DOI: 10.1016/s0012-1606(03)00206-9. Distinct functions of Rho and Rac are required for convergent extension during Xenopus gastrulation

Distinct functions of Rho and Rac are required for convergent extension during Xenopus gastrulation

10.1016/s0012-1606(03)00206-9

Crossref journal-article

Elsevier BV

Developmental Biology (78)

Bibliography

Tahinci, E., & Symes, K. (2003). Distinct functions of Rho and Rac are required for convergent extension during Xenopus gastrulation. Developmental Biology, 259(2), 318â335.

Authors 2

Emilios Tahinci (first)
Karen Symes (additional)

References 73 Referenced 143

10.1113/jphysiol.2001.013117 / J. Physiol. / Rho and rho kinase modulation of barrier properties by Adamson (2002)
10.1242/dev.121.9.3099 / Development / PDGF signalling is required for gastrulation of Xenopus laevis by Ataliotis (1995)
10.1016/S0092-8674(00)80482-1 / Cell / The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation by Barrett (1997)
10.1126/science.1677215 / Science / Organizer-specific homeobox genes in Xenopus laevis embryos by Blumberg (1991)
10.1083/jcb.137.6.1421 / J. Cell Biol. / The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts by Braga (1997)
10.1016/0092-8674(91)90288-A / Cell / Molecular nature of Spemann’s organizer by Cho (1991)
10.1006/dbio.2002.0602 / Dev. Biol. / Xenopus Cdc42 regulates convergent extension movements during gastrulation through Wnt/Ca(2+) signaling pathway by Choi (2002)
10.1006/dbio.1998.9061 / Dev. Biol. / Cellularization in Drosophila melanogaster is disrupted by the inhibition of rho activity and the activation of Cdc42 function by Crawford (1998)
{'key': '10.1016/S0012-1606(03)00206-9_BIB9', 'series-title': 'Analysis of Longtitudinal Data', 'author': 'Diggle', 'year': '1994'} / Analysis of Longtitudinal Data by Diggle (1994)
10.1016/S0960-9822(06)00023-6 / Curr. Biol. / A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos by Drechsel (1997)
10.1083/jcb.131.1.151 / J. Cell Biol. / CDC42 and Rac1 control different actin-dependent processes in the Drosophila wing disc epithelium by Eaton (1995)
10.1016/S0960-9822(00)00645-X / Curr. Biol. / Nuclear signaling by Rac and Rho GTPases is required in the establishment of epithelial planar polarity in the Drosophila eye by Fanto (2000)
10.1101/gad.1022203 / Genes Dev. / Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation by Habas (2003)
10.1016/S0092-8674(01)00614-6 / Cell / Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1 by Habas (2001)
10.1101/gad.12.2.274 / Genes Dev. / DRhoGEF2 encodes a member of the Db1 family of oncogenes and controls cell shape changes during gastrulation in Drosophila by Hacker (1998)
10.1098/rstb.2000.0632 / Philos. Trans. R. Soc. Lond. B Biol. Sci. / Rho GTPases by Hall (2000)
10.1242/dev.121.3.903 / Development / A dominant inhibitory version of the small GTP-binding protein Rac disrupts cytoskeletal structures and inhibits developmental cell shape changes in Drosophila by Harden (1995)
10.1242/jcs.112.3.273 / J. Cell Sci. / Participation of small GTPases in dorsal closure of the Drosophila embryo by Harden (1999)
{'key': '10.1016/S0012-1606(03)00206-9_BIB19', 'first-page': '685', 'article-title': 'In situ hybridization', 'volume': 'Vol. 36', 'author': 'Harland', 'year': '1991'} / In situ hybridization by Harland (1991)
Hens, M.D., DeSimone, D.W., 1995. Molecular analysis and developmental expression of the focal adhesion kinase pp125FAK in Xenopus laevis. Dev. Biol. 170, 274–288 (10.1006/dbio.1995.1214)
10.1016/S0006-291X(02)02459-2 / Biochem. Biophys. Res. Commun. / Regulation of Xenopus embryonic cell adhesion by the small GTPase, rac by Hens (2002)
