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Cell (78)
Bibliography

Greenberg, R. A., Chin, L., Femino, A., Lee, K.-H., Gottlieb, G. J., Singer, R. H., Greider, C. W., & DePinho, R. A. (1999). Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse. Cell, 97(4), 515–525.

Authors 8
  1. Roger A Greenberg (first)
  2. Lynda Chin (additional)
  3. Andrea Femino (additional)
  4. Kee-Ho Lee (additional)
  5. Geoffrey J Gottlieb (additional)
  6. Robert H Singer (additional)
  7. Carol W Greider (additional)
  8. Ronald A DePinho (additional)
References 58 Referenced 297
  1. {'key': '10.1016/S0092-8674(00)80761-8_BIB1', 'first-page': '197', 'article-title': 'Telomere maintenance in tumor cells', 'volume': '28', 'author': 'Bacchetti', 'year': '1996', 'journal-title': 'Cancer Surv.'} / Cancer Surv. / Telomere maintenance in tumor cells by Bacchetti (1996)
  2. 10.1038/25867 / Nature / p14ARF links the tumor suppressors Rb and p53 by Bates (1998)
  3. 10.1002/(SICI)1098-2744(199712)20:4<329::AID-MC1>3.0.CO;2-E / Mol. Carcinog. / Telomerase and cell proliferation in mouse skin papillomas by Bednarek (1997)
  4. 10.1016/S1097-2765(00)80143-4 / Mol. Cell / Localization of ASH1 mRNA particles in living yeast by Bertrand (1998)
  5. 10.1038/ng0296-200 / Nat. Genet. / Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis by Blasco (1996)
  6. 10.1016/S0092-8674(01)80006-4 / Cell / Telomere shortening and tumor formation by mouse cells lacking telomerase RNA by Blasco (1997)
  7. 10.1126/science.279.5349.349 / Science / Extension of life-span by introduction of telomerase into normal human cells by Bodnar (1998)
  8. 10.1128/MCB.16.7.3765 / Mol. Cell. Biol. / Telomerase activation in mouse mammary tumors by Broccoli (1996)
  9. 10.1002/j.1460-2075.1995.tb00098.x / EMBO / Telomere elongation in immortal human cells without detectable telomerase activity by Bryan (1995)
  10. 10.1093/hmg/6.6.921 / Hum. Mol. Genet. / The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit by Bryan (1997)
  11. {'key': '10.1016/S0092-8674(00)80761-8_BIB10', 'first-page': '893', 'article-title': 'Telomerase activity in normal and malignant murine tissues', 'volume': '11', 'author': 'Chadeneau', 'year': '1995', 'journal-title': 'Oncogene'} / Oncogene / Telomerase activity in normal and malignant murine tissues by Chadeneau (1995)
  12. 10.1016/S0092-8674(00)80762-X / Cell / p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis by Chin (1999)
  13. {'key': '10.1016/S0092-8674(00)80761-8_BIB12', 'first-page': '2295', 'article-title': 'The three transforming regions of SV40 T antigen are required for immortalization of primary mouse embryo fibroblasts', 'volume': '11', 'author': 'Conzen', 'year': '1995', 'journal-title': 'Oncogene'} / Oncogene / The three transforming regions of SV40 T antigen are required for immortalization of primary mouse embryo fibroblasts by Conzen (1995)
  14. 10.1002/j.1460-2075.1992.tb05245.x / EMBO / Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity by Counter (1992)
  15. 10.1073/pnas.95.25.14723 / Proc. Natl. Acad. Sci. USA / Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization by Counter (1998)
  16. 10.1101/gad.12.15.2434 / Genes Dev. / E1A signaling to p53 involves the p19ARF tumor suppressor by de Stanchina (1998)
  17. 10.1038/251616a0 / Nature / Evolution of cell senescence, atherosclerosis and benign tumors by Dykhuizen (1974)
  18. 10.1126/science.280.5363.585 / Science / Visualization of single RNA transcripts in situ by Femino (1998)
  19. 10.1038/sj.onc.1201933 / Oncogene / Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation by Greenberg (1998)
  20. 10.1038/sj.onc.1202669 / Oncogene / Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation by Greenberg (1999)
  21. 10.1016/0006-291X(91)91403-Y / Biochem. Biophys. Res. Comm. / Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of life span in human diploid fibroblasts, TIG-1 by Hara (1991)
  22. 10.1038/345458a0 / Nature / Telomeres shorten during ageing of human fibroblasts by Harley (1990)
  23. 10.1016/0014-4827(61)90192-6 / Exp. Cell. Res. / The serial cultivation of human diploid strains by Hayflick (1961)
  24. 10.1016/S0092-8674(00)80452-3 / Cell / Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF by Kamijo (1997)
  25. 10.1073/pnas.95.14.8292 / Proc. Natl. Acad. Sci. USA / Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2 by Kamijo (1998)
  26. 10.1126/science.283.5406.1321 / Science / P53- and ATM-dependent apoptosis induced by telomeres lacking TRF2 by Karlseder (1999)
  27. 10.1126/science.7605428 / Science / Specific association of human telomerase activity with immortal cells and cancer by Kim (1994)
