DOI: 10.1016/s0092-8674(00)00034-9. Mitotic Phosphorylation of Histone H3 Is Governed by Ipl1/aurora Kinase and Glc7/PP1 Phosphatase in Budding Yeast and Nematodes

Mitotic Phosphorylation of Histone H3 Is Governed by Ipl1/aurora Kinase and Glc7/PP1 Phosphatase in Budding Yeast and Nematodes

10.1016/s0092-8674(00)00034-9

Crossref journal-article

Elsevier BV

Cell (78)

Bibliography

Hsu, J.-Y., Sun, Z.-W., Li, X., Reuben, M., Tatchell, K., Bishop, D. K., Grushcow, J. M., Brame, C. J., Caldwell, J. A., Hunt, D. F., Lin, R., Smith, M. M., & Allis, C. D. (2000). Mitotic Phosphorylation of Histone H3 Is Governed by Ipl1/aurora Kinase and Glc7/PP1 Phosphatase in Budding Yeast and Nematodes. Cell, 102(3), 279â291.

Authors 13

Jer-Yuan Hsu (first)
Zu-Wen Sun (additional)
Xiumin Li (additional)
Melanie Reuben (additional)
Kelly Tatchell (additional)
Douglas K Bishop (additional)
Jeremy M Grushcow (additional)
Cynthia J Brame (additional)
Jennifer A Caldwell (additional)
Donald F Hunt (additional)
Rueyling Lin (additional)
M.Mitchell Smith (additional)
C.David Allis (additional)

