Crossref journal-article
Elsevier BV
Cell (78)
Bibliography

Collins, B. M., McCoy, A. J., Kent, H. M., Evans, P. R., & Owen, D. J. (2002). Molecular Architecture and Functional Model of the Endocytic AP2 Complex. Cell, 109(4), 523–535.

Authors 5
  1. Brett M. Collins (first)
  2. Airlie J. McCoy (additional)
  3. Helen M. Kent (additional)
  4. Philip R. Evans (additional)
  5. David J. Owen (additional)
References 60 Referenced 503
  1. 10.1107/S0907444995008754 / Acta Crystallogr. D / Methods used in the structure determination of bovine mitochondrial F1 ATPase by Abrahams (1996)
  2. 10.1016/S0021-9258(20)64342-3 / J. Biol. Chem. / Interaction of phosphoinositide cycle intermediates with the plasma membrane-associated clathrin assembly protein AP2 by Beck (1991)
  3. 10.1091/mbc.12.10.2907 / Mol. Biol. Cell / Adaptins—the final recount by Boehm (2001)
  4. 10.1002/j.1460-2075.1996.tb00965.x / EMBO J. / Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP2 complexes by Boll (1996)
  5. 10.1146/annurev.cellbio.17.1.517 / Annu. Rev. Cell. Dev. Biol. / Biological basket weaving by Brodsky (2001)
  6. 10.1016/S0021-9258(17)42343-X / J. Biol. Chem. / The intracellular tyrosine kinase domain of the epidermal growth factor receptor undergoes a conformational change upon autophosphorylation by Cadena (1994)
  7. 10.1002/j.1460-2075.1993.tb05865.x / EMBO J. / Adaptor self-aggregation, adaptor-receptor recognition and binding of the alpha-adaptin subunit to the plasma membrane contribute to recruitment of adaptor (AP2) components of clathrin-coated pits by Chang (1993)
  8. 10.1083/jcb.200108123 / J. Cell Biol. / Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin mediated endocytosis by Conner (2002)
  9. 10.1016/S0092-8674(00)81649-9 / Cell / Essential role of phosphoinositide metabolism in synaptic vesicle recycling by Cremona (1999)
  10. {'key': '10.1016/S0092-8674(02)00735-3_BIB10', 'series-title': 'Methods in Enzymology, Volume 472', 'article-title': 'Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods', 'author': 'de la Fortelle', 'year': '1997'} / Methods in Enzymology, Volume 472 / Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods by de la Fortelle (1997)
  11. 10.1038/nsb0497-269 / Nat. Struct. Biol. / Improved R-factors for diffraction data analysis in macromolecular crystallography by Diederichs (1997)
  12. 10.1083/jcb.200106089 / J. Cell Biol. / The actin-binding protein Hip1R associates with clathrin during early stages of endocytosis and promotes clathrin assembly in vitro by Engqvist-Goldstein (2001)
  13. 10.1074/jbc.M009516200 / J. Biol. Chem. / Binding of AP2 to sorting signals is modulated by AP2 phosphorylation by Fingerhut (2001)
  14. 10.1126/science.291.5506.1051 / Science / Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes by Ford (2001)
  15. 10.1083/jcb.146.4.755 / J. Cell Biol. / Phosphoinositide-AP-2 interactions required for targeting to plasma membrane clathrin-coated pits by Gaidarov (1999)
  16. 10.1074/jbc.271.34.20922 / J. Biol. Chem. / A functional phosphatidylinositol 3,4,5-trisphosphate/phosphoinositide binding domain in the clathrin adaptor AP2 alpha subunit—implications for the endocytic pathway by Gaidarov (1996)
  17. 10.1016/S1097-2765(01)00191-5 / Mol. Cell / The class II phosphoinositide 3-kinase C2alpha is activated by clathrin and regulates clathrin-mediated membrane trafficking by Gaidarov (2001)
  18. 10.1093/emboj/19.17.4577 / EMBO J. / Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells by Gillooly (2000)
