DOI: 10.1016/s0021-9258(19)74018-6. Identification of residues in the first cytoplasmic loop of P-glycoprotein involved in the function of chimeric human MDR1-MDR2 transporters.

Identification of residues in the first cytoplasmic loop of P-glycoprotein involved in the function of chimeric human MDR1-MDR2 transporters.

10.1016/s0021-9258(19)74018-6

Crossref journal-article

Elsevier BV

Journal of Biological Chemistry (78)

Bibliography

Currier, S. J., Kane, S. E., Willingham, M. C., Cardarelli, C. O., Pastan, I., & Gottesman, M. M. (1992). Identification of residues in the first cytoplasmic loop of P-glycoprotein involved in the function of chimeric human MDR1-MDR2 transporters. Journal of Biological Chemistry, 267(35), 25153â25159.

Authors 6

S.J. Currier (first)
S.E. Kane (additional)
M.C. Willingham (additional)
C.O. Cardarelli (additional)
I Pastan (additional)
M.M. Gottesman (additional)

References 36 Referenced 95

10.1007/BF01534700 / Somat. Cell Mol. Genet. by Akiyama (1985)
10.1007/BF01026439 / J. Protein Chem. by Brandt-Rauf (1989)
10.1016/S0021-9258(19)84855-X / J. Biol. Chem. by Bruggemann (1989)
{'key': '10.1016/S0021-9258(19)74018-6_bib4', 'first-page': '595', 'volume': '11', 'author': 'Buschman', 'year': '1991', 'journal-title': 'Mol. Cell. Biol'} / Mol. Cell. Biol by Buschman (1991)
10.1016/0092-8674(86)90595-7 / Cell by Chen (1986)
10.1016/0092-8674(88)90568-5 / Cell by Choi (1988)
10.1016/S0021-9258(18)71688-8 / J. Biol. Chem. by Currier (1989)
{'key': '10.1016/S0021-9258(19)74018-6_bib8', 'first-page': '1652', 'volume': '10', 'author': 'Devault', 'year': '1990', 'journal-title': 'Mol. Cell. Biol.'} / Mol. Cell. Biol. by Devault (1990)
10.1016/S0021-9258(20)64357-5 / J. Biol. Chem. by Devine (1991)
10.1021/bi00461a013 / Biochemistry by Germann (1990)
10.1016/S0021-9258(18)37730-5 / J. Biol. Chem. by Gottesman (1988)
10.1038/323728a0 / Nature by Gros (1986)
10.1016/0092-8674(86)90594-5 / Cell by Gros (1986)
{'key': '10.1016/S0021-9258(19)74018-6_bib14', 'first-page': '2770', 'volume': '8', 'author': 'Gros', 'year': '1988', 'journal-title': 'Mol. Cell. Biol.'} / Mol. Cell. Biol. by Gros (1988)
10.1073/pnas.88.16.7289 / Proc. Natl. Acad. Sci. U. S. A. by Gros (1991)
10.1073/pnas.83.20.7785 / Proc. Natl. Acad. Sci. U. S. A. by Hamada (1986)
10.1016/S0021-9258(18)63784-6 / J. Biol. Chem. by Horio (1989)
{'key': '10.1016/S0021-9258(19)74018-6_bib18', 'first-page': '178', 'volume': '8', 'author': 'Jones', 'year': '1990', 'journal-title': 'Biotechniques'} / Biotechniques by Jones (1990)
10.1016/0378-1119(89)90518-0 / Gene (Amst.) by Kane (1989)
10.1007/BF00762963 / J. Bioenerg. Biomembr. by Kane (1990)
10.1073/pnas.83.10.3136 / Proc. Natl. Acad. Sci. U. S. A. by Kaufman (1986)
10.1016/0006-291X(89)91985-2 / Biochem. Biophys. Res. Commun. by Kioka (1989)
10.1073/pnas.82.2.488 / Proc. Natl. Acad. Sci. U. S. A. by Kunkel (1985)
{'key': '10.1016/S0021-9258(19)74018-6_bib24', 'first-page': '506', 'volume': '65', 'author': 'Maxam', 'year': '1980', 'journal-title': 'Methods Enzymol.'} / Methods Enzymol. by Maxam (1980)
10.1073/pnas.85.12.4486 / Proc. Natl. Acad. Sci. U. S. A. by Pastan (1988)
10.1073/pnas.87.18.7225 / Proc. Natl. Acad. Sci. U. S. A. by Safa (1990)
{'key': '10.1016/S0021-9258(19)74018-6_bib27', 'first-page': '213', 'volume': '2', 'author': 'Schinkel', 'year': '1991', 'journal-title': 'Semin. Cancer Biol.'} / Semin. Cancer Biol. by Schinkel (1991)
10.1016/S0021-9258(19)57466-X / J. Biol. Chem. by Shen (1986)
{'key': '10.1016/S0021-9258(19)74018-6_bib29', 'first-page': '4039', 'volume': '6', 'author': 'Shen', 'year': '1986', 'journal-title': 'Mol. Cell. Biol.'} / Mol. Cell. Biol. by Shen (1986)
10.1016/0378-1119(91)90203-N / Gene (Arnst) by Silverman (1991)
{'key': '10.1016/S0021-9258(19)74018-6_bib31', 'first-page': '327', 'volume': '1', 'author': 'Southern', 'year': '1982', 'journal-title': 'J. Mol. Appl. Genet.'} / J. Mol. Appl. Genet. by Southern (1982)
10.1016/0006-291X(90)91928-L / Biochem. Biophys. Res. Commun by Tanaka (1990)
10.1073/pnas.84.9.3004 / Proc. Natl. Sci. U. S. A. by Ueda (1987)
10.1016/S0021-9258(19)75806-2 / J. Biol. Chem. by Ueda (1987)
10.4049/jimmunol.126.4.1393 / J. Immunol. by Uchiyama (1981)
10.1016/0378-1119(88)90057-1 / Gene (Amst.) by van der Bliek (1988)

