehmer (1999)
  4. 10.1016/S1074-7613(00)80520-8 / Immunity / In thymic selection, peptide diversity gives and takes away by Bevan (1997)
  5. 10.1111/j.1600-065X.1998.tb01241.x / Immunol. Rev. / Thymocyte selection: not by TCR alone by Amsen (1998)
  6. 10.1126/science.8430336 / Science / Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes by Shinkai (1993)
  7. 10.1016/1074-7613(94)90102-3 / Immunity / T cell receptor β chain gene rearrangement and selection during thymocyte development in adult mice by Dudley (1994)
  8. 10.1016/S1074-7613(00)80381-7 / Immunity / Essential role of the pre-T cell receptor in allelic exclusion of the T cell receptor β locus by Aifantis (1997)
  9. 10.4049/jimmunol.163.11.6053 / J. Immunol. / TCRα-chain repertoire in pTα-deficient mice is diverse and developmentally regulated: implications for pre-TCR functions and TCRA gene rearrangement by Mancini (1999)
  10. 10.1016/S1074-7613(00)80454-9 / Immunity / Redundant regulation of T cell differentiation and TCRα gene expression by the transcription factors LEF-1 and TCF-1 by Okamura (1998)
  11. 10.1016/S1074-7613(00)80071-0 / Immunity / A developmental switch from TCRδ enhancer to TCRα enhancer function during thymocyte maturation by Hernández-Munain (1999)
  12. 10.1093/intimm/9.10.1475 / Int. Immunol. / Pre-TCR signaling components trigger transcriptional activation of a rearranged TCRα gene locus and silencing of the pre-TCRα locus: implications for intrathymic differentiation by Koyasu (1997)
  13. 10.1016/S1074-7613(00)80662-7 / Immunity / On the role of the pre-T cell receptor in αβ versus γδ T lineage commitment by Aifantis (1998)
  14. 10.1084/jem.186.9.1461 / J. Exp. Med. / Subunit composition of pre-T cell receptor complexes expressed by primary thymocytes: CD3δ is physically associated but not functionally required by Berger (1997)
  15. 10.1016/0092-8674(93)80070-U / Cell / A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor β chain and a 33 kd glycoprotein by Groettrup (1993)
  16. 10.1126/science.7973703 / Science / Analysis and expression of a cloned pre-T cell receptor gene by Saint-Ruf (1994)
  17. 10.1038/375795a0 / Nature / Crucial role of the pre-T-cell receptor α gene in development of αβ but not γδ T cells by Fehling (1995)
  18. 10.1093/emboj/16.6.1360 / EMBO J. / CD3δ deficiency arrests development of the αβ but not the γδ T cell lineage by Dave (1997)
  19. 10.1002/j.1460-2075.1995.tb00146.x / EMBO J. / Altered T cell development in mice with a targeted mutation of the CD3-ε gene by Malissen (1995)
  20. 10.1093/emboj/17.7.1871 / EMBO J. / The CD3γ chain is essential for development of both the TCRαβ and TCRγδ lineages by Haks (1998)
  21. 10.1126/science.7688481 / Science / T cell development in mice that lack the ζ chain of the T cell antigen receptor complex by Love (1993)
  22. 10.1002/j.1460-2075.1993.tb06119.x / EMBO J. / T cell development in mice lacking the CD3-ζ/η gene by Malissen (1993)
  23. 10.1002/j.1460-2075.1993.tb06120.x / EMBO J. / Developmental and functional impairment of T cells in mice lacking CD3ζ chains by Ohno (1993)
  24. 10.1002/j.1460-2075.1993.tb06176.x / EMBO J. / Abnormal T cell development in CD3-ζ−/− mutant mice and identification of a novel T cell population in the intestine by Liu (1993)
  25. 10.1038/360225a0 / Nature / Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages by Mombaerts (1992)
  26. 10.1073/pnas.95.25.14909 / Proc. Natl. Acad. Sci. USA / Specific requirement for CD3α in T cell development by DeJarnette (1998)
  27. 10.1002/(SICI)1521-4141(199907)29:07<2187::AID-IMMU2187>3.0.CO;2-D / Eur. J. Immunol. / The connecting peptide domain of pTα dictates weak association of the pre-T cell receptor with the TCRζ subunit by Trop (1999)
  28. 10.4049/jimmunol.165.10.5566 / J. Immunol. / Competitive displacement of pTα by T cell receptor (TCR)-α during TCR assembly prevents surface coexpression of pre-TCR and αβ TCR by Trop (2000)
  29. 10.4049/jimmunol.154.11.5862 / J. Immunol. / Regulation of early T cell development by the engagement of TCR-β complex expressed on fetal thymocytes from TCR-β-transgenic scid mice by Takahama (1995)
  30. 10.1126/science.280.5365.905 / Science / Thymocyte development in the absence of pre-T cell receptor extracellular immunoglobulin domains by Irving (1998)
