DOI: 10.1016/s0092-8674(01)00475-5. Evidence for a Pioneer Round of mRNA Translation

Evidence for a Pioneer Round of mRNA Translation

10.1016/s0092-8674(01)00475-5

Crossref journal-article

Elsevier BV

Cell (78)

Bibliography

Ishigaki, Y., Li, X., Serin, G., & Maquat, L. E. (2001). Evidence for a Pioneer Round of mRNA Translation. Cell, 106(5), 607â617.

Authors 4

Yasuhito Ishigaki (first)
Xiaojie Li (additional)
Guillaume Serin (additional)
Lynne E. Maquat (additional)

References 57 Referenced 465

{'key': '10.1016/S0092-8674(01)00475-5_BIB1', 'first-page': '6326', 'article-title': 'Nonsense but not missense mutations can decrease the abundance of nuclear mRNA for the mouse major urinary protein, while both types of mutations can facilitate exon skipping', 'volume': '14', 'author': 'Belgrader', 'year': '1994', 'journal-title': 'Mol. Cell. Biol.'} / Mol. Cell. Biol. / Nonsense but not missense mutations can decrease the abundance of nuclear mRNA for the mouse major urinary protein, while both types of mutations can facilitate exon skipping by Belgrader (1994)
10.1073/pnas.90.2.482 / Proc. Natl. Acad. Sci. USA / Evidence to implicate translation by ribosomes in the mechanism by which nonsense codons reduce the nuclear level of human triosephosphate isomerase by Belgrader (1993)
{'key': '10.1016/S0092-8674(01)00475-5_BIB3', 'first-page': '8219', 'article-title': 'Mammalian nonsense codons can be cis-effectors of nuclear mRNA half-life', 'volume': '14', 'author': 'Belgrader', 'year': '1994', 'journal-title': 'Mol. Cell. Biol.'} / Mol. Cell. Biol. / Mammalian nonsense codons can be cis-effectors of nuclear mRNA half-life by Belgrader (1994)
10.1017/S1355838200000546 / RNA / Characterization of the biochemical properties of human Upf1 gene product that is involved in nonsense-mediated mRNA decay by Bhattacharya (2000)
10.1002/j.1460-2075.1993.tb05690.x / EMBO J. / Assembly of a processive messenger RNA polyadenylation complex by Bienroth (1993)
10.1002/j.1460-2075.1996.tb00983.x / EMBO J. / A splicing-dependent regulatory mechanism that detects translation signals by Carter (1996)
{'key': '10.1016/S0092-8674(01)00475-5_BIB7', 'series-title': 'RNA-Protein Interaction Protocols', 'article-title': 'An immunoprecipitation-RNA:rPCR method for the in vivo isolation of ribonucleoprotein complexes', 'author': 'Chu', 'year': '1999'} / RNA-Protein Interaction Protocols / An immunoprecipitation-RNA:rPCR method for the in vivo isolation of ribonucleoprotein complexes by Chu (1999)
10.1101/gad.12.11.1665 / Genes Dev. / The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs by Czaplinski (1998)
10.1128/MCB.20.8.2827-2838.2000 / Mol. Cell. Biol. / The role of nuclear cap binding protein Cbc1p of yeast in mRNA termination and degradation by Das (2000)
10.1083/jcb.148.2.239 / J. Cell Biol. / Nuclear eukaryotic initiation factor 4E (eIF4E) colocalizes with splicing factors in speckles by Dostie (2000)
10.1016/S1097-2765(05)00003-1 / Mol. Cell / The yeast nuclear cap binding complex can interact with translation factor eIF4G and mediate translation initiation by Fortes (2000)
10.1093/hmg/8.10.1893 / Hum. Mol. Genet. / Nonsense-mediated mRNA decay in health and disease by Frischmeyer (1999)
10.1146/annurev.biochem.68.1.913 / Annu. Rev. Biochem. / eIF4 initiation factors by Gingras (1999)