References 72 Referenced 711

10.1002/j.1460-2075.1986.tb04551.x / EMBO J. / Nuclease hypersensitive regions with adjacent positioned nucleosomes mark the gene boundaries of the PHO5/PHO3 locus in yeast by Almer (1986)
10.1083/jcb.141.5.1207 / J. Cell Biol. / Differential subcellular localization of protein phosphatase-1 alpha, gamma1, and delta isoforms during both interphase and mitosis in mammalian cells by Andreassen (1998)
10.1016/0092-8674(90)90286-N / Cell / One of the protein phosphatase 1 isoenzymes in Drosophila is essential for mitosis by Axton (1990)
10.1093/genetics/145.3.615 / Genetics / Alanine-scanning mutagenesis of protein phosphatase type 1 in the yeast Saccharomyces cerevisiae by Baker (1997)
10.1101/gad.13.5.532 / Genes Dev. / The conserved protein kinase Ipl1 regulates microtubule binding to kinetochores in budding yeast by Biggins (1999)
10.1016/S0962-8924(99)01658-X / Trends Cell Biol. / The Aurora/Ipl1p kinase family by Bischoff (1999)
10.1093/emboj/17.11.3052 / EMBO J. / A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers by Bischoff (1998)
10.1016/0092-8674(94)90038-8 / Cell / RecA homologs Dmc1 and Rad51 interact to form multiple nuclear complexes prior to meiotic chromosome synapsis by Bishop (1994)
10.1101/gad.13.5.517 / Genes Dev. / Defects in Saccharomyces cerevisiae protein phosphatase type I activate the spindle/kinetochore checkpoint by Bloecher (1999)
10.1242/dev.126.10.2227 / Development / The Caenorhabditis elegans gene ncc-1 encodes a cdc2-related kinase required for M phase in meiotic and mitotic cell divisions, but not for S phase by Boxem (1999)
10.1111/j.1432-1033.1973.tb02664.x / Eur. J. Biochem. / Phosphorylation of very-lysine-rich histone in Physarum polycephalum. Correlation with chromosome condensation by Bradbury (1973)
10.1093/genetics/77.1.71 / Genetics / The genetics of Caenorhabditis elegans by Brenner (1974)
10.1093/genetics/135.3.677 / Genetics / Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast by Chan (1993)
10.1016/S1097-2765(00)80068-4 / Mol. Cell / Gametogenesis in yeast is regulated by a transcriptional cascade dependent on Ndt80 by Chu (1998)
10.1126/science.282.5389.699 / Science / The transcriptional program of sporulation in budding yeast by Chu (1998)
10.1016/0014-5793(89)80803-8 / FEBS Lett. / An improved procedure for identifying and quantitating protein phosphatases in mammalian tissues by Cohen (1989)
{'key': '10.1016/S0092-8674(00)00034-9_BIB17', 'series-title': 'The Cell Cycle', 'article-title': 'Preparation of synchronous cultures of the yeasts, Saccharomyces cerevisiae and Schizosaccharomyces pombe', 'author': 'Creanor', 'year': '1993'} / The Cell Cycle / Preparation of synchronous cultures of the yeasts, Saccharomyces cerevisiae and Schizosaccharomyces pombe by Creanor (1993)
10.1093/emboj/19.3.379 / EMBO J. / Core histone N-termini play an essential role in mitotic chromosome condensation by de La Barre (2000)
10.1016/0092-8674(89)90337-1 / Cell / The bimG gene of Aspergillus nidulans, required for completion of anaphase, encodes a homolog of mammalian phosphoprotein phosphatase 1 by Doonan (1989)
10.1083/jcb.106.3.567 / J. Cell Biol. / Meiotic chromosome behavior in spread preparations of yeast by Dresser (1988)
10.1101/gad.10.10.1247 / Genes Dev. / Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4 by Edmondson (1996)
10.1038/35888 / Nature / Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans by Fire (1998)
10.1093/genetics/139.2.579 / Genetics / gld-1, a tumor suppressor gene required for oocyte development in Caenorhabditis elegans by Francis (1995)
10.1128/MCB.14.7.4731 / Mol. Cell. Biol. / Type 1 protein phosphatase acts in opposition to IpL1 protein kinase in regulating yeast chromosome segregation by Francisco (1994)
10.1242/jcs.112.21.3591 / J. Cell Sci. / Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine- threonine kinases by Giet (1999)
10.1016/0092-8674(95)90374-7 / Cell / Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles by Glover (1995)
10.1083/jcb.138.3.643 / J. Cell Biol. / A novel mammalian, mitotic spindle-associated kinase is related to yeast and fly chromosome segregation regulators by Gopalan (1997)
10.1074/jbc.274.36.25543 / J. Biol. Chem. / Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation by Goto (1999)
10.1016/0092-8674(95)90082-9 / Cell / par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed by Guo (1995)
10.1002/j.1460-2075.1995.tb07078.x / EMBO J. / Chromosome condensation induced by fostriecin does not require p34cdc2 kinase activity and histone H1 hyperphosphorylation, but is associated with enhanced histone H2A and H3 phosphorylation by Guo (1995)
10.1083/jcb.60.2.356 / J. Cell Biol. / Cell cycle-specific changes in histone phosphorylation associated with cell proliferation and chromosome condensation by Gurley (1974)
10.1007/s004120050256 / Chromosoma / Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation by Hendzel (1997)
10.1146/annurev.biochem.69.1.115 / Annu. Rev. Biochem. / Chromosome cohesion, condensation, and separation by Hirano (2000)
10.1006/dbio.1996.0293 / Dev. Biol. / GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development by Jones (1996)