  31. {'key': '10.1016/S0167-5699(00)01744-8_BIB31', 'first-page': '2089', 'article-title': 'Oncogenic potential of a pre-T cell receptor lacking the TCRβ variable domain', 'volume': '12', 'author': 'Jacobs', 'year': '1996', 'journal-title': 'Oncogene'} / Oncogene / Oncogenic potential of a pre-T cell receptor lacking the TCRβ variable domain by Jacobs (1996)
  32. 10.1016/S1074-7613(00)80380-5 / Immunity / Exit of the pre-TCR from the ER/cis-Golgi is necessary for signaling differentiation, proliferation, and allelic exclusion in immature thymocytes by O'Shea (1997)
  33. 10.1016/S1074-7613(00)80446-X / Immunity / Restoration of thymopoiesis in pTα−/− mice by anti-CD3ε antibody treatment or with transgenes encoding activated Lck or tailless pTα by Fehling (1997)
  34. 10.1038/76877 / Nat. Immunol. / The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling by Dustin (2000)
  35. 10.1038/35020093 / Nature / Different initiation of pre-TCR and γδTCR signalling by Saint-Ruf (2000)
  36. 10.1038/357161a0 / Nature / Profound block in thymocyte development in mice lacking p56lck by Molina (1992)
  37. 10.1016/1074-7613(94)90077-9 / Immunity / An activated lck transgene promotes thymocyte development in RAG-1 mutant mice by Mombaerts (1994)
  38. 10.1016/S1074-7613(00)80084-9 / Immunity / Pre-TCR signaling and inactivation of p53 induces crucial cell survival pathways in pre-T cells by Haks (1999)
  39. 10.1016/S1074-7613(00)80499-9 / Immunity / αβ T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases by Van Oers (1996)
  40. 10.1016/S1074-7613(00)80498-7 / Immunity / Fyn can partially substitute for Lck in T lymphocyte development by Groves (1996)
  41. 10.1038/29802 / Nature / Csk controls antigen receptor-mediated development and selection of T-lineage cells by Schmedt (1998)
  42. 10.1016/0092-8674(93)90302-7 / Cell / Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice by Kishihara (1993)
  43. 10.1084/jem.183.4.1707 / J. Exp. Med. / CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and in B cell maturation by Byth (1996)
  44. 10.1073/pnas.94.18.9797 / Proc. Natl. Acad. Sci. USA / The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling by Cheng (1997)
  45. 10.4049/jimmunol.161.6.2888 / J. Immunol. / An improved retroviral gene transfer technique demonstrates inhibition of CD4−CD8− thymocyte development by kinase-inactive ZAP-70 by Sugawara (1998)
  46. 10.1126/science.281.5375.416 / Science / Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development by Clements (1998)
  47. 10.1016/S1074-7613(00)80032-1 / Immunity / Essential role of LAT in T cell development by Zhang (1999)
  48. 10.1016/S0092-8674(00)81422-1 / Cell / Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76 by Pivniouk (1998)
  49. 10.1073/pnas.93.10.4683 / Proc. Natl. Acad. Sci. USA / Activated Ras signals differentiation and expansion of CD4+8+ thymocytes by Swat (1996)
  50. 10.1016/S1074-7613(00)80519-1 / Immunity / Different functions of the GTPase Rho in prothymocytes and late pre-T cells by Galandrini (1997)
  51. 10.1084/jem.192.1.77 / J. Exp. Med. / The GTPase Rho controls a p53-dependent survival checkpoint during thymopoiesis by Costello (2000)
  52. 10.1038/374474a0 / Nature / Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+CD8+ thymocytes by Fischer (1995)
  53. 10.1016/S1074-7613(00)80367-2 / Immunity / A requirement for the Rho-family GTP exchange factor Vav in positive and negative selection of thymocytes by Turner (1997)
  54. 10.1038/374467a0 / Nature / Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav by Tarakhovsky (1995)
  55. 10.1038/374470a0 / Nature / Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene by Zhang (1995)
  56. 10.1016/S1074-7613(00)80070-9 / Immunity / Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors by Iritani (1999)
  57. 10.1016/S1074-7613(00)80053-9 / Immunity / Immature thymocytes employ distinct signaling pathways for allelic exclusion versus differentiation and expansion by Gärtner (1999)
  58. 10.1084/jem.190.11.1647 / J. Exp. Med. / Extracellular signal-regulated kinase (ERK) activation by the pre-T cell receptor in developing thymocytes in vivo by Michie (1999)
