DOI: 10.1016/s0166-4328(99)00037-6. Progressive and gender-dependent cognitive impairment in the APPSW transgenic mouse model for Alzheimer’s disease

Progressive and gender-dependent cognitive impairment in the APPSW transgenic mouse model for Alzheimer’s disease

10.1016/s0166-4328(99)00037-6

Crossref journal-article

Elsevier BV

Behavioural Brain Research (78)

Bibliography

King, D. L., Arendash, G. W., Crawford, F., Sterk, T., Menendez, J., & Mullan, M. J. (1999). Progressive and gender-dependent cognitive impairment in the APPSW transgenic mouse model for Alzheimerâs disease. Behavioural Brain Research, 103(2), 145â162.

Authors 6

David L King (first)
Gary W Arendash (additional)
Fiona Crawford (additional)
Troy Sterk (additional)
Julian Menendez (additional)
Michael J Mullan (additional)

References 32 Referenced 163

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10.1016/0197-4580(89)90045-6 / Neurobiol Aging / Selective improvement of aged rat short-term spatial memory by 3,4-diaminopyridine by Barnes (1989)
10.1016/0197-4580(90)90110-L / Neurobiol Aging / Acetyl-1-carnitine 2: effects on learning and memory performance of aged rats in simple and complex mazes by Barnes (1990)
10.1016/S0896-6273(00)80974-5 / Neuron / Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins by Borchelt (1997)
10.1007/s002130050327 / Psychopharmacology / Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies by Crawley (1997)
{'key': '10.1016/S0166-4328(99)00037-6_BIB6', 'first-page': '108', 'article-title': 'Proteolytical processing of mutated human amyloid precursor protein in transgenic mice', 'volume': '47', 'author': 'Czech', 'year': '1997', 'journal-title': 'Mol Neurobiol'} / Mol Neurobiol / Proteolytical processing of mutated human amyloid precursor protein in transgenic mice by Czech (1997)
10.1016/0006-8993(94)90243-7 / Brain Res / A behavioural analysis of rats with damage to the medial prefrontal cortex using the Morris water maze: evidence for behavioral flexibility, but not for impaired spatial navigation by de Bruin (1994)
10.1016/0197-4580(93)90096-T / Neurobiol Aging / Beta A4 deposits are constant in the brains of the oldest old: an immunocytochemical study of 20 French centenarians by DeLaere (1993)
10.1097/00001756-199611040-00080 / NeuroReport / Spatial learning deficit in mice expressing human 751-amino acid β-amyloid precursor protein by D’Hooge (1996)
{'key': '10.1016/S0166-4328(99)00037-6_BIB10', 'first-page': '307', 'article-title': 'Microglial response to amyloid plaques in APPSW transgenic mice', 'volume': '152', 'author': 'Frautschy', 'year': '1998', 'journal-title': 'Am J Pathol'} / Am J Pathol / Microglial response to amyloid plaques in APPSW transgenic mice by Frautschy (1998)
10.1038/373523a0 / Nature / Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein by Games (1995)
10.1016/S0166-2236(96)20020-7 / Trends Neurosci / Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype? by Gerlai (1996)
10.1073/pnas.92.10.4402 / Proc Natl Acad Sci USA / Early Alzheimer disease-like histopathology increases in frequency with age in mice transgenic for β-APP751 by Higgins (1995)
10.1038/nm0198-097 / Nat Med / Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes by Holcomb (1998)
10.1016/0896-6273(95)90107-8 / Neuron / Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins by Hsiao (1995)
10.1126/science.274.5284.99 / Science / Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice by Hsiao (1996)
10.1097/00005072-199709000-00002 / J Neuropathol Exp Neurol / APPSW transgenic mice develop age-related Aβ deposits and neuropil abnormalities, but no neuronal loss in CA1 by Irizarry (1997)
10.1523/JNEUROSCI.17-18-07053.1997 / J Neurosci / Aβ deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse by Irizarry (1997)