10.1242/dev.125.10.1803 / Development / Genetic regulation of entry into meiosis in Caenorhabditis elegans by Kadyk (1998)
10.1083/jcb.145.7.1381 / J. Cell Biol. / Sli15 associates with the ipl1 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae by Kim (1999)
10.1074/jbc.272.21.13766 / J. Biol. Chem. / Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1 by Kimura (1997)
10.1093/genetics/110.2.187 / Genetics / The role of the SPO11 gene in meiotic recombination in yeast by Klapholz (1985)
10.1016/S0092-8674(00)80920-4 / Cell / MIX-1 by Lieb (1998)
10.1016/S0092-8674(00)80917-4 / Cell / POP-1 and anterior-posterior fate decisions in C. elegans embryos by Lin (1998)
10.1016/0014-5793(82)80490-0 / FEBS Lett. / Modification of histones during the mitotic and meiotic cycle of yeast by Marian (1982)
10.1016/S0092-8674(00)81684-0 / Cell / A long twentieth century of the cell cycle and beyond by Nurse (2000)
10.1016/0092-8674(89)90338-3 / Cell / The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases by Ohkura (1989)
10.1126/science.8266099 / Science / Chromosome condensation in Xenopus mitotic extracts without histone H1 by Ohsumi (1993)
10.1242/jcs.111.5.557 / J. Cell Sci. / The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly by Roghi (1998)
10.1126/science.285.5429.886 / Science / Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3 by Sassone-Corsi (1999)
10.1101/gad.13.5.545 / Genes Dev. / Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p by Sassoon (1999)
{'key': '10.1016/S0092-8674(00)00034-9_BIB48', 'series-title': 'Mass Spectrometry in Biology and Medicine', 'article-title': 'Sequencing the primordial soup', 'author': 'Shabanowitz', 'year': '2000'} / Mass Spectrometry in Biology and Medicine / Sequencing the primordial soup by Shabanowitz (2000)
10.1242/dev.125.22.4391 / Development / A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos by Schumacher (1998)
10.1083/jcb.143.6.1635 / J. Cell Biol. / AIR-2 by Schumacher (1998)
10.1016/0092-8674(95)90051-9 / Cell / Linker histones are not essential and affect chromatin condensation in vivo by Shen (1995)
10.1146/annurev.cb.10.110194.000415 / Annu. Rev. Cell Biol. / Protein serine/threonine phosphatases—new avenues for cell regulation by Shenolikar (1994)
10.1016/0076-6879(91)94004-V / Methods Enzymol. / Getting started with yeast by Sherman (1991)
10.1111/j.1432-1033.1990.tb19199.x / Eur. J. Biochem. / Mitosis-specific histone H3 phosphorylation in vitro in nucleosome structures by Shibata (1990)
10.1016/S0091-679X(08)60585-3 / Methods Cell Biol. / Mutations that affect chromosomal proteins in yeast by Smith (1991)
10.1002/(SICI)1097-0061(199612)12:16<1647::AID-YEA71>3.0.CO;2-Q / Yeast / Yeast protein serine/threonine phosphatases by Stark (1996)
10.1101/gad.12.5.599 / Genes Dev. / Histone acetylation and transcriptional regulatory mechanisms by Struhl (1998)
10.1128/MCB.14.2.896 / Mol. Cell. Biol. / The mutant type 1 protein phosphatase encoded by glc7-1 from Saccharomyces cerevisiae fails to interact productively with the GAC1-encoded regulatory subunit by Stuart (1994)
10.1101/SQB.1991.056.01.011 / Cold Spring Harb. Symp. Quant. Biol. / The SIT4 protein phosphatase is required in late G1 for progression into S phase by Sutton (1991)
10.1083/jcb.135.5.1219 / J. Cell Biol. / Phosphorylation of linker histone is associated with transcriptional activation in a normally silent nucleus by Sweet (1996)
10.1016/0092-8674(93)90114-6 / Cell / ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsis by Sym (1993)
10.1126/science.282.5388.430 / Science / RNAi in C. elegans by Tabara (1998)
{'key': '10.1016/S0092-8674(00)00034-9_BIB63', 'first-page': '4811', 'article-title': 'Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells', 'volume': '58', 'author': 'Tatsuka', 'year': '1998', 'journal-title': 'Cancer Res.'} / Cancer Res. / Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells by Tatsuka (1998)
10.1016/S0021-9258(20)65104-3 / J. Biol. Chem. / The in vitro phosphorylation of chromatin by the catalytic subunit of cAMP-dependent protein kinase by Taylor (1982)
10.1093/emboj/17.3.667 / EMBO J. / AIM-1 by Terada (1998)
10.1006/scdb.1999.0302 / Semin. Cell Dev. Biol. / MAP kinase-mediated signalling to nucleosomes and immediate-early gene induction by Thomson (1999)
10.1242/jcs.111.23.3497 / J. Cell Sci. / Histone H3 phosphorylation is required for the initiation, but not maintenance, of mammalian chromosome condensation by Van Hooser (1998)
10.1093/genetics/155.1.69 / Genetics / Genetic interactions between GLC7, PPZ1, and PPZ2 in Saccharomyces cerevisiae by Venturi (2000)
10.1073/pnas.95.13.7480 / Proc. Natl. Acad. Sci. USA / Phosphorylation of histone H3 at serine 10 is correlated with chromosome condensation during mitosis and meiosis in Tetrahymena by Wei (1998)
10.1016/S0092-8674(00)80718-7 / Cell / Phosphorylation of histone H3 is required for proper chromosome condensation and segregation by Wei (1999)
10.1016/S0925-4773(99)00020-9 / Mech. Dev. / Stu-7/air-2 is a C. elegans aurora homologue essential for chromosome segregation during embryonic and post-embryonic development by Woollard (1999)
10.1038/2496 / Nat. Genet. / Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation by Zhou (1998)

