Crossref journal-article
Elsevier BV
Cell (78)
Bibliography

Porter, J. A., Ekker, S. C., Park, W.-J., von Kessler, D. P., Young, K. E., Chen, C.-H., Ma, Y., Woods, A. S., Cotter, R. J., Koonin, E. V., & Beachy, P. A. (1996). Hedgehog Patterning Activity: Role of a Lipophilic Modification Mediated by the Carboxy-Terminal Autoprocessing Domain. Cell, 86(1), 21–34.

Authors 11
  1. Jeffery A Porter (first)
  2. Stephen C Ekker (additional)
  3. Woo-Jin Park (additional)
  4. Doris P von Kessler (additional)
  5. Keith E Young (additional)
  6. Chien-Huan Chen (additional)
  7. Yong Ma (additional)
  8. Amina S Woods (additional)
  9. Robert J Cotter (additional)
  10. Eugene V Koonin (additional)
  11. Philip A Beachy (additional)
References 37 Referenced 434
  1. {'key': '10.1016/S0092-8674(00)80074-4_BIB1', 'series-title': 'Molecular Biology of the Cell', 'author': 'Alberts', 'year': '1994'} / Molecular Biology of the Cell by Alberts (1994)
  2. {'key': '10.1016/S0092-8674(00)80074-4_BIB2', 'series-title': 'Current Protocols in Molecular Biology', 'year': '1995'} / Current Protocols in Molecular Biology (1995)
  3. 10.1021/ac00101a009 / Anal. Chem. / Polyethylene membrane as a sample support for direct matrix-assisted laser desorption/ionization mass spectrometric analysis of high mass proteins by Blackledge (1995)
  4. 10.1016/S0021-9258(19)69848-0 / J. Biol. Chem. / Phase separation of integral membrane proteins in Triton X-114 solution by Bordier (1981)
  5. 10.1242/dev.118.2.401 / Development / Targeted gene expression as a means of altering cell fates and generating dominant phenotypes by Brand (1993)
  6. 10.1038/378416a0 / Nature / A protein catalytic framework with an N-terminal nucleophile is capable of self-activation by Brannigan (1995)
  7. 10.1128/MCB.15.4.2294 / Mol. Cell. Biol. / Proteolytic processing yields two secreted forms of sonic hedgehog by Bumcrot (1995)
  8. 10.1038/302349a0 / Nature / The membrane form of variant surface glycoproteins of Trypanosoma brucei by Cardoso de Almeida (1983)
  9. 10.1126/science.7716512 / Science / Protein lipidation in cell signaling by Casey (1995)
  10. {'key': '10.1016/S0092-8674(00)80074-4_BIB10', 'first-page': '5', 'article-title': 'A matrix-assisted laser desorption time-of-flight mass spectrometer based on a 600 ps2 mJ nitrogen laser', 'volume': '1', 'author': 'Chevrier', 'year': '1991', 'journal-title': 'Rapid Commun. Mass Spectrom.'} / Rapid Commun. Mass Spectrom. / A matrix-assisted laser desorption time-of-flight mass spectrometer based on a 600 ps2 mJ nitrogen laser by Chevrier (1991)
  11. {'key': '10.1016/S0092-8674(00)80074-4_BIB11', 'first-page': '792', 'article-title': 'α-2 macroglobulin, complement, and biological defense', 'volume': '71', 'author': 'Chu', 'year': '1994', 'journal-title': 'Lab. Invest.'} / Lab. Invest. / α-2 macroglobulin, complement, and biological defense by Chu (1994)
  12. 10.1016/S0968-0004(00)89075-1 / Trends Biochem. Sci. / Protein splicing by Cooper (1995)
  13. 10.1126/science.7973629 / Science / Synthesis of proteins by native chemical ligation by Dawson (1994)
  14. 10.1021/bi00106a001 / Biochemistry / Membrane proteins with soluble counterparts by Ehlers (1991)
  15. 10.1146/annurev.bi.62.070193.001005 / Annu. Rev. Biochem. / The structure and biosynthesis of glycosyl phosphatidylinositol protein anchors by Englund (1993)
  16. 10.1016/S0960-9822(95)00129-1 / Curr. Biol. / Secretion of the amino-terminal fragment of the Hedgehog protein is necessary and sufficient for hedgehog signalling in Drosophila by Fietz (1995)
  17. 10.1126/science.8456298 / Science / Ancient conserved regions in new gene sequences and the protein databases by Green (1993)
  18. 10.1038/378212a0 / Nature / A potential catalytic site revealed by the 1.7-Å crystal structure of the amino-terminal signalling domain of Sonic hedgehog by Hall (1995)