10.1016/S0092-8674(05)80020-0 / Cell / The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF by Hill (1995)
10.1177/30.10.6182185 / J. Histochem. Cytochem. / Color modification of diaminobenzidine (DAB) precipitation by metallic ions and its application for double immunohistochemistry by Hsu (1982)
10.1242/jcs.113.18.3267 / J. Cell Sci. / The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1 by Johansson (2000)
10.1182/blood.V99.6.2060 / Blood / The tumor vascular targeting agent combretastatin A-4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells by Kanthou (2002)
10.1126/science.1079478 / Science / Shaping the vertebrate body plan by polarized embryonic cell movements by Keller (2002)
10.1098/rstb.2000.0626 / Philos. Trans. R. Soc. Lond. B Biol. Sci. / Mechanisms of convergence and extension by cell intercalation by Keller (2000)
10.1016/S0070-2153(08)60532-3 / Curr. Top. Dev. Biol. / The cellular basis of amphibian gastrulation by Keller (1992)
10.1242/dev.125.23.4681 / Development / The role of paraxial protocadherin in selective adhesion and cell movements of the mesoderm during Xenopus gastrulation by Kim (1998)
10.1038/308067a0 / Nature / Monoclonal antibodies identify blastemal cells derived from dedifferentiating limb regeneration by Kintner (1984)
10.1006/dbio.2001.0513 / Dev. Biol. / ced-10 Rac and mig-2 function redundantly and act with unc-73 trio to control the orientation of vulval cell divisions and migrations in Caenorhabditis elegans by Kishore (2002)
10.1111/j.1471-4159.1984.tb12799.x / J. Neurochem. / A library of monoclonal antibodies to Torpedo cholinergic synaptosomes by Kushner (1984)
10.1242/dev.124.4.895 / Development / Microtubule disruption reveals that Spemann’s organizer is subdivided into two domains by the vegetal alignment zone by Lane (1997)
10.1242/dev.125.24.5055 / Development / A role for rhoB in the delamination of neural crest cells from the dorsal neural tube by Liu (1998)
10.1016/S0925-4773(02)00117-X / Mech. Dev. / cDNA cloning, sequence comparison, and developmental expression of Xenopus rac1 by Lucas (2002)
10.1242/dev.126.23.5353 / Development / Mutations in the Rho1 small GTPase disrupt morphogenesis and segmentation during early Drosophila development by Magie (1999)
10.1016/S0960-9822(02)00864-3 / Curr. Biol. / Zebrafish rho kinase 2 acts downstream of wnt11 to mediate cell polarity and effective convergence and extension movements by Marlow (2002)
10.1016/S0896-6273(00)80044-6 / Neuron / Labeling neural cells using adenoviral gene transfer of membrane-targeted GFP by Moriyoshi (1996)
{'key': '10.1016/S0012-1606(03)00206-9_BIB39', 'series-title': 'Normal Table of Xenopus laevis (Daudin)', 'author': 'Nieuwkoop', 'year': '1967'} / Normal Table of Xenopus laevis (Daudin) by Nieuwkoop (1967)
10.1042/bst0230456 / Biochem. Soc. Trans. / Rho, rac and cdc42 GTPases by Nobes (1995)
10.1016/0092-8674(95)90370-4 / Cell / Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia by Nobes (1995)
{'key': '10.1016/S0012-1606(03)00206-9_BIB42', 'first-page': '657', 'article-title': 'Solutions and protocols', 'volume': 'Vol. 36', 'author': 'Peng', 'year': '1991'} / Solutions and protocols by Peng (1991)
10.1101/gad.11.4.463 / Genes Dev. / Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins by Perona (1997)
{'key': '10.1016/S0012-1606(03)00206-9_BIB44', 'first-page': '111', 'article-title': 'Rho family proteins and cell migration', 'volume': '65', 'author': 'Ridley', 'year': '1999', 'journal-title': 'Biochem. Soc. Symp.'} / Biochem. Soc. Symp. / Rho family proteins and cell migration by Ridley (1999)
10.1016/0092-8674(92)90163-7 / Cell / The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors by Ridley (1992)