{'key': '10.1016/S0092-8674(01)00475-5_BIB14', 'series-title': 'Using Antibodies', 'author': 'Harlow', 'year': '1999'} / Using Antibodies by Harlow (1999)
10.1126/science.275.5299.500 / Science / eIF4G by Hentze (1997)
10.1016/S0092-8674(00)80542-5 / Cell / A perfect message by Hentze (1999)
10.1093/emboj/17.24.7480 / EMBO J. / A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A) binding protein and functions in poly(A)-dependent translation by Imataka (1998)
10.1038/376709a0 / Nature / A cap-binding protein complex mediating U snRNA export by Izaurralde (1995)
10.1016/0092-8674(94)90530-4 / Cell / A nuclear cap binding protein complex involved in pre-mRNA splicing by Izaurralde (1994)
10.1128/MCB.18.1.51 / Mol. Cell. Biol. / RNA recognition motif 2 of yeast Pab1p is required for its functional interaction with eukaryotic translation initiation factor 4G by Kessler (1998)
10.1006/excr.1994.1235 / Exp. Cell Res. / Immunodetection of poly(A) binding protein II in the cell nucleus by Krause (1994)
10.1093/nar/23.3.413 / Nucleic Acids Res. / Nuclear degradation of nonsense-mutated β-globin mRNA by Kugler (1995)
10.1093/emboj/19.24.6860 / EMBO J. / The spliceosome deposits multiple proteins 20–24 nucleotides upstream of mRNA exon-exon junctions by Le Hir (2000)
10.1101/gad.14.9.1098 / Genes Dev. / Pre-mRNA splicing alters mRNP composition by Le Hir (2000)
10.1073/pnas.89.20.9612 / Proc. Natl. Acad. Sci. USA / A fraction of the mRNA 5′ cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus by Lejbkowicz (1992)
10.1111/j.1432-1033.1997.00461.x / Eur. J. Biochem. / The role of the cap structure in RNA processing and nuclear export by Lewis (1997)
10.1016/S1074-7613(00)80466-5 / Immunity / Nonsense surveillance in lymphocytes? by Li (1998)
10.1016/S0092-8674(00)00214-2 / Cell / Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon by Lykke-Andersen (2000)
{'key': '10.1016/S0092-8674(01)00475-5_BIB29', 'first-page': '453', 'article-title': 'When cells stop making sense', 'volume': '1', 'author': 'Maquat', 'year': '1995', 'journal-title': 'RNA'} / RNA / When cells stop making sense by Maquat (1995)
{'key': '10.1016/S0092-8674(01)00475-5_BIB30', 'series-title': 'Translational Control of Gene Expression', 'first-page': '849', 'article-title': 'Nonsense-mediated RNA decay in mammalian cells', 'author': 'Maquat', 'year': '2000'} / Translational Control of Gene Expression / Nonsense-mediated RNA decay in mammalian cells by Maquat (2000)
10.1016/S0092-8674(01)00202-1 / Cell / Quality control of mRNA function by Maquat (2001)
Maquat, L.E., and Serin, G. (2001). Nonsense-mediated mRNA decay: Insights into mechanism from the cellular abundance of human Upf1, Upf2, Upf3 and Upf3X proteins. Cold Spring Harb. Symp. Quant. Biol.: The Ribosome. (Cold Spring Harbor, NY: Cold Spring Harbor Press), in press. (10.1101/sqb.2001.66.313)
10.1016/S1097-2765(01)80003-4 / Mol. Cell / Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G by Marcotrigiano (1999)
10.1128/MCB.21.11.3632-3641.2001 / Mol. Cell. Biol. / Interaction of eukaryotic translation initiation factor 4G with the nuclear cap-binding complex provides a link between nuclear and cytoplasmic functions of the m(7) guanosine cap by McKendrick (2001)