  19. 10.1074/jbc.M101584200 / J. Biol. Chem. / A novel snare N-terminal domain revealed by the crystal structure of Sec22b by Gonzalez (2001)
  20. 10.1038/383447a0 / Nature / Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor by Goodman (1996)
  21. 10.1016/S0960-9822(00)00446-2 / Curr. Biol. / Direct interaction of the 170 kDa isoform of synaptojanin 1 with clathrin and with the clathrin adaptor AP-2 by Haffner (2000)
  22. 10.1083/jcb.107.3.877 / J. Cell Biol. / Deep-etch visualization of proteins involved in clathrin assembly by Heuser (1988)
  23. 10.1021/cr000225s / Chem. Rev. / Structural basis for control by phosphorylation by Johnson (2001)
  24. 10.1016/S0960-9822(98)00022-0 / Curr. Biol. / Phosphatidylinositol-4,5-bisphosphate is required for endocytic-coated vesicle formation by Jost (1998)
  25. 10.1016/0092-8674(79)90007-2 / Cell / Clathrin-coated vesicles by Keen (1979)
  26. 10.1146/annurev.cellbio.15.1.705 / Annu. Rev. Cell Dev. Biol. / Adaptors for clathrin-mediated traffic by Kirchhausen (1999)
  27. 10.1073/pnas.86.8.2612 / Proc. Natl. Acad. Sci. USA / Structural and functional division into two domains of the large (100–115kDa) chains of the clathrin associated protein complex AP2 by Kirchhausen (1989)
  28. 10.1016/S0960-9822(98)70296-9 / Curr. Biol. / The pleckstrin homology domain of oxysterol-binding protein recognises a determinant specific to Golgi membranes by Levine (1998)
  29. 10.1093/emboj/16.22.6646 / EMBO J. / The crystal structure of a phosphorylase kinase peptide substrate complex by Lowe (1997)
  30. 10.1021/bi00500a011 / Biochemistry / Stabilization of clathrin coats by the core of the clathrin-associated protein complex AP-2 by Matsui (1990)
  31. 10.1093/emboj/19.10.2193 / EMBO J. / mu1A-adaptin-deficient mice by Meyer (2000)
  32. 10.1016/S0896-6273(01)00467-6 / Neuron / Uncoating of clathrin-coated vesicles in presynaptic terminals. Roles for hsc70 and auxilin by Morgan (2001)
  33. 10.1107/S0907444996012255 / Acta Crystallogr. D / Refinement of macromolecular structures by the maximum-likelihood method by Murshudov (1997)
  34. 10.1093/emboj/18.9.2489 / EMBO J. / Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 bydominant-negative mutant mu2 subunit and its effects on endocytosis by Nesterov (1999)
  35. 10.1126/science.7569928 / Science / Interaction of tyrosine-based sorting signals with clathrin-associated proteins by Ohno (1995)
  36. 10.1016/S0960-9822(01)00240-8 / Curr. Biol. / Phosphorylation of threonine 156 of the mu2 subunit of the AP2 complex is essential for endocytosis in vitro and in vivo by Olusanya (2001)
  37. 10.1126/science.282.5392.1327 / Science / A structural explanation for the recognition of tyrosine-based endocytotic signals by Owen (1998)
  38. 10.1016/S0092-8674(00)80791-6 / Cell / A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain by Owen (1999)
  39. 10.1093/emboj/19.16.4216 / EMBO J. / The structure and function of the beta2-adaptin appendage domain by Owen (2000)
  40. 10.1034/j.1600-0854.2001.020205.x / Traffic / A third specificity-determining site in mu 2 adaptin for sequences upstream of Yxx Phi sorting motifs by Owen (2001)
  41. 10.1083/jcb.131.3.619 / J. Cell Biol. / Targeting signals and subunit interactions in coated vesicle adaptor complexes by Page (1995)