  28. 10.1016/0888-7543(91)90128-2 / Genomics / Mouse minor satellite genetically maps to the centromere and is physically linked to the proximal telomere by Kipling (1991)
  29. 10.1038/23962 / Nature / Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells by Kiyono (1998)
  30. 10.1093/jnci/76.4.703 / J. Natl. Cancer Inst. / Spontaneous immortalization rate of cultured Chinese hamster cells by Kraemer (1986)
  31. 10.1038/33345 / Nature / Essential role of mouse telomerase in highly proliferative organs by Lee (1998)
  32. 10.1101/gad.12.19.3008 / Genes Dev. / Premature senescence involving p53 and p16 is activated in response to constituitive MEK/MAPK mitogenic signaling by Lin (1998)
  33. 10.1101/gad.11.5.663 / Genes Dev. / Cooperating oncogenes converge to regulate cyclin/cdk complexes by Lloyd (1997)
  34. 10.1016/0092-8674(93)90234-H / Cell / An alternative pathway for yeast telomere maintenance rescues est1- senescence by Lundblad (1993)
  35. 10.1073/pnas.95.18.10471 / Proc. Natl. Acad. Sci. USA / Expression of mouse telomerase catalytic subunit in embryos and adult tissues by Martin-Rivera (1998)
  36. 10.1101/gad.10.14.1822 / Genes Dev. / Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase by McEachern (1996)
  37. 10.1038/2517 / Nat. Genet. / Circular chromosome formation in a fission yeast mutant defective in two ATM homologues by Naito (1998)
  38. 10.1126/science.282.5388.493 / Science / Two modes of survival of fission yeast without telomerase by Nakamura (1998)
  39. 10.1038/580 / Nat. Genet. / Severe growth defect in mouse cells lacking the telomerase RNA component by Niida (1998)
  40. 10.1038/25870 / Nature / p19ARF links the tumor suppressor p53 to Ras by Palermo (1998)
  41. 10.1016/S0092-8674(00)81400-2 / Cell / The INK4a tumor suppressor gene product, p19ARF, interacts with MDM2 and neutralizes MDM2’s inhibition of p53 by Pomerantz (1998)
  42. 10.1073/pnas.92.11.4818 / Proc. Natl. Acad. Sci. USA / Developmental and tissue-specific regulation of mouse telomerase and telomere length by Prowse (1995)
  43. 10.1073/pnas.95.22.13194 / Proc. Natl. Acad. Sci. USA / p19(Arf) induces p-53-dependent apoptosis during abelson virus-medicated pre-B cell transformation by Radfar (1998)
  44. 10.1016/S0092-8674(00)80580-2 / Cell. / Longevity, stress response, and cancer in aging telomerase deficient mice by Rudolph (1999)
  45. 10.1289/ehp.919359 / Environ. Health Perspect. / Senescence as a mode of tumor suppression by Sager (1991)
  46. 10.1038/366704a0 / Nature / A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/cdk4 by Serrano (1993)
  47. 10.1016/S0092-8674(00)81079-X / Cell / Role of the INK4a locus in tumor suppression and cell mortality by Serrano (1996)
  48. 10.1016/0014-4827(91)90453-2 / Exp. Cell Res. / A role for both RB and p53 in the regulation of human cellular senescence by Shay (1991)
  49. 10.1101/gad.12.19.2984 / Genes Dev. / Tumor surveillance via the ARF-p53 pathway by Sherr (1998)
  50. 10.1093/emboj/17.17.5001 / EMBO J. / The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2 by Stott (1998)
  51. 10.1016/S0960-9822(98)70109-5 / Curr. Biol. / Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span by Vaziri (1998)
  52. 10.1101/gad.12.12.1769 / Genes Dev. / Myc activates telomerase by Wang (1998)
  53. 10.1016/S0962-8924(00)89044-3 / Trends Cell Biol. / Time, telomeres and tumours by Wright (1995)
  54. 10.1038/6010 / Nat. Genet. / Direct activation of TERT transcription by c-Myc by Wu (1999)
  55. 10.1016/S0092-8674(00)81401-4 / Cell / ARF promotes MDM2 degradation and stabilizes p53 by Zhang (1998)
  56. 10.1101/gad.12.19.2997 / Genes Dev. / Senescence of human fibroblasts induced by oncogenic Raf by Zhu (1998)
  57. 10.1073/pnas.94.14.7423 / Proc. Natl. Acad. Sci. USA / Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats by Zijlmans (1997)
  58. 10.1101/gad.12.15.2424 / Genes Dev. / Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization by Zindy (1998)
Dates
Type When
Created 21 years, 4 months ago (April 10, 2004, 5:39 a.m.)
Deposited 5 years, 4 months ago (March 31, 2020, 7:07 p.m.)
Indexed 2 months ago (June 27, 2025, 9:45 a.m.)
Issued 26 years, 3 months ago (May 1, 1999)
Published 26 years, 3 months ago (May 1, 1999)
Published Print 26 years, 3 months ago (May 1, 1999)
Funders 0

None

@article{Greenberg_1999, title={Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse}, volume={97}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/s0092-8674(00)80761-8}, DOI={10.1016/s0092-8674(00)80761-8}, number={4}, journal={Cell}, publisher={Elsevier BV}, author={Greenberg, Roger A and Chin, Lynda and Femino, Andrea and Lee, Kee-Ho and Gottlieb, Geoffrey J and Singer, Robert H and Greider, Carol W and DePinho, Ronald A}, year={1999}, month=may, pages={515–525} }