10.1016/0092-8674(92)90224-Z / Cell / Translocation of a specific premessenger ribonucleoprotein particle through the nuclear pore studied with electron microscope tomography by Mehlin (1992)
10.1128/MCB.20.23.8944-8957.2000 / Mol. Cell. Biol. / Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes by Mendell (2000)
10.1128/MCB.18.5.2932 / Mol. Cell. Biol. / Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA by Moriarty (1998)
10.1074/jbc.272.28.17887 / J. Biol. Chem. / Involvement of stressinduced protein kinase and p38/RK mitogen-activated protein kinase signaling pathways in the enhanced phosphorylation of initiation factor 4E in NIH 3T3 cells by Morley (1997)
10.1093/nar/23.20.4034 / Nucleic Acids Res. / Isolation of genomic and cDNA clones encoding bovine poly(A) binding protein II by Nemeth (1995)
10.1038/35035000 / Nature / RNA polymerase II elongation through chromatin by Orphanides (2000)
10.1093/emboj/17.16.4798 / EMBO J. / Cooperative modulation by eIF4G of eIF4E-binding to the mRNA 5′ cap in yeast involves a site partially shared by p20 by Ptushkina (1998)
10.1093/emboj/18.1.270 / EMBO J. / Human eukaryotic translation initiation factor 4G (eIF4G) recruits Mnk1 to phosphorylate eIF4E by Pyronnet (1999)
10.1017/S1355838201000127 / RNA / Evidence that phosphorylation of human Upf1 protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive PI 3-kinase-related kinase signaling pathway by Pal (2001)
10.1128/MCB.21.16.5512-5519.2001 / Mol. Cell. Biol. / Nonsense-mediated decay of HexA mRNA by Rajavel (2001)
10.1038/75120 / Nat. Struct. Biol. / Eukaryotic translation initiation by Sachs (2000)
10.1074/jbc.M002312200 / J. Biol. Chem. / The yeast mRNA-binding protein Npl3p interacts with the cap-binding complex by Shen (2000)
10.1128/MCB.21.1.209-223.2001 / Mol. Cell. Biol. / Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4) by Serin (2001)
10.1093/emboj/19.17.4734 / EMBO J. / Nonsense-mediated decay of glutathione peroxidase 1 mRNA in the cytoplasm depends on intron position by Sun (2000)
10.1073/pnas.95.17.10009 / Proc. Natl. Acad. Sci. USA / A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells by Sun (1998)
10.1093/emboj/17.12.3484 / EMBO J. / Binary specification of nonsense codons by splicing and cytoplasmic translation by Thermann (1998)
10.1083/jcb.133.1.5 / J. Cell Biol. / A nuclear cap-binding complex binds Balbiani ring pre-mRNA cotranscriptionally and accompanies the ribonucleoprotein particle during nuclear export by Visa (1996)
10.1016/0092-8674(91)90119-J / Cell / A novel poly(A)-binding protein acts as a specificity factor in the second phase of messenger RNA polyadenylation by Wahle (1991)
10.1016/S0021-9258(18)53864-3 / J. Biol. Chem. / Mammalian poly(A)-binding protein II. Physical properties and binding to polynucleotides by Wahle (1993)
10.1093/emboj/20.4.880 / EMBO J. / The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts by Wang (2001)
10.1016/0092-8674(79)90093-X / Cell / Transformation of mammalian cells with genes from procaryotes and eucaryotes by Wigler (1979)
10.1017/S1355838298971849 / RNA / Intron function in the nonsense-mediated decay of β-globin mRNA by Zhang (1998)
10.1128/MCB.18.9.5272 / Mol. Cell. Biol. / At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA by Zhang (1998)

