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Cell (78)
Bibliography

Emsley, J., Knight, C. G., Farndale, R. W., Barnes, M. J., & Liddington, R. C. (2000). Structural Basis of Collagen Recognition by Integrin α2β1. Cell, 101(1), 47–56.

Authors 5
  1. Jonas Emsley (first)
  2. C.Graham Knight (additional)
  3. Richard W. Farndale (additional)
  4. Michael J. Barnes (additional)
  5. Robert C. Liddington (additional)
References 61 Referenced 840
  1. 10.1016/S0263-7855(98)80030-1 / J. Mol. Graphics / A fast algorithm for rendering space-filling molecule pictures by Bacon (1988)
  2. 10.1016/S0969-2126(98)00093-8 / Structure / Cation binding to the integrin CD11b I domain and activation model assessment by Baldwin (1998)
  3. 10.1126/science.7695699 / Science / Crystal and molecular structure of a collagen-like peptide at 1.9Å resolution by Bella (1994)
  4. 10.1073/pnas.95.8.4140 / Proc. Natl. Acad. Sci. USA / The structure of the two amino-terminal domains of human ICAM-1 suggests how it functions as a rhinovirus receptor and as an LFA-1 integrin ligand by Bella (1998)
  5. 10.1002/jlb.55.4.501 / J. Leukocyte Biol. / Cloning and expression of the chicken CD18 cDNA by Bilsland (1994)
  6. Brunger, A.T., Adams, P.D., Clore, G.M., DeLano, W.L., Gros, P., GrosseKunstleve, R.W., Jiang, J.S., Kuszewski, J., Nilges, M., Pannu, N.S., et al. (1998). Crystallography and NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr. D54, 905–921. (10.1107/S0907444998003254)
  7. 10.1074/jbc.274.40.28071 / J. Biol. Chem. / The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation by Calderwood (1999)
  8. Dembo, M., Torney, D.C., Saxman, K., and Hammer, D. (1988). The reaction-limited kinetics of membrane-to-surface adhesion and detachment. Proc. R. Soc. Lond. B234, 55–83. (10.1098/rspb.1988.0038)
  9. 10.1074/jbc.272.12.7661 / J. Biol. Chem. / Contributions of the I and EF hand domains to the divalent cation-dependent collagen binding acitivity of the α2β1 integrin by Dickeson (1997)
  10. 10.1021/bi9727848 / Biochemistry / Ligand binding results in divalent cation displacement from the α2β1 integrin I domain by Dickeson (1998)
  11. 10.1074/jbc.270.21.12635 / J. Biol. Chem. / Identification of amino acids in the CD11a I-domain important for binding of the leukocyte function-associated antigen-1 (LFA-1) to intercellular adhesion molecule-1 (ICAM-1) by Edwards (1995)
  12. {'key': '10.1016/S0092-8674(00)80622-4_BIB12', 'first-page': '28937', 'article-title': 'Mapping the intercellular adhesion molecule-1 and -2 binding site on the inserted domain of leukocyte function-associated antigen-1', 'volume': '273', 'author': 'Edwards', 'year': '1998', 'journal-title': '.'} / . / Mapping the intercellular adhesion molecule-1 and -2 binding site on the inserted domain of leukocyte function-associated antigen-1 by Edwards (1998)
  13. 10.1074/jbc.272.45.28512 / J. Biol. Chem. / Crystal structure of the I domain from integrin α2β1 by Emsley (1997)
  14. 10.1074/jbc.273.17.10396 / J. Biol Chem. / Crystal structure of the von Willebrand Factor A1 domain and implications for the binding of glycoprotein Ib by Emsley (1998)
  15. 10.1021/bi9702187 / Biochemistry / Integrin αIIbβ3 reconstituted into lipid bilayers is non-clustered in its activated state but clusters after fibrinogen binding by Erb (1997)
  16. 10.1021/bi9907680 / Biochemistry / Effects of ligand-mimetic peptides Arg-Gly-Asp-X (X = Phe, Trp, Ser) on alpha IIb beta 3 integrin conformation and oligomerization by Hantgan (1999)
  17. 10.1074/jbc.270.32.19008 / J. Biol. Chem. / A binding interface on the I domain of lymphocyte function associated antigen-1 (LFA-1) required for specific interaction with intercellular adhesion molecule 1 (ICAM-1) by Huang (1995)
