Abstract
The forkhead‐associated (FHA) domain is a small protein module recently shown to recognize phosphothreonine epitopes on proteins. It is present in a diverse range of proteins in eukaryotic cells, such as kinases, phosphatases, kinesins, transcription factors, RNA‐binding proteins, and metabolic enzymes. It is also found in a number of bacterial proteins. This suggests that FHA domain‐mediated phospho‐dependent assembly of protein complexes is an ancient and widespread regulatory mechanism.
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Dates
Type | When |
---|---|
Created | 22 years, 10 months ago (Oct. 14, 2002, 11:56 a.m.) |
Deposited | 1 year, 11 months ago (Sept. 17, 2023, 1:06 a.m.) |
Indexed | 1 month, 3 weeks ago (July 2, 2025, 2:30 p.m.) |
Issued | 23 years, 8 months ago (Dec. 20, 2001) |
Published | 23 years, 8 months ago (Dec. 20, 2001) |
Published Online | 23 years, 8 months ago (Dec. 20, 2001) |
Published Print | 23 years, 6 months ago (Feb. 20, 2002) |
@article{Durocher_2001, title={The FHA domain}, volume={513}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/s0014-5793(01)03294-x}, DOI={10.1016/s0014-5793(01)03294-x}, number={1}, journal={FEBS Letters}, publisher={Wiley}, author={Durocher, Daniel and Jackson, Stephen P.}, year={2001}, month=dec, pages={58–66} }