DOI: 10.1016/s0014-5793(01)02486-3. Protein misfolding and disease; protein refolding and therapy

Protein misfolding and disease; protein refolding and therapy

10.1016/s0014-5793(01)02486-3

Crossref journal-article

Wiley

FEBS Letters (311)

Abstract

Diverse human disorders, including several neurodegenerative diseases and systemic amyloidosis, are thought to arise from the misfolding and aggregation of an underlying protein. Recent findings strongly support this hypothesis and have increased our understanding of the molecular mechanism of protein conformational disorders. Many questions are still pending, but the data overall suggest that correction of protein misfolding constitutes a viable therapeutic strategy for conformational diseases.

Bibliography

Soto, C. (2001). Protein misfolding and disease; protein refolding and therapy. FEBS Letters, 498(2â3), 204â207. Portico.

Authors 1

Claudio Soto (first)

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Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 9:54 p.m.)
Deposited	1 year, 11 months ago (Sept. 11, 2023, 7:39 p.m.)
Indexed	1 month, 2 weeks ago (July 12, 2025, 6:44 p.m.)
Issued	24 years, 2 months ago (June 8, 2001)
Published	24 years, 2 months ago (June 8, 2001)
Published Online	24 years, 2 months ago (June 12, 2001)
Published Print	24 years, 2 months ago (June 8, 2001)

Funders 0

None

BibTeX

@article{Soto_2001, title={Protein misfolding and disease; protein refolding and therapy}, volume={498}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/s0014-5793(01)02486-3}, DOI={10.1016/s0014-5793(01)02486-3}, number={2–3}, journal={FEBS Letters}, publisher={Wiley}, author={Soto, Claudio}, year={2001}, month=jun, pages={204–207} }

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