  19. 10.1016/0092-8674(94)90110-4 / Cell / Drosophila hedgehog acts as a morphogen in cellular patterning by Heemskerk (1994)
  20. 10.1146/annurev.bi.61.070192.003553 / Annu. Rev. Biochem. / The ubiquitin system for protein degradation by Hershko (1992)
  21. 10.1016/S0021-9673(01)87434-3 / J. Chromatogr. / Characterization of a solvent system for separation of water-insoluble poliovirus proteins by reversed-phase high-performance liquid chromatography by Heukeshoven (1985)
  22. 10.1038/366560a0 / Nature / Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo by Ingham (1993)
  23. 10.1016/S0968-0004(00)88989-6 / Trends Biochem. Sci. / A protein splice–junction motif in hedgehog family proteins by Koonin (1995)
  24. 10.1016/S0076-6879(96)66020-0 / Meth. Enzymol. / Protein sequence comparison at a genome scale by Koonin (1996)
  25. 10.1126/science.7985023 / Science / Autoproteolysis in hedgehog protein biogenesis by Lee (1994)
  26. {'key': '10.1016/S0092-8674(00)80074-4_BIB26', 'first-page': '73', 'article-title': 'The thioester bond of C3', 'volume': '153', 'author': 'Levine', 'year': '1990', 'journal-title': 'Curr. Topics Microbiol. Immunol.'} / Curr. Topics Microbiol. Immunol. / The thioester bond of C3 by Levine (1990)
  27. 10.1016/S0968-0004(00)89042-8 / Trends Biochem. Sci. / The myristoyl–electrostatic switch by McLaughlin (1995)
  28. 10.1038/374363a0 / Nature / The product of hedgehog autoproteolytic cleavage active in local and long-range signalling by Porter (1995)
  29. 10.1146/annurev.cb.08.110192.002143 / Annu. Rev. Cell Biol. / Polarity of epithelial and neuronal cells by Rodriguez-Boulan (1992)
  30. 10.1016/0092-8674(95)90397-6 / Cell / Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis by Roelink (1995)
  31. 10.1021/bi00287a012 / Biochemistry / An enzyme with ubiquitin carboxy-terminal esterase activity from reticulocytes by Rose (1983)
  32. {'key': '10.1016/S0092-8674(00)80074-4_BIB32', 'first-page': '353', 'article-title': 'Cell lines derived from late embryonic stages of Drosophila melanogaster', 'volume': '27', 'author': 'Schneider', 'year': '1972', 'journal-title': 'J. Embryol. Exp. Morphol.'} / J. Embryol. Exp. Morphol. / Cell lines derived from late embryonic stages of Drosophila melanogaster by Schneider (1972)
  33. 10.1016/0092-8674(94)90175-9 / Cell / Hedgehog is a signalling protein with a key role in patterning Drosophila imaginal discs by Tabata (1994)
  34. 10.1016/0925-4773(93)90101-3 / Mech. Dev. / Contrasting distributions of patched and hedgehog proteins in the Drosophila embryo by Taylor (1993)
  35. 10.1146/annurev.bi.64.070195.003023 / Annu. Rev. Biochem. / How glycosyl-phosphatidylinositol-anchored membrane proteins are made by Udenfriend (1995)
  36. 10.1146/annurev.bi.59.070190.000333 / Annu. Rev. Biochem. / Pyruvoyl-dependent enzymes by van Poelje (1990)
  37. 10.1093/nar/14.11.4683 / Nucleic Acids Res. / A new method for predicting signal sequence cleavage sites by von Heijne (1986)
Dates
Type When
Created 21 years, 2 months ago (June 23, 2004, 10:58 a.m.)
Deposited 2 years, 7 months ago (Jan. 28, 2023, 8:21 a.m.)
Indexed 3 weeks, 2 days ago (Aug. 5, 2025, 9:11 a.m.)
Issued 29 years, 1 month ago (July 1, 1996)
Published 29 years, 1 month ago (July 1, 1996)
Published Print 29 years, 1 month ago (July 1, 1996)
Funders 0

None

@article{Porter_1996, title={Hedgehog Patterning Activity: Role of a Lipophilic Modification Mediated by the Carboxy-Terminal Autoprocessing Domain}, volume={86}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/s0092-8674(00)80074-4}, DOI={10.1016/s0092-8674(00)80074-4}, number={1}, journal={Cell}, publisher={Elsevier BV}, author={Porter, Jeffery A and Ekker, Stephen C and Park, Woo-Jin and von Kessler, Doris P and Young, Keith E and Chen, Chien-Huan and Ma, Yong and Woods, Amina S and Cotter, Robert J and Koonin, Eugene V and Beachy, Philip A}, year={1996}, month=jul, pages={21–34} }