10.1016/0092-8674(92)90164-8 / Cell / The small GTP-binding protein rac regulates growth factor-induced membrane ruffling by Ridley (1992)
Rubin, D.B. (1991). Computational aspects of analysing random effects/longtitudinal models, in: Statistics in Medicine, Vol. 11, John Wiley and Sons, Ltd., New York, pp. 1809–1821 (10.1002/sim.4780111405)
10.1101/gad.8.11.1311 / Genes Dev. / Xenopus embryos regulate the nuclear localization of XMyoD by Rupp (1994)
10.1083/jcb.147.5.1009 / J. Cell Biol. / Rac downregulates Rho activity by Sander (1999)
10.1002/aja.1001970405 / Dev. Dyn. / Induction of neuronal differentiation by planar signals in Xenopus embryos by Sater (1993)
10.1006/excr.2000.5049 / Exp. Cell Res. / Rho GTPases by Schmitz (2000)
10.1016/S1534-5807(01)00053-3 / Dev. Cell / Rac ’n Rho by Settleman (2001)
10.1242/dev.116.4.901 / Development / Cell motility driving mediolateral intercalation in explants of Xenopus laevis by Shih (1992)
10.1242/dev.116.4.887 / Development / The epithelium of the dorsal marginal zone of Xenopus has organizer properties by Shih (1992)
10.1242/dev.116.4.915 / Development / Patterns of cell motility in the organizer and dorsal mesoderm of Xenopus laevis by Shih (1992)
10.1016/0092-8674(91)90573-H / Cell / Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction by Smith (1991)
10.1016/S0960-9822(96)00750-6 / Curr. Biol. / Analysis of Dishevelled signalling pathways during Xenopus development by Sokol (1996)
10.1038/387292a0 / Nature / The role of RhoA in tissue polarity and Frizzled signalling by Strutt (1997)
10.1038/sj.onc.1202595 / Oncogene / Rac1 is required for the formation of three germ layers during gastrulation by Sugihara (1998)
10.1083/jcb.127.4.1071 / J. Cell Biol. / Vinculin-deficient PC12 cell lines extend unstable lamellipodia and filopodia and have a reduced rate of neurite outgrowth by Varnum-Finney (1994)
10.1016/S0960-9822(01)00201-9 / Curr. Biol. / Calcium signaling during convergent extension in Xenopus by Wallingford (2001)
10.1016/S1534-5807(02)00197-1 / Dev. Cell / Convergent extension. The molecular control of polarized cell movement during embryonic development by Wallingford (2002)
10.1242/dev.128.13.2581 / Development / Xenopus Dishevelled signaling regulates both neural and mesodermal convergent extension by Wallingford (2001)
10.1038/35011077 / Nature / Dishevelled controls cell polarity during Xenopus gastrulation by Wallingford (2000)
10.1073/pnas.95.25.14821 / Proc. Natl. Acad. Sci. USA / Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures by Wang (1998)
10.1242/dev.127.16.3619 / Development / Jun mediates Frizzled-induced R3/R4 cell fate distinction and planar polarity determination in the Drosophila eye by Weber (2000)
10.1242/dev.126.16.3703 / Development / Vegetal rotation, a new gastrulation movement involved in the internalization of the mesoderm and endoderm in Xenopus by Winklbauer (1999)
10.1046/j.1432-0436.2002.700105.x / Differentiation / EphA4 catalytic activity causes inhibition of RhoA GTPase in Xenopus laevis embryos by Winning (2002)
10.1016/S0092-8674(01)00298-7 / Cell / Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton by Winter (2001)
10.1006/dbio.1995.1174 / Dev. Biol. / Heart development in Drosophila requires the segment polarity gene wingless by Wu (1995)
10.1242/dev.126.23.5339 / Development / Involvement of the small GTPases XRhoA and XRnd1 in cell adhesion and head formation in early Xenopus development by Wunnenberg-Stapleton (1999)
10.1083/jcb.144.2.351 / J. Cell Biol. / Analysis of C-cadherin regulation during tissue morphogenesis with an activating antibody by Zhong (1999)
10.1016/S0092-8674(00)80353-0 / Cell / Role of a new Rho family member in cell migration and axon guidance in C. elegans by Zipkin (1997)