Dates

Type	When
Created	21 years, 4 months ago (April 15, 2004, 5:36 a.m.)
Deposited	2 years, 6 months ago (Jan. 26, 2023, 6:10 p.m.)
Indexed	2 weeks, 4 days ago (Aug. 6, 2025, 9:27 a.m.)
Issued	23 years, 11 months ago (Sept. 1, 2001)
Published	23 years, 11 months ago (Sept. 1, 2001)
Published Print	23 years, 11 months ago (Sept. 1, 2001)

Funders 0

None

BibTeX

@article{Ishigaki_2001, title={Evidence for a Pioneer Round of mRNA Translation}, volume={106}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/s0092-8674(01)00475-5}, DOI={10.1016/s0092-8674(01)00475-5}, number={5}, journal={Cell}, publisher={Elsevier BV}, author={Ishigaki, Yasuhito and Li, Xiaojie and Serin, Guillaume and Maquat, Lynne E.}, year={2001}, month=sep, pages={607–617} }

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      "volume": "12",
      "author": "Bienroth",
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      "author": "Carter",
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      "author": "Czaplinski",
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      "article-title": "A fraction of the mRNA 5\u2032 cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus",
      "volume": "89",
      "author": "Lejbkowicz",
      "year": "1992",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
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      "first-page": "461",
      "DOI": "10.1111/j.1432-1033.1997.00461.x",
      "article-title": "The role of the cap structure in RNA processing and nuclear export",
      "volume": "247",
      "author": "Lewis",
      "year": "1997",
      "journal-title": "Eur. J. Biochem."
    },
    {
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      "first-page": "135",
      "DOI": "10.1016/S1074-7613(00)80466-5",
      "article-title": "Nonsense surveillance in lymphocytes?",
      "volume": "8",
      "author": "Li",
      "year": "1998",
      "journal-title": "Immunity"
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB28",
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      "article-title": "Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon",
      "volume": "103",
      "author": "Lykke-Andersen",
      "year": "2000",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB29",
      "first-page": "453",
      "article-title": "When cells stop making sense",
      "volume": "1",
      "author": "Maquat",
      "year": "1995",
      "journal-title": "RNA"
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB30",
      "series-title": "Translational Control of Gene Expression",
      "first-page": "849",
      "article-title": "Nonsense-mediated RNA decay in mammalian cells",
      "author": "Maquat",
      "year": "2000"
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB31",
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      "first-page": "173",
      "DOI": "10.1016/S0092-8674(01)00202-1",
      "article-title": "Quality control of mRNA function",
      "volume": "104",
      "author": "Maquat",
      "year": "2001",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB32",
      "doi-asserted-by": "crossref",
      "unstructured": "Maquat, L.E., and Serin, G. (2001). Nonsense-mediated mRNA decay: Insights into mechanism from the cellular abundance of human Upf1, Upf2, Upf3 and Upf3X proteins. Cold Spring Harb. Symp. Quant. Biol.: The Ribosome. (Cold Spring Harbor, NY: Cold Spring Harbor Press), in press.",
      "DOI": "10.1101/sqb.2001.66.313"
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB33",
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      "first-page": "707",
      "DOI": "10.1016/S1097-2765(01)80003-4",
      "article-title": "Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G",
      "volume": "3",
      "author": "Marcotrigiano",
      "year": "1999",
      "journal-title": "Mol. Cell"
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB34",
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      "first-page": "3632",
      "DOI": "10.1128/MCB.21.11.3632-3641.2001",
      "article-title": "Interaction of eukaryotic translation initiation factor 4G with the nuclear cap-binding complex provides a link between nuclear and cytoplasmic functions of the m(7) guanosine cap",
      "volume": "21",
      "author": "McKendrick",
      "year": "2001",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "605",
      "DOI": "10.1016/0092-8674(92)90224-Z",
      "article-title": "Translocation of a specific premessenger ribonucleoprotein particle through the nuclear pore studied with electron microscope tomography",
      "volume": "69",
      "author": "Mehlin",
      "year": "1992",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "8944",
      "DOI": "10.1128/MCB.20.23.8944-8957.2000",
      "article-title": "Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes",
      "volume": "20",
      "author": "Mendell",
      "year": "2000",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "2932",
      "DOI": "10.1128/MCB.18.5.2932",
      "article-title": "Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA",
      "volume": "18",
      "author": "Moriarty",
      "year": "1998",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "17887",
      "DOI": "10.1074/jbc.272.28.17887",
      "article-title": "Involvement of stressinduced protein kinase and p38/RK mitogen-activated protein kinase signaling pathways in the enhanced phosphorylation of initiation factor 4E in NIH 3T3 cells",
      "volume": "272",
      "author": "Morley",
      "year": "1997",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "4034",