  18. 10.1073/pnas.94.7.3162 / Proc. Natl. Acad. Sci. USA / Folding of the b-propeller domain of the integrin aL subunit is independent of the I domain and dependent on the b2 subunit by Huang (1997)
  19. 10.1073/pnas.94.7.3156 / Proc. Natl. Acad. Sci. USA / Folding of the conserved domain but not of flanking regions in the integrin b2 subunit requires association with the a-subunit by Huang (1997)
  20. 10.1074/jbc.271.12.6571 / J. Biol. Chem. / Breaking the integrin hinge by Hughes (1996)
  21. 10.1016/0092-8674(92)90115-S / Cell / Integrins by Hynes (1992)
  22. 10.1074/jbc.273.24.14827 / J. Biol. Chem. / Platelets interact with soluble and insoluble collagens through characteristically different reactions by Jung (1998)
  23. 10.1042/bj3160001 / Biochem. J. / Collagen fibril formation by Kadler (1996)
  24. 10.1006/jmbi.1999.3047 / J. Mol. Biol. / Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain by Kallen (1999)
  25. 10.1016/S0021-9258(18)47151-7 / J. Biol. Chem. / Direct binding of collagen to the I-domain of integrin α2β1 (VLA-2, CD49b/CD29) in a divalent cation-independent manner by Kamata (1994)
  26. 10.1016/S0021-9258(17)36932-6 / J. Biol. Chem. / Identification of putative ligand binding sites within I domain of integrin α2β1 (VLA-2, CD49b/CD29) by Kamata (1994)
  27. 10.1074/jbc.274.45.32108 / J. Biol. Chem. / Interaction between collagen and the alpha(2) I-domain of integrin α2β1—critical role of conserved residues in the metal ion-dependent adhesion site (MIDAS) region by Kamata (1999)
  28. 10.1083/jcb.137.6.1433 / J. Cell Biol. / Affinity modulation of platelet integrin alphaIIbbeta3 by beta3-endonexin, a selective binding partner of the beta3 integrin cytoplasmic tail by Kashiwagi (1997)
  29. 10.1016/S0021-9258(17)31717-9 / J. Biol. Chem. / The role of the I domain in ligand binding of the human integrin α1β1 by Kern (1994)
  30. 10.1074/jbc.275.1.35 / J. Biol. Chem. / The collagen-binding A-domains of integrins α1β1 and α2β1 recognize the same specific amino acid sequence, GFOGER, in native (triple-helical) collagens by Knight (2000)
  31. 10.1016/S0092-8674(00)80095-1 / Cell / Alpha L beta 2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule by Kolanus (1996)
  32. 10.1038/8259 / Nat. Struct. Biol. / Sequence dependent conformational variations of collagen triple-helical structure by Kramer (1999)
  33. 10.1107/S0021889891004399 / J. Appl. Crystallogr. / Molscript—a program to produce both detailed and schematic plots of protein structures by Kraulis (1991)
  34. 10.1016/0092-8674(95)90517-0 / Cell / Crystal structure of the A-domain from the the α subunit of integrin CR3 (CD11b/CD18) by Lee (1995)
  35. 10.1016/S0969-2126(01)00271-4 / Structure / Two conformations of the integrin A-domain (I-domain) by Lee (1995)
  36. 10.1083/jcb.143.6.1523 / J. Cell Biol. / Two functional states of the CD11b A-domain by Li (1998)
  37. 10.1016/S0969-2126(98)00094-X / Structure / The integrin I domain by Liddington (1998)
  38. 10.1172/JCI119408 / J. Clin. Invest. / New insights into integrin-ligand interaction by Loftus (1997)
  39. 10.1006/jsbi.1999.4094 / J. Struct. Biol. / XtalView Xfit—a versatile program for manipulating atomic coordinates and electron density by McRee (1999)
  40. Merrit, E.A., and Murphy, M.E.P. (1994). Raster3D version 2.0. A program for photorealistic molecular graphics. Acta Crystallogr. D50, 869–873. (10.1107/S0907444994006396)
  41. 10.1016/0092-8674(93)90575-B / Cell / A novel divalent cation-binding site in the A domain of the β2 intergin CR3 (CD11b/CD18) is essential for ligand binding by Michishita (1993)
  42. 10.1042/bj2990791 / Biochem. J. / Conformation-dependent platelet adhesion to collagen involving integrin α2β1-mediated and other mechanisms—multiple α2β1 recognition sites in collagen type-I by Morton (1994)