Dates

Type	When
Created	21 years, 4 months ago (April 15, 2004, 5:36 a.m.)
Deposited	4 years, 2 months ago (June 15, 2021, 12:33 p.m.)
Indexed	5 days ago (Aug. 27, 2025, 12:31 p.m.)
Issued	25 years, 1 month ago (Aug. 1, 2000)
Published	25 years, 1 month ago (Aug. 1, 2000)
Published Print	25 years, 1 month ago (Aug. 1, 2000)

Funders 0

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BibTeX

@article{Hsu_2000, title={Mitotic Phosphorylation of Histone H3 Is Governed by Ipl1/aurora Kinase and Glc7/PP1 Phosphatase in Budding Yeast and Nematodes}, volume={102}, ISSN={0092-8674}, url={http://dx.doi.org/10.1016/s0092-8674(00)00034-9}, DOI={10.1016/s0092-8674(00)00034-9}, number={3}, journal={Cell}, publisher={Elsevier BV}, author={Hsu, Jer-Yuan and Sun, Zu-Wen and Li, Xiumin and Reuben, Melanie and Tatchell, Kelly and Bishop, Douglas K and Grushcow, Jeremy M and Brame, Cynthia J and Caldwell, Jennifer A and Hunt, Donald F and Lin, Rueyling and Smith, M.Mitchell and Allis, C.David}, year={2000}, month=aug, pages={279–291} }