Dates

Type	When
Created	22 years, 2 months ago (June 9, 2003, 3:53 p.m.)
Deposited	2 years, 6 months ago (Feb. 21, 2023, 2:26 a.m.)
Indexed	1 month, 2 weeks ago (July 16, 2025, 8 a.m.)
Issued	22 years, 2 months ago (July 1, 2003)
Published	22 years, 2 months ago (July 1, 2003)
Published Print	22 years, 2 months ago (July 1, 2003)

Funders 0

None

BibTeX

@article{Tahinci_2003, title={Distinct functions of Rho and Rac are required for convergent extension during Xenopus gastrulation}, volume={259}, ISSN={0012-1606}, url={http://dx.doi.org/10.1016/s0012-1606(03)00206-9}, DOI={10.1016/s0012-1606(03)00206-9}, number={2}, journal={Developmental Biology}, publisher={Elsevier BV}, author={Tahinci, Emilios and Symes, Karen}, year={2003}, month=jul, pages={318–335} }

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      "DOI": "10.1113/jphysiol.2001.013117",
      "article-title": "Rho and rho kinase modulation of barrier properties",
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      "author": "Adamson",
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      "volume": "121",
      "author": "Ataliotis",
      "year": "1995",
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      "article-title": "The Rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation",
      "volume": "91",
      "author": "Barrett",
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      "journal-title": "Cell"
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      "author": "Choi",
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      "author": "Crawford",
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      "volume": "131",
      "author": "Eaton",
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      "article-title": "Participation of small GTPases in dorsal closure of the Drosophila embryo",
      "volume": "112",
      "author": "Harden",
      "year": "1999",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB19",
      "first-page": "685",
      "article-title": "In situ hybridization",
      "volume": "Vol. 36",
      "author": "Harland",
      "year": "1991"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB20",
      "doi-asserted-by": "crossref",
      "unstructured": "Hens, M.D., DeSimone, D.W., 1995. Molecular analysis and developmental expression of the focal adhesion kinase pp125FAK in Xenopus laevis. Dev. Biol. 170, 274\u2013288",
      "DOI": "10.1006/dbio.1995.1214"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB21",
      "doi-asserted-by": "crossref",
      "first-page": "364",
      "DOI": "10.1016/S0006-291X(02)02459-2",
      "article-title": "Regulation of Xenopus embryonic cell adhesion by the small GTPase, rac",
      "volume": "298",
      "author": "Hens",
      "year": "2002",
      "journal-title": "Biochem. Biophys. Res. Commun."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB22",
      "doi-asserted-by": "crossref",
      "first-page": "1159",
      "DOI": "10.1016/S0092-8674(05)80020-0",
      "article-title": "The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF",
      "volume": "81",
      "author": "Hill",
      "year": "1995",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB23",
      "doi-asserted-by": "crossref",
      "first-page": "1079",
      "DOI": "10.1177/30.10.6182185",
      "article-title": "Color modification of diaminobenzidine (DAB) precipitation by metallic ions and its application for double immunohistochemistry",
      "volume": "30",
      "author": "Hsu",
      "year": "1982",
      "journal-title": "J. Histochem. Cytochem."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB24",
      "doi-asserted-by": "crossref",
      "first-page": "3267",
      "DOI": "10.1242/jcs.113.18.3267",
      "article-title": "The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1",
      "volume": "113",
      "author": "Johansson",
      "year": "2000",
      "journal-title": "J. Cell Sci."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB25",
      "doi-asserted-by": "crossref",
      "first-page": "2060",
      "DOI": "10.1182/blood.V99.6.2060",
