DOI: 10.1016/s0092-8674(00)80118-x. Cdc53 Targets Phosphorylated G1 Cyclins for Degradation by the Ubiquitin Proteolytic Pathway

Cdc53 Targets Phosphorylated G1 Cyclins for Degradation by the Ubiquitin Proteolytic Pathway

10.1016/s0092-8674(00)80118-x

Crossref journal-article

Elsevier BV

Cell (78)

Bibliography

Willems, A. R., Lanker, S., Patton, E. E., Craig, K. L., Nason, T. F., Mathias, N., Kobayashi, R., Wittenberg, C., & Tyers, M. (1996). Cdc53 Targets Phosphorylated G1 Cyclins for Degradation by the Ubiquitin Proteolytic Pathway. Cell, 86(3), 453â463.

Authors 9

Andrew R Willems (first)
Stefan Lanker (additional)
E.Elizabeth Patton (additional)
Karen L Craig (additional)
Timothy F Nason (additional)
Neal Mathias (additional)
Ryuji Kobayashi (additional)
Curt Wittenberg (additional)
Mike Tyers (additional)

References 59 Referenced 227

10.1016/0092-8674(94)90443-X / Cell / Closing the cell cycle circle in yeast by Amon (1994)
10.1016/S0092-8674(00)80098-7 / Cell / SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box by Bai (1996)
10.1038/371339a0 / Nature / Repression of growth-regulated G1 cyclin expression by cyclic AMP in budding yeast by Baroni (1994)
10.1101/gad.9.4.399 / Genes Dev. / G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast by Barral (1995)
10.1126/science.2538923 / Science / A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein by Chau (1989)
10.1128/MCB.8.11.4675 / Mol. Cell. Biol. / DAF1, a mutant gene affecting size control, pheromone arrest, and cell cycle kinetics of Saccharomyces cerevisiae by Cross (1988)
10.1016/0955-0674(95)80062-X / Curr. Opin. Cell Biol. / Starting the cell cycle by Cross (1995)
10.1002/j.1460-2075.1995.tb07004.x / EMBO J. / Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway by Deshaies (1995)
10.1002/j.1460-2075.1995.tb00162.x / EMBO J. / Roles and regulation of Cln-Cdc28 kinases at the start of the cell cycle of Saccharomyces cerevisiae by Dirick (1995)
10.1016/0092-8674(83)90420-8 / Cell / Cyclin by Evans (1983)
10.1091/mbc.3.7.805 / Mol. Biol. Cell / Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae by Fitch (1992)
10.1038/349132a0 / Nature / Cyclin is degraded by the ubiquitin pathway by Glotzer (1991)
10.1126/science.2842867 / Science / The yeast cell cycle gene CDC34 encodes a ubiquitin-conjugating enzyme by Goebl (1988)
10.1128/MCB.9.5.2034 / Mol. Cell. Biol. / The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex by Hadwiger (1989)
10.1073/pnas.86.16.6255 / Proc. Natl. Acad. Sci. USA / A family of cyclin homologs that control the G1 phase in yeast by Hadwiger (1989)
{'key': '10.1016/S0092-8674(00)80118-X_BIB16', 'series-title': 'Antibodies', 'author': 'Harlow', 'year': '1988'} / Antibodies by Harlow (1988)
10.1016/S0021-9258(17)37636-6 / J. Biol. Chem. / Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase Cdc2 by Hershko (1994)
10.1016/0955-0674(95)80031-X / Curr. Opin. Cell Biol. / Ubiquitin, proteasomes, and the regulation of intracellular protein degradation by Hochstrasser (1995)
10.1016/S0021-9258(19)50351-9 / J. Biol. Chem. / Expression of a ubiquitin derivative that conjugates to protein irreversibly produces phenotypes consistent with a ubiquitin deficiency by Hodgins (1992)
10.1073/pnas.92.7.2563 / Proc. Natl. Acad. Sci. USA / A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase by Huibregtse (1995)
10.1016/0092-8674(94)90543-6 / Cell / Cyclins and cancer. II. Cyclin D and CDK inhibitors come of age by Hunter (1994)
10.1016/0092-8674(95)90337-2 / Cell / Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast by Irniger (1995)
{'key': '10.1016/S0092-8674(00)80118-X_BIB23', 'series-title': 'Methods in Yeast Genetics', 'author': 'Kaiser', 'year': '1994'} / Methods in Yeast Genetics by Kaiser (1994)
10.1016/0092-8674(95)90338-0 / Cell / A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B by King (1995)
10.1016/S0092-8674(00)81267-2 / Cell / cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family by Kipreos (1996)
10.1016/0076-6879(91)94038-E / Meth. Enzymol. / Epitope tagging and protein surveillance by Kolodziej (1991)
10.1002/j.1460-2075.1994.tb06948.x / EMBO J. / Regulated degradation of the transcription factor Gcn4 by Kornitzer (1994)