10.1037/h0027502 / J Comp Physiol Psychol / Differential effects of hippocampal lesions upon sequential tasks and maze learning by the rat by Jackson (1969)
10.1073/pnas.94.4.1550 / Proc Natl Acad Sci USA / Amyloid precursor protein processing and Aβ42 deposition in a transgenic mouse model of Alzheimer disease by Johnson-Wood (1997)
10.1016/S0166-2236(96)20022-0 / Trends Neurosci / Mice, gene targeting and behaviour: more than just genetic background by Lathe (1996)
10.1016/S0926-6410(97)00006-2 / Brain Res Cogn Brain Res / Blind rats are not profoundly impaired in the reference memory Morris water maze and cannot be clearly discriminated from rats with cognitive deficits in the cued platform task by Lindner (1997)
10.1016/0197-4580(95)02070-5 / Neurobiol Aging / Lack of β-amyloidosis in transgenic mice expressing low levels of familial Alzheimer’s disease missense mutations by Malherbe (1996)
10.1073/pnas.92.12.5341 / Proc Natl Acad Sci USA / Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human β-amyloid precursor protein by Moran (1995)
10.1038/ng0892-345 / Nat Genet / A pathogenic mutation for probable Alzheimer’s disease in the APP gene at the N-terminus of β-amyloid by Mullan (1992)
10.1038/387500a0 / Nature / Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein by Nalbantaglu (1997)
{'key': '10.1016/S0166-4328(99)00037-6_BIB27', 'first-page': '871', 'article-title': 'Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer’s disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo', 'volume': '152', 'author': 'Pappolla', 'year': '1998', 'journal-title': 'Am J Pathol'} / Am J Pathol / Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer’s disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo by Pappolla (1998)
Pompl, P. Adaptation of the circular platform spatial memory task for mice: use in detecting cognitive impairment in the APPSW transgenic mouse model for Alzheimer’s disease. J Neurosci Methods, 1998;87:87–95. (10.1016/S0165-0270(98)00169-1)
{'key': '10.1016/S0166-4328(99)00037-6_BIB29', 'first-page': '20', 'article-title': 'The PDAPP transgenic mouse as an animal model for Aβ-induced amyloidosis and neuropathology', 'volume': '2', 'author': 'Schenk', 'year': '1997', 'journal-title': 'Alzheimer’s Dis Rev'} / Alzheimer’s Dis Rev / The PDAPP transgenic mouse as an animal model for Aβ-induced amyloidosis and neuropathology by Schenk (1997)
10.1046/j.1471-4159.1998.70052212.x / J Neurochem / Amyloid-β deposition in Alzheimer transgenic mice is associated with oxidative stress by Smith (1998)
10.1073/pnas.94.24.13287 / Proc Natl Acad Sci USA / Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology by Sturchler-Pierrat (1997)
10.1097/00001756-199112000-00013 / NeuroReport / Transgenic mice for the amyloid precursor protein 695 isoform have impaired spatial memory by Yamaguchi (1991)

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 7:51 p.m.)
Deposited	5 years, 7 months ago (Jan. 29, 2020, 3:26 p.m.)
Indexed	1 day, 18 hours ago (Aug. 31, 2025, 6:24 a.m.)
Issued	26 years ago (Sept. 1, 1999)
Published	26 years ago (Sept. 1, 1999)
Published Print	26 years ago (Sept. 1, 1999)

Funders 0

None

BibTeX

@article{King_1999, title={Progressive and gender-dependent cognitive impairment in the APPSW transgenic mouse model for Alzheimer’s disease}, volume={103}, ISSN={0166-4328}, url={http://dx.doi.org/10.1016/s0166-4328(99)00037-6}, DOI={10.1016/s0166-4328(99)00037-6}, number={2}, journal={Behavioural Brain Research}, publisher={Elsevier BV}, author={King, David L and Arendash, Gary W and Crawford, Fiona and Sterk, Troy and Menendez, Julian and Mullan, Michael J}, year={1999}, month=sep, pages={145–162} }

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