DOI: 10.1016/s0092-8674(00)81392-6. The Adaptor Protein Shc Couples a Class of Integrins to the Control of Cell Cycle Progression

The Adaptor Protein Shc Couples a Class of Integrins to the Control of Cell Cycle Progression

10.1016/s0092-8674(00)81392-6

Crossref journal-article

Elsevier BV

Cell (78)

Bibliography

Wary, K. K., Mainiero, F., Isakoff, S. J., Marcantonio, E. E., & Giancotti, F. G. (1996). The Adaptor Protein Shc Couples a Class of Integrins to the Control of Cell Cycle Progression. Cell, 87(4), 733â743.

Authors 5

Kishore K Wary (first)
Fabrizio Mainiero (additional)
Steven J Isakoff (additional)
Eugene E Marcantonio (additional)
Filippo G Giancotti (additional)

References 48 Referenced 607

10.1083/jcb.122.1.209 / J. Cell Biol. / Functional role of the cytoplasmic domain of the integrin α5 subunit by Bauer (1993)
10.1091/mbc.4.6.593 / Mol. Biol. Cell / Ligand-dependent and -independent integrin focal contact localization by Briesewitz (1993)
10.1016/0092-8674(94)90007-8 / Cell / Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels by Brooks (1994)
10.1073/pnas.91.21.10148 / Proc. Natl. Acad. Sci. USA. / Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase by Chen (1994)
10.1002/j.1460-2075.1996.tb00441.x / EMBO J. / Shc adaptor proteins are key transducers of mitogenic signaling mediated by the G protein–coupled thrombin receptor by Chen (1996)
10.1073/pnas.84.18.6471 / Proc. Natl. Acad. Sci. USA. / Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and Von Willebrand factor by Cheresh (1987)
10.1126/science.7716514 / Science / Integrins and signal transduction pathways by Clark (1995)
10.1182/blood.V73.6.1576.1576 / Blood / Interaction of fibronectin with cultured human endothelial cells by Conforti (1989)
10.1083/jcb.129.6.1523 / J. Cell Biol. / Insulin stimulates the tyrosine phosphorylation of caveolin by Corley Mastick (1995)
10.1016/0092-8674(94)90133-3 / Cell / Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells by Cowley (1994)
10.1126/science.271.5248.499 / Science / Dependence of cyclin E–CDK 2 kinase activity on cell anchorage by Fang (1996)
10.1038/363088a0 / Nature / Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras by Gale (1993)
{'key': '10.1016/S0092-8674(00)81392-6_BIB13', 'first-page': '47', 'article-title': 'Integrin-mediated adhesion and signaling in tumorigenesis', 'volume': '1198', 'author': 'Giancotti', 'year': '1994', 'journal-title': 'Biochem. Biophys. Acta'} / Biochem. Biophys. Acta / Integrin-mediated adhesion and signaling in tumorigenesis by Giancotti (1994)
10.1016/0092-8674(90)90098-Y / Cell / Elevated levels of the α5β1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells by Giancotti (1990)
10.1016/0076-6879(94)45017-X / Methods Enzymol. / Expression of heterologous integrin genes in cultured eukaryotic cells by Giancotti (1994)
10.1073/pnas.89.21.10517 / Proc. Natl. Acad. Sci. USA. / Sequence and expression of caveolin, a protein component of caveolae plasma membrane domains phosphorylated on tyrosine in Rous sarcoma virus–transformed fibroblasts by Glenney (1992)
10.1016/0092-8674(93)90110-C / Cell / Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation by Gu (1993)
10.1083/jcb.129.3.867 / J. Cell Biol. / Cooperative signaling by α5β1 and α4β1 integrins regulate metalloproteinase gene expression in fibroblasts adhering to fibronectin by Huhtala (1995)
10.1016/0092-8674(92)90115-S / Cell / Integrins by Hynes (1992)
10.1006/dbio.1996.0314 / Dev. Biol., in press. / Targetted mutations in cell adhesion genes by Hynes (1996)
10.1038/377539a0 / Nature / Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice by Ilic (1995)