  59. 10.1093/intimm/10.8.1077 / Int. Immunol. / Analysis of the role of MKK-4/Sek-1 in T cell development and apoptosis by Alberola-Ila (1998)
  60. 10.1016/S0960-9822(99)80065-7 / Curr. Biol. / JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development by Sabapathy (1999)
  61. 10.1016/S1074-7613(00)80567-1 / Immunity / SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development by Swat (1998)
  62. 10.4049/jimmunol.163.6.3331 / J. Immunol. / A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during ab thymopoiesis by Barndt (1999)
  63. 10.1084/jem.190.8.1039 / J. Exp. Med. / Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros by Winandy (1999)
  64. 10.1084/jem.186.6.877 / J. Exp. Med. / Two distinct steps during thymocyte maturation from CD4−CD8− to CD4+CD8+ distinguished in the early growth response (Egr)-1 transgenic mice with a recombinase-activating gene-deficient background by Miyazaki (1997)
  65. 10.1016/S0092-8674(00)80571-1 / Cell / Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT by Crabtree (1999)
  66. 10.1084/jem.183.4.1923 / J. Exp. Med. / p53 prevents maturation to the CD4+CD8+ stage of thymocyte differentiation in the absence of T cell receptor rearrangement by Jiang (1996)
  67. 10.1101/gad.10.5.553 / Genes Dev. / p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes by Bogue (1996)
  68. 10.1016/S0092-8674(00)80289-5 / Cell / Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1−/− mice by Maraskovsky (1997)
  69. 10.1093/emboj/19.5.931 / EMBO J. / FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor by Newton (2000)
  70. 10.1084/jem.188.5.931 / J. Exp. Med. / p56lck signals for regulating thymocyte development can be distinguished by their dependency on Rho function by Henning (1998)
  71. 10.1084/jem.190.8.1093 / J. Exp. Med. / Allelic exclusion of the T cell receptor β locus requires the SH2 domain-containing leukocyte protein (SLP)-76 adaptor protein by Aifantis (1999)
  72. 10.1126/science.281.5375.413 / Science / Uncoupling of nonreceptor tyrosine kinases from PLC-γ1 in an SLP-76-deficient T cell by Yablonski (1998)
  73. 10.1093/emboj/18.7.1832 / EMBO J. / Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-γ1 and Ras activation by Williams (1999)
  74. 10.1038/35006090 / Nature / PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes by Sun (2000)
  75. 10.1073/pnas.90.23.11401 / Proc. Natl. Acad. Sci. USA / Restoration of early thymocyte differentiation in T-cell receptor β-chain-deficient mutant mice by transmembrane signaling through CD3ε by Levelt (1993)
  76. 10.1016/1074-7613(95)90091-8 / Immunity / Regulation of thymocyte development through CD3: functional dissociation between p56lck and CD3ζ in early thymic selection by Levelt (1995)
  77. 10.1016/0092-8674(92)90030-G / Cell / RAG-1 deficient mice have no mature B and T lymphocytes by Mombaerts (1992)
  78. 10.1016/0092-8674(92)90029-C / Cell / RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement by Shinkai (1992)
  79. 10.1002/eji.1830240423 / Eur. J. Immunol. / CD3 components at the surface of pro-T cells can mediate pre-T cell development in vivo by Jacobs (1994)
  80. 10.1093/intimm/6.7.995 / Int. Immunol. / CD3ε-mediated signals rescue the development of CD4+CD8+ thymocytes in RAG-2−/− mice in the absence of TCR β chain expression by Shinkai (1994)
Dates
Type When
Created 23 years, 1 month ago (July 25, 2002, 4:59 p.m.)
Deposited 2 years, 4 months ago (April 13, 2023, 9:55 a.m.)
Indexed 5 months ago (March 30, 2025, 4:47 a.m.)
Issued 24 years, 9 months ago (Dec. 1, 2000)
Published 24 years, 9 months ago (Dec. 1, 2000)
Published Print 24 years, 9 months ago (Dec. 1, 2000)
Funders 0

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@article{Kruisbeek_2000, title={Branching out to gain control: how the pre-TCR is linked to multiple functions}, volume={21}, ISSN={0167-5699}, url={http://dx.doi.org/10.1016/s0167-5699(00)01744-8}, DOI={10.1016/s0167-5699(00)01744-8}, number={12}, journal={Immunology Today}, publisher={Elsevier BV}, author={Kruisbeek, Ada M and Haks, Mariëlle C and Carleton, Michael and Wiest, David L and Michie, Alison M and Zúñiga-Pflücker, Juan Carlos}, year={2000}, month=dec, pages={637–644} }