10.1126/science.271.5255.1597 / Science / Rapid degradation of the G1 cyclin Cln2 induced by CDK-dependent phosphorylation by Lanker (1996)
10.1016/0092-8674(91)90042-W / Cell / Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast by Lew (1991)
10.1016/S0021-9258(19)50306-4 / J. Biol. Chem. / N-recognin/Ubc2 interactions in the N-end rule pathway by Madura (1993)
10.1101/gad.7.5.833 / Genes Dev. / Negative regulation of FAR1 at the Start of the yeast cell cycle by McKinney (1993)
10.1126/science.8421781 / Science / An inhibitor of p34CDC28 protein kinase activity from Saccharomyces cerevisiae by Mendenhall (1993)
10.1016/0092-8674(95)90322-4 / Cell / Cyclin ubiquitination by Murray (1995)
10.1002/j.1460-2075.1988.tb03332.x / EMBO J. / The WHI1+ gene of Saccharomyces cerevisiae tethers cell division to cell size and is a cyclin homolog by Nash (1988)
10.1016/0955-0674(93)90099-C / Curr. Opin. Cell Biol. / Control of the yeast cell cycle by the Cdc28 protein kinase by Nasmyth (1993)
10.1128/MCB.14.5.3320 / Mol. Cell. Biol. / An inhibitor of yeast cyclin-dependent protein kinase plays an important role in ensuring the genomic integrity of daughter cells by Nugroho (1994)
10.1016/S0065-230X(08)60254-7 / Adv. Cancer Res. / Cyclins and cyclin-dependent kinases by Pines (1995)
10.1101/gad.6.11.2021 / Genes Dev. / Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2 by Richardson (1992)
10.1126/science.2876518 / Science / Amino acid sequences common to rapidly degraded proteins by Rogers (1986)
10.1128/MCB.14.12.7953 / Mol. Cell. Biol. / G1 cyclin degradation by Salama (1994)
10.1038/373081a0 / Nature / Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade by Scheffner (1995)
10.1002/yea.320111306 / Yeast / Use of polymerase chain reaction epitope tagging for protein tagging in Saccharomyces cerevisiae by Schneider (1995)
10.1126/science.272.5261.560 / Science / Linkage of replication to Start by the Cdk inhibitor Sic1 by Schneider (1996)
10.1073/pnas.88.3.1004 / Proc. Natl. Acad. Sci. USA / Specific initiation by RNA polymerase I in a whole-cell extract from yeast by Schultz (1991)
10.1101/gad.7.7a.1160 / Genes Dev. / CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae by Schwob (1993)
10.1016/0092-8674(94)90193-7 / Cell / The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae by Schwob (1994)
10.1016/0092-8674(94)90540-1 / Cell / G1 phase progression by Sherr (1994)
10.1093/genetics/122.1.19 / Genetics / A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae by Sikorski (1989)
10.1016/S0021-9258(17)39255-4 / J. Biol. Chem. / Isolation of three proteins that bind to mammalian RNA polymerase II by Sopta (1985)
10.1101/gad.9.22.2780 / Genes Dev. / CLN3, not positive feedback, determines the timing of CLN2 transcription in cycling cells by Stuart (1995)
10.1091/mbc.6.2.185 / Mol. Biol. Cell / The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis by Sudakin (1995)
10.1038/371342a0 / Nature / Inhibition of G1 cyclin activity by the Ras/cAMP pathway in yeast by Tokiwa (1994)
10.1073/pnas.93.15.7772 / Proc. Natl. Acad. Sci. USA, in press. / The cyclin-dependent kinase inhibitor p40SIC1 imposes the requirement for CLN G1 cyclin function at Start by Tyers (1996)
10.1002/j.1460-2075.1992.tb05229.x / EMBO J. / The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation by Tyers (1992)
10.1002/j.1460-2075.1993.tb05845.x / EMBO J. / Comparison of the Saccharomyces cerevisiae G1 cyclins by Tyers (1993)
{'issue': 'CDC28 protein kinase. Cell 62', 'key': '10.1016/S0092-8674(00)80118-X_BIB56', 'first-page': '225', 'article-title': 'G1-specific cyclins of S', 'volume': 'p.34', 'author': 'Wittenberg', 'year': '1990', 'journal-title': 'cerevisiae'} / cerevisiae / G1-specific cyclins of S by Wittenberg (1990)
10.1128/MCB.15.2.731 / Mol. Cell. Biol. / p34CDC28-mediated control of Cln3 cyclin degradation by Yaglom (1995)
10.1016/0022-2836(87)90646-2 / J. Mol. Biol. / Structural comparison of the yeast cell division cycle gene CDC4 and a related pseudogene by Yochem (1987)
10.1128/MCB.15.9.4835 / Mol. Cell. Biol. / Genetic and biochemical interactions between an essential kinetochore protein, Cbf2p/Ndc10p, and the CDC34 ubiquitin-conjugating enzyme by Yoon (1995)

