DOI: 10.1016/s0140-6736(03)12602-5. Disrupted hepcidin regulation in HFE -associated haemochromatosis and the liver as a regulator of body iron homoeostasis

Disrupted hepcidin regulation in HFE -associated haemochromatosis and the liver as a regulator of body iron homoeostasis

10.1016/s0140-6736(03)12602-5

Crossref journal-article

Elsevier BV

The Lancet (78)

Bibliography

Bridle, K. R., Frazer, D. M., Wilkins, S. J., Dixon, J. L., Purdie, D. M., Crawford, D. H., Subramaniam, V. N., Powell, L. W., Anderson, G. J., & Ramm, G. A. (2003). Disrupted hepcidin regulation in HFE -associated haemochromatosis and the liver as a regulator of body iron homoeostasis. The Lancet, 361(9358), 669â673.

Authors 10

Kim R Bridle (first)
David M Frazer (additional)
Sarah J Wilkins (additional)
Jeanette L Dixon (additional)
David M Purdie (additional)
Darrell HG Crawford (additional)
V Nathan Subramaniam (additional)
Lawrie W Powell (additional)
Gregory J Anderson (additional)
Grant A Ramm (additional)

References 30 Referenced 474

10.1038/ng0896-399 / Nat Genet / A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis by Feder (1996)
10.1007/s004390050549 / Hum Genet / A candidate gene for hemochromatosis: frequency of the C282Y and H63D mutations by Jouanolle (1997)
10.1016/0016-5085(80)90592-2 / Gastroenterology / Hemochromatosis: 1980 update by Powell (1980)
10.1055/s-2008-1041772 / Semin Liver Dis / Genetic hemochromatosis by Bassett (1984)
10.1080/00325481.1994.11945914 / Postgrad Med / Hereditary hemochromatosis: detecting and correcting iron overload by Olynyk (1994)
10.1016/S0950-3536(05)80129-5 / Baillieres Clin Haematol / Clinical spectrum and management of haemochromatosis by Niederau (1994)
10.1073/pnas.96.4.1579 / Proc Natl Acad Sci USA / Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum by Waheed (1999)
{'key': '10.1016/S0140-6736(03)12602-5_bib8', 'first-page': '559', 'article-title': 'Regulation of intestinal iron transport', 'author': 'Anderson', 'year': '2002'} / Regulation of intestinal iron transport by Anderson (2002)
10.1074/jbc.M008923200 / J Biol Chem / A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload by Pigeon (2001)
10.1073/pnas.151179498 / Proc Natl Acad Sci USA / Vaulont S. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice by Nicolas (2001)
10.1053/gast.2002.35353 / Gastroenterology / Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats by Frazer (2002)
10.1073/pnas.072632499 / Proc Natl Acad Sci USA / Severe iron deficiency anemia in transgenic mice expressing liver hepcidin by Nicolas (2002)
10.1152/ajpgi.2001.281.4.G931 / Am J Physiol Gastrointest Liver Physiol / Cloning and gastrointestinal expression of rat hephaestin: relationship to other iron transport proteins by Frazer (2001)
10.1016/S1097-2765(00)80425-6 / Mol Cell / A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation by McKie (2000)
10.1074/jbc.M000713200 / J Biol Chem / A novel mammalian iron-regulated protein involved in intracellular iron metabolism by Abboud (2000)
10.1038/35001596 / Nature / Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter by Donovan (2000)
10.1038/90038 / Nat Genet / A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis by Njajou (2001)
10.1172/JCI200113468 / J Clin Invest / Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene by Montosi (2001)
10.1002/hep.1840060106 / Hepatology / Value of hepatic iron measurements in early hemochromatosis and determination of the critical iron level associated with fibrosis by Bassett (1986)
{'key': '10.1016/S0140-6736(03)12602-5_bib20', 'first-page': '9', 'article-title': 'A simple technique for measuring storage iron concentrations in formalinised liver samples', 'volume': '33', 'author': 'Torrence', 'year': '1968', 'journal-title': 'S Afr J Med Sci'} / S Afr J Med Sci / A simple technique for measuring storage iron concentrations in formalinised liver samples by Torrence (1968)
{'key': '10.1016/S0140-6736(03)12602-5_bib21', 'series-title': 'The advanced theory of statistics', 'author': 'Kendall', 'year': '1977'} / The advanced theory of statistics by Kendall (1977)
10.1046/j.1365-2141.2001.02949.x / Br J Haematol / HFE mutations, iron deficiency and overload in 10,500 blood donors by Jackson (2001)
10.1182/blood-2002-04-1260 / Blood / Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease by Weinstein (2002)
{'key': '10.1016/S0140-6736(03)12602-5_bib24', 'first-page': '194A', 'article-title': 'Hereditary hemochromatosis and liver transplantation: implications for patient survival, graft function and the pathogenesis of hereditary hemochromatosis', 'volume': '36', 'author': 'Crawford', 'year': '2002', 'journal-title': 'Hepatology'} / Hepatology / Hereditary hemochromatosis and liver transplantation: implications for patient survival, graft function and the pathogenesis of hereditary hemochromatosis by Crawford (2002)
10.1073/pnas.94.6.2534 / Proc Natl Acad Sci USA / Immunohistochemistry of HLA-H, the protein defective in patients with hereditary hemochromatosis, reveals unique pattern of expression in gastrointestinal tract by Parkkila (1997)
10.1074/jbc.M008922200 / J Biol Chem / Hepcidin, a urinary antimicrobial peptide synthesized in the liver by Park (2001)
{'key': '10.1016/S0140-6736(03)12602-5_bib27', 'first-page': '390', 'article-title': 'Regulation of intestinal iron absorption and mucosal iron kinetics in hereditary hemochromatosis', 'volume': '117', 'author': 'McLaren', 'year': '1991', 'journal-title': 'J Lab Clin Med'} / J Lab Clin Med / Regulation of intestinal iron absorption and mucosal iron kinetics in hereditary hemochromatosis by McLaren (1991)
10.1073/pnas.051630898 / Proc Natl Acad Sci USA / Mouse strain differences determine severity of iron accumulation in Hfe knockout model of hereditary hemochromatosis by Fleming (2001)
10.1053/gast.2002.31877 / Gastroenterology / Inactivation of the hemochromatosis gene differentially regulates duodenal expression of iron-related mRNAs between mouse strains by Dupic (2002)
10.1182/blood-2002-05-1565 / Blood / Increased hepatic iron in mice lacking classical MHC class I molecules by Cardoso (2002)

