DOI: 10.1016/s0092-8674(01)00611-0. XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

10.1016/s0092-8674(01)00611-0

Crossref journal-article

Elsevier BV

Cell (78)

Bibliography

Yoshida, H., Matsui, T., Yamamoto, A., Okada, T., & Mori, K. (2001). XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor. Cell, 107(7), 881â891.

Authors 5

Hiderou Yoshida (first)
Toshie Matsui (additional)
Akira Yamamoto (additional)
Tetsuya Okada (additional)
Kazutoshi Mori (additional)

References 27 Referenced 3,385

10.1093/emboj/18.11.3119 / EMBO J. / Mechanism of nonspliceosomal mRNA splicing in the unfolded protein response pathway by Gonzalez (1999)
10.1091/mbc.10.11.3787 / Mol. Biol. Cell / Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress by Haze (1999)
10.1042/0264-6021:3550019 / Biochem. J. / Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response by Haze (2001)
10.1038/35055065 / Nat. Cell Biol. / Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress by Iwawaki (2001)
10.1101/gad.13.10.1211 / Genes Dev. / Stress signaling from the lumen of the endoplasmic reticulum by Kaufman (1999)
10.1074/jbc.273.3.1802 / J. Biol. Chem. / Unconventional splicing of HAC1/ERN4 mRNA required for the unfolded protein response by Kawahara (1998)
10.1126/science.2321018 / Science / A new member of the leucine zipper class of proteins that binds to the HLA DRα promoter by Liou (1990)
10.1016/S0092-8674(00)80855-7 / Cell / Tripartite management of unfolded proteins in the endoplasmic reticulum by Mori (2000)
10.1073/pnas.050010197 / Proc. Natl. Acad. Sci. USA / mRNA splicing-mediated C-terminal replacement of transcription factor Hac1p is required for efficient activation of the unfolded protein response by Mori (2000)
10.1016/S0092-8674(00)81667-0 / Cell / A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response by Niwa (1999)
10.1016/S0955-0674(00)00219-2 / Curr. Opin. Cell Biol. / Intracellular signaling from the endoplasmic reticulum to the nucleus by Patil (2001)
10.1101/gad.14.2.152 / Genes Dev. / An essential role in liver development for transcription factor XBP-1 by Reimold (2000)
10.1038/35085509 / Nature / Plasma cell differentiation requires the transcription factor XBP-1 by Reimold (2001)
10.1093/nar/27.6.1437 / Nucleic Acids Res. / The mammalian endoplasmic reticulum stress response element consists of an evolutionarily conserved tripartite structure and interacts with a novel stress inducible complex by Roy (1999)
10.1016/S0092-8674(01)00505-0 / Cell / Block of HAC1 mRNA translation by long range base pairing is released by cytoplasmic splicing upon induction of the unfolded protein response by Ruegsegger (2001)
{'key': '10.1016/S0092-8674(01)00611-0_BIB16', 'series-title': 'Molecular Cloning', 'author': 'Sambrook', 'year': '1989'} / Molecular Cloning by Sambrook (1989)
10.1101/gad.12.12.1812 / Genes Dev. / A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells by Tirasophon (1998)
10.1101/gad.839400 / Genes Dev. / The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response by Tirasophon (2000)
10.1242/jcs.113.21.3697 / J. Cell Sci. / IRE1 and efferent signaling from the endoplasmic reticulum by Urano (2000)
10.1126/science.287.5453.664 / Science / Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 by Urano (2000)
10.1093/emboj/17.19.5708 / EMBO J. / Cloning of mammalian Ire1 reveals diversity in the ER stress responses by Wang (1998)
10.1016/S0021-9258(19)61473-0 / J. Biol. Chem. / Activation of ATF6 and an ATF6 DNA-binding site by the endoplasmic reticulum stress response by Wang (2000)
10.1016/S1097-2765(00)00133-7 / Mol. Cell / ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs by Ye (2000)
10.1002/j.1460-2075.1990.tb07434.x / EMBO J. / Multiple cDNA clones encoding nuclear proteins that bind to the tax-dependent enhancer of HTLV-1 by Yoshimura (1990)
10.1074/jbc.273.50.33741 / J. Biol. Chem. / Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins; involvement of basic-leucine zipper transcription factors by Yoshida (1998)
10.1128/MCB.20.18.6755-6767.2000 / Mol. Cell. Biol. / ATF6 activated by proteolysis directly binds in the presence of NF-Y (CBF) to the cis-acting element responsible for the mammalian unfolded protein response by Yoshida (2000)
10.1128/MCB.21.4.1239-1248.2001 / Mol. Cell. Biol. / Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6α and 6β that activates the mammalian unfolded protein response by Yoshida (2001)

Dates

Type	When
Created	21 years, 4 months ago (April 17, 2004, 2:47 p.m.)
Deposited	1 year, 7 months ago (Jan. 12, 2024, 6:32 p.m.)
Indexed	12 hours, 33 minutes ago (Aug. 23, 2025, 9:36 p.m.)
Issued	23 years, 8 months ago (Dec. 1, 2001)
Published	23 years, 8 months ago (Dec. 1, 2001)
Published Print	23 years, 8 months ago (Dec. 1, 2001)

Funders 0

None

BibTeX

@article{Yoshida_2001, title={XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor}, volume={107}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/s0092-8674(01)00611-0}, DOI={10.1016/s0092-8674(01)00611-0}, number={7}, journal={Cell}, publisher={Elsevier BV}, author={Yoshida, Hiderou and Matsui, Toshie and Yamamoto, Akira and Okada, Tetsuya and Mori, Kazutoshi}, year={2001}, month=dec, pages={881–891} }

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