Dates

Type	When
Created	21 years, 2 months ago (June 9, 2004, 4:23 p.m.)
Deposited	4 years, 2 months ago (June 22, 2021, 11:46 p.m.)
Indexed	1 month, 1 week ago (July 14, 2025, 11:21 p.m.)
Issued	29 years ago (Aug. 1, 1996)
Published	29 years ago (Aug. 1, 1996)
Published Print	29 years ago (Aug. 1, 1996)

Funders 0

None

BibTeX

@article{Willems_1996, title={Cdc53 Targets Phosphorylated G1 Cyclins for Degradation by the Ubiquitin Proteolytic Pathway}, volume={86}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/s0092-8674(00)80118-x}, DOI={10.1016/s0092-8674(00)80118-x}, number={3}, journal={Cell}, publisher={Elsevier BV}, author={Willems, Andrew R and Lanker, Stefan and Patton, E.Elizabeth and Craig, Karen L and Nason, Timothy F and Mathias, Neal and Kobayashi, Ryuji and Wittenberg, Curt and Tyers, Mike}, year={1996}, month=aug, pages={453–463} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        7,
        15
      ]
    ],
    "date-time": "2025-07-15T03:21:12Z",
    "timestamp": 1752549672887
  },
  "reference-count": 59,
  "publisher": "Elsevier BV",
  "issue": "3",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            1996,
            8,
            1
          ]
        ],
        "date-time": "1996-08-01T00:00:00Z",
        "timestamp": 838857600000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    },
    {
      "start": {
        "date-parts": [
          [
            2013,
            7,
            17
          ]
        ],
        "date-time": "2013-07-17T00:00:00Z",
        "timestamp": 1374019200000
      },
      "content-version": "vor",
      "delay-in-days": 6194,
      "URL": "https://www.elsevier.com/open-access/userlicense/1.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1996,
        8
      ]
    ]
  },
  "DOI": "10.1016/s0092-8674(00)80118-x",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2004,
        6,
        9
      ]
    ],
    "date-time": "2004-06-09T20:23:03Z",
    "timestamp": 1086812583000
  },
  "page": "453-463",
  "source": "Crossref",
  "is-referenced-by-count": 227,
  "title": "Cdc53 Targets Phosphorylated G1 Cyclins for Degradation by the Ubiquitin Proteolytic Pathway",
  "prefix": "10.1016",
  "volume": "86",
  "author": [
    {
      "given": "Andrew R",
      "family": "Willems",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Stefan",
      "family": "Lanker",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "E.Elizabeth",
      "family": "Patton",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Karen L",
      "family": "Craig",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Timothy F",
      "family": "Nason",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Neal",
      "family": "Mathias",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Ryuji",
      "family": "Kobayashi",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Curt",
      "family": "Wittenberg",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Mike",
      "family": "Tyers",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB1",
      "doi-asserted-by": "crossref",
      "first-page": "1037",
      "DOI": "10.1016/0092-8674(94)90443-X",
      "article-title": "Closing the cell cycle circle in yeast",
      "volume": "77",
      "author": "Amon",
      "year": "1994",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB2",
      "doi-asserted-by": "crossref",
      "first-page": "263",
      "DOI": "10.1016/S0092-8674(00)80098-7",
      "article-title": "SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box",
      "volume": "86",
      "author": "Bai",
      "year": "1996",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB3",
      "doi-asserted-by": "crossref",
      "first-page": "339",
      "DOI": "10.1038/371339a0",
      "article-title": "Repression of growth-regulated G1 cyclin expression by cyclic AMP in budding yeast",
      "volume": "371",
      "author": "Baroni",
      "year": "1994",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB4",
      "doi-asserted-by": "crossref",
      "first-page": "399",
      "DOI": "10.1101/gad.9.4.399",
      "article-title": "G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast",
      "volume": "9",
      "author": "Barral",
      "year": "1995",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB5",