Dates

Type	When
Created	22 years, 5 months ago (March 25, 2003, 11:52 a.m.)
Deposited	5 years, 5 months ago (March 17, 2020, 3 p.m.)
Indexed	1 day, 17 hours ago (Sept. 3, 2025, 7:17 a.m.)
Issued	22 years, 7 months ago (Feb. 1, 2003)
Published	22 years, 7 months ago (Feb. 1, 2003)
Published Print	22 years, 7 months ago (Feb. 1, 2003)

Funders 0

None

BibTeX

@article{Bridle_2003, title={Disrupted hepcidin regulation in HFE -associated haemochromatosis and the liver as a regulator of body iron homoeostasis}, volume={361}, ISSN={0140-6736}, url={http://dx.doi.org/10.1016/s0140-6736(03)12602-5}, DOI={10.1016/s0140-6736(03)12602-5}, number={9358}, journal={The Lancet}, publisher={Elsevier BV}, author={Bridle, Kim R and Frazer, David M and Wilkins, Sarah J and Dixon, Jeanette L and Purdie, David M and Crawford, Darrell HG and Subramaniam, V Nathan and Powell, Lawrie W and Anderson, Gregory J and Ramm, Grant A}, year={2003}, month=feb, pages={669–673} }

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  "alternative-id": [
    "S0140673603126025"
  ],
  "URL": "http://dx.doi.org/10.1016/S0140-6736(03)12602-5",
  "relation": {},
  "ISSN": [
    "0140-6736"
  ],
  "subject": [],
  "container-title-short": "The Lancet",
  "published": {
    "date-parts": [
      [
        2003,
        2
      ]
    ]
  }
}