DOI: 10.1016/s0092-8674(00)80942-3. Ump1p Is Required for Proper Maturation of the 20S Proteasome and Becomes Its Substrate upon Completion of the Assembly

Ump1p Is Required for Proper Maturation of the 20S Proteasome and Becomes Its Substrate upon Completion of the Assembly

10.1016/s0092-8674(00)80942-3

Crossref journal-article

Elsevier BV

Cell (78)

Bibliography

Ramos, P. C., HÃ¶ckendorff, J., Johnson, E. S., Varshavsky, A., & Dohmen, R. J. (1998). Ump1p Is Required for Proper Maturation of the 20S Proteasome and Becomes Its Substrate upon Completion of the Assembly. Cell, 92(4), 489â499.

Authors 5

Paula C Ramos (first)
Jörg Höckendorff (additional)
Erica S Johnson (additional)
Alexander Varshavsky (additional)
R.Jürgen Dohmen (additional)

References 40 Referenced 277

10.1534/genetics.112.541.test / Genetics / A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains by Alani (1987)
10.1073/pnas.94.14.7156 / Proc. Natl. Acad. Sci. USA / Identification of the yeast 20S proteasome catalytic centers and subunit interactions required for active-site formation by Arendt (1997)
Bachmair, A., Finley, D., and Varshavsky, A. (1986). In vivo half-life of a protein is a function of its amino-terminal residue. Science 234, 179–186. (10.1126/science.3018930)
10.1074/jbc.270.20.12065 / J. Biol. Chem. / Yeast N-terminal amidase—a new enzyme and component of the N-end rule pathway by Baker (1995)
10.1002/j.1460-2075.1990.tb07516.x / EMBO J. / The recognition component of the N-end rule pathway by Bartel (1990)
10.1016/S0092-8674(00)80171-3 / Cell / Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assembly by Chen (1996)
10.1146/annurev.bi.65.070196.004101 / Annu. Rev. Biochem. / Structure and functions of the 20S and 26S proteasomes by Coux (1996)
10.1016/S0021-9258(17)37244-7 / J. Biol. Chem. / A 26S protease subunit that binds ubiquitin conjugates by Deveraux (1994)
10.1073/pnas.88.16.7351 / Proc. Natl. Acad. Sci. USA / The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme by Dohmen (1991)
10.1126/science.8122109 / Science / Heat-inducible degron by Dohmen (1994)
10.1074/jbc.270.30.18099 / J. Biol. Chem. / An essential yeast gene encoding a homolog of ubiquitin-activating enzyme by Dohmen (1995)
10.1016/0014-5793(94)01177-X / FEBS Lett. / The 26S proteasome of the yeast Saccharomyces cerevisiae by Fischer (1994)
10.1016/0022-2836(94)90003-5 / J. Mol. Biol. / 20S proteasomes are assembled via distinct precursor complexes by Frentzel (1994)
10.1038/366358a0 / Nature / S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase by Ghislain (1993)
10.1016/0378-1119(88)90185-0 / Gene / New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites by Gietz (1988)
10.1038/386463a0 / Nature / Structure of 20S proteasome from yeast at 2.4 Å resolution by Groll (1997)
10.1016/S0021-9258(18)53509-2 / J. Biol. Chem. / PRE2, highly homologous to the human major histocompatibility complex-linked RING10 gene, codes for a yeast proteasome subunit necessary for chymotryptic activity and degradation of ubiquitinated proteins by Heinemeyer (1993)
10.1074/jbc.272.40.25200 / J. Biol. Chem. / The active sites of the eukaryotic 20S proteasome and their involvement in subunit precursor processing by Heinemeyer (1997)
10.1146/annurev.genet.30.1.405 / Annu. Rev. Genet. / Ubiquitin-dependent protein degradation by Hochstrasser (1996)
Hochstrasser, M., and Varshavsky, A. (1990). In vivo degradation of a transcriptional regulator: the yeast α2 repressor. Cell 61, 697–708. (10.1016/0092-8674(90)90481-S)
10.1101/SQB.1995.060.01.054 / Cold Spring Harb. Symp. Quant. Biol. / The doa pathway—studies on the functions and mechanisms of ubiquitin-dependent protein degradation in the yeast Saccharomyces cerevisiae by Hochstrasser (1995)
10.1016/S0021-9258(18)47564-3 / J. Biol. Chem. / Purification of two high molecular weight proteases from rabbit reticulocyte lysate by Hough (1987)
10.1016/0092-8674(95)90021-7 / Cell / Selective protein degradation—a journey's end within the proteasome by Jentsch (1995)
10.1074/jbc.270.29.17442 / J. Biol. Chem. / A proteolytic pathway that recognizes ubiquitin as a degradation signal by Johnson (1995)
10.1038/361369a0 / Nature / Resistance to cadmium mediated by ubiquitin-dependent proteolysis by Jungmann (1993)
10.1093/genetics/132.3.665 / Genetics / Construction of a GAL1-regulated yeast cDNA expression library and its application to the identification of genes whose overexpression causes lethality in yeast by Liu (1992)
10.1126/science.7725097 / Science / Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 Å resolution by Löwe (1995)
10.1016/S0968-0004(97)01117-1 / Trends Biochem. Sci. / Self-compartmentalizing proteases by Lupas (1997)
10.1093/emboj/16.17.5363 / EMBO J. / Intermediates in the formation of mouse 20S proteasomes by Nandi (1997)
10.1016/0968-0004(94)90115-5 / Trends Biochem. Sci. / Proteasomes by Peters (1994)
10.1071/PP9950893 / Austr. J. Plant Physiol. / The presence of ubiquitin-protein conjugates in plant chloroplast lysates is due to cytosolic contamination by Ramos (1995)
10.1016/0378-1119(87)90232-0 / Gene / A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector by Rose (1987)
10.1016/0076-6879(91)94022-5 / Methods Enzymol. / Targeting, disruption, replacement, and allele rescue by Rothstein (1991)
10.1006/jmbi.1997.0947 / J. Mol. Biol. / Maturation of mammalian 20S proteasome by Schmidtke (1997)
10.1126/science.7725107 / Science / Proteasome from Thermoplasma acidophilum by Seemüller (1995)
10.1038/382468a0 / Nature / Autocatalytic processing of the 20S proteasome by Seemüller (1996)
10.1093/genetics/122.1.19 / Genetics / A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae by Sikorski (1989)
10.1073/pnas.93.22.12142 / Proc. Nat. Acad. Sci. USA / The N-end rule—functions, mysteries, uses by Varshavsky (1996)
10.1016/S0968-0004(97)01122-5 / Trends Biochem. Sci. / The ubiquitin system by Varshavsky (1997)
10.1074/jbc.270.46.27687 / J. Biol. Chem. / In vivo assembly of the proteasomal complexes, implications for antigen processing by Yang (1995)

Dates

Type	When
Created	21 years, 4 months ago (April 10, 2004, 5:39 a.m.)
Deposited	4 years, 2 months ago (June 15, 2021, 9:48 a.m.)
Indexed	2 months, 2 weeks ago (June 4, 2025, 9:56 p.m.)
Issued	27 years, 6 months ago (Feb. 1, 1998)
Published	27 years, 6 months ago (Feb. 1, 1998)
Published Print	27 years, 6 months ago (Feb. 1, 1998)

Funders 0

None

BibTeX

@article{Ramos_1998, title={Ump1p Is Required for Proper Maturation of the 20S Proteasome and Becomes Its Substrate upon Completion of the Assembly}, volume={92}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/s0092-8674(00)80942-3}, DOI={10.1016/s0092-8674(00)80942-3}, number={4}, journal={Cell}, publisher={Elsevier BV}, author={Ramos, Paula C and Höckendorff, Jörg and Johnson, Erica S and Varshavsky, Alexander and Dohmen, R.Jürgen}, year={1998}, month=feb, pages={489–499} }

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      "author": "Rose",
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      "author": "Rothstein",
      "year": "1991",
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      "author": "Schmidtke",
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      "author": "Sikorski",
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      "year": "1996",
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      "article-title": "In vivo assembly of the proteasomal complexes, implications for antigen processing",
      "volume": "270",
      "author": "Yang",
      "year": "1995",
      "journal-title": "J. Biol. Chem."
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