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      "DOI": "10.1002/j.1460-2075.1986.tb04551.x",
      "article-title": "Nuclease hypersensitive regions with adjacent positioned nucleosomes mark the gene boundaries of the PHO5/PHO3 locus in yeast",
      "volume": "5",
      "author": "Almer",
      "year": "1986",
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      "article-title": "Differential subcellular localization of protein phosphatase-1 alpha, gamma1, and delta isoforms during both interphase and mitosis in mammalian cells",
      "volume": "141",
      "author": "Andreassen",
      "year": "1998",
      "journal-title": "J. Cell Biol."
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    {
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      "article-title": "One of the protein phosphatase 1 isoenzymes in Drosophila is essential for mitosis",
      "volume": "63",
      "author": "Axton",
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      "journal-title": "Cell"
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      "author": "Baker",
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      "volume": "13",
      "author": "Biggins",
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      "journal-title": "Genes Dev."
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      "article-title": "The Aurora/Ipl1p kinase family",
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      "author": "Bischoff",
      "year": "1999",
      "journal-title": "Trends Cell Biol."
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      "DOI": "10.1016/0014-5793(89)80803-8",
      "article-title": "An improved procedure for identifying and quantitating protein phosphatases in mammalian tissues",
      "volume": "250",
      "author": "Cohen",
      "year": "1989",
      "journal-title": "FEBS Lett."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB17",
      "series-title": "The Cell Cycle",
      "article-title": "Preparation of synchronous cultures of the yeasts, Saccharomyces cerevisiae and Schizosaccharomyces pombe",
      "author": "Creanor",
      "year": "1993"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB18",
      "doi-asserted-by": "crossref",
      "first-page": "379",
      "DOI": "10.1093/emboj/19.3.379",
      "article-title": "Core histone N-termini play an essential role in mitotic chromosome condensation",
      "volume": "19",
      "author": "de La Barre",
      "year": "2000",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB19",
      "doi-asserted-by": "crossref",
      "first-page": "987",
      "DOI": "10.1016/0092-8674(89)90337-1",
      "article-title": "The bimG gene of Aspergillus nidulans, required for completion of anaphase, encodes a homolog of mammalian phosphoprotein phosphatase 1",
      "volume": "57",
      "author": "Doonan",
      "year": "1989",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB20",
      "doi-asserted-by": "crossref",
      "first-page": "567",
      "DOI": "10.1083/jcb.106.3.567",
      "article-title": "Meiotic chromosome behavior in spread preparations of yeast",
      "volume": "106",
      "author": "Dresser",
      "year": "1988",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "1247",
      "DOI": "10.1101/gad.10.10.1247",
      "article-title": "Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4",
      "volume": "10",
      "author": "Edmondson",
      "year": "1996",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "806",
      "DOI": "10.1038/35888",
      "article-title": "Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans",
      "volume": "391",
      "author": "Fire",
      "year": "1998",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "579",
      "DOI": "10.1093/genetics/139.2.579",
      "article-title": "gld-1, a tumor suppressor gene required for oocyte development in Caenorhabditis elegans",
      "volume": "139",
      "author": "Francis",
      "year": "1995",
      "journal-title": "Genetics"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "4731",
      "DOI": "10.1128/MCB.14.7.4731",
      "article-title": "Type 1 protein phosphatase acts in opposition to IpL1 protein kinase in regulating yeast chromosome segregation",
      "volume": "14",
      "author": "Francisco",
      "year": "1994",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "3591",
      "DOI": "10.1242/jcs.112.21.3591",
      "article-title": "Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine- threonine kinases",
      "volume": "112",
      "author": "Giet",
      "year": "1999",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "95",
      "DOI": "10.1016/0092-8674(95)90374-7",
      "article-title": "Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles",
      "volume": "81",
      "author": "Glover",
      "year": "1995",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "643",
      "DOI": "10.1083/jcb.138.3.643",
      "article-title": "A novel mammalian, mitotic spindle-associated kinase is related to yeast and fly chromosome segregation regulators",
      "volume": "138",
      "author": "Gopalan",
      "year": "1997",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "25543",
      "DOI": "10.1074/jbc.274.36.25543",
      "article-title": "Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation",
      "volume": "274",
      "author": "Goto",
      "year": "1999",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "611",
      "DOI": "10.1016/0092-8674(95)90082-9",
      "article-title": "par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed",
      "volume": "81",
      "author": "Guo",
      "year": "1995",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "976",
      "DOI": "10.1002/j.1460-2075.1995.tb07078.x",
      "article-title": "Chromosome condensation induced by fostriecin does not require p34cdc2 kinase activity and histone H1 hyperphosphorylation, but is associated with enhanced histone H2A and H3 phosphorylation",
      "volume": "14",
      "author": "Guo",