      "article-title": "The tumor vascular targeting agent combretastatin A-4-phosphate induces reorganization of the actin cytoskeleton and early membrane blebbing in human endothelial cells",
      "volume": "99",
      "author": "Kanthou",
      "year": "2002",
      "journal-title": "Blood"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB26",
      "doi-asserted-by": "crossref",
      "first-page": "1950",
      "DOI": "10.1126/science.1079478",
      "article-title": "Shaping the vertebrate body plan by polarized embryonic cell movements",
      "volume": "298",
      "author": "Keller",
      "year": "2002",
      "journal-title": "Science"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB27",
      "doi-asserted-by": "crossref",
      "first-page": "897",
      "DOI": "10.1098/rstb.2000.0626",
      "article-title": "Mechanisms of convergence and extension by cell intercalation",
      "volume": "355",
      "author": "Keller",
      "year": "2000",
      "journal-title": "Philos. Trans. R. Soc. Lond. B Biol. Sci."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB28",
      "doi-asserted-by": "crossref",
      "first-page": "39",
      "DOI": "10.1016/S0070-2153(08)60532-3",
      "article-title": "The cellular basis of amphibian gastrulation",
      "volume": "27",
      "author": "Keller",
      "year": "1992",
      "journal-title": "Curr. Top. Dev. Biol."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB29",
      "doi-asserted-by": "crossref",
      "first-page": "4681",
      "DOI": "10.1242/dev.125.23.4681",
      "article-title": "The role of paraxial protocadherin in selective adhesion and cell movements of the mesoderm during Xenopus gastrulation",
      "volume": "125",
      "author": "Kim",
      "year": "1998",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB30",
      "doi-asserted-by": "crossref",
      "first-page": "67",
      "DOI": "10.1038/308067a0",
      "article-title": "Monoclonal antibodies identify blastemal cells derived from dedifferentiating limb regeneration",
      "volume": "308",
      "author": "Kintner",
      "year": "1984",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB31",
      "doi-asserted-by": "crossref",
      "first-page": "339",
      "DOI": "10.1006/dbio.2001.0513",
      "article-title": "ced-10 Rac and mig-2 function redundantly and act with unc-73 trio to control the orientation of vulval cell divisions and migrations in Caenorhabditis elegans",
      "volume": "241",
      "author": "Kishore",
      "year": "2002",
      "journal-title": "Dev. Biol."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB32",
      "doi-asserted-by": "crossref",
      "first-page": "775",
      "DOI": "10.1111/j.1471-4159.1984.tb12799.x",
      "article-title": "A library of monoclonal antibodies to Torpedo cholinergic synaptosomes",
      "volume": "43",
      "author": "Kushner",
      "year": "1984",
      "journal-title": "J. Neurochem."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB33",
      "doi-asserted-by": "crossref",
      "first-page": "895",
      "DOI": "10.1242/dev.124.4.895",
      "article-title": "Microtubule disruption reveals that Spemann\u2019s organizer is subdivided into two domains by the vegetal alignment zone",
      "volume": "124",
      "author": "Lane",
      "year": "1997",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB34",
      "doi-asserted-by": "crossref",
      "first-page": "5055",
      "DOI": "10.1242/dev.125.24.5055",
      "article-title": "A role for rhoB in the delamination of neural crest cells from the dorsal neural tube",
      "volume": "125",
      "author": "Liu",
      "year": "1998",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB35",
      "doi-asserted-by": "crossref",
      "first-page": "113",
      "DOI": "10.1016/S0925-4773(02)00117-X",
      "article-title": "cDNA cloning, sequence comparison, and developmental expression of Xenopus rac1",
      "volume": "115",
      "author": "Lucas",
      "year": "2002",
      "journal-title": "Mech. Dev."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB36",
      "doi-asserted-by": "crossref",
      "first-page": "5353",
      "DOI": "10.1242/dev.126.23.5353",
