Crossref journal-article
Elsevier BV
Cell (78)
Bibliography

Zhang, H. S., Postigo, A. A., & Dean, D. C. (1999). Active Transcriptional Repression by the Rb–E2F Complex Mediates G1 Arrest Triggered by p16INK4a, TGFβ, and Contact Inhibition. Cell, 97(1), 53–61.

Authors 3
  1. H.Steven Zhang (first)
  2. Antonio A Postigo (additional)
  3. Douglas C Dean (additional)
References 65 Referenced 294
  1. {'key': '10.1016/S0092-8674(00)80714-X_BIB1', 'first-page': '79', 'article-title': 'The cellular effects of E2F overexpression', 'volume': '208', 'author': 'Adams', 'year': '1996', 'journal-title': 'Curr. Top. Microbiol. Immunol.'} / Curr. Top. Microbiol. Immunol. / The cellular effects of E2F overexpression by Adams (1996)
  2. 10.1074/jbc.270.15.8837 / J. Biol. Chem. / The retinoblastoma susceptibility gene product represses transcription when directly bound to the promoter by Adnane (1995)
  3. 10.1038/25867 / Nature / p14ARF links the tumour suppressors RB and p53 by Bates (1998)
  4. 10.1038/35404 / Nature / Retinoblastoma protein recruits histone deacetylase to repress transcription by Brehm (1998)
  5. 10.1128/MCB.15.6.3256 / Mol. Cell. Biol. / Direct transcriptional repression by pRb and its reversal by specific cyclins by Bremner (1995)
  6. 10.1016/0092-8674(91)90557-F / Cell / The E2F transcription factor is a cellular target for the RB protein by Chellappan (1991)
  7. {'key': '10.1016/S0092-8674(00)80714-X_BIB7', 'first-page': '6314', 'article-title': 'A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4', 'volume': '13', 'author': 'Cress', 'year': '1993', 'journal-title': 'Mol. Cell. Biol.'} / Mol. Cell. Biol. / A genetic analysis of the E2F1 gene distinguishes regulation by Rb, p107, and adenovirus E4 by Cress (1993)
  8. 10.1101/gad.9.23.2873 / Genes Dev. / E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity by DeGregori (1995)
  9. 10.1007/BF00690418 / Cancer Metastasis Rev. / The cell cycle and the retinoblastoma protein family by Ewen (1994)
  10. 10.1016/0092-8674(93)90723-4 / Cell / TGF-beta inhibition of Cdk4 synthesis is linked to cell cycle arrest by Ewen (1993)
  11. 10.1101/gad.9.2.204 / Genes Dev. / p53-dependent repression of cdk4 translation in TGF-beta induced cell-cycle arrest by Ewen (1995)
  12. 10.1038/sj.onc.1200940 / Oncogene / Functional roles of E2F in cell cycle regulation by Fan (1997)
  13. 10.1016/S0092-8674(00)81255-6 / Cell / E2F-1 functions in mice to promote apoptosis and suppress proliferation by Field (1996)
  14. 10.1016/S0092-8674(00)80994-0 / Cell / Cdk2 kinase is required for entry into mitosis as a positive regulator of Cdc2-cyclin B kinase activity by Guadagno (1996)
  15. 10.1101/gad.8.24.2939 / Genes Dev. / Growth suppression by p18, a p16(ink4/mts1)- and p14(ink4b/mts2)-related cdk6 inhibitor, correlates with wild-type pRb function by Guan (1994)
  16. {'key': '10.1016/S0092-8674(00)80714-X_BIB16', 'first-page': '3431', 'article-title': 'Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene', 'volume': '12', 'author': 'Hamel', 'year': '1992', 'journal-title': 'Mol. Cell. Biol.'} / Mol. Cell. Biol. / Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene by Hamel (1992)
  17. 10.1101/gad.7.10.1850 / Genes Dev. / Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation by Helin (1993)
  18. 10.1128/MCB.15.6.3082 / Mol. Cell. Biol. / E2f-5, a new e2f family member that interacts with p130 in vivo by Hijmans (1995)
  19. 10.1126/science.283.5403.851 / Science / Requirement of cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts by Hinchcliffe (1999)
  20. 10.1016/0092-8674(92)90249-C / Cell / Regulation of retinoblastoma protein functions by ectopic expression of human cyclins by Hinds (1992)