      "year": "1995",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "356",
      "DOI": "10.1083/jcb.60.2.356",
      "article-title": "Cell cycle-specific changes in histone phosphorylation associated with cell proliferation and chromosome condensation",
      "volume": "60",
      "author": "Gurley",
      "year": "1974",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "348",
      "DOI": "10.1007/s004120050256",
      "article-title": "Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation",
      "volume": "106",
      "author": "Hendzel",
      "year": "1997",
      "journal-title": "Chromosoma"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "115",
      "DOI": "10.1146/annurev.biochem.69.1.115",
      "article-title": "Chromosome cohesion, condensation, and separation",
      "volume": "69",
      "author": "Hirano",
      "year": "2000",
      "journal-title": "Annu. Rev. Biochem."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "165",
      "DOI": "10.1006/dbio.1996.0293",
      "article-title": "GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development",
      "volume": "180",
      "author": "Jones",
      "year": "1996",
      "journal-title": "Dev. Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "1803",
      "DOI": "10.1242/dev.125.10.1803",
      "article-title": "Genetic regulation of entry into meiosis in Caenorhabditis elegans",
      "volume": "125",
      "author": "Kadyk",
      "year": "1998",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "1381",
      "DOI": "10.1083/jcb.145.7.1381",
      "article-title": "Sli15 associates with the ipl1 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae",
      "volume": "145",
      "author": "Kim",
      "year": "1999",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "13766",
      "DOI": "10.1074/jbc.272.21.13766",
      "article-title": "Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1",
      "volume": "272",
      "author": "Kimura",
      "year": "1997",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "187",
      "DOI": "10.1093/genetics/110.2.187",
      "article-title": "The role of the SPO11 gene in meiotic recombination in yeast",
      "volume": "110",
      "author": "Klapholz",
      "year": "1985",
      "journal-title": "Genetics"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB39",
      "doi-asserted-by": "crossref",
      "first-page": "265",
      "DOI": "10.1016/S0092-8674(00)80920-4",
      "article-title": "MIX-1",
      "volume": "92",
      "author": "Lieb",
      "year": "1998",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "229",
      "DOI": "10.1016/S0092-8674(00)80917-4",
      "article-title": "POP-1 and anterior-posterior fate decisions in C. elegans embryos",
      "volume": "92",
      "author": "Lin",
      "year": "1998",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "72",
      "DOI": "10.1016/0014-5793(82)80490-0",
      "article-title": "Modification of histones during the mitotic and meiotic cycle of yeast",
      "volume": "139",
      "author": "Marian",
      "year": "1982",
      "journal-title": "FEBS Lett."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB42",
      "doi-asserted-by": "crossref",
      "first-page": "71",
      "DOI": "10.1016/S0092-8674(00)81684-0",
      "article-title": "A long twentieth century of the cell cycle and beyond",
      "volume": "100",
      "author": "Nurse",
      "year": "2000",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "997",
      "DOI": "10.1016/0092-8674(89)90338-3",
      "article-title": "The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases",
      "volume": "57",
      "author": "Ohkura",
      "year": "1989",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB44",
      "doi-asserted-by": "crossref",
      "first-page": "2033",
      "DOI": "10.1126/science.8266099",
      "article-title": "Chromosome condensation in Xenopus mitotic extracts without histone H1",
      "volume": "262",
      "author": "Ohsumi",
      "year": "1993",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "557",
      "DOI": "10.1242/jcs.111.5.557",
      "article-title": "The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly",
      "volume": "111",
      "author": "Roghi",
      "year": "1998",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "886",
      "DOI": "10.1126/science.285.5429.886",
      "article-title": "Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3",
      "volume": "285",
      "author": "Sassone-Corsi",
      "year": "1999",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB47",
      "doi-asserted-by": "crossref",
      "first-page": "545",
      "DOI": "10.1101/gad.13.5.545",
      "article-title": "Regulation of Saccharomyces cerevisiae kinetochores by the type 1 phosphatase Glc7p",
      "volume": "13",
      "author": "Sassoon",
      "year": "1999",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB48",
      "series-title": "Mass Spectrometry in Biology and Medicine",
      "article-title": "Sequencing the primordial soup",
      "author": "Shabanowitz",
      "year": "2000"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "4391",
      "DOI": "10.1242/dev.125.22.4391",
      "article-title": "A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos",
      "volume": "125",
      "author": "Schumacher",
      "year": "1998",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB50",
      "doi-asserted-by": "crossref",
      "first-page": "1635",
      "DOI": "10.1083/jcb.143.6.1635",
      "article-title": "AIR-2",
      "volume": "143",
      "author": "Schumacher",
      "year": "1998",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB51",
      "doi-asserted-by": "crossref",
      "first-page": "47",
      "DOI": "10.1016/0092-8674(95)90051-9",
      "article-title": "Linker histones are not essential and affect chromatin condensation in vivo",
      "volume": "82",
      "author": "Shen",
      "year": "1995",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB52",
      "doi-asserted-by": "crossref",