  43. 10.1074/jbc.272.28.17283 / J. Biol. Chem. / Defining the topology of integrin α5β1-fibronectin interactions using inhibitory anti-α5 and anti-β1 monoclonal antibodies—evidence that the synergy sequence of fibronectin is recognized by the amino-terminal repeats of the α5 subunit by Mould (1997)
  44. 10.1074/jbc.273.8.4338 / J. Biol. Chem. / Platelet adhesion to native type I collagen fibrils—role of GPVI in divalent cation-dependent and -independent adhesion and thromboxane A(2) generation by Nakamura (1998)
  45. Navaza, J. (1994). AMORE—an atomated molecular replacement program package. Acta Crystallogr. A50, 157–163. (10.1107/S0108767393007597)
  46. {'key': '10.1016/S0092-8674(00)80622-4_BIB46', 'series-title': 'GRASP', 'author': 'Nicholls', 'year': '1992'} / GRASP by Nicholls (1992)
  47. 10.1016/S0014-5793(99)00666-3 / FEBS Lett. / Crystal structure of the alpha 1 beta 1 integrin I-domain by Nolte (1999)
  48. 10.1083/jcb.124.6.1047 / J. Cell Biol. / Integrin cytoplasmic domains mediate inside-out signal transduction by O'Toole (1994)
  49. Otwinowski, Z. (1993). In Data Collection and Processing, L. Sawyer, N. Isaacs, and S. Bailey, eds. (Daresbury, UK: SERC), pp. 59–62.
  50. 10.1073/pnas.96.5.2215 / Proc. Natl. Acad. Sci. USA / Conformational changes in tertiary structure near the ligand binding site of an integrin I domain by Oxvig (1999)
  51. 10.1016/S0969-2126(96)00100-1 / Structure / The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin by Qu (1996)
  52. 10.1074/jbc.274.35.24906 / J. Biol. Chem. / Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, α1β1 integrin and Staphylococcus aureus Cna MSCRAMM by Rich (1999)
  53. 10.1055/s-0038-1642670 / Thrombos. Haemostasis / Molecular mechanism and classification of von Willebrand disease by Sadler (1995)
  54. 10.1055/s-0038-1657565 / Thrombos. Haemostasis / Platelet adhesion to collagen by Sixma (1997)
  55. 10.1074/jbc.275.6.4205 / J. Biol. Chem. / Mapping the collagen binding site in the I domain of the Glycoprotein Ia/IIa (integrin α2β1) by Smith (2000)
  56. 10.1073/pnas.94.1.65 / Proc. Natl. Acad. Sci. USA / Folding of the N-terminal, ligand-binding region of integrin α-subunits into a β-propeller domain by Springer (1997)
  57. 10.1242/jcs.108.4.1629 / J. Cell Sci. / Integrin α2 I-domain is a binding site for collagens by Tuckwell (1995)
  58. 10.1074/jbc.271.47.29953 / J. Biol. Chem. / A discrete site modulates activation of I domains by Zhang (1996)
  59. 10.1074/jbc.272.28.17558 / J. Biol. Chem. / Identification and reconstruction of the binding site with in αMβ2 for a specific and high affinity ligand, NIF by Zhang (1997)
  60. 10.1021/bi990141h / Biochemistry / Amino acid sequences within the a subunit of integrin αMβ2 (Mac-1) critical for specific recognition of C3bi by Zhang (1999)
  61. 10.1042/bj2680481 / Biochem. J. / Platelet adhesion to collagen—factors affecting Mg2+-dependent and bivalent cation-dependent adhesion by Zijenah (1990)
Dates
Type When
Created 21 years, 3 months ago (May 1, 2004, 5:50 a.m.)
Deposited 4 years, 2 months ago (June 17, 2021, 2:02 a.m.)
Indexed 1 week ago (Aug. 24, 2025, 6:59 p.m.)
Issued 25 years, 6 months ago (March 1, 2000)
Published 25 years, 6 months ago (March 1, 2000)
Published Print 25 years, 6 months ago (March 1, 2000)
Funders 0

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@article{Emsley_2000, title={Structural Basis of Collagen Recognition by Integrin α2β1}, volume={101}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/s0092-8674(00)80622-4}, DOI={10.1016/s0092-8674(00)80622-4}, number={1}, journal={Cell}, publisher={Elsevier BV}, author={Emsley, Jonas and Knight, C.Graham and Farndale, Richard W. and Barnes, Michael J. and Liddington, Robert C.}, year={2000}, month=mar, pages={47–56} }