      "article-title": "Mutations in the Rho1 small GTPase disrupt morphogenesis and segmentation during early Drosophila development",
      "volume": "126",
      "author": "Magie",
      "year": "1999",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB37",
      "doi-asserted-by": "crossref",
      "first-page": "876",
      "DOI": "10.1016/S0960-9822(02)00864-3",
      "article-title": "Zebrafish rho kinase 2 acts downstream of wnt11 to mediate cell polarity and effective convergence and extension movements",
      "volume": "12",
      "author": "Marlow",
      "year": "2002",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB38",
      "doi-asserted-by": "crossref",
      "first-page": "255",
      "DOI": "10.1016/S0896-6273(00)80044-6",
      "article-title": "Labeling neural cells using adenoviral gene transfer of membrane-targeted GFP",
      "volume": "16",
      "author": "Moriyoshi",
      "year": "1996",
      "journal-title": "Neuron"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB39",
      "series-title": "Normal Table of Xenopus laevis (Daudin)",
      "author": "Nieuwkoop",
      "year": "1967"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB40",
      "doi-asserted-by": "crossref",
      "first-page": "456",
      "DOI": "10.1042/bst0230456",
      "article-title": "Rho, rac and cdc42 GTPases",
      "volume": "23",
      "author": "Nobes",
      "year": "1995",
      "journal-title": "Biochem. Soc. Trans."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB41",
      "doi-asserted-by": "crossref",
      "first-page": "53",
      "DOI": "10.1016/0092-8674(95)90370-4",
      "article-title": "Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia",
      "volume": "81",
      "author": "Nobes",
      "year": "1995",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB42",
      "first-page": "657",
      "article-title": "Solutions and protocols",
      "volume": "Vol. 36",
      "author": "Peng",
      "year": "1991"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB43",
      "doi-asserted-by": "crossref",
      "first-page": "463",
      "DOI": "10.1101/gad.11.4.463",
      "article-title": "Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins",
      "volume": "11",
      "author": "Perona",
      "year": "1997",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB44",
      "first-page": "111",
      "article-title": "Rho family proteins and cell migration",
      "volume": "65",
      "author": "Ridley",
      "year": "1999",
      "journal-title": "Biochem. Soc. Symp."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB45",
      "doi-asserted-by": "crossref",
      "first-page": "389",
      "DOI": "10.1016/0092-8674(92)90163-7",
      "article-title": "The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors",
      "volume": "70",
      "author": "Ridley",
      "year": "1992",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB46",
      "doi-asserted-by": "crossref",
      "first-page": "401",
      "DOI": "10.1016/0092-8674(92)90164-8",
      "article-title": "The small GTP-binding protein rac regulates growth factor-induced membrane ruffling",
      "volume": "70",
      "author": "Ridley",
      "year": "1992",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB47",
      "doi-asserted-by": "crossref",
      "unstructured": "Rubin, D.B. (1991). Computational aspects of analysing random effects/longtitudinal models, in: Statistics in Medicine, Vol. 11, John Wiley and Sons, Ltd., New York, pp. 1809\u20131821",
      "DOI": "10.1002/sim.4780111405"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB48",
      "doi-asserted-by": "crossref",
      "first-page": "1311",
      "DOI": "10.1101/gad.8.11.1311",
      "article-title": "Xenopus embryos regulate the nuclear localization of XMyoD",
      "volume": "8",
      "author": "Rupp",
      "year": "1994",
      "journal-title": "Genes Dev."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB49",
      "doi-asserted-by": "crossref",
      "first-page": "1009",
      "DOI": "10.1083/jcb.147.5.1009",
      "article-title": "Rac downregulates Rho activity",
      "volume": "147",
