DOI: 10.1016/s0014-5793(97)01108-3. Telethonin, a novel sarcomeric protein of heart and skeletal muscle

Telethonin, a novel sarcomeric protein of heart and skeletal muscle

10.1016/s0014-5793(97)01108-3

Crossref journal-article

Wiley

FEBS Letters (311)

Abstract

In this paper we describe a novel 19 kDa sarcomeric protein named telethonin. The cDNA sequence discloses an open reading frame of 167 amino acids that does not resemble any known protein. Antibodies against a recombinant telethonin fragment were used for Western blot analysis, confirming the presence of this 19 kDa protein in heart and skeletal muscle and revealing an immunofluorescence pattern typical of sarcomeric proteins, overlapping myosin. The frequency of specific cDNA clones in different libraries indicates that the telethonin transcript is amongst the most abundant in skeletal muscle. In human, telethonin maps at 17q12, adjacent to the phenylethanolamine N‐methyltransferase gene.

Bibliography

Valle, G., Faulkner, G., De Antoni, A., Pacchioni, B., Pallavicini, A., Pandolfo, D., Tiso, N., Toppo, S., Trevisan, S., & Lanfranchi, G. (1997). Telethonin, a novel sarcomeric protein of heart and skeletal muscle. FEBS Letters, 415(2), 163â168. Portico.

Authors 10

G Valle (first)
G Faulkner (additional)
A De Antoni (additional)
B Pacchioni (additional)
A Pallavicini (additional)
D Pandolfo (additional)
N Tiso (additional)
S Toppo (additional)
S Trevisan (additional)
G Lanfranchi (additional)

References 27 Referenced 158

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Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 11:16 a.m.)
Deposited	1 year, 11 months ago (Sept. 15, 2023, 4:15 p.m.)
Indexed	2 weeks, 1 day ago (Aug. 20, 2025, 9:01 a.m.)
Issued	27 years, 11 months ago (Sept. 29, 1997)
Published	27 years, 11 months ago (Sept. 29, 1997)
Published Online	26 years, 6 months ago (Feb. 16, 1999)
Published Print	27 years, 11 months ago (Sept. 29, 1997)

Funders 0

None

BibTeX

@article{Valle_1997, title={Telethonin, a novel sarcomeric protein of heart and skeletal muscle}, volume={415}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/s0014-5793(97)01108-3}, DOI={10.1016/s0014-5793(97)01108-3}, number={2}, journal={FEBS Letters}, publisher={Wiley}, author={Valle, G and Faulkner, G and De Antoni, A and Pacchioni, B and Pallavicini, A and Pandolfo, D and Tiso, N and Toppo, S and Trevisan, S and Lanfranchi, G}, year={1997}, month=sep, pages={163–168} }

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