10.1016/S0021-9258(17)31717-9 / J. Biol. Chem. / The role of the I domain in ligand binding of the human integrin α1β1 by Kern (1994)
10.1083/jcb.107.4.1589 / J. Cell Biol. / Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures by Kubota (1988)
10.1083/jcb.117.2.437 / J. Cell Biol. / Regulation of fibronectin receptor distribution by LaFlamme (1992)
10.1083/jcb.109.5.2455 / J. Cell Biol. / Endothelial cells use α2β1 integrins as a laminin receptor by Languino (1989)
10.1096/fasebj.7.9.8330681 / FASEB J. / Multi-faceted regulation of cell differentiation via extracellular matrix by Lin (1993)
10.1016/0962-8924(94)90114-7 / Trends Cell Biol. / Caveolae, caveolin, and caveolin-rich membrane domains by Lisanti (1994)
10.1002/j.1460-2075.1995.tb00126.x / EMBO J. / Signal transduction by the α6β4 integrin by Mainiero (1995)
10.1128/MCB.16.3.977 / Mol. Cell. Biol. / Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction by Mohammadi (1996)
10.1038/373573a0 / Nature / Protein modules and signaling networks by Pawson (1995)
10.1016/0092-8674(92)90536-L / Cell / A novel transforming protein (Shc) with an SH2 domain is implicated in mitogenic signal transduction by Pelicci (1992)
10.1242/jcs.109.3.631 / J. Cell Sci. / Requirement of basement membrane for the suppression of programmed cell death in mammary epithelium by Pullan (1996)
10.1038/380538a0 / Nature / A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK by Richardson (1996)
10.1172/JCI114957 / Integrins. J. Clin. Invest. by Ruoslahti (1991)
10.1016/0092-8674(94)90209-7 / Cell / Anchorage dependence, integrins, and apoptosis by Ruoslahti (1994)
{'key': '10.1016/S0092-8674(00)81392-6_BIB36', 'first-page': '2827', 'article-title': 'Formation of Shc–Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins', 'volume': '9', 'author': 'Salcini', 'year': '1994', 'journal-title': 'Oncogene'} / Oncogene / Formation of Shc–Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins by Salcini (1994)
10.1083/jcb.133.1.169 / J. Cell Biol. / Integrin α subunit ratios, cytoplasmic domains, and growth factor synergy regulate muscle proliferation and differentiation by Sastry (1996)
10.1016/0955-0674(94)90097-3 / Curr. Opin. Cell Biol. / Focal adhesion kinase and associated proteins by Schaller (1994)
10.1038/372786a0 / Nature / Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase by Schlaepfer (1994)
10.1126/science.7863328 / Science / Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1–dependent kinase by Skapek (1995)
10.1083/jcb.129.2.473 / J. Cell Biol. / A recombinant tail-less integrin α6β4 subunit disrupts hemidesmosomes, but does not suppress α6β4-mediated cell adhesion to laminins by Spinardi (1995)
10.1002/j.1460-2075.1995.tb00173.x / EMBO J. / Journey to the surface of the cell by Treisman (1995)
10.1111/j.1432-0436.1989.tb00823.x / Differentiation / Antagonistic effects of laminin and fibronectin on the expression of the myogenic phenotype by von der Mark (1989)
10.1128/MCB.16.6.2606 / Mol. Cell. Biol. / Induction of p130CAS signaling complex formation upon integrin-mediated cell adhesion by Vuori (1996)
10.1126/science.270.5240.1326 / Science / Opposing effects of Erk and Jnk–p38 MAP kinases on apoptosis by Xia (1995)
10.1073/pnas.92.13.6161 / Proc. Natl. Acad. Sci. USA. / The α5β1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression by Zhang (1995)
10.1091/mbc.6.3.273 / Mol. Biol. Cell / Integrin-dependent activation of MAP kinase by Zhu (1995)
10.1083/jcb.133.2.391 / J. Cell Biol. / Adhesion dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E–cdk2, and phosphorylation of the retinoblastoma protein by Zhu (1996)