      "doi-asserted-by": "crossref",
      "first-page": "1576",
      "DOI": "10.1126/science.2538923",
      "article-title": "A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein",
      "volume": "243",
      "author": "Chau",
      "year": "1989",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB6",
      "doi-asserted-by": "crossref",
      "first-page": "4675",
      "DOI": "10.1128/MCB.8.11.4675",
      "article-title": "DAF1, a mutant gene affecting size control, pheromone arrest, and cell cycle kinetics of Saccharomyces cerevisiae",
      "volume": "8",
      "author": "Cross",
      "year": "1988",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB7",
      "doi-asserted-by": "crossref",
      "first-page": "790",
      "DOI": "10.1016/0955-0674(95)80062-X",
      "article-title": "Starting the cell cycle",
      "volume": "7",
      "author": "Cross",
      "year": "1995",
      "journal-title": "Curr. Opin. Cell Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB8",
      "doi-asserted-by": "crossref",
      "first-page": "303",
      "DOI": "10.1002/j.1460-2075.1995.tb07004.x",
      "article-title": "Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway",
      "volume": "14",
      "author": "Deshaies",
      "year": "1995",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB9",
      "doi-asserted-by": "crossref",
      "first-page": "4803",
      "DOI": "10.1002/j.1460-2075.1995.tb00162.x",
      "article-title": "Roles and regulation of Cln-Cdc28 kinases at the start of the cell cycle of Saccharomyces cerevisiae",
      "volume": "14",
      "author": "Dirick",
      "year": "1995",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB10",
      "doi-asserted-by": "crossref",
      "first-page": "389",
      "DOI": "10.1016/0092-8674(83)90420-8",
      "article-title": "Cyclin",
      "volume": "33",
      "author": "Evans",
      "year": "1983",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB11",
      "doi-asserted-by": "crossref",
      "first-page": "805",
      "DOI": "10.1091/mbc.3.7.805",
      "article-title": "Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae",
      "volume": "3",
      "author": "Fitch",
      "year": "1992",
      "journal-title": "Mol. Biol. Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB12",
      "doi-asserted-by": "crossref",
      "first-page": "132",
      "DOI": "10.1038/349132a0",
      "article-title": "Cyclin is degraded by the ubiquitin pathway",
      "volume": "349",
      "author": "Glotzer",
      "year": "1991",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB13",
      "doi-asserted-by": "crossref",
      "first-page": "1331",
      "DOI": "10.1126/science.2842867",
      "article-title": "The yeast cell cycle gene CDC34 encodes a ubiquitin-conjugating enzyme",
      "volume": "241",
      "author": "Goebl",
      "year": "1988",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB14",
      "doi-asserted-by": "crossref",
      "first-page": "2034",
      "DOI": "10.1128/MCB.9.5.2034",
      "article-title": "The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex",
      "volume": "9",
      "author": "Hadwiger",
      "year": "1989",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB15",
      "doi-asserted-by": "crossref",
      "first-page": "6255",
      "DOI": "10.1073/pnas.86.16.6255",
      "article-title": "A family of cyclin homologs that control the G1 phase in yeast",
      "volume": "86",
      "author": "Hadwiger",
      "year": "1989",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB16",
      "series-title": "Antibodies",
      "author": "Harlow",
      "year": "1988"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB17",
      "doi-asserted-by": "crossref",
      "first-page": "4940",
      "DOI": "10.1016/S0021-9258(17)37636-6",
      "article-title": "Components of a system that ligates cyclin to ubiquitin and their regulation by the protein kinase Cdc2",
      "volume": "269",
      "author": "Hershko",
      "year": "1994",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "215",
      "DOI": "10.1016/0955-0674(95)80031-X",
      "article-title": "Ubiquitin, proteasomes, and the regulation of intracellular protein degradation",