      "author": "Sander",
      "year": "1999",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB50",
      "doi-asserted-by": "crossref",
      "first-page": "268",
      "DOI": "10.1002/aja.1001970405",
      "article-title": "Induction of neuronal differentiation by planar signals in Xenopus embryos",
      "volume": "197",
      "author": "Sater",
      "year": "1993",
      "journal-title": "Dev. Dyn."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB51",
      "doi-asserted-by": "crossref",
      "first-page": "1",
      "DOI": "10.1006/excr.2000.5049",
      "article-title": "Rho GTPases",
      "volume": "261",
      "author": "Schmitz",
      "year": "2000",
      "journal-title": "Exp. Cell Res."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB52",
      "doi-asserted-by": "crossref",
      "first-page": "321",
      "DOI": "10.1016/S1534-5807(01)00053-3",
      "article-title": "Rac \u2019n Rho",
      "volume": "1",
      "author": "Settleman",
      "year": "2001",
      "journal-title": "Dev. Cell"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB53",
      "doi-asserted-by": "crossref",
      "first-page": "901",
      "DOI": "10.1242/dev.116.4.901",
      "article-title": "Cell motility driving mediolateral intercalation in explants of Xenopus laevis",
      "volume": "116",
      "author": "Shih",
      "year": "1992",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB54",
      "doi-asserted-by": "crossref",
      "first-page": "887",
      "DOI": "10.1242/dev.116.4.887",
      "article-title": "The epithelium of the dorsal marginal zone of Xenopus has organizer properties",
      "volume": "116",
      "author": "Shih",
      "year": "1992",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB55",
      "doi-asserted-by": "crossref",
      "first-page": "915",
      "DOI": "10.1242/dev.116.4.915",
      "article-title": "Patterns of cell motility in the organizer and dorsal mesoderm of Xenopus laevis",
      "volume": "116",
      "author": "Shih",
      "year": "1992",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB56",
      "doi-asserted-by": "crossref",
      "first-page": "79",
      "DOI": "10.1016/0092-8674(91)90573-H",
      "article-title": "Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction",
      "volume": "67",
      "author": "Smith",
      "year": "1991",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB57",
      "doi-asserted-by": "crossref",
      "first-page": "1456",
      "DOI": "10.1016/S0960-9822(96)00750-6",
      "article-title": "Analysis of Dishevelled signalling pathways during Xenopus development",
      "volume": "6",
      "author": "Sokol",
      "year": "1996",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB58",
      "doi-asserted-by": "crossref",
      "first-page": "292",
      "DOI": "10.1038/387292a0",
      "article-title": "The role of RhoA in tissue polarity and Frizzled signalling",
      "volume": "387",
      "author": "Strutt",
      "year": "1997",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB59",
      "doi-asserted-by": "crossref",
      "first-page": "3427",
      "DOI": "10.1038/sj.onc.1202595",
      "article-title": "Rac1 is required for the formation of three germ layers during gastrulation",
      "volume": "17",
      "author": "Sugihara",
      "year": "1998",
      "journal-title": "Oncogene"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB60",
      "doi-asserted-by": "crossref",
      "first-page": "1071",
      "DOI": "10.1083/jcb.127.4.1071",
      "article-title": "Vinculin-deficient PC12 cell lines extend unstable lamellipodia and filopodia and have a reduced rate of neurite outgrowth",
      "volume": "127",
      "author": "Varnum-Finney",
      "year": "1994",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB61",
      "doi-asserted-by": "crossref",
      "first-page": "652",
      "DOI": "10.1016/S0960-9822(01)00201-9",
      "article-title": "Calcium signaling during convergent extension in Xenopus",
      "volume": "11",
      "author": "Wallingford",
      "year": "2001",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB62",
      "doi-asserted-by": "crossref",
