Crossref journal-article
Elsevier BV
Cell (78)
Bibliography

Chen, H.-K., Fernandez-Funez, P., Acevedo, S. F., Lam, Y. C., Kaytor, M. D., Fernandez, M. H., Aitken, A., Skoulakis, E. M. C., Orr, H. T., Botas, J., & Zoghbi, H. Y. (2003). Interaction of Akt-Phosphorylated Ataxin-1 with 14-3-3 Mediates Neurodegeneration in Spinocerebellar Ataxia Type 1. Cell, 113(4), 457–468.

Authors 11
  1. Hung-Kai Chen (first)
  2. Pedro Fernandez-Funez (additional)
  3. Summer F. Acevedo (additional)
  4. Yung C. Lam (additional)
  5. Michael D. Kaytor (additional)
  6. Michael H. Fernandez (additional)
  7. Alastair Aitken (additional)
  8. Efthimios M.C. Skoulakis (additional)
  9. Harry T. Orr (additional)
  10. Juan Botas (additional)
  11. Huda Y. Zoghbi (additional)
References 34 Referenced 332
  1. 10.1016/S0306-4522(01)00492-4 / Neuroscience / Immunolocalisation of 14–3-3 isoforms in normal and scrapie-infected murine brain by Baxter (2002)
  2. 10.1016/S0092-8674(02)01083-8 / Cell / PKB binding proteins. Getting in on the Akt by Brazil (2002)
  3. 10.1016/S0959-4388(00)00211-7 / Curr. Opin. Neurobiol. / Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway by Brunet (2001)
  4. 10.1083/jcb.200112059 / J. Cell Biol. / 14–3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport by Brunet (2002)
  5. 10.1126/science.296.5573.1655 / Science / The phosphoinositide 3-kinase pathway by Cantley (2002)
  6. 10.1073/pnas.101596998 / Proc. Natl. Acad. Sci. USA / Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway by Cho (2001)
  7. 10.1038/502 / Nat. Genet. / Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1 by Cummings (1998)
  8. 10.1016/S0896-6273(02)00780-8 / Neuron / Animal models of PD by Dawson (2002)
  9. 10.1073/pnas.94.9.4772 / Proc. Natl. Acad. Sci. USA / Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid- and human amylin-induced toxicity by Dore (1997)
  10. 10.1016/S0896-6273(03)00258-7 / Neuron / Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice by Emamian (2003)
  11. 10.1038/35040584 / Nature / Identification of genes that modify ataxin-1-induced neurodegeneration by Fernandez-Funez (2000)
  12. 10.1146/annurev.pharmtox.40.1.617 / Annu. Rev. Pharmacol. Toxicol. / 14–3-3 proteins by Fu (2000)
  13. 10.1074/jbc.M003738200 / J. Biol. Chem. / 14–3-3ζ is an effector of tau protein phosphorylation by Hashiguchi (2000)
  14. 10.1016/S1534-5807(02)00188-0 / Dev. Cell / The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt by Humbert (2002)
  15. 10.1016/S0092-8674(00)81688-8 / Cell / Signaling–2000 and beyond by Hunter (2000)
  16. 10.1126/science.8085159 / Science / Stimulatory effects of yeast and mammalian 14–3-3 proteins on the Raf protein kinase by Irie (1994)
  17. 10.1016/S0896-6273(02)00706-7 / Neuron / Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila by Jackson (2002)
  18. 10.1074/jbc.M011549200 / J. Biol. Chem. / The chaperone protein 14–3-3eta interacts with the nicotinic acetylcholine receptor alpha 4 subunit. Evidence for a dynamic role in subunit stabilization by Jeanclos (2001)
  19. 10.1093/jnen/61.3.245 / J. Neuropathol. Exp. Neurol. / 14–3-3 proteins in Lewy bodies in Parkinson disease and diffuse Lewy body disease brains by Kawamoto (2002)
  20. 10.1074/jbc.274.53.37507 / J. Biol. Chem. / Aberrant protein deposition and neurological disease by Kaytor (1999)
  21. 10.1016/0304-3940(96)12598-2 / Neurosci. Lett. / Neurofibrillary tangles of Alzheimer's disease brains contain 14–3-3 proteins by Layfield (1996)
  22. 10.1146/annurev.neuro.24.1.1121 / Annu. Rev. Neurosci. / Neurodegenerative tauopathies by Lee (2001)
  23. 10.1002/j.1460-2075.1996.tb01049.x / EMBO J. / The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth by Leevers (1996)
  24. 10.1093/emboj/20.1.27 / EMBO J. / Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice by Lucas (2001)
  25. 10.1093/hmg/10.14.1441 / Hum. Mol. Genet. / SCA17, a novel autosomal dominant cerebellar ataxia caused by an expanded polyglutamine in TATA-binding protein by Nakamura (2001)
  26. 10.1523/JNEUROSCI.19-14-05782.1999 / J. Neurosci. / α-Synuclein shares physical and functional homology with 14–3-3 proteins by Ostrerova (1999)
  27. 10.1074/jbc.R100059200 / J. Biol. Chem. / 14–3-3 proteins by Tzivion (2002)
  28. 10.1038/70293 / Nat. Cell Biol. / Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB by Verdu (1999)
  29. 10.1016/S0896-6273(02)00733-X / Neuron / A long CAG repeat in the mouse Sca1 locus replicates SCA1 features and reveals the impact of protein solubility on selective neurodegeneration by Watase (2002)
  30. 10.1074/jbc.M111704200 / J. Biol. Chem. / Signaling events in amyloid beta-peptide-induced neuronal death and insulin-like growth factor I protection by Wei (2002)
  31. 10.1038/nm0602-600 / Nat. Med. / Dopamine-dependent neurotoxicity of α-synuclein by Xu (2002)
  32. 10.1038/86737 / Nat. Biotechnol. / A motif-based profile scanning approach for genome-wide prediction of signaling pathways by Yaffe (2001)
  33. 10.1016/S0168-9525(02)02729-4 / Trends Genet. / Mouse and fly models of neurodegeneration by Zoghbi (2002)
  34. 10.1146/annurev.neuro.23.1.217 / Annu. Rev. Neurosci. / Glutamine repeats and neurodegeneration by Zoghbi (2000)
Dates
Type When
Created 21 years, 4 months ago (April 21, 2004, 1:15 a.m.)
Deposited 5 years, 4 months ago (April 1, 2020, 11:45 a.m.)
Indexed 4 months ago (April 28, 2025, 1:22 a.m.)
Issued 22 years, 3 months ago (May 1, 2003)
Published 22 years, 3 months ago (May 1, 2003)
Published Print 22 years, 3 months ago (May 1, 2003)
Funders 0

None

@article{Chen_2003, title={Interaction of Akt-Phosphorylated Ataxin-1 with 14-3-3 Mediates Neurodegeneration in Spinocerebellar Ataxia Type 1}, volume={113}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/s0092-8674(03)00349-0}, DOI={10.1016/s0092-8674(03)00349-0}, number={4}, journal={Cell}, publisher={Elsevier BV}, author={Chen, Hung-Kai and Fernandez-Funez, Pedro and Acevedo, Summer F. and Lam, Yung C. and Kaytor, Michael D. and Fernandez, Michael H. and Aitken, Alastair and Skoulakis, Efthimios M.C. and Orr, Harry T. and Botas, Juan and Zoghbi, Huda Y.}, year={2003}, month=may, pages={457–468} }