      "volume": "7",
      "author": "Hochstrasser",
      "year": "1995",
      "journal-title": "Curr. Opin. Cell Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "8807",
      "DOI": "10.1016/S0021-9258(19)50351-9",
      "article-title": "Expression of a ubiquitin derivative that conjugates to protein irreversibly produces phenotypes consistent with a ubiquitin deficiency",
      "volume": "267",
      "author": "Hodgins",
      "year": "1992",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB20",
      "doi-asserted-by": "crossref",
      "first-page": "2563",
      "DOI": "10.1073/pnas.92.7.2563",
      "article-title": "A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase",
      "volume": "92",
      "author": "Huibregtse",
      "year": "1995",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "573",
      "DOI": "10.1016/0092-8674(94)90543-6",
      "article-title": "Cyclins and cancer. II. Cyclin D and CDK inhibitors come of age",
      "volume": "79",
      "author": "Hunter",
      "year": "1994",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "269",
      "DOI": "10.1016/0092-8674(95)90337-2",
      "article-title": "Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast",
      "volume": "81",
      "author": "Irniger",
      "year": "1995",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB23",
      "series-title": "Methods in Yeast Genetics",
      "author": "Kaiser",
      "year": "1994"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "279",
      "DOI": "10.1016/0092-8674(95)90338-0",
      "article-title": "A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B",
      "volume": "81",
      "author": "King",
      "year": "1995",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "829",
      "DOI": "10.1016/S0092-8674(00)81267-2",
      "article-title": "cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family",
      "volume": "85",
      "author": "Kipreos",
      "year": "1996",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "508",
      "DOI": "10.1016/0076-6879(91)94038-E",
      "article-title": "Epitope tagging and protein surveillance",
      "volume": "194",
      "author": "Kolodziej",
      "year": "1991",
      "journal-title": "Meth. Enzymol."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "6021",
      "DOI": "10.1002/j.1460-2075.1994.tb06948.x",
      "article-title": "Regulated degradation of the transcription factor Gcn4",
      "volume": "13",
      "author": "Kornitzer",
      "year": "1994",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "1597",
      "DOI": "10.1126/science.271.5255.1597",
      "article-title": "Rapid degradation of the G1 cyclin Cln2 induced by CDK-dependent phosphorylation",
      "volume": "271",
      "author": "Lanker",
      "year": "1996",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "1197",
      "DOI": "10.1016/0092-8674(91)90042-W",
      "article-title": "Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast",
      "volume": "66",
      "author": "Lew",
      "year": "1991",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "12046",
      "DOI": "10.1016/S0021-9258(19)50306-4",
      "article-title": "N-recognin/Ubc2 interactions in the N-end rule pathway",
      "volume": "268",
      "author": "Madura",
      "year": "1993",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "833",
      "DOI": "10.1101/gad.7.5.833",
      "article-title": "Negative regulation of FAR1 at the Start of the yeast cell cycle",
      "volume": "7",
      "author": "McKinney",
      "year": "1993",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "216",
      "DOI": "10.1126/science.8421781",
      "article-title": "An inhibitor of p34CDC28 protein kinase activity from Saccharomyces cerevisiae",
      "volume": "259",
      "author": "Mendenhall",
      "year": "1993",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "149",
      "DOI": "10.1016/0092-8674(95)90322-4",
      "article-title": "Cyclin ubiquitination",
      "volume": "81",
      "author": "Murray",
      "year": "1995",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "4335",
      "DOI": "10.1002/j.1460-2075.1988.tb03332.x",
      "article-title": "The WHI1+ gene of Saccharomyces cerevisiae tethers cell division to cell size and is a cyclin homolog",