Dates

Type	When
Created	21 years, 4 months ago (April 10, 2004, 5:39 a.m.)
Deposited	3 years, 5 months ago (March 23, 2022, 12:34 p.m.)
Indexed	2 months ago (July 2, 2025, 3:08 p.m.)
Issued	28 years, 10 months ago (Nov. 1, 1996)
Published	28 years, 10 months ago (Nov. 1, 1996)
Published Print	28 years, 10 months ago (Nov. 1, 1996)

Funders 0

None

BibTeX

@article{Wary_1996, title={The Adaptor Protein Shc Couples a Class of Integrins to the Control of Cell Cycle Progression}, volume={87}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/s0092-8674(00)81392-6}, DOI={10.1016/s0092-8674(00)81392-6}, number={4}, journal={Cell}, publisher={Elsevier BV}, author={Wary, Kishore K and Mainiero, Fabrizio and Isakoff, Steven J and Marcantonio, Eugene E and Giancotti, Filippo G}, year={1996}, month=nov, pages={733–743} }

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      "article-title": "Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase",
      "volume": "91",
      "author": "Chen",
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      "first-page": "977",
      "DOI": "10.1128/MCB.16.3.977",
      "article-title": "Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction",
      "volume": "16",
      "author": "Mohammadi",
      "year": "1996",
      "journal-title": "Mol. Cell. Biol."
    },
    {
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      "first-page": "573",
      "DOI": "10.1038/373573a0",
      "article-title": "Protein modules and signaling networks",
      "volume": "373",
      "author": "Pawson",
      "year": "1995",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0092-8674(00)81392-6_BIB31",
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      "first-page": "93",
      "DOI": "10.1016/0092-8674(92)90536-L",
      "article-title": "A novel transforming protein (Shc) with an SH2 domain is implicated in mitogenic signal transduction",
      "volume": "70",
      "author": "Pelicci",
      "year": "1992",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)81392-6_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "631",
      "DOI": "10.1242/jcs.109.3.631",
      "article-title": "Requirement of basement membrane for the suppression of programmed cell death in mammary epithelium",
      "volume": "109",
      "author": "Pullan",
      "year": "1996",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1016/S0092-8674(00)81392-6_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "538",
      "DOI": "10.1038/380538a0",
      "article-title": "A mechanism for regulation of the adhesion-associated protein tyrosine kinase pp125FAK",
      "volume": "380",
      "author": "Richardson",
      "year": "1996",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0092-8674(00)81392-6_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "1",
      "DOI": "10.1172/JCI114957",
      "volume": "87",
      "author": "Ruoslahti",
      "year": "1991",
      "journal-title": "Integrins. J. Clin. Invest."
    },
    {
      "key": "10.1016/S0092-8674(00)81392-6_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "477",
      "DOI": "10.1016/0092-8674(94)90209-7",
      "article-title": "Anchorage dependence, integrins, and apoptosis",
      "volume": "77",
      "author": "Ruoslahti",
      "year": "1994",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)81392-6_BIB36",
      "first-page": "2827",
      "article-title": "Formation of Shc\u2013Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins",
      "volume": "9",
      "author": "Salcini",
      "year": "1994",
      "journal-title": "Oncogene"
    },
    {
      "key": "10.1016/S0092-8674(00)81392-6_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "169",
      "DOI": "10.1083/jcb.133.1.169",
      "article-title": "Integrin \u03b1 subunit ratios, cytoplasmic domains, and growth factor synergy regulate muscle proliferation and differentiation",
      "volume": "133",
      "author": "Sastry",
      "year": "1996",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)81392-6_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "705",
      "DOI": "10.1016/0955-0674(94)90097-3",
      "article-title": "Focal adhesion kinase and associated proteins",
      "volume": "6",
      "author": "Schaller",
      "year": "1994",
      "journal-title": "Curr. Opin. Cell Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)81392-6_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "786",
      "DOI": "10.1038/372786a0",
      "article-title": "Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase",
      "volume": "372",
      "author": "Schlaepfer",
      "year": "1994",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0092-8674(00)81392-6_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "1022",
      "DOI": "10.1126/science.7863328",
      "article-title": "Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1\u2013dependent kinase",
      "volume": "267",
      "author": "Skapek",
      "year": "1995",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0092-8674(00)81392-6_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "473",
      "DOI": "10.1083/jcb.129.2.473",
      "article-title": "A recombinant tail-less integrin \u03b16\u03b24 subunit disrupts hemidesmosomes, but does not suppress \u03b16\u03b24-mediated cell adhesion to laminins",
      "volume": "129",
      "author": "Spinardi",
      "year": "1995",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)81392-6_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "4905",
      "DOI": "10.1002/j.1460-2075.1995.tb00173.x",
      "article-title": "Journey to the surface of the cell",
      "volume": "14",
      "author": "Treisman",
      "year": "1995",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S0092-8674(00)81392-6_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "150",
      "DOI": "10.1111/j.1432-0436.1989.tb00823.x",
      "article-title": "Antagonistic effects of laminin and fibronectin on the expression of the myogenic phenotype",
      "volume": "40",
      "author": "von der Mark",
      "year": "1989",
      "journal-title": "Differentiation"
    },
    {
      "key": "10.1016/S0092-8674(00)81392-6_BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "2606",
      "DOI": "10.1128/MCB.16.6.2606",
      "article-title": "Induction of p130CAS signaling complex formation upon integrin-mediated cell adhesion",
      "volume": "16",
      "author": "Vuori",
      "year": "1996",
      "journal-title": "Mol. Cell. Biol."
    },
    {
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      "first-page": "1326",
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      "article-title": "Opposing effects of Erk and Jnk\u2013p38 MAP kinases on apoptosis",
      "volume": "270",
      "author": "Xia",
      "year": "1995",
      "journal-title": "Science"
    },
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      "DOI": "10.1073/pnas.92.13.6161",
      "article-title": "The \u03b15\u03b21 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression",
      "volume": "92",
      "author": "Zhang",
      "year": "1995",
      "journal-title": "Proc. Natl. Acad. Sci. USA."
    },
    {
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      "first-page": "273",
      "DOI": "10.1091/mbc.6.3.273",
      "article-title": "Integrin-dependent activation of MAP kinase",
      "volume": "6",
      "author": "Zhu",
      "year": "1995",
      "journal-title": "Mol. Biol. Cell"
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      "article-title": "Adhesion dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E\u2013cdk2, and phosphorylation of the retinoblastoma protein",
      "volume": "133",
      "author": "Zhu",
      "year": "1996",
      "journal-title": "J. Cell Biol."
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