  21. 10.1101/gad.11.14.1840 / Genes Dev. / E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction by Hsieh (1997)
  22. 10.1083/jcb.140.2.271 / J. Cell Biol. / Identification of a preinitiation step in DNA replication that is independent of origin recognition complex and cdc6, but dependent on cdk2 by Hua (1998)
  23. 10.1038/387417a0 / Nature / Repression of the CDK activator cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the cdk inhibitor p15 by Iavarone (1997)
  24. 10.1038/365349a0 / Nature / Expression of transcription factor E2F1 induces quiescent cells to enter S phase by Johnson (1993)
  25. 10.1126/science.8475385 / Science / Negative regulation of G1 in mammalian cells by Koff (1993)
  26. 10.1038/375506a0 / Nature / Tumour-derived p16 alleles encoding proteins defective in cell cycle inhibition by Koh (1995)
  27. 10.1126/science.8248803 / Science / Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members by Krek (1993)
  28. 10.1016/0092-8674(95)90141-8 / Cell / Cyclin A kinase regulation of E2F-1 DNA binding function underlies suppression of an S-phase checkpoint by Krek (1995)
  29. 10.1016/0955-0674(94)90057-4 / Curr. Opin. Cell Biol. / Dp and E2F proteins by Lam (1994)
  30. 10.1016/0968-0004(94)90202-X / Trends Biochem. Sci. / DRTF1/E2F by La Thangue (1994)
  31. {'key': '10.1016/S0092-8674(00)80714-X_BIB31', 'first-page': '7813', 'article-title': 'The retinoblastoma protein binds to a family of E2F transcription factors', 'volume': '13', 'author': 'Lees', 'year': '1993', 'journal-title': 'Mol. Cell. Biol.'} / Mol. Cell. Biol. / The retinoblastoma protein binds to a family of E2F transcription factors by Lees (1993)
  32. 10.1016/0092-8674(90)90590-B / Cell / The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T by Ludlow (1990)
  33. 10.1038/375503a0 / Nature / Retinoblastoma protein-dependent cell cycle inhibition by the tumor suppressor p16 by Lukas (1995)
  34. 10.1128/MCB.16.3.1047 / Mol. Cell. Biol. / Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4a-mediated growth suppression by Lukas (1996)
  35. 10.1128/MCB.18.2.753 / Mol. Cell. Biol. / Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes by Lundberg (1997)
  36. 10.1016/S0092-8674(00)80940-X / Cell / Rb interacts with histone deacetylase to repress transcription by Luo (1998)
  37. 10.1038/35410 / Nature / Retinoblastoma protein represses transcription by recruiting a histone deacetylase by Magnaghi-Jaulin (1998)
  38. {'key': '10.1016/S0092-8674(00)80714-X_BIB38', 'first-page': '947', 'article-title': 'TGF-beta signaling', 'volume': '85', 'author': 'Massague', 'year': '1996', 'journal-title': 'Cell'} / Cell / TGF-beta signaling by Massague (1996)
  39. 10.1126/science.2588006 / Science / Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product by Mihara (1989)
  40. 10.1126/science.1411535 / Science / E2F by Nevins (1992)
  41. {'key': '10.1016/S0092-8674(00)80714-X_BIB41', 'first-page': '351', 'article-title': 'Perturbation of cell cycle regulators in human cancer', 'volume': '27', 'author': 'Palmero', 'year': '1996', 'journal-title': 'Cancer Surv.'} / Cancer Surv. / Perturbation of cell cycle regulators in human cancer by Palmero (1996)
  42. 10.1016/S1097-2765(00)80273-7 / Mol. Cell / Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors by Pan (1998)
  43. 10.1101/gad.11.14.1853 / Genes Dev. / Induction of DNA synthesis and apoptosis are separable functions of E2F-1 by Phillips (1997)
  44. 10.1101/gad.8.1.9 / Genes Dev. / p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest by Polyak (1994)
  45. 10.1016/S0092-8674(00)81400-2 / Cell / The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2’s inhibition of p53 by Pomerantz (1998)