      "volume": "7",
      "author": "Nash",
      "year": "1988",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "166",
      "DOI": "10.1016/0955-0674(93)90099-C",
      "article-title": "Control of the yeast cell cycle by the Cdc28 protein kinase",
      "volume": "5",
      "author": "Nasmyth",
      "year": "1993",
      "journal-title": "Curr. Opin. Cell Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "3320",
      "DOI": "10.1128/MCB.14.5.3320",
      "article-title": "An inhibitor of yeast cyclin-dependent protein kinase plays an important role in ensuring the genomic integrity of daughter cells",
      "volume": "14",
      "author": "Nugroho",
      "year": "1994",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "181",
      "DOI": "10.1016/S0065-230X(08)60254-7",
      "article-title": "Cyclins and cyclin-dependent kinases",
      "volume": "66",
      "author": "Pines",
      "year": "1995",
      "journal-title": "Adv. Cancer Res."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "2021",
      "DOI": "10.1101/gad.6.11.2021",
      "article-title": "Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2",
      "volume": "6",
      "author": "Richardson",
      "year": "1992",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "364",
      "DOI": "10.1126/science.2876518",
      "article-title": "Amino acid sequences common to rapidly degraded proteins",
      "volume": "234",
      "author": "Rogers",
      "year": "1986",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "7953",
      "DOI": "10.1128/MCB.14.12.7953",
      "article-title": "G1 cyclin degradation",
      "volume": "14",
      "author": "Salama",
      "year": "1994",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "81",
      "DOI": "10.1038/373081a0",
      "article-title": "Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade",
      "volume": "373",
      "author": "Scheffner",
      "year": "1995",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "1265",
      "DOI": "10.1002/yea.320111306",
      "article-title": "Use of polymerase chain reaction epitope tagging for protein tagging in Saccharomyces cerevisiae",
      "volume": "11",
      "author": "Schneider",
      "year": "1995",
      "journal-title": "Yeast"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "560",
      "DOI": "10.1126/science.272.5261.560",
      "article-title": "Linkage of replication to Start by the Cdk inhibitor Sic1",
      "volume": "272",
      "author": "Schneider",
      "year": "1996",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "1004",
      "DOI": "10.1073/pnas.88.3.1004",
      "article-title": "Specific initiation by RNA polymerase I in a whole-cell extract from yeast",
      "volume": "88",
      "author": "Schultz",
      "year": "1991",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "1160",
      "DOI": "10.1101/gad.7.7a.1160",
      "article-title": "CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae",
      "volume": "7",
      "author": "Schwob",
      "year": "1993",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "233",
      "DOI": "10.1016/0092-8674(94)90193-7",
      "article-title": "The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae",
      "volume": "79",
      "author": "Schwob",
      "year": "1994",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "551",
      "DOI": "10.1016/0092-8674(94)90540-1",
      "article-title": "G1 phase progression",
      "volume": "79",
      "author": "Sherr",
      "year": "1994",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "19",
      "DOI": "10.1093/genetics/122.1.19",
      "article-title": "A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae",
      "volume": "122",
      "author": "Sikorski",
      "year": "1989",
      "journal-title": "Genetics"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "10353",
      "DOI": "10.1016/S0021-9258(17)39255-4",
      "article-title": "Isolation of three proteins that bind to mammalian RNA polymerase II",
      "volume": "260",
      "author": "Sopta",
      "year": "1985",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB50",
      "doi-asserted-by": "crossref",
      "first-page": "2780",
      "DOI": "10.1101/gad.9.22.2780",