Dates

Type	When
Created	4 years, 8 months ago (Jan. 6, 2021, 4:06 p.m.)
Deposited	1 year, 10 months ago (Oct. 16, 2023, 10:56 p.m.)
Indexed	1 week ago (Aug. 30, 2025, 1:14 p.m.)
Issued	32 years, 9 months ago (Dec. 1, 1992)
Published	32 years, 9 months ago (Dec. 1, 1992)
Published Print	32 years, 9 months ago (Dec. 1, 1992)

Funders 0

None

BibTeX

@article{Currier_1992, title={Identification of residues in the first cytoplasmic loop of P-glycoprotein involved in the function of chimeric human MDR1-MDR2 transporters.}, volume={267}, ISSN={0021-9258}, url={http://dx.doi.org/10.1016/s0021-9258(19)74018-6}, DOI={10.1016/s0021-9258(19)74018-6}, number={35}, journal={Journal of Biological Chemistry}, publisher={Elsevier BV}, author={Currier, S.J. and Kane, S.E. and Willingham, M.C. and Cardarelli, C.O. and Pastan, I and Gottesman, M.M.}, year={1992}, month=dec, pages={25153–25159} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        30
      ]
    ],
    "date-time": "2025-08-30T17:14:50Z",
    "timestamp": 1756574090377
  },
  "reference-count": 36,
  "publisher": "Elsevier BV",
  "issue": "35",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            1992,
            12,
            1
          ]
        ],
        "date-time": "1992-12-01T00:00:00Z",
        "timestamp": 723168000000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.elsevier.com/tdm/userlicense/1.0/"
    },
    {
      "start": {
        "date-parts": [
          [
            2020,
            10,
            9
          ]
        ],
        "date-time": "2020-10-09T00:00:00Z",
        "timestamp": 1602201600000
      },
      "content-version": "vor",
      "delay-in-days": 10174,
      "URL": "http://creativecommons.org/licenses/by/4.0/"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1992,
        12
      ]
    ]
  },
  "DOI": "10.1016/s0021-9258(19)74018-6",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2021,
        1,
        6
      ]
    ],
    "date-time": "2021-01-06T21:06:09Z",
    "timestamp": 1609967169000
  },
  "page": "25153-25159",
  "source": "Crossref",
  "is-referenced-by-count": 95,
  "title": "Identification of residues in the first cytoplasmic loop of P-glycoprotein involved in the function of chimeric human MDR1-MDR2 transporters.",
  "prefix": "10.1016",
  "volume": "267",
  "author": [
    {
      "given": "S.J.",
      "family": "Currier",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "S.E.",
      "family": "Kane",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "M.C.",
      "family": "Willingham",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "C.O.",
      "family": "Cardarelli",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "I",
      "family": "Pastan",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "M.M.",
      "family": "Gottesman",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "78",
  "reference": [
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib1",
      "doi-asserted-by": "crossref",
      "first-page": "117",
      "DOI": "10.1007/BF01534700",
      "volume": "11",
      "author": "Akiyama",
      "year": "1985",
      "journal-title": "Somat. Cell Mol. Genet."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib2",
      "doi-asserted-by": "crossref",
      "first-page": "563",
      "DOI": "10.1007/BF01026439",
      "volume": "8",
      "author": "Brandt-Rauf",
      "year": "1989",
      "journal-title": "J. Protein Chem."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib3",
      "doi-asserted-by": "crossref",
      "first-page": "15483",
      "DOI": "10.1016/S0021-9258(19)84855-X",
      "volume": "264",
      "author": "Bruggemann",
      "year": "1989",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib4",
      "first-page": "595",
      "volume": "11",
      "author": "Buschman",
      "year": "1991",
      "journal-title": "Mol. Cell. Biol"
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib5",
      "doi-asserted-by": "crossref",
      "first-page": "381",
      "DOI": "10.1016/0092-8674(86)90595-7",
      "volume": "47",
      "author": "Chen",
      "year": "1986",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib6",
      "doi-asserted-by": "crossref",
      "first-page": "519",
      "DOI": "10.1016/0092-8674(88)90568-5",
