DOI: 10.1016/s0014-5793(00)01760-9. STAM2, a new member of the STAM family, binding to the Janus kinases

STAM2, a new member of the STAM family, binding to the Janus kinases

10.1016/s0014-5793(00)01760-9

Crossref journal-article

Wiley

FEBS Letters (311)

Abstract

We here cloned a cDNA encoding STAM2, a new member of the STAM family, which contains an SH3 domain and ITAM. STAM2 like STAM1 is associated with Jak2 and Jak3, and involved in the signaling for DNA synthesis and c‐myc induction mediated by IL‐2 and GM‐CSF. Co‐expression of the SH3 deletion mutants of STAM1 and STAM2 induces an additive effect on suppressing DNA synthesis upon stimulation with IL‐2 and GM‐CSF, suggesting that STAM1 and STAM2 exhibit compensatory effects on the signaling pathways downstream of Jak2 and Jak3 upon stimulation with GM‐SCF and IL‐2, respectively.

Bibliography

Endo, K., Takeshita, T., Kasai, H., Sasaki, Y., Tanaka, N., Asao, H., Kikuchi, K., Yamada, M., Chen, M., OâShea, J. J., & Sugamura, K. (2000). STAM2, a new member of the STAM family, binding to the Janus kinases. FEBS Letters, 477(1â2), 55â61. Portico.

Authors 11

Kazuhiro Endo (first)
Toshikazu Takeshita (additional)
Hirotake Kasai (additional)
Yoshiteru Sasaki (additional)
Nobuyuki Tanaka (additional)
Hironobu Asao (additional)
Kazu Kikuchi (additional)
Mitsuhiro Yamada (additional)
Min Chen (additional)
John J. O'Shea (additional)
Kazuo Sugamura (additional)

References 24 Referenced 56

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10.1146/annurev.iy.10.040192.001455
10.1073/pnas.92.19.8724
10.1128/MCB.14.7.4335
10.1016/S0092-8674(00)81277-5
10.1002/j.1460-2075.1996.tb00600.x
10.1016/S1074-7613(00)80025-4
10.1093/emboj/17.22.6551
10.1016/S0065-2776(08)60386-7
10.1073/pnas.94.8.3627
10.1006/bbrc.1996.1290
10.1016/S1074-7613(00)80288-5
10.4049/jimmunol.148.7.2154
10.1016/0092-8674(93)90232-F
10.1016/0378-1119(91)90434-D
10.1038/366129a0
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10.1046/j.1365-2443.2000.00303.x
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{'key': 'e_1_2_6_23_1', 'first-page': '1347', 'volume': '7', 'author': 'Harpur A.G.', 'year': '1992', 'journal-title': 'Oncogene'} / Oncogene by Harpur A.G. (1992)
{'key': 'e_1_2_6_24_1', 'first-page': '2415', 'volume': '9', 'author': 'Rane S.G.', 'year': '1994', 'journal-title': 'Oncogene'} / Oncogene by Rane S.G. (1994)
10.1074/jbc.274.27.19129

Dates

Type	When
Created	23 years, 1 month ago (July 25, 2002, 4:40 p.m.)
Deposited	1 year, 11 months ago (Sept. 16, 2023, 1:48 p.m.)
Indexed	4 weeks, 2 days ago (Aug. 6, 2025, 9:13 a.m.)
Issued	25 years, 1 month ago (July 14, 2000)
Published	25 years, 1 month ago (July 14, 2000)
Published Online	25 years, 1 month ago (July 27, 2000)
Published Print	25 years, 1 month ago (July 14, 2000)

Funders 0

None

BibTeX

@article{Endo_2000, title={STAM2, a new member of the STAM family, binding to the Janus kinases}, volume={477}, ISSN={1873-3468}, url={http://dx.doi.org/10.1016/s0014-5793(00)01760-9}, DOI={10.1016/s0014-5793(00)01760-9}, number={1–2}, journal={FEBS Letters}, publisher={Wiley}, author={Endo, Kazuhiro and Takeshita, Toshikazu and Kasai, Hirotake and Sasaki, Yoshiteru and Tanaka, Nobuyuki and Asao, Hironobu and Kikuchi, Kazu and Yamada, Mitsuhiro and Chen, Min and O’Shea, John J. and Sugamura, Kazuo}, year={2000}, month=jul, pages={55–61} }

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