DOI: 10.1016/s0014-5793(03)00393-4. The role of electrostatics in proton‐conducting membrane protein complexes

The role of electrostatics in proton‐conducting membrane protein complexes

10.1016/s0014-5793(03)00393-4

Crossref journal-article

Wiley

FEBS Letters (311)

Abstract

Electrostatic interactions play a key role in the coupling of electron and proton transfer in membrane protein complexes during the conversion of the energy stored in sunlight or reduced substrates into biochemical energy via a transmembrane electrochemical proton potential. Principles of charge stabilization within membrane proteins are reviewed and discussed for photosynthetic reaction centers, cytochrome c oxidases, and diheme‐containing quinol:fumarate reductases. The impact of X‐ray structure‐based electrostatic calculations on the functional interpretation of these structural coordinates, on providing new explanations for experimental observations, and for the design of more focused additional experiments is illustrated by a number of key examples.

Bibliography

Lancaster, C. R. D. (2003). The role of electrostatics in protonâconducting membrane protein complexes. FEBS Letters, 545(1), 52â60. Portico.

Authors 1

C.Roy D. Lancaster (first)

References 55 Referenced 27

10.1126/science.7761829
10.1017/S0033583500005746
10.1016/S0959-440X(98)80041-9
10.1002/prot.340150304
10.1073/pnas.88.20.9151
10.1126/science.388618
10.1007/s007750050116
10.1002/jcc.540090407
10.1002/jcc.540120405
Gunner M.R. and Honig B. (1992) in: The Photosynthetic Bacterial Reaction Center II (Breton J. and Vermeglio A. Eds.) pp. 403–410 Plenum Press New York. (10.1007/978-1-4615-3050-3_44)
10.1016/S0005-2728(00)00060-8
10.1007/BF01881023
10.1073/pnas.88.13.5804
10.1016/S0006-3495(96)79820-X
Lancaster C.R.D. and Michel H. (2001) in: Handbook of Metalloproteins Vol. 1 (Messerschmidt A. Huber R. Poulos T. and Wieghardt K. Eds.) pp. 119–135 Wiley Chichester.
10.1016/S0005-2728(98)00054-1
10.1042/bst0270591
10.1016/S0006-3495(95)80406-6
10.1021/bi982700a
10.1021/bi971921y
10.1016/S0969-2126(97)00285-2
10.1016/S0969-2126(94)00094-8
10.1126/science.276.5313.812
10.1038/46972
10.1016/S0005-2728(01)00174-8
10.1021/bi000557r
Kannt A. and Michel H. (2001) in: Handbook of Metalloproteins Vol. 1 (Messerschmidt A. Huber R. Poulos T. and Wieghardt K. Eds.) pp. 331–347 Wiley Chichester.
Mills D. and Ferguson-Miller S. (2003) FEBS Lett. this issue.
10.1016/S0006-3495(98)73996-7
10.1073/pnas.94.19.10128
10.1073/pnas.95.22.12819
{'key': 'e_1_2_7_33_1', 'first-page': '165', 'volume': '25', 'author': 'Rich P.R.', 'year': '1998', 'journal-title': 'J. Bioenerg. Biomembr.'} / J. Bioenerg. Biomembr. by Rich P.R. (1998)
10.1021/bi9725576
10.1021/bi971091o
10.1021/bi9731697
10.1074/jbc.274.53.37974
10.1016/S0005-2728(99)00097-3
10.1021/bi00013a035
10.1007/BF00762854
10.1021/bi00091a048
10.1038/376660a0
10.1021/bi991764y
10.1021/bi026093
Lancaster C.R.D. (2001) in: Handbook of Metalloproteins Vol. 1 (Messerschmidt A. Huber R. Poulos T. and Wieghardt K. Eds.) pp. 379–401 Wiley Chichester.
10.1016/S0005-2728(01)00240-7
Cecchini G. Maklashina E. Yankovskaya V. Iverson T.M. and Iwata S. (2003) FEBS Lett. this issue.
10.1016/0014-5793(96)00529-7
10.1038/46483
10.1073/pnas.220425797
10.1016/S0005-2736(02)00571-0
Wraight C.A. (1982) in: Function of Quinones in Energy Conserving Systems (Trumpower B.L. Ed.) pp. 181–197 Academic Press New York. (10.1016/B978-0-12-701280-3.50018-9)
10.1021/bi00171a018
10.1074/jbc.M008225200
10.1002/prot.340110407
10.1073/pnas.94.20.10547

Dates

Type	When
Created	22 years, 3 months ago (April 30, 2003, 6:24 p.m.)
Deposited	1 year, 11 months ago (Sept. 16, 2023, 3:53 a.m.)
Indexed	1 year, 5 months ago (March 4, 2024, 3:21 p.m.)
Issued	22 years, 4 months ago (April 18, 2003)
Published	22 years, 4 months ago (April 18, 2003)
Published Online	22 years, 4 months ago (April 18, 2003)
Published Print	22 years, 2 months ago (June 12, 2003)

Funders 0

None

BibTeX

@article{Lancaster_2003, title={The role of electrostatics in proton‐conducting membrane protein complexes}, volume={545}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/s0014-5793(03)00393-4}, DOI={10.1016/s0014-5793(03)00393-4}, number={1}, journal={FEBS Letters}, publisher={Wiley}, author={Lancaster, C.Roy D.}, year={2003}, month=apr, pages={52–60} }

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