      "volume": "53",
      "author": "Choi",
      "year": "1988",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib7",
      "doi-asserted-by": "crossref",
      "first-page": "14376",
      "DOI": "10.1016/S0021-9258(18)71688-8",
      "volume": "264",
      "author": "Currier",
      "year": "1989",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib8",
      "first-page": "1652",
      "volume": "10",
      "author": "Devault",
      "year": "1990",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib9",
      "doi-asserted-by": "crossref",
      "first-page": "4545",
      "DOI": "10.1016/S0021-9258(20)64357-5",
      "volume": "266",
      "author": "Devine",
      "year": "1991",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib10",
      "doi-asserted-by": "crossref",
      "first-page": "2295",
      "DOI": "10.1021/bi00461a013",
      "volume": "29",
      "author": "Germann",
      "year": "1990",
      "journal-title": "Biochemistry"
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib11",
      "doi-asserted-by": "crossref",
      "first-page": "12163",
      "DOI": "10.1016/S0021-9258(18)37730-5",
      "volume": "263",
      "author": "Gottesman",
      "year": "1988",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib12",
      "doi-asserted-by": "crossref",
      "first-page": "728",
      "DOI": "10.1038/323728a0",
      "volume": "323",
      "author": "Gros",
      "year": "1986",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib13",
      "doi-asserted-by": "crossref",
      "first-page": "371",
      "DOI": "10.1016/0092-8674(86)90594-5",
      "volume": "47",
      "author": "Gros",
      "year": "1986",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib14",
      "first-page": "2770",
      "volume": "8",
      "author": "Gros",
      "year": "1988",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib15",
      "doi-asserted-by": "crossref",
      "first-page": "7289",
      "DOI": "10.1073/pnas.88.16.7289",
      "volume": "88",
      "author": "Gros",
      "year": "1991",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib16",
      "doi-asserted-by": "crossref",
      "first-page": "7785",
      "DOI": "10.1073/pnas.83.20.7785",
      "volume": "83",
      "author": "Hamada",
      "year": "1986",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib17",
      "doi-asserted-by": "crossref",
      "first-page": "14880",
      "DOI": "10.1016/S0021-9258(18)63784-6",
      "volume": "264",
      "author": "Horio",
      "year": "1989",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib18",
      "first-page": "178",
      "volume": "8",
      "author": "Jones",
      "year": "1990",
      "journal-title": "Biotechniques"
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib19",
      "doi-asserted-by": "crossref",
      "first-page": "439",
      "DOI": "10.1016/0378-1119(89)90518-0",
      "volume": "84",
      "author": "Kane",
      "year": "1989",
      "journal-title": "Gene (Amst.)"
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib20",
      "doi-asserted-by": "crossref",
      "first-page": "593",
      "DOI": "10.1007/BF00762963",
      "volume": "22",
      "author": "Kane",
      "year": "1990",
      "journal-title": "J. Bioenerg. Biomembr."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib21",
      "doi-asserted-by": "crossref",
      "first-page": "3136",
      "DOI": "10.1073/pnas.83.10.3136",
      "volume": "83",
      "author": "Kaufman",
      "year": "1986",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib22",
      "doi-asserted-by": "crossref",
      "first-page": "224",
      "DOI": "10.1016/0006-291X(89)91985-2",
      "volume": "162",
      "author": "Kioka",
      "year": "1989",
      "journal-title": "Biochem. Biophys. Res. Commun."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib23",
      "doi-asserted-by": "crossref",
      "first-page": "488",
      "DOI": "10.1073/pnas.82.2.488",
      "volume": "82",
      "author": "Kunkel",
      "year": "1985",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib24",
      "first-page": "506",
      "volume": "65",
      "author": "Maxam",
      "year": "1980",
      "journal-title": "Methods Enzymol."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib25",
