DOI: 10.1016/s0028-3908(99)00064-7. Dopamine D2 receptor knock-out mice are insensitive to the hypolocomotor and hypothermic effects of dopamine D2/D3 receptor agonists

Dopamine D2 receptor knock-out mice are insensitive to the hypolocomotor and hypothermic effects of dopamine D2/D3 receptor agonists

10.1016/s0028-3908(99)00064-7

Crossref journal-article

Elsevier BV

Neuropharmacology (78)

Bibliography

Boulay, D., Depoortere, R., Perrault, G., Borrelli, E., & Sanger, D. J. (1999). Dopamine D2 receptor knock-out mice are insensitive to the hypolocomotor and hypothermic effects of dopamine D2/D3 receptor agonists. Neuropharmacology, 38(9), 1389â1396.

Authors 5

D Boulay (first)
R Depoortere (additional)
Gh Perrault (additional)
E Borrelli (additional)
D.J Sanger (additional)

References 29 Referenced 83

10.1073/pnas.93.5.1945 / Proc. Natl. Acad. Sci. USA / A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice by Accili (1996)
10.1038/377424a0 / Nature / Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors by Baik (1995)
10.1016/S0028-3908(98)00213-5 / Neuropharmacology / Dopamine D3 receptor agonists produce similar decreases in body temperature and locomotor activity in D3 knock-out and wild-type mice by Boulay (1999)
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10.1016/0014-2999(89)90837-6 / Eur. J. Pharmacol. / Biphasic effect of d-2 agonist quinpirole on locomotion and movements by Eilam (1989)
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10.1016/S1359-6446(97)01075-1 / Drug Discov. Today / Compounds selective for dopamine receptor subtypes by Kebabian (1997)
10.1016/S0896-6273(00)80351-7 / Neuron / Pituitary lactotroph hyperplasia and chronic hyperprolactinemia in dopamine D2 receptor-deficient mice by Kelly (1997)
10.1523/JNEUROSCI.18-09-03470.1998 / J. Neurosci. / Locomotor activity in D2 dopamine receptor-deficient mice is determined by gene dosage, genetic background, and developmental adaptations by Kelly (1998)
10.1523/JNEUROSCI.18-06-02231.1998 / J. Neurosci. / Alterations in dopamine release but not dopamine autoreceptor function in dopamine D3 receptor mutant mice by Koeltzow (1998)
10.1016/S0166-2236(96)20022-0 / Trends Neurosci. / Mice, gene targeting and behaviour: More than just genetic background by Lathe (1996)
10.1016/S0006-8993(98)00146-2 / Brain Res. / Lack of autoreceptor-mediated inhibitory control of dopamine release in striatal synaptosomes of D2 receptor-deficient mice by L’hirondel (1998)
10.1038/41567 / Nature / Absence of opiate rewarding effects in mice lacking dopamine D2 receptors by Maldonado (1997)
10.1016/0091-3057(89)90223-2 / Pharmacol. Biochem. Behav. / Hypothermia in mice: D2 dopamine receptor mediation and absence of spare receptors by Meller (1989)
10.1111/j.2042-7158.1979.tb13508.x / J. Pharm. Pharmacol. / Hypothermic effects of apomorphine homologues in mice by Menon (1979)
{'key': '10.1016/S0028-3908(99)00064-7_BIB17', 'first-page': '323', 'article-title': 'Loss of autoreceptor function in dopaminergic neurons from dopamine D2 receptor deficient mice', 'volume': '79', 'author': 'Mercuri', 'year': '1997', 'journal-title': 'Neuroscience'} / Neuroscience / Loss of autoreceptor function in dopaminergic neurons from dopamine D2 receptor deficient mice by Mercuri (1997)
{'key': '10.1016/S0028-3908(99)00064-7_BIB18', 'first-page': '885', 'article-title': 'Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: I. Activation of postsynaptic D3 receptors mediates hypothermia, whereas blockade of D2 receptors elicits prolactin secretion and catalepsy', 'volume': '275', 'author': 'Millan', 'year': '1995', 'journal-title': 'J. Pharmacol. Exp. Ther.'} / J. Pharmacol. Exp. Ther. / Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: I. Activation of postsynaptic D3 receptors mediates hypothermia, whereas blockade of D2 receptors elicits prolactin secretion and catalepsy by Millan (1995)
10.1097/00008877-199605001-00189 / Behav. Pharmacol. / Hypothermia and climbing behaviour induced by D2/D3 dopamine agonists in mice by Perrault (1996)
10.1038/2843 / Nature Neurosci. / Alcohol preference and sensitivity are markedly reduced in mice lacking dopamine D2 receptors by Phillips (1998)
10.1016/S0896-6273(00)80352-9 / Neuron / Antiproliferative role of dopamine: Loss of D2 receptors causes hormonal dysfunction and pituitary hyperplasia by Saiardi (1997)
10.1016/0014-2999(92)90254-2 / Eur. J. Pharmacol. / Effects on body temperature in mice differentiate between dopamine D2 receptor agonists with high and low efficacies by Sanchez (1992)
10.1097/00001756-199501000-00026 / NeuroReport / A functional test identifies dopamine agonists selective for D3 versus D2 receptors by Sautel (1995)
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10.1007/BF01244979 / J. Neural Transm. (Gen. Sect) / The dopamine D3-receptor: a postsynaptic receptor inhibitory on rat locomotor activity by Waters (1993)
10.1016/S0014-2999(98)00312-4 / Eur. J. Pharmacol. / Dopamine D2 and D4 receptor ligands: relation to antipsychotic action by Wilson (1998)
10.1016/S0896-6273(00)80965-4 / Neuron / Dopamine D3 receptor mutant mice exhibit increased behavioral sensitivity to concurrent stimulation of D1 and D2 receptors by Xu (1997)
10.1002/(SICI)1098-2396(19990301)31:3<210::AID-SYN6>3.0.CO;2-0 / Synapse / Dopamine D3 receptor mutant and wild-type mice exhibit identical responses to putative D3 receptor-selective agonists and antagonists by Xu (1999)

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 2:55 p.m.)
Deposited	5 years, 7 months ago (Jan. 28, 2020, 2:46 p.m.)
Indexed	1 month, 1 week ago (July 28, 2025, 5:24 p.m.)
Issued	26 years ago (Sept. 1, 1999)
Published	26 years ago (Sept. 1, 1999)
Published Print	26 years ago (Sept. 1, 1999)

Funders 0

None

BibTeX

@article{Boulay_1999, title={Dopamine D2 receptor knock-out mice are insensitive to the hypolocomotor and hypothermic effects of dopamine D2/D3 receptor agonists}, volume={38}, ISSN={0028-3908}, url={http://dx.doi.org/10.1016/s0028-3908(99)00064-7}, DOI={10.1016/s0028-3908(99)00064-7}, number={9}, journal={Neuropharmacology}, publisher={Elsevier BV}, author={Boulay, D and Depoortere, R and Perrault, Gh and Borrelli, E and Sanger, D.J}, year={1999}, month=sep, pages={1389–1396} }

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    "0028-3908"
  ],
  "subject": [],
  "container-title-short": "Neuropharmacology",
  "published": {
    "date-parts": [
      [
        1999,
        9
      ]
    ]
  }
}