      "article-title": "CLN3, not positive feedback, determines the timing of CLN2 transcription in cycling cells",
      "volume": "9",
      "author": "Stuart",
      "year": "1995",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB51",
      "doi-asserted-by": "crossref",
      "first-page": "185",
      "DOI": "10.1091/mbc.6.2.185",
      "article-title": "The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis",
      "volume": "6",
      "author": "Sudakin",
      "year": "1995",
      "journal-title": "Mol. Biol. Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB52",
      "doi-asserted-by": "crossref",
      "first-page": "342",
      "DOI": "10.1038/371342a0",
      "article-title": "Inhibition of G1 cyclin activity by the Ras/cAMP pathway in yeast",
      "volume": "371",
      "author": "Tokiwa",
      "year": "1994",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB53",
      "doi-asserted-by": "crossref",
      "DOI": "10.1073/pnas.93.15.7772",
      "article-title": "The cyclin-dependent kinase inhibitor p40SIC1 imposes the requirement for CLN G1 cyclin function at Start",
      "author": "Tyers",
      "year": "1996",
      "journal-title": "Proc. Natl. Acad. Sci. USA, in press."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB54",
      "doi-asserted-by": "crossref",
      "first-page": "1773",
      "DOI": "10.1002/j.1460-2075.1992.tb05229.x",
      "article-title": "The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation",
      "volume": "11",
      "author": "Tyers",
      "year": "1992",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB55",
      "doi-asserted-by": "crossref",
      "first-page": "1955",
      "DOI": "10.1002/j.1460-2075.1993.tb05845.x",
      "article-title": "Comparison of the Saccharomyces cerevisiae G1 cyclins",
      "volume": "12",
      "author": "Tyers",
      "year": "1993",
      "journal-title": "EMBO J."
    },
    {
      "issue": "CDC28 protein kinase. Cell 62",
      "key": "10.1016/S0092-8674(00)80118-X_BIB56",
      "first-page": "225",
      "article-title": "G1-specific cyclins of S",
      "volume": "p.34",
      "author": "Wittenberg",
      "year": "1990",
      "journal-title": "cerevisiae"
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB57",
      "doi-asserted-by": "crossref",
      "first-page": "731",
      "DOI": "10.1128/MCB.15.2.731",
      "article-title": "p34CDC28-mediated control of Cln3 cyclin degradation",
      "volume": "15",
      "author": "Yaglom",
      "year": "1995",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB58",
      "doi-asserted-by": "crossref",
      "first-page": "233",
      "DOI": "10.1016/0022-2836(87)90646-2",
      "article-title": "Structural comparison of the yeast cell division cycle gene CDC4 and a related pseudogene",
      "volume": "195",
      "author": "Yochem",
      "year": "1987",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)80118-X_BIB59",
      "doi-asserted-by": "crossref",
      "first-page": "4835",
      "DOI": "10.1128/MCB.15.9.4835",
      "article-title": "Genetic and biochemical interactions between an essential kinetochore protein, Cbf2p/Ndc10p, and the CDC34 ubiquitin-conjugating enzyme",
      "volume": "15",
      "author": "Yoon",
      "year": "1995",
      "journal-title": "Mol. Cell. Biol."
    }
  ],
  "container-title": "Cell",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S009286740080118X?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S009286740080118X?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2021,
        6,
        23
      ]
    ],
    "date-time": "2021-06-23T03:46:55Z",
    "timestamp": 1624420015000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S009286740080118X"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1996,
        8
      ]
    ]
  },
  "references-count": 59,
  "journal-issue": {
    "issue": "3",
    "published-print": {
      "date-parts": [
        [
          1996,
          8
        ]
      ]
    }
  },
  "alternative-id": [
    "S009286740080118X"
  ],
  "URL": "http://dx.doi.org/10.1016/S0092-8674(00)80118-X",
  "relation": {},
  "ISSN": [
    "0092-8674"
  ],
  "subject": [],
  "container-title-short": "Cell",
  "published": {
    "date-parts": [
      [
        1996,
        8
      ]
    ]
  }
}