  46. 10.1073/pnas.91.23.10918 / Proc. Natl. Acad. Sci. USA / Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis by Qin (1994)
  47. 10.1128/MCB.15.2.742 / Mol. Cell. Biol. / The transcription factor E2F-1 is a downstream target of Rb action by Qin (1995)
  48. 10.1101/gad.9.15.1831 / Genes Dev. / Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta by Reynisdottir (1995)
  49. 10.1101/SQB.1994.059.01.006 / Cold Spring Harb. Symb. Quant. Biol. / Cyclins, Cdks, and cyclin kinase inhibitors by Roberts (1994)
  50. 10.1073/pnas.92.25.11544 / Proc. Natl. Acad. Sci. USA / A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites by Sellers (1995)
  51. 10.1038/366704a0 / Nature / A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4 by Serrano (1993)
  52. {'key': '10.1016/S0092-8674(00)80714-X_BIB52', 'first-page': '8166', 'article-title': 'Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis', 'volume': '14', 'author': 'Shan', 'year': '1994', 'journal-title': 'Mol. Cell. Biol.'} / Mol. Cell. Biol. / Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis by Shan (1994)
  53. 10.1126/science.274.5293.1672 / Science / Cancer cell cycles by Sherr (1996)
  54. 10.1101/gad.9.10.1149 / Genes Dev. / Inhibitors of mammalian G1 cyclin-dependent kinases by Sherr (1995)
  55. {'key': '10.1016/S0092-8674(00)80714-X_BIB55', 'first-page': '1', 'article-title': 'Introduction to the E2F family', 'volume': '208', 'author': 'Slansky', 'year': '1996', 'journal-title': 'Curr. Top. Microbiol. Immunol.'} / Curr. Top. Microbiol. Immunol. / Introduction to the E2F family by Slansky (1996)
  56. 10.1083/jcb.142.2.557 / J. Cell Biol. / E-Cadherin-dependent growth suppression is mediated by the cyclin-dependent kinase inhibitor p27(KIP1) by St. Croix (1998)
  57. 10.1016/S1097-2765(00)80274-9 / Mol. Cell / Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos by Tsai (1998)
  58. 10.1126/science.8266103 / Science / Distinct roles for cyclin-dependent kinases in cell cycle control by van den Heuvel (1993)
  59. 10.1016/0092-8674(95)90385-2 / Cell / The retinoblastoma protein and cell cycle control by Weinberg (1995)
  60. 10.1016/S0092-8674(00)81244-1 / Cell / E2F and cell proliferation by Weinberg (1996)
  61. 10.1038/358259a0 / Nature / Retinoblastoma protein switches the E2F site from positive to negative element by Weintraub (1992)
  62. 10.1038/375812a0 / Nature / Mechanism of active transcriptional repression by the retinoblastoma protein by Weintraub (1995)
  63. 10.1073/pnas.91.9.3602 / Proc. Natl. Acad. Sci. USA / p53 and E2F-1 cooperate to mediate apoptosis by Wu (1994)
  64. 10.1016/S0092-8674(00)81254-4 / Cell / Tumor induction and tissue atrophy in mice lacking E2F-1 by Yamasaki (1996)
  65. 10.1016/S0092-8674(00)81401-4 / Cell / ARF promotes MDM2 degradation and stabilizes p53 by Zhang (1998)
Dates
Type When
Created 21 years, 1 month ago (June 30, 2004, 8:27 a.m.)
Deposited 2 years, 7 months ago (Jan. 28, 2023, 10:16 a.m.)
Indexed 4 weeks, 2 days ago (July 30, 2025, 11:33 a.m.)
Issued 26 years, 4 months ago (April 1, 1999)
Published 26 years, 4 months ago (April 1, 1999)
Published Print 26 years, 4 months ago (April 1, 1999)
Funders 0

None

@article{Zhang_1999, title={Active Transcriptional Repression by the Rb–E2F Complex Mediates G1 Arrest Triggered by p16INK4a, TGFβ, and Contact Inhibition}, volume={97}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/s0092-8674(00)80714-x}, DOI={10.1016/s0092-8674(00)80714-x}, number={1}, journal={Cell}, publisher={Elsevier BV}, author={Zhang, H.Steven and Postigo, Antonio A and Dean, Douglas C}, year={1999}, month=apr, pages={53–61} }