      "first-page": "695",
      "DOI": "10.1016/S1534-5807(02)00197-1",
      "article-title": "Convergent extension. The molecular control of polarized cell movement during embryonic development",
      "volume": "2",
      "author": "Wallingford",
      "year": "2002",
      "journal-title": "Dev. Cell"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB63",
      "doi-asserted-by": "crossref",
      "first-page": "2581",
      "DOI": "10.1242/dev.128.13.2581",
      "article-title": "Xenopus Dishevelled signaling regulates both neural and mesodermal convergent extension",
      "volume": "128",
      "author": "Wallingford",
      "year": "2001",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB64",
      "doi-asserted-by": "crossref",
      "first-page": "81",
      "DOI": "10.1038/35011077",
      "article-title": "Dishevelled controls cell polarity during Xenopus gastrulation",
      "volume": "405",
      "author": "Wallingford",
      "year": "2000",
      "journal-title": "Nature"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB65",
      "doi-asserted-by": "crossref",
      "first-page": "14821",
      "DOI": "10.1073/pnas.95.25.14821",
      "article-title": "Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures",
      "volume": "95",
      "author": "Wang",
      "year": "1998",
      "journal-title": "Proc. Natl. Acad. Sci. USA"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB66",
      "doi-asserted-by": "crossref",
      "first-page": "3619",
      "DOI": "10.1242/dev.127.16.3619",
      "article-title": "Jun mediates Frizzled-induced R3/R4 cell fate distinction and planar polarity determination in the Drosophila eye",
      "volume": "127",
      "author": "Weber",
      "year": "2000",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB67",
      "doi-asserted-by": "crossref",
      "first-page": "3703",
      "DOI": "10.1242/dev.126.16.3703",
      "article-title": "Vegetal rotation, a new gastrulation movement involved in the internalization of the mesoderm and endoderm in Xenopus",
      "volume": "126",
      "author": "Winklbauer",
      "year": "1999",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB68",
      "doi-asserted-by": "crossref",
      "first-page": "46",
      "DOI": "10.1046/j.1432-0436.2002.700105.x",
      "article-title": "EphA4 catalytic activity causes inhibition of RhoA GTPase in Xenopus laevis embryos",
      "volume": "70",
      "author": "Winning",
      "year": "2002",
      "journal-title": "Differentiation"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB69",
      "doi-asserted-by": "crossref",
      "first-page": "81",
      "DOI": "10.1016/S0092-8674(01)00298-7",
      "article-title": "Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton",
      "volume": "105",
      "author": "Winter",
      "year": "2001",
      "journal-title": "Cell"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB70",
      "doi-asserted-by": "crossref",
      "first-page": "619",
      "DOI": "10.1006/dbio.1995.1174",
      "article-title": "Heart development in Drosophila requires the segment polarity gene wingless",
      "volume": "169",
      "author": "Wu",
      "year": "1995",
      "journal-title": "Dev. Biol."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB71",
      "doi-asserted-by": "crossref",
      "first-page": "5339",
      "DOI": "10.1242/dev.126.23.5339",
      "article-title": "Involvement of the small GTPases XRhoA and XRnd1 in cell adhesion and head formation in early Xenopus development",
      "volume": "126",
      "author": "Wunnenberg-Stapleton",
      "year": "1999",
      "journal-title": "Development"
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB72",
      "doi-asserted-by": "crossref",
      "first-page": "351",
      "DOI": "10.1083/jcb.144.2.351",
      "article-title": "Analysis of C-cadherin regulation during tissue morphogenesis with an activating antibody",
      "volume": "144",
      "author": "Zhong",
      "year": "1999",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "10.1016/S0012-1606(03)00206-9_BIB73",
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