      "DOI": "10.1093/nar/23.20.4034",
      "article-title": "Isolation of genomic and cDNA clones encoding bovine poly(A) binding protein II",
      "volume": "23",
      "author": "Nemeth",
      "year": "1995",
      "journal-title": "Nucleic Acids Res."
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "471",
      "DOI": "10.1038/35035000",
      "article-title": "RNA polymerase II elongation through chromatin",
      "volume": "407",
      "author": "Orphanides",
      "year": "2000",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "4798",
      "DOI": "10.1093/emboj/17.16.4798",
      "article-title": "Cooperative modulation by eIF4G of eIF4E-binding to the mRNA 5\u2032 cap in yeast involves a site partially shared by p20",
      "volume": "17",
      "author": "Ptushkina",
      "year": "1998",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "270",
      "DOI": "10.1093/emboj/18.1.270",
      "article-title": "Human eukaryotic translation initiation factor 4G (eIF4G) recruits Mnk1 to phosphorylate eIF4E",
      "volume": "18",
      "author": "Pyronnet",
      "year": "1999",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "5",
      "DOI": "10.1017/S1355838201000127",
      "article-title": "Evidence that phosphorylation of human Upf1 protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive PI 3-kinase-related kinase signaling pathway",
      "volume": "7",
      "author": "Pal",
      "year": "2001",
      "journal-title": "RNA"
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "5512",
      "DOI": "10.1128/MCB.21.16.5512-5519.2001",
      "article-title": "Nonsense-mediated decay of HexA mRNA",
      "volume": "16",
      "author": "Rajavel",
      "year": "2001",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "356",
      "DOI": "10.1038/75120",
      "article-title": "Eukaryotic translation initiation",
      "volume": "7",
      "author": "Sachs",
      "year": "2000",
      "journal-title": "Nat. Struct. Biol."
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "23718",
      "DOI": "10.1074/jbc.M002312200",
      "article-title": "The yeast mRNA-binding protein Npl3p interacts with the cap-binding complex",
      "volume": "275",
      "author": "Shen",
      "year": "2000",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "209",
      "DOI": "10.1128/MCB.21.1.209-223.2001",
      "article-title": "Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)",
      "volume": "21",
      "author": "Serin",
      "year": "2001",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "4734",
      "DOI": "10.1093/emboj/19.17.4734",
      "article-title": "Nonsense-mediated decay of glutathione peroxidase 1 mRNA in the cytoplasm depends on intron position",
      "volume": "19",
      "author": "Sun",
      "year": "2000",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "10009",
      "DOI": "10.1073/pnas.95.17.10009",
      "article-title": "A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells",
      "volume": "95",
      "author": "Sun",
      "year": "1998",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB50",
      "doi-asserted-by": "crossref",
      "first-page": "3484",
      "DOI": "10.1093/emboj/17.12.3484",
      "article-title": "Binary specification of nonsense codons by splicing and cytoplasmic translation",
      "volume": "17",
      "author": "Thermann",
      "year": "1998",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB51",
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      "first-page": "5",
      "DOI": "10.1083/jcb.133.1.5",
      "article-title": "A nuclear cap-binding complex binds Balbiani ring pre-mRNA cotranscriptionally and accompanies the ribonucleoprotein particle during nuclear export",
      "volume": "133",
      "author": "Visa",
      "year": "1996",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/S0092-8674(01)00475-5_BIB52",
      "doi-asserted-by": "crossref",
      "first-page": "759",
      "DOI": "10.1016/0092-8674(91)90119-J",
      "article-title": "A novel poly(A)-binding protein acts as a specificity factor in the second phase of messenger RNA polyadenylation",
      "volume": "66",
      "author": "Wahle",
      "year": "1991",
      "journal-title": "Cell"
    },
    {
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      "DOI": "10.1016/S0021-9258(18)53864-3",
      "article-title": "Mammalian poly(A)-binding protein II. Physical properties and binding to polynucleotides",
      "volume": "268",
      "author": "Wahle",
      "year": "1993",
      "journal-title": "J. Biol. Chem."
    },
    {
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      "article-title": "The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts",
      "volume": "20",
      "author": "Wang",
      "year": "2001",
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    },
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      "article-title": "Transformation of mammalian cells with genes from procaryotes and eucaryotes",
      "volume": "16",
      "author": "Wigler",
      "year": "1979",
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      "article-title": "Intron function in the nonsense-mediated decay of \u03b2-globin mRNA",
      "volume": "4",
      "author": "Zhang",
      "year": "1998",
      "journal-title": "RNA"
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      "article-title": "At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA",
      "volume": "18",
      "author": "Zhang",
      "year": "1998",
      "journal-title": "Mol. Cell. Biol."
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