      "first-page": "55",
      "DOI": "10.1146/annurev.cb.10.110194.000415",
      "article-title": "Protein serine/threonine phosphatases\u2014new avenues for cell regulation",
      "volume": "10",
      "author": "Shenolikar",
      "year": "1994",
      "journal-title": "Annu. Rev. Cell Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB53",
      "doi-asserted-by": "crossref",
      "first-page": "3",
      "DOI": "10.1016/0076-6879(91)94004-V",
      "article-title": "Getting started with yeast",
      "volume": "194",
      "author": "Sherman",
      "year": "1991",
      "journal-title": "Methods Enzymol."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB54",
      "doi-asserted-by": "crossref",
      "first-page": "87",
      "DOI": "10.1111/j.1432-1033.1990.tb19199.x",
      "article-title": "Mitosis-specific histone H3 phosphorylation in vitro in nucleosome structures",
      "volume": "192",
      "author": "Shibata",
      "year": "1990",
      "journal-title": "Eur. J. Biochem."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB55",
      "doi-asserted-by": "crossref",
      "first-page": "485",
      "DOI": "10.1016/S0091-679X(08)60585-3",
      "article-title": "Mutations that affect chromosomal proteins in yeast",
      "volume": "35",
      "author": "Smith",
      "year": "1991",
      "journal-title": "Methods Cell Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB56",
      "doi-asserted-by": "crossref",
      "first-page": "1647",
      "DOI": "10.1002/(SICI)1097-0061(199612)12:16<1647::AID-YEA71>3.0.CO;2-Q",
      "article-title": "Yeast protein serine/threonine phosphatases",
      "volume": "12",
      "author": "Stark",
      "year": "1996",
      "journal-title": "Yeast"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB57",
      "doi-asserted-by": "crossref",
      "first-page": "599",
      "DOI": "10.1101/gad.12.5.599",
      "article-title": "Histone acetylation and transcriptional regulatory mechanisms",
      "volume": "12",
      "author": "Struhl",
      "year": "1998",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB58",
      "doi-asserted-by": "crossref",
      "first-page": "896",
      "DOI": "10.1128/MCB.14.2.896",
      "article-title": "The mutant type 1 protein phosphatase encoded by glc7-1 from Saccharomyces cerevisiae fails to interact productively with the GAC1-encoded regulatory subunit",
      "volume": "14",
      "author": "Stuart",
      "year": "1994",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB59",
      "doi-asserted-by": "crossref",
      "first-page": "75",
      "DOI": "10.1101/SQB.1991.056.01.011",
      "article-title": "The SIT4 protein phosphatase is required in late G1 for progression into S phase",
      "volume": "56",
      "author": "Sutton",
      "year": "1991",
      "journal-title": "Cold Spring Harb. Symp. Quant. Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB60",
      "doi-asserted-by": "crossref",
      "first-page": "1219",
      "DOI": "10.1083/jcb.135.5.1219",
      "article-title": "Phosphorylation of linker histone is associated with transcriptional activation in a normally silent nucleus",
      "volume": "135",
      "author": "Sweet",
      "year": "1996",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB61",
      "doi-asserted-by": "crossref",
      "first-page": "365",
      "DOI": "10.1016/0092-8674(93)90114-6",
      "article-title": "ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsis",
      "volume": "72",
      "author": "Sym",
      "year": "1993",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB62",
      "doi-asserted-by": "crossref",
      "first-page": "430",
      "DOI": "10.1126/science.282.5388.430",
      "article-title": "RNAi in C. elegans",
      "volume": "282",
      "author": "Tabara",
      "year": "1998",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB63",
      "first-page": "4811",
      "article-title": "Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells",
      "volume": "58",
      "author": "Tatsuka",
      "year": "1998",
      "journal-title": "Cancer Res."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB64",
      "doi-asserted-by": "crossref",
      "first-page": "6056",
      "DOI": "10.1016/S0021-9258(20)65104-3",
      "article-title": "The in vitro phosphorylation of chromatin by the catalytic subunit of cAMP-dependent protein kinase",
      "volume": "257",
      "author": "Taylor",
      "year": "1982",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB65",
      "doi-asserted-by": "crossref",
      "first-page": "667",
      "DOI": "10.1093/emboj/17.3.667",
      "article-title": "AIM-1",
      "volume": "17",
      "author": "Terada",
      "year": "1998",
      "journal-title": "EMBO J."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB66",
      "doi-asserted-by": "crossref",
      "first-page": "205",
      "DOI": "10.1006/scdb.1999.0302",
      "article-title": "MAP kinase-mediated signalling to nucleosomes and immediate-early gene induction",
      "volume": "10",
      "author": "Thomson",
      "year": "1999",
      "journal-title": "Semin. Cell Dev. Biol."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB67",
      "doi-asserted-by": "crossref",
      "first-page": "3497",
      "DOI": "10.1242/jcs.111.23.3497",
      "article-title": "Histone H3 phosphorylation is required for the initiation, but not maintenance, of mammalian chromosome condensation",
      "volume": "111",
      "author": "Van Hooser",
      "year": "1998",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB68",
      "doi-asserted-by": "crossref",
      "first-page": "69",
      "DOI": "10.1093/genetics/155.1.69",
      "article-title": "Genetic interactions between GLC7, PPZ1, and PPZ2 in Saccharomyces cerevisiae",
      "volume": "155",
      "author": "Venturi",
      "year": "2000",
      "journal-title": "Genetics"
    },
    {
      "key": "10.1016/S0092-8674(00)00034-9_BIB69",
      "doi-asserted-by": "crossref",
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