  42. 10.1042/bj2960409 / Biochem. J. / The 50 kDa protein subunit of assembly polypeptide (AP) AP-2 adaptor from clathrin-coated vesicles is phosphorylated on threonine-156 by AP-1 and a soluble AP50 kinase which co-purifies with the assembly polypeptides by Pauloin (1993)
  43. 10.1016/S0022-2836(75)80024-6 / J. Mol. Biol. / Coated vesicles from pig brain by Pearse (1975)
  44. 10.1083/jcb.200107140 / J. Cell Biol. / Assembly and function of AP3 complexes in cells expressing mutant subunits by Peden (2002)
  45. 10.1091/mbc.10.3.677 / Mol. Biol. Cell / Cluster of differentiation antigen 4 (CD4) endocytosis and adaptor complex binding require activation of the CD4 endocytosis signal by serine phosphorylation by Pitcher (1999)
  46. 10.1093/emboj/16.9.2240 / EMBO J. / Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes by Rapoport (1997)
  47. 10.1093/emboj/17.8.2148 / EMBO J. / Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site by Rapoport (1998)
  48. 10.1083/jcb.200111068 / J. Cell Biol. / Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals by Ricotta (2002)
  49. 10.1083/jcb.104.4.887 / J. Cell Biol. / 100-kD coated vesicle proteins by Robinson (1987)
  50. 10.1074/jbc.273.11.6005 / J. Biol. Chem. / Medium chains of adaptor complexes ap-1 and ap-2 recognize leucine-based sorting signals from the invariant chain by Rodionov (1998)
  51. 10.1083/jcb.132.4.565 / J. Cell Biol. / The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane by Rohrer (1996)
  52. 10.1016/S0955-0674(00)00240-4 / Curr. Opin. Cell Biol. / The role of phosphoinositides in membrane transport by Simonsen (2001)
  53. 10.1073/pnas.97.3.1096 / Proc. Natl. Acad. Sci. USA / Peptide-in-groove interactions link target proteins to the beta-propeller of clathrin by ter Haar (2000)
  54. 10.1126/science.1062950 / Science / An autoinhibitory mechanism for nonsyntaxin SNARE proteins revealed by the structure of Ykt6p by Tochio (2001)
  55. 10.1016/S0962-8924(96)20042-X / Trends Cell Biol. / Clathrin-associated adaptor proteins—putting it all together by Traub (1997)
  56. 10.1073/pnas.96.16.8907 / Proc. Natl. Acad. Sci. USA / Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly by Traub (1999)
  57. 10.1078/S0171-9335(04)70037-0 / Eur. J. Cell Biol. / Identification of the universal cofactor (auxilin 2) in clathrin coat dissociation by Umeda (2000)
  58. 10.1016/1074-7613(94)90071-X / Immunity / CTLA-4 can function as a negative regulator of T-cell activation by Walunas (1994)
  59. 10.1083/jcb.135.3.635 / J. Cell Biol. / In vivo phosphorylation of adaptors regulates their interaction with clathrin by Wilde (1996)
  60. 10.1002/jcb.240280108 / J. Cell. Biochem. / Limited proteolytic digestion of coated vesicle assembly polypeptides abolishes reassembly activity by Zaremba (1985)
Dates
Type When
Created 21 years, 4 months ago (April 17, 2004, 2:47 p.m.)
Deposited 2 years, 6 months ago (Jan. 25, 2023, 5:48 p.m.)
Indexed 1 week, 4 days ago (Aug. 12, 2025, 6:02 p.m.)
Issued 23 years, 3 months ago (May 1, 2002)
Published 23 years, 3 months ago (May 1, 2002)
Published Print 23 years, 3 months ago (May 1, 2002)
Funders 0

None

@article{Collins_2002, title={Molecular Architecture and Functional Model of the Endocytic AP2 Complex}, volume={109}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/s0092-8674(02)00735-3}, DOI={10.1016/s0092-8674(02)00735-3}, number={4}, journal={Cell}, publisher={Elsevier BV}, author={Collins, Brett M. and McCoy, Airlie J. and Kent, Helen M. and Evans, Philip R. and Owen, David J.}, year={2002}, month=may, pages={523–535} }