      "doi-asserted-by": "crossref",
      "first-page": "4486",
      "DOI": "10.1073/pnas.85.12.4486",
      "volume": "85",
      "author": "Pastan",
      "year": "1988",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib26",
      "doi-asserted-by": "crossref",
      "first-page": "7225",
      "DOI": "10.1073/pnas.87.18.7225",
      "volume": "87",
      "author": "Safa",
      "year": "1990",
      "journal-title": "Proc. Natl. Acad. Sci. U. S. A."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib27",
      "first-page": "213",
      "volume": "2",
      "author": "Schinkel",
      "year": "1991",
      "journal-title": "Semin. Cancer Biol."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib28",
      "doi-asserted-by": "crossref",
      "first-page": "7762",
      "DOI": "10.1016/S0021-9258(19)57466-X",
      "volume": "261",
      "author": "Shen",
      "year": "1986",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib29",
      "first-page": "4039",
      "volume": "6",
      "author": "Shen",
      "year": "1986",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib30",
      "doi-asserted-by": "crossref",
      "first-page": "229",
      "DOI": "10.1016/0378-1119(91)90203-N",
      "volume": "106",
      "author": "Silverman",
      "year": "1991",
      "journal-title": "Gene (Arnst)"
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib31",
      "first-page": "327",
      "volume": "1",
      "author": "Southern",
      "year": "1982",
      "journal-title": "J. Mol. Appl. Genet."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib32",
      "doi-asserted-by": "crossref",
      "first-page": "180",
      "DOI": "10.1016/0006-291X(90)91928-L",
      "volume": "166",
      "author": "Tanaka",
      "year": "1990",
      "journal-title": "Biochem. Biophys. Res. Commun"
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib33",
      "doi-asserted-by": "crossref",
      "first-page": "3004",
      "DOI": "10.1073/pnas.84.9.3004",
      "volume": "84",
      "author": "Ueda",
      "year": "1987",
      "journal-title": "Proc. Natl. Sci. U. S. A."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib34",
      "doi-asserted-by": "crossref",
      "first-page": "505",
      "DOI": "10.1016/S0021-9258(19)75806-2",
      "volume": "262",
      "author": "Ueda",
      "year": "1987",
      "journal-title": "J. Biol. Chem."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib35",
      "doi-asserted-by": "crossref",
      "first-page": "1393",
      "DOI": "10.4049/jimmunol.126.4.1393",
      "volume": "126",
      "author": "Uchiyama",
      "year": "1981",
      "journal-title": "J. Immunol."
    },
    {
      "key": "10.1016/S0021-9258(19)74018-6_bib36",
      "doi-asserted-by": "crossref",
      "first-page": "401",
      "DOI": "10.1016/0378-1119(88)90057-1",
      "volume": "71",
      "author": "van der Bliek",
      "year": "1988",
      "journal-title": "Gene (Amst.)"
    }
  ],
  "container-title": "Journal of Biological Chemistry",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0021925819740186?httpAccept=text/xml",
      "content-type": "text/xml",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://api.elsevier.com/content/article/PII:S0021925819740186?httpAccept=text/plain",
      "content-type": "text/plain",
      "content-version": "vor",
      "intended-application": "text-mining"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        10,
        17
      ]
    ],
    "date-time": "2023-10-17T02:56:56Z",
    "timestamp": 1697511416000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://linkinghub.elsevier.com/retrieve/pii/S0021925819740186"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1992,
        12
      ]
    ]
  },
  "references-count": 36,
  "journal-issue": {
    "issue": "35",
    "published-print": {
      "date-parts": [
        [
          1992,
          12
        ]
      ]
    }
  },
  "alternative-id": [
    "S0021925819740186"
  ],
  "URL": "http://dx.doi.org/10.1016/S0021-9258(19)74018-6",
  "relation": {},
  "ISSN": [
    "0021-9258"
  ],
  "subject": [],
  "container-title-short": "Journal of Biological Chemistry",
  "published": {
    "date-parts": [
      [
        1